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Items: 42

1.

Improving Our Understanding of Salmonella enterica Serovar Paratyphi B through the Engineering and Testing of a Live Attenuated Vaccine Strain.

Higginson EE, Ramachandran G, Hazen TH, Kania DA, Rasko DA, Pasetti MF, Levine MM, Tennant SM.

mSphere. 2018 Nov 28;3(6). pii: e00474-18. doi: 10.1128/mSphere.00474-18.

2.

Temporal Variability of Escherichia coli Diversity in the Gastrointestinal Tracts of Tanzanian Children with and without Exposure to Antibiotics.

Richter TKS, Hazen TH, Lam D, Coles CL, Seidman JC, You Y, Silbergeld EK, Fraser CM, Rasko DA.

mSphere. 2018 Nov 7;3(6). pii: e00558-18. doi: 10.1128/mSphere.00558-18.

3.

A Novel Shigella Proteome Microarray Discriminates Targets of Human Antibody Reactivity following Oral Vaccination and Experimental Challenge.

Ndungo E, Randall A, Hazen TH, Kania DA, Trappl-Kimmons K, Liang X, Barry EM, Kotloff KL, Chakraborty S, Mani S, Rasko DA, Pasetti MF.

mSphere. 2018 Aug 1;3(4). pii: e00260-18. doi: 10.1128/mSphere.00260-18.

4.

Diversity among blaKPC-containing plasmids in Escherichia coli and other bacterial species isolated from the same patients.

Hazen TH, Mettus R, McElheny CL, Bowler SL, Nagaraj S, Doi Y, Rasko DA.

Sci Rep. 2018 Jul 6;8(1):10291. doi: 10.1038/s41598-018-28085-7.

5.

Phosphotyrosine-Mediated Regulation of Enterohemorrhagic Escherichia coli Virulence.

Robertson CD, Hazen TH, Kaper JB, Rasko DA, Hansen AM.

MBio. 2018 Feb 27;9(1). pii: e00097-18. doi: 10.1128/mBio.00097-18.

6.

Draft Genome Sequences of blaKPC-Containing Enterobacter aerogenes, Citrobacter freundii, and Citrobacter koseri Strains.

Hazen TH, Mettus RT, McElheny CL, Bowler SL, Doi Y, Rasko DA.

Genome Announc. 2018 Feb 22;6(8). pii: e00035-18. doi: 10.1128/genomeA.00035-18.

7.

Comparative transcriptomics of Aspergillus fumigatus strains upon exposure to human airway epithelial cells.

Watkins TN, Liu H, Chung M, Hazen TH, Dunning Hotopp JC, Filler SG, Bruno VM.

Microb Genom. 2018 Jan 18. doi: 10.1099/mgen.0.000154. [Epub ahead of print]

8.

The AraC Negative Regulator family modulates the activity of histone-like proteins in pathogenic bacteria.

Santiago AE, Yan MB, Hazen TH, Sauder B, Meza-Segura M, Rasko DA, Kendall MM, Ruiz-Perez F, Nataro JP.

PLoS Pathog. 2017 Aug 14;13(8):e1006545. doi: 10.1371/journal.ppat.1006545. eCollection 2017 Aug.

9.

Transcriptional Variation of Diverse Enteropathogenic Escherichia coli Isolates under Virulence-Inducing Conditions.

Hazen TH, Daugherty SC, Shetty AC, Nataro JP, Rasko DA.

mSystems. 2017 Jul 25;2(4). pii: e00024-17. doi: 10.1128/mSystems.00024-17. eCollection 2017 Jul-Aug.

10.

Characterization of a Large Antibiotic Resistance Plasmid Found in Enteropathogenic Escherichia coli Strain B171 and Its Relatedness to Plasmids of Diverse E. coli and Shigella Strains.

Hazen TH, Michalski J, Nagaraj S, Okeke IN, Rasko DA.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00995-17. doi: 10.1128/AAC.00995-17. Print 2017 Sep.

11.

Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli.

Hazen TH, Michalski J, Luo Q, Shetty AC, Daugherty SC, Fleckenstein JM, Rasko DA.

Sci Rep. 2017 Jun 14;7(1):3513. doi: 10.1038/s41598-017-03489-z.

12.

Genomic diversity of EPEC associated with clinical presentations of differing severity.

Hazen TH, Donnenberg MS, Panchalingam S, Antonio M, Hossain A, Mandomando I, Ochieng JB, Ramamurthy T, Tamboura B, Qureshi S, Quadri F, Zaidi A, Kotloff KL, Levine MM, Barry EM, Kaper JB, Rasko DA, Nataro JP.

Nat Microbiol. 2016 Jan 18;1:15014. doi: 10.1038/nmicrobiol.2015.14.

13.

An integrated genomic and transcriptomic survey of mucormycosis-causing fungi.

Chibucos MC, Soliman S, Gebremariam T, Lee H, Daugherty S, Orvis J, Shetty AC, Crabtree J, Hazen TH, Etienne KA, Kumari P, O'Connor TD, Rasko DA, Filler SG, Fraser CM, Lockhart SR, Skory CD, Ibrahim AS, Bruno VM.

Nat Commun. 2016 Jul 22;7:12218. doi: 10.1038/ncomms12218.

14.

Investigating the Relatedness of Enteroinvasive Escherichia coli to Other E. coli and Shigella Isolates by Using Comparative Genomics.

Hazen TH, Leonard SR, Lampel KA, Lacher DW, Maurelli AT, Rasko DA.

Infect Immun. 2016 Jul 21;84(8):2362-2371. doi: 10.1128/IAI.00350-16. Print 2016 Aug.

15.

Genome diversity of Shigella boydii.

Kania DA, Hazen TH, Hossain A, Nataro JP, Rasko DA.

Pathog Dis. 2016 Jun;74(4):ftw027. doi: 10.1093/femspd/ftw027. Epub 2016 Apr 6.

16.

Diarrhea, bacteremia and multiorgan dysfunction due to an extraintestinal pathogenic Escherichia coli strain with enteropathogenic E. coli genes.

Kessler R, Nisa S, Hazen TH, Horneman A, Amoroso A, Rasko DA, Donnenberg MS.

Pathog Dis. 2015 Nov;73(8):ftv076. doi: 10.1093/femspd/ftv076. Epub 2015 Sep 26.

17.

Comparative Genomics Provides Insight into the Diversity of the Attaching and Effacing Escherichia coli Virulence Plasmids.

Hazen TH, Kaper JB, Nataro JP, Rasko DA.

Infect Immun. 2015 Oct;83(10):4103-17. doi: 10.1128/IAI.00769-15. Epub 2015 Aug 3.

18.

RNA-Seq analysis of isolate- and growth phase-specific differences in the global transcriptomes of enteropathogenic Escherichia coli prototype isolates.

Hazen TH, Daugherty SC, Shetty A, Mahurkar AA, White O, Kaper JB, Rasko DA.

Front Microbiol. 2015 Jun 12;6:569. doi: 10.3389/fmicb.2015.00569. eCollection 2015.

19.

EHEC Genomics: Past, Present, and Future.

Sadiq SM, Hazen TH, Rasko DA, Eppinger M.

Microbiol Spectr. 2014 Aug;2(4):EHEC-0020-2013. doi: 10.1128/microbiolspec.EHEC-0020-2013. Review.

PMID:
26104203
20.

Bacterial Factors Associated with Lethal Outcome of Enteropathogenic Escherichia coli Infection: Genomic Case-Control Studies.

Donnenberg MS, Hazen TH, Farag TH, Panchalingam S, Antonio M, Hossain A, Mandomando I, Ochieng JB, Ramamurthy T, Tamboura B, Zaidi A, Levine MM, Kotloff K, Rasko DA, Nataro JP.

PLoS Negl Trop Dis. 2015 May 15;9(5):e0003791. doi: 10.1371/journal.pntd.0003791. eCollection 2015 May.

21.

Characterization of the pathogenome and phylogenomic classification of enteropathogenic Escherichia coli of the O157:non-H7 serotypes.

Sanjar F, Rusconi B, Hazen TH, Koenig SS, Mammel MK, Feng PC, Rasko DA, Eppinger M.

Pathog Dis. 2015 Jul;73(5). pii: ftv033. doi: 10.1093/femspd/ftv033. Epub 2015 May 10.

22.

Insights into the environmental reservoir of pathogenic Vibrio parahaemolyticus using comparative genomics.

Hazen TH, Lafon PC, Garrett NM, Lowe TM, Silberger DJ, Rowe LA, Frace M, Parsons MB, Bopp CA, Rasko DA, Sobecky PA.

Front Microbiol. 2015 Mar 24;6:204. doi: 10.3389/fmicb.2015.00204. eCollection 2015.

23.

Blocking yersiniabactin import attenuates extraintestinal pathogenic Escherichia coli in cystitis and pyelonephritis and represents a novel target to prevent urinary tract infection.

Brumbaugh AR, Smith SN, Subashchandrabose S, Himpsl SD, Hazen TH, Rasko DA, Mobley HL.

Infect Immun. 2015 Apr;83(4):1443-50. doi: 10.1128/IAI.02904-14. Epub 2015 Jan 26.

24.

Host-specific induction of Escherichia coli fitness genes during human urinary tract infection.

Subashchandrabose S, Hazen TH, Brumbaugh AR, Himpsl SD, Smith SN, Ernst RD, Rasko DA, Mobley HL.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18327-32. doi: 10.1073/pnas.1415959112. Epub 2014 Dec 8.

25.

Whole-genome assembly of Klebsiella pneumoniae coproducing NDM-1 and OXA-232 carbapenemases using single-molecule, real-time sequencing.

Doi Y, Hazen TH, Boitano M, Tsai YC, Clark TA, Korlach J, Rasko DA.

Antimicrob Agents Chemother. 2014 Oct;58(10):5947-53. doi: 10.1128/AAC.03180-14. Epub 2014 Jul 28.

26.

Draft Genome Sequences of Nine Enteropathogenic Escherichia coli Strains from Kenya.

Hazen TH, Humphrys MS, Ochieng JB, Parsons M, Bopp CA, O'Reilly CE, Mintz E, Rasko DA.

Genome Announc. 2014 Jun 12;2(3). pii: e00582-14. doi: 10.1128/genomeA.00582-14.

27.

Comparative genomics of an IncA/C multidrug resistance plasmid from Escherichia coli and Klebsiella isolates from intensive care unit patients and the utility of whole-genome sequencing in health care settings.

Hazen TH, Zhao L, Boutin MA, Stancil A, Robinson G, Harris AD, Rasko DA, Johnson JK.

Antimicrob Agents Chemother. 2014 Aug;58(8):4814-25. doi: 10.1128/AAC.02573-14. Epub 2014 Jun 9.

28.

H-NST induces LEE expression and the formation of attaching and effacing lesions in enterohemorrhagic Escherichia coli.

Levine JA, Hansen AM, Michalski JM, Hazen TH, Rasko DA, Kaper JB.

PLoS One. 2014 Jan 21;9(1):e86618. doi: 10.1371/journal.pone.0086618. eCollection 2014.

29.

Genome Sequence of Escherichia coli O157:H7 Strain 2886-75, Associated with the First Reported Case of Human Infection in the United States.

Sanjar F, Hazen TH, Shah SM, Koenig SS, Agrawal S, Daugherty S, Sadzewicz L, Tallon LJ, Mammel MK, Feng P, Soderlund R, Tarr PI, Debroy C, Dudley EG, Cebula TA, Ravel J, Fraser CM, Rasko DA, Eppinger M.

Genome Announc. 2014 Jan 9;2(1). pii: e01120-13. doi: 10.1128/genomeA.01120-13.

30.

Characterization of Klebsiella sp. strain 10982, a colonizer of humans that contains novel antibiotic resistance alleles and exhibits genetic similarities to plant and clinical Klebsiella isolates.

Hazen TH, Zhao L, Sahl JW, Robinson G, Harris AD, Rasko DA, Johnson JK.

Antimicrob Agents Chemother. 2014;58(4):1879-88. doi: 10.1128/AAC.01605-13. Epub 2014 Jan 6.

31.

In vitro evolution of an archetypal enteropathogenic Escherichia coli strain.

Nisa S, Hazen TH, Assatourian L, Nougayr├Ęde JP, Rasko DA, Donnenberg MS.

J Bacteriol. 2013 Oct;195(19):4476-83. doi: 10.1128/JB.00704-13. Epub 2013 Aug 2.

32.

Draft Genome Sequences of Three O157 Enteropathogenic Escherichia coli Isolates.

Hazen TH, Sahl JW, Fraser CM, Donnenberg MS, Scheutz F, Rasko DA.

Genome Announc. 2013 Jul 18;1(4). pii: e00516-13. doi: 10.1128/genomeA.00516-13.

33.

Refining the pathovar paradigm via phylogenomics of the attaching and effacing Escherichia coli.

Hazen TH, Sahl JW, Fraser CM, Donnenberg MS, Scheutz F, Rasko DA.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12810-5. doi: 10.1073/pnas.1306836110. Epub 2013 Jul 15.

34.

Draft genome sequences of five recent human uropathogenic Escherichia coli isolates.

Subashchandrabose S, Hazen TH, Rasko DA, Mobley HL.

Pathog Dis. 2013 Oct;69(1):66-70. Epub 2013 Oct 1.

35.

Genome sequence of Klebsiella oxytoca 11492-1, a nosocomial isolate possessing a FOX-5 AmpC ╬▓-lactamase.

Hazen TH, Robinson GL, Harris AD, Rasko DA, Johnson JK.

J Bacteriol. 2012 Jun;194(11):3028-9. doi: 10.1128/JB.00391-12.

36.

Draft genome sequences of the diarrheagenic Escherichia coli collection.

Hazen TH, Sahl JW, Redman JC, Morris CR, Daugherty SC, Chibucos MC, Sengamalay NA, Fraser-Liggett CM, Steinsland H, Whittam TS, Whittam B, Manning SD, Rasko DA.

J Bacteriol. 2012 Jun;194(11):3026-7. doi: 10.1128/JB.00426-12.

37.

The contribution of mobile genetic elements to the evolution and ecology of Vibrios.

Hazen TH, Pan L, Gu JD, Sobecky PA.

FEMS Microbiol Ecol. 2010 Dec;74(3):485-99. doi: 10.1111/j.1574-6941.2010.00937.x. Review.

38.

Rapid identification of Vibrio parahaemolyticus by whole-cell matrix-assisted laser desorption ionization-time of flight mass spectrometry.

Hazen TH, Martinez RJ, Chen Y, Lafon PC, Garrett NM, Parsons MB, Bopp CA, Sullards MC, Sobecky PA.

Appl Environ Microbiol. 2009 Nov;75(21):6745-56. doi: 10.1128/AEM.01171-09. Epub 2009 Sep 11.

39.

Horizontal gene transfer and mobile genetic elements in marine systems.

Sobecky PA, Hazen TH.

Methods Mol Biol. 2009;532:435-53. doi: 10.1007/978-1-60327-853-9_25. Review.

PMID:
19271200
40.

Inactivation of mismatch repair increases the diversity of Vibrio parahaemolyticus.

Hazen TH, Kennedy KD, Chen S, Yi SV, Sobecky PA.

Environ Microbiol. 2009 May;11(5):1254-66. doi: 10.1111/j.1462-2920.2008.01853.x. Epub 2009 Jan 22.

PMID:
19161434
41.

Sequence characterization and comparative analysis of three plasmids isolated from environmental Vibrio spp.

Hazen TH, Wu D, Eisen JA, Sobecky PA.

Appl Environ Microbiol. 2007 Dec;73(23):7703-10. Epub 2007 Oct 5.

42.

Nitrogen fixation by Vibrio parahaemolyticus and its implications for a new ecological niche.

Criminger JD, Hazen TH, Sobecky PA, Lovell CR.

Appl Environ Microbiol. 2007 Sep;73(18):5959-61. Epub 2007 Aug 3.

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