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Items: 8


Elucidating the Impact of CHO Cell Culture Media on Tryptophan Oxidation of a Monoclonal Antibody Through Gene Expression Analyses.

He L, Desai JX, Gao J, Hazeltine LB, Lian Z, Calley JN, Frye CC.

Biotechnol J. 2018 Oct;13(10):e1700254. doi: 10.1002/biot.201700254. Epub 2018 Apr 17.


Chemically defined media modifications to lower tryptophan oxidation of biopharmaceuticals.

Hazeltine LB, Knueven KM, Zhang Y, Lian Z, Olson DJ, Ouyang A.

Biotechnol Prog. 2016 Jan-Feb;32(1):178-88. doi: 10.1002/btpr.2195. Epub 2015 Dec 7.


Chemically defined, albumin-free human cardiomyocyte generation.

Lian X, Bao X, Zilberter M, Westman M, Fisahn A, Hsiao C, Hazeltine LB, Dunn KK, Kamp TJ, Palecek SP.

Nat Methods. 2015 Jul;12(7):595-6. doi: 10.1038/nmeth.3448. No abstract available.


Temporal impact of substrate mechanics on differentiation of human embryonic stem cells to cardiomyocytes.

Hazeltine LB, Badur MG, Lian X, Das A, Han W, Palecek SP.

Acta Biomater. 2014 Feb;10(2):604-12. doi: 10.1016/j.actbio.2013.10.033. Epub 2013 Nov 4.


Engineering the human pluripotent stem cell microenvironment to direct cell fate.

Hazeltine LB, Selekman JA, Palecek SP.

Biotechnol Adv. 2013 Nov 15;31(7):1002-19. doi: 10.1016/j.biotechadv.2013.03.002. Epub 2013 Mar 17. Review.


Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions.

Lian X, Zhang J, Azarin SM, Zhu K, Hazeltine LB, Bao X, Hsiao C, Kamp TJ, Palecek SP.

Nat Protoc. 2013 Jan;8(1):162-75. doi: 10.1038/nprot.2012.150. Epub 2012 Dec 20.


Effects of substrate mechanics on contractility of cardiomyocytes generated from human pluripotent stem cells.

Hazeltine LB, Simmons CS, Salick MR, Lian X, Badur MG, Han W, Delgado SM, Wakatsuki T, Crone WC, Pruitt BL, Palecek SP.

Int J Cell Biol. 2012;2012:508294. doi: 10.1155/2012/508294. Epub 2012 May 9.


Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling.

Lian X, Hsiao C, Wilson G, Zhu K, Hazeltine LB, Azarin SM, Raval KK, Zhang J, Kamp TJ, Palecek SP.

Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):E1848-57. doi: 10.1073/pnas.1200250109. Epub 2012 May 29.

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