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Items: 29

1.

Detection of HFE Haemochromatosis in the clinic and community using standard erythrocyte tests.

Adris N, Hazeldine S, Bentley P, Trinder D, Chua ACG, Powell LW, Ramm LE, Ramm GA, Olynyk JK.

Blood Cells Mol Dis. 2019 Feb;74:18-24. doi: 10.1016/j.bcmd.2018.10.003. Epub 2018 Oct 10.

PMID:
30340937
2.

Alcoholic liver disease - the extent of the problem and what you can do about it.

Hazeldine S, Hydes T, Sheron N.

Clin Med (Lond). 2015 Apr;15(2):179-85. doi: 10.7861/clinmedicine.15-2-179. Review.

3.

Development of functional poly(amido amine) CXCR4 antagonists with the ability to mobilize leukocytes and deliver nucleic acids.

Wang Y, Hazeldine ST, Li J, Oupický D.

Adv Healthc Mater. 2015 Apr 2;4(5):729-38. doi: 10.1002/adhm.201400608. Epub 2014 Dec 9.

PMID:
25491178
4.

Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer.

Zhu Y, Li J, Kanvinde S, Lin Z, Hazeldine S, Singh RK, Oupický D.

Mol Pharm. 2015 Feb 2;12(2):332-41. doi: 10.1021/mp500469n. Epub 2014 Aug 25.

5.

Current treatment options for alcohol-related liver disease.

Hazeldine S, Sheron N.

Curr Opin Gastroenterol. 2014 May;30(3):238-44. doi: 10.1097/MOG.0000000000000065. Review.

PMID:
24662843
6.

Polyamine-based small molecule epigenetic modulators.

Sharma SK, Hazeldine S, Crowley ML, Hanson A, Beattie R, Varghese S, Senanayake TM, Hirata A, Hirata F, Huang Y, Wu Y, Steinbergs N, Murray-Stewart T, Bytheway I, Casero RA Jr, Woster PM.

Medchemcomm. 2012;3(1):14-21. Epub 2011 Nov 26.

7.

Elevated serum ferritin - what should GPs know?

Goot K, Hazeldine S, Bentley P, Olynyk J, Crawford D.

Aust Fam Physician. 2012 Dec;41(12):945-9.

PMID:
23210117
8.

Cyclam-based polymeric copper chelators for gene delivery and potential PET imaging.

Li J, Zhu Y, Hazeldine ST, Firestine SM, Oupický D.

Biomacromolecules. 2012 Oct 8;13(10):3220-7. doi: 10.1021/bm3009999. Epub 2012 Sep 25.

9.

Low molecular weight amidoximes that act as potent inhibitors of lysine-specific demethylase 1.

Hazeldine S, Pachaiyappan B, Steinbergs N, Nowotarski S, Hanson AS, Casero RA Jr, Woster PM.

J Med Chem. 2012 Sep 13;55(17):7378-91. doi: 10.1021/jm3002845. Epub 2012 Sep 4.

10.

Dual-function CXCR4 antagonist polyplexes to deliver gene therapy and inhibit cancer cell invasion.

Li J, Zhu Y, Hazeldine ST, Li C, Oupický D.

Angew Chem Int Ed Engl. 2012 Aug 27;51(35):8740-3. doi: 10.1002/anie.201203463. Epub 2012 Jul 31. No abstract available.

11.

An unusual cause of syncope.

Hazeldine S, Przemioslo R.

QJM. 2013 Mar;106(3):269-70. doi: 10.1093/qjmed/hcs057. Epub 2012 Mar 28. No abstract available.

PMID:
22457428
12.

Alternative spermidine biosynthetic route is critical for growth of Campylobacter jejuni and is the dominant polyamine pathway in human gut microbiota.

Hanfrey CC, Pearson BM, Hazeldine S, Lee J, Gaskin DJ, Woster PM, Phillips MA, Michael AJ.

J Biol Chem. 2011 Dec 16;286(50):43301-12. doi: 10.1074/jbc.M111.307835. Epub 2011 Oct 24.

13.

Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: identification of compounds with triple uptake inhibitory activity as potential antidepressant agents.

Gopishetty B, Hazeldine S, Santra S, Johnson M, Modi G, Ali S, Zhen J, Reith M, Dutta A.

J Med Chem. 2011 Apr 28;54(8):2924-32. doi: 10.1021/jm200020a. Epub 2011 Mar 29.

14.

Predicting patient tolerance of endoscopy with conscious sedation.

Hazeldine S, Fritschi L, Forbes G.

Scand J Gastroenterol. 2010 Oct;45(10):1248-54. doi: 10.3109/00365521.2010.497939.

PMID:
20560818
15.

Autochthonous hepatitis E in Southwest England: natural history, complications and seasonal variation, and hepatitis E virus IgG seroprevalence in blood donors, the elderly and patients with chronic liver disease.

Dalton HR, Stableforth W, Thurairajah P, Hazeldine S, Remnarace R, Usama W, Farrington L, Hamad N, Sieberhagen C, Ellis V, Mitchell J, Hussaini SH, Banks M, Ijaz S, Bendall RP.

Eur J Gastroenterol Hepatol. 2008 Aug;20(8):784-90. doi: 10.1097/MEG.0b013e3282f5195a.

PMID:
18617784
16.

Distinct light-initiated gene expression and cell cycle programs in the shoot apex and cotyledons of Arabidopsis.

López-Juez E, Dillon E, Magyar Z, Khan S, Hazeldine S, de Jager SM, Murray JA, Beemster GT, Bögre L, Shanahan H.

Plant Cell. 2008 Apr;20(4):947-68. doi: 10.1105/tpc.107.057075. Epub 2008 Apr 18.

17.

Bioisosteric heterocyclic versions of 7-{[2-(4-phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: identification of highly potent and selective agonists for dopamine D3 receptor with potent in vivo activity.

Biswas S, Hazeldine S, Ghosh B, Parrington I, Kuzhikandathil E, Reith ME, Dutta AK.

J Med Chem. 2008 May 22;51(10):3005-19. doi: 10.1021/jm701524h. Epub 2008 Apr 12.

PMID:
18410082
18.

Autochthonous hepatitis E in Southwest England: a comparison with hepatitis A.

Dalton HR, Stableforth W, Hazeldine S, Thurairajah P, Ramnarace R, Warshow U, Ijaz S, Ellis V, Bendall R.

Eur J Clin Microbiol Infect Dis. 2008 Jul;27(7):579-85. doi: 10.1007/s10096-008-0480-z. Epub 2008 Feb 26.

PMID:
18299907
19.

The role of hepatitis E virus testing in drug-induced liver injury.

Dalton HR, Fellows HJ, Stableforth W, Joseph M, Thurairajah PH, Warshow U, Hazeldine S, Remnarace R, Ijaz S, Hussaini SH, Bendall RP.

Aliment Pharmacol Ther. 2007 Nov 15;26(10):1429-35. Epub 2007 Sep 7. Review.

20.

Locally acquired hepatitis E in chronic liver disease.

Dalton HR, Hazeldine S, Banks M, Ijaz S, Bendall R.

Lancet. 2007 Apr 14;369(9569):1260. doi: 10.1016/S0140-6736(07)60595-9. No abstract available.

PMID:
17434400
21.

The role of autophagy in the death of L1210 leukemia cells initiated by the new antitumor agents, XK469 and SH80.

Kessel D, Reiners JJ Jr, Hazeldine ST, Polin L, Horwitz JP.

Mol Cancer Ther. 2007 Jan;6(1):370-9.

23.

Synthesis and biological evaluation of conformationally constrained analogs of the antitumor agents XK469 and SH80. Part 5.

Hazeldine ST, Polin L, Kushner J, White K, Corbett TH, Horwitz JP.

Bioorg Med Chem. 2006 Apr 1;14(7):2462-7. Epub 2005 Dec 5.

PMID:
16337128
24.

Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4.

Hazeldine ST, Polin L, Kushner J, White K, Corbett TH, Horwitz JP.

Bioorg Med Chem. 2005 Jun 2;13(12):3910-20.

PMID:
15911307
25.
26.

II. Synthesis and biological evaluation of some bioisosteres and congeners of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

Hazeldine ST, Polin L, Kushner J, White K, Bouregeois NM, Crantz B, Palomino E, Corbett TH, Horwitz JP.

J Med Chem. 2002 Jul 4;45(14):3130-7.

PMID:
12086498
27.

Lack of in vitro-in vivo correlation of a novel investigational anticancer agent, SH 30.

Poondru S, Parchment RE, Purohit V, LoRusso P, Horwitz JP, Hazeldine ST, Polin L, Corbett T, Jasti BR.

Invest New Drugs. 2002 Feb;20(1):23-33.

PMID:
12003192
28.

Preclinical efficacy evaluations of XK-469: dose schedule, route and cross-resistance behavior in tumor bearing mice.

Polin L, White K, Kushner J, Paluch J, Simpson C, Pugh S, Edelstein MK, Hazeldine S, Fontana J, LoRusso P, Horwitz JP, Corbett TH.

Invest New Drugs. 2002 Feb;20(1):13-22.

PMID:
12003190
29.

Design, synthesis, and biological evaluation of analogues of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

Hazeldine ST, Polin L, Kushner J, Paluch J, White K, Edelstein M, Palomino E, Corbett TH, Horwitz JP.

J Med Chem. 2001 May 24;44(11):1758-76.

PMID:
11356111

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