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Items: 36

1.

Inhibitor selectivity of CNTs and ENTs.

Vaskó B, Juhász V, Tóth B, Kurunczi A, Fekete Z, Krisjanis Zolnerciks J, Kis E, Magnan R, Bidon-Chanal Badia A, Pastor-Anglada M, Hazai E, Bikadi Z, Fülöp F, Krajcsi P.

Xenobiotica. 2019 Jul;49(7):840-851. doi: 10.1080/00498254.2018.1501832. Epub 2018 Sep 12.

PMID:
30022699
2.

Three-dimensional structure of the human breast cancer resistance protein (BCRP/ABCG2) in an inward-facing conformation.

Rosenberg MF, Bikadi Z, Hazai E, Starborg T, Kelley L, Chayen NE, Ford RC, Mao Q.

Acta Crystallogr D Biol Crystallogr. 2015 Aug;71(Pt 8):1725-35. doi: 10.1107/S1399004715010676. Epub 2015 Jul 31.

3.

Syntheses and antiproliferative effects of D-homo- and D-secoestrones.

Mernyák E, Szabó J, Bacsa I, Huber J, Schneider G, Minorics R, Bózsity N, Zupkó I, Varga M, Bikádi Z, Hazai E, Wölfling J.

Steroids. 2014 Sep;87:128-36. doi: 10.1016/j.steroids.2014.05.015. Epub 2014 Jun 10.

PMID:
24928727
4.

A detailed study of antibacterial 3-acyltetramic acids and 3-acylpiperidine-2,4-diones.

Jeong YC, Bikadi Z, Hazai E, Moloney MG.

ChemMedChem. 2014 Aug;9(8):1826-37. doi: 10.1002/cmdc.201402093. Epub 2014 May 18.

PMID:
24838989
5.

Predicting substrates of the human breast cancer resistance protein using a support vector machine method.

Hazai E, Hazai I, Ragueneau-Majlessi I, Chung SP, Bikadi Z, Mao Q.

BMC Bioinformatics. 2013 Apr 15;14:130. doi: 10.1186/1471-2105-14-130.

6.

Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains.

Gyimesi M, Harami GM, Sarlós K, Hazai E, Bikádi Z, Kovács M.

Nucleic Acids Res. 2012 May;40(9):3952-63. doi: 10.1093/nar/gks008. Epub 2012 Jan 16.

7.

Disordered proteins and network disorder in network descriptions of protein structure, dynamics and function: hypotheses and a comprehensive review.

Csermely P, Sandhu KS, Hazai E, Hoksza Z, Kiss HJ, Miozzo F, Veres DV, Piazza F, Nussinov R.

Curr Protein Pept Sci. 2012 Feb;13(1):19-33. Review.

PMID:
22044146
8.

Predicting P-glycoprotein-mediated drug transport based on support vector machine and three-dimensional crystal structure of P-glycoprotein.

Bikadi Z, Hazai I, Malik D, Jemnitz K, Veres Z, Hari P, Ni Z, Loo TW, Clarke DM, Hazai E, Mao Q.

PLoS One. 2011;6(10):e25815. doi: 10.1371/journal.pone.0025815. Epub 2011 Oct 4.

9.

Evaluation of drug-human serum albumin binding interactions with support vector machine aided online automated docking.

Zsila F, Bikadi Z, Malik D, Hari P, Pechan I, Berces A, Hazai E.

Bioinformatics. 2011 Jul 1;27(13):1806-13. doi: 10.1093/bioinformatics/btr284. Epub 2011 May 18.

PMID:
21593135
10.

Identification of a polyoxometalate inhibitor of the DNA binding activity of Sox2.

Narasimhan K, Pillay S, Bin Ahmad NR, Bikadi Z, Hazai E, Yan L, Kolatkar PR, Pervushin K, Jauch R.

ACS Chem Biol. 2011 Jun 17;6(6):573-81. doi: 10.1021/cb100432x. Epub 2011 Mar 7.

PMID:
21344919
11.

Drug transport by breast cancer resistance protein.

Poguntke M, Hazai E, Fromm MF, Zolk O.

Expert Opin Drug Metab Toxicol. 2010 Nov;6(11):1363-84. doi: 10.1517/17425255.2010.519700. Epub 2010 Sep 27.

PMID:
20873966
12.

Functional adaptation of the switch-2 nucleotide sensor enables rapid processive translocation by myosin-5.

Nagy NT, Sakamoto T, Takács B, Gyimesi M, Hazai E, Bikádi Z, Sellers JR, Kovács M.

FASEB J. 2010 Nov;24(11):4480-90. doi: 10.1096/fj.10-163998. Epub 2010 Jul 14.

13.

Cyclodextrin KnowledgeBase a web-based service managing CD-ligand complexation data.

Hazai E, Hazai I, Demko L, Kovacs S, Malik D, Akli P, Hari P, Szeman J, Fenyvesi E, Benes E, Szente L, Bikadi Z.

J Comput Aided Mol Des. 2010 Aug;24(8):713-7. doi: 10.1007/s10822-010-9368-y. Epub 2010 Jun 3.

PMID:
20521083
14.

Application of the PM6 semi-empirical method to modeling proteins enhances docking accuracy of AutoDock.

Bikadi Z, Hazai E.

J Cheminform. 2009 Sep 11;1:15. doi: 10.1186/1758-2946-1-15.

15.

A comprehensive study on the 5-hydroxytryptamine(3A) receptor binding of agonists serotonin and m-chlorophenylbiguanidine.

Hazai E, Joshi P, Skoviak EC, Suryanarayanan A, Schulte MK, Bikadi Z.

Bioorg Med Chem. 2009 Aug 15;17(16):5796-805. doi: 10.1016/j.bmc.2009.07.022. Epub 2009 Jul 16.

PMID:
19640719
16.

[DockingServer: molecular docking calculations online].

Hazai E, Kovács S, Demkó L, Bikádi Z.

Acta Pharm Hung. 2009;79(1):17-21. Hungarian.

PMID:
19526678
17.

In silico description of differential enantioselectivity in methoxychlor O-demethylation by CYP2C enzymes.

Bikádi Z, Hazai E.

Biochim Biophys Acta. 2008 Sep;1780(9):1070-9. doi: 10.1016/j.bbagen.2008.06.001. Epub 2008 Jun 9.

PMID:
18585438
18.

Organogold complexes probe a large beta-barrel cavity for human serum alpha1-acid glycoprotein.

Zsila F, Bikádi Z, Hazai E, Simon A, Fitos I, Mády G.

Biochim Biophys Acta. 2008 Jul-Aug;1784(7-8):1106-14. doi: 10.1016/j.bbapap.2008.03.015. Epub 2008 Apr 15.

PMID:
18456008
19.

Homology modeling of breast cancer resistance protein (ABCG2).

Hazai E, Bikádi Z.

J Struct Biol. 2008 Apr;162(1):63-74. doi: 10.1016/j.jsb.2007.12.001. Epub 2007 Dec 15.

PMID:
18249138
20.

Cyclodextrin complexes: chiral recognition and complexation behaviour.

Bikádi Z, Iványi R, Szente L, Ilisz I, Hazai E.

Curr Drug Discov Technol. 2007 Dec;4(4):282-94.

PMID:
18045090
21.

Functional and structural characterization of a protein based on analysis of its hydrogen bonding network by hydrogen bonding plot.

Bikadi Z, Demko L, Hazai E.

Arch Biochem Biophys. 2007 May 15;461(2):225-34. Epub 2007 Mar 12.

PMID:
17391641
22.

Aggregation of cyclodextrins as an important factor to determine their complexation behavior.

Bikádi Z, Kurdi R, Balogh S, Szemán J, Hazai E.

Chem Biodivers. 2006 Nov;3(11):1266-78.

PMID:
17193241
23.

Molecular modeling of the non-covalent binding of the dietary tomato carotenoids lycopene and lycophyll, and selected oxidative metabolites with 5-lipoxygenase.

Hazai E, Bikádi Z, Zsila F, Lockwood SF.

Bioorg Med Chem. 2006 Oct 15;14(20):6859-67. Epub 2006 Jul 11.

PMID:
16837203
24.

Molecular modeling of non-covalent binding of homochiral (3S,3'S)-astaxanthin to matrix metalloproteinase-13 (MMP-13).

Bikádi Z, Hazai E, Zsila F, Lockwood SF.

Bioorg Med Chem. 2006 Aug 15;14(16):5451-8. Epub 2006 May 23.

PMID:
16716595
25.

Interactions of granisetron with an agonist-free 5-HT3A receptor model.

Joshi PR, Suryanarayanan A, Hazai E, Schulte MK, Maksay G, Bikádi Z.

Biochemistry. 2006 Jan 31;45(4):1099-105.

PMID:
16430206
26.
27.

Selective binding of coumarin enantiomers to human alpha1-acid glycoprotein genetic variants.

Hazai E, Visy J, Fitos I, Bikádi Z, Simonyi M.

Bioorg Med Chem. 2006 Mar 15;14(6):1959-65. Epub 2005 Nov 15.

PMID:
16290938
28.

Association of cytochrome P450 enzymes is a determining factor in their catalytic activity.

Hazai E, Bikádi Z, Simonyi M, Kupfer D.

J Comput Aided Mol Des. 2005 Apr;19(4):271-85.

PMID:
16163453
29.

Role of CYP2E1 in deramciclane metabolism.

Monostory K, Köhalmy K, Hazai E, Vereczkey L, Kóbori L.

Drug Metab Dispos. 2005 Nov;33(11):1717-22. Epub 2005 Jun 2.

PMID:
15932955
31.

Glucuronidation of the oxidative cytochrome P450-mediated phenolic metabolites of the endocrine disruptor pesticide: methoxychlor by human hepatic UDP-glucuronosyl transferases.

Hazai E, Gagne PV, Kupfer D.

Drug Metab Dispos. 2004 Jul;32(7):742-51. Erratum in: Drug Metab Dispos. 2004 Sep;32(9):1055.

PMID:
15205390
32.

Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors.

Monostory K, Hazai E, Vereczkey L.

Chem Biol Interact. 2004 Apr 15;147(3):331-40.

PMID:
15135088
33.

GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl)propionic acid] antagonist, is a CYP2E1 inducer.

Tamási V, Hazai E, Porsmyr-Palmertz M, Ingelman-Sundberg M, Vereczkey L, Monostory K.

Drug Metab Dispos. 2003 Nov;31(11):1310-4.

PMID:
14570761
34.

Reduction of toxic metabolite formation of acetaminophen.

Hazai E, Vereczkey L, Monostory K.

Biochem Biophys Res Commun. 2002 Mar 8;291(4):1089-94.

PMID:
11866476
35.

[About paracetamol again].

Hazai E, Monostory K, Bakos A, Zacher G, Vereczkey L.

Orv Hetil. 2001 Feb 18;142(7):345-9. Review. Hungarian.

PMID:
11243017
36.

[Human drug metabolizing enzymes III. Epoxide hydrolases, esterases, and amidases].

Hazai E, Róna K, Vereczkey L.

Acta Pharm Hung. 1999 Sep;69(4):208-12. Review. Hungarian.

PMID:
10544521

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