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Items: 1 to 50 of 105

1.

Osteocytes respond to particles of clinically-relevant conventional and cross-linked polyethylene and metal alloys by up-regulation of resorptive and inflammatory pathways.

Ormsby RT, Solomon LB, Yang D, Crotti TN, Haynes DR, Findlay DM, Atkins GJ.

Acta Biomater. 2019 Mar 15;87:296-306. doi: 10.1016/j.actbio.2019.01.047. Epub 2019 Jan 25.

PMID:
30690207
2.

4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish.

Fierro J Jr, Haynes DR, Washbourne P.

PLoS One. 2018 Oct 4;13(10):e0205255. doi: 10.1371/journal.pone.0205255. eCollection 2018.

3.

Yeast RNA extract suppresses human osteoclast resorption in vitro.

Cantley MD, Rainsford KD, Haynes DR.

Inflammopharmacology. 2017 Apr 26. doi: 10.1007/s10787-017-0351-2. [Epub ahead of print]

PMID:
28447177
4.

Histone deacetylases (HDAC) in physiological and pathological bone remodelling.

Cantley MD, Zannettino ACW, Bartold PM, Fairlie DP, Haynes DR.

Bone. 2017 Feb;95:162-174. doi: 10.1016/j.bone.2016.11.028. Epub 2016 Nov 30. Review.

PMID:
27913271
5.

Evidence that osteocyte perilacunar remodelling contributes to polyethylene wear particle induced osteolysis.

Ormsby RT, Cantley M, Kogawa M, Solomon LB, Haynes DR, Findlay DM, Atkins GJ.

Acta Biomater. 2016 Mar;33:242-51. doi: 10.1016/j.actbio.2016.01.016. Epub 2016 Jan 18.

PMID:
26796208
6.

The effects of tumour necrosis factor-α on bone cells involved in periodontal alveolar bone loss; osteoclasts, osteoblasts and osteocytes.

Algate K, Haynes DR, Bartold PM, Crotti TN, Cantley MD.

J Periodontal Res. 2016 Oct;51(5):549-66. doi: 10.1111/jre.12339. Epub 2015 Dec 15. Review.

PMID:
26667183
7.

Semaphorin-3a, neuropilin-1 and plexin-A1 in prosthetic-particle induced bone loss.

Saad S, Dharmapatni AASSK, Crotti TN, Cantley MD, Algate K, Findlay DM, Atkins GJ, Haynes DR.

Acta Biomater. 2016 Jan;30:311-318. doi: 10.1016/j.actbio.2015.11.025. Epub 2015 Nov 18.

PMID:
26602825
8.

The X-Linked Inhibitor of Apoptosis Protein Inhibitor Embelin Suppresses Inflammation and Bone Erosion in Collagen Antibody Induced Arthritis Mice.

Dharmapatni AA, Cantley MD, Marino V, Perilli E, Crotti TN, Smith MD, Haynes DR.

Mediators Inflamm. 2015;2015:564042. doi: 10.1155/2015/564042. Epub 2015 Aug 4.

9.

Osteoimmunology: Major and Costimulatory Pathway Expression Associated with Chronic Inflammatory Induced Bone Loss.

Crotti TN, Dharmapatni AA, Alias E, Haynes DR.

J Immunol Res. 2015;2015:281287. doi: 10.1155/2015/281287. Epub 2015 May 3. Review.

10.

Class I and II histone deacetylase expression in human chronic periodontitis gingival tissue.

Cantley MD, Dharmapatni AA, Algate K, Crotti TN, Bartold PM, Haynes DR.

J Periodontal Res. 2016 Apr;51(2):143-51. doi: 10.1111/jre.12290. Epub 2015 Jun 2.

PMID:
26031835
11.

Parthenolide reduces empty lacunae and osteoclastic bone surface resorption induced by polyethylene particles in a murine calvarial model of peri-implant osteolysis.

Zawawi MS, Marino V, Perilli E, Cantley MD, Xu J, Purdue PE, Dharmapatni AA, Haynes DR, Crotti TN.

J Biomed Mater Res A. 2015 Nov;103(11):3572-9. doi: 10.1002/jbm.a.35484. Epub 2015 May 29.

PMID:
25903444
12.

Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis.

Cantley MD, Fairlie DP, Bartold PM, Marino V, Gupta PK, Haynes DR.

Rheumatology (Oxford). 2015 Sep;54(9):1713-23. doi: 10.1093/rheumatology/kev022. Epub 2015 Mar 31.

PMID:
25832610
13.

Caffeic acid phenethyl ester abrogates bone resorption in a murine calvarial model of polyethylene particle-induced osteolysis.

Zawawi MS, Perilli E, Stansborough RL, Marino V, Cantley MD, Xu J, Dharmapatni AA, Haynes DR, Gibson RJ, Crotti TN.

Calcif Tissue Int. 2015 Jun;96(6):565-74. doi: 10.1007/s00223-015-9982-8. Epub 2015 Mar 25.

PMID:
25804981
14.

Quantifying not only bone loss, but also soft tissue swelling, in a murine inflammatory arthritis model using micro-computed tomography.

Perilli E, Cantley M, Marino V, Crotti TN, Smith MD, Haynes DR, Dharmapatni AA.

Scand J Immunol. 2015 Feb;81(2):142-50. doi: 10.1111/sji.12259.

15.

Periprosthetic osteolysis after total hip replacement: molecular pathology and clinical management.

Howie DW, Neale SD, Haynes DR, Holubowycz OT, McGee MA, Solomon LB, Callary SA, Atkins GJ, Findlay DM.

Inflammopharmacology. 2013 Dec;21(6):389-96. doi: 10.1007/s10787-013-0192-6. Epub 2013 Oct 15. Review.

PMID:
24127125
16.

Effects of Osteochondrin S and select connective tissue ribonucleinate components on human osteoclasts in vitro.

Cantley MD, Rainsford KD, Haynes DR.

J Pharm Pharmacol. 2013 Aug;65(8):1214-22. doi: 10.1111/jphp.12088. Epub 2013 Jun 20.

PMID:
23837589
17.

Professor Barrie Vernon-Roberts, AO, MD, BSc, PhD, FRCPath, FRCPA, FAOrthA (Hon), FRS.SA.

Rainsford KD, Haynes DR.

Inflammopharmacology. 2013 Aug;21(4):269-77. doi: 10.1007/s10787-013-0176-6. Epub 2013 Jul 4. Erratum in: Inflammopharmacology. 2013 Oct;21(5):387.

PMID:
23824627
18.

Comparison of the ability of chondroitin sulfate derived from bovine, fish and pigs to suppress human osteoclast activity in vitro.

Cantley MD, Rainsford KD, Haynes DR.

Inflammopharmacology. 2013 Dec;21(6):407-12. doi: 10.1007/s10787-013-0171-y. Epub 2013 May 4.

PMID:
23644893
19.

Antibacterial and immunomodulatory properties of azithromycin treatment implications for periodontitis.

Bartold PM, du Bois AH, Gannon S, Haynes DR, Hirsch RS.

Inflammopharmacology. 2013 Aug;21(4):321-38. doi: 10.1007/s10787-012-0165-1. Epub 2013 Feb 28. Review.

PMID:
23446952
20.

Epigenetic regulation of inflammation: progressing from broad acting histone deacetylase (HDAC) inhibitors to targeting specific HDACs.

Cantley MD, Haynes DR.

Inflammopharmacology. 2013 Aug;21(4):301-7. doi: 10.1007/s10787-012-0166-0. Epub 2013 Jan 23. Review.

PMID:
23341163
21.

The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints.

Crotti TN, Dharmapatni AA, Alias E, Zannettino AC, Smith MD, Haynes DR.

Arthritis Res Ther. 2012 Nov 12;14(6):R245. doi: 10.1186/ar4088.

22.

Effect of Porphyromonas gingivalis on citrullination of proteins by macrophages in vitro.

Marchant C, Smith MD, Proudman S, Haynes DR, Bartold PM.

J Periodontol. 2013 Sep;84(9):1272-80. doi: 10.1902/jop.2012.120103. Epub 2012 Oct 29.

PMID:
23106505
23.

Azithromycin suppresses human osteoclast formation and activity in vitro.

Gannon SC, Cantley MD, Haynes DR, Hirsch R, Bartold PM.

J Cell Physiol. 2013 May;228(5):1098-107. doi: 10.1002/jcp.24259.

PMID:
23065774
24.

Regulation of ITAM adaptor molecules and their receptors by inhibition of calcineurin-NFAT signalling during late stage osteoclast differentiation.

Zawawi MS, Dharmapatni AA, Cantley MD, McHugh KP, Haynes DR, Crotti TN.

Biochem Biophys Res Commun. 2012 Oct 19;427(2):404-9. doi: 10.1016/j.bbrc.2012.09.077. Epub 2012 Sep 20.

PMID:
23000414
25.

Expression of peptidylarginine deiminase-2 and -4, citrullinated proteins and anti-citrullinated protein antibodies in human gingiva.

Harvey GP, Fitzsimmons TR, Dhamarpatni AA, Marchant C, Haynes DR, Bartold PM.

J Periodontal Res. 2013 Apr;48(2):252-61. doi: 10.1111/jre.12002. Epub 2012 Sep 16.

PMID:
22978559
26.

Histone deacetylase inhibitors as suppressors of bone destruction in inflammatory diseases.

Cantley MD, Bartold PM, Fairlie DP, Rainsford KD, Haynes DR.

J Pharm Pharmacol. 2012 Jun;64(6):763-74. doi: 10.1111/j.2042-7158.2011.01421.x. Epub 2011 Dec 16. Review.

PMID:
22571254
27.

Polyethylene particles stimulate expression of ITAM-related molecules in peri-implant tissues and when stimulating osteoclastogenesis in vitro.

Alias E, Dharmapatni AS, Holding AC, Atkins GJ, Findlay DM, Howie DW, Crotti TN, Haynes DR.

Acta Biomater. 2012 Aug;8(8):3104-12. doi: 10.1016/j.actbio.2012.04.037. Epub 2012 Apr 30.

PMID:
22554886
28.

Role of polyethylene particles in peri-prosthetic osteolysis: A review.

Atkins GJ, Haynes DR, Howie DW, Findlay DM.

World J Orthop. 2011 Oct 18;2(10):93-101. doi: 10.5312/wjo.v2.i10.93.

29.

Osteoclast resorption of thermal spray hydoxyapatite coatings is influenced by surface topography.

Gross KA, Muller D, Lucas H, Haynes DR.

Acta Biomater. 2012 May;8(5):1948-56. doi: 10.1016/j.actbio.2012.01.023. Epub 2012 Jan 25.

PMID:
22307028
30.

Histone deacetylase inhibitors and periodontal bone loss.

Cantley MD, Bartold PM, Marino V, Fairlie DP, Le GT, Lucke AJ, Haynes DR.

J Periodontal Res. 2011 Dec;46(6):697-703. doi: 10.1111/j.1600-0765.2011.01392.x. Epub 2011 Jul 11.

PMID:
21745207
31.

TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis.

Dharmapatni AA, Smith MD, Crotti TN, Holding CA, Vincent C, Weedon HM, Zannettino AC, Zheng TS, Findlay DM, Atkins GJ, Haynes DR.

Arthritis Res Ther. 2011 Mar 24;13(2):R51. doi: 10.1186/ar3294.

32.

Pre-existing periodontitis exacerbates experimental arthritis in a mouse model.

Cantley MD, Haynes DR, Marino V, Bartold PM.

J Clin Periodontol. 2011 Jun;38(6):532-41. doi: 10.1111/j.1600-051X.2011.01714.x. Epub 2011 Mar 21.

PMID:
21434962
33.

Inhibitors of histone deacetylases in class I and class II suppress human osteoclasts in vitro.

Cantley MD, Fairlie DP, Bartold PM, Rainsford KD, Le GT, Lucke AJ, Holding CA, Haynes DR.

J Cell Physiol. 2011 Dec;226(12):3233-41. doi: 10.1002/jcp.22684.

PMID:
21344383
34.

The expression of RANKL and OPG in the various grades of osteoarthritic cartilage.

Upton AR, Holding CA, Dharmapatni AA, Haynes DR.

Rheumatol Int. 2012 Feb;32(2):535-40. doi: 10.1007/s00296-010-1733-6. Epub 2011 Jan 23.

PMID:
21259010
35.

Expression of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor, fibroblast growth factor-inducible 14 protein (Fn14), in healthy tissues and in tissues affected by periodontitis.

Kataria NG, Bartold PM, Dharmapatni AA, Atkins GJ, Holding CA, Haynes DR.

J Periodontal Res. 2010 Aug;45(4):564-73. doi: 10.1111/j.1600-0765.2010.01275.x. Epub 2010 Jun 10.

PMID:
20546112
36.

Effect of Porphyromonas gingivalis-induced inflammation on the development of rheumatoid arthritis.

Bartold PM, Marino V, Cantley M, Haynes DR.

J Clin Periodontol. 2010 May;37(5):405-11. doi: 10.1111/j.1600-051X.2010.01552.x.

PMID:
20507365
37.

Mechanisms and control of pathologic bone loss in periodontitis.

Bartold PM, Cantley MD, Haynes DR.

Periodontol 2000. 2010 Jun;53:55-69. doi: 10.1111/j.1600-0757.2010.00347.x. Review. No abstract available.

PMID:
20403105
38.

Inhibition of apoptosis in periodontitis.

Lucas H, Bartold PM, Dharmapatni AA, Holding CA, Haynes DR.

J Dent Res. 2010 Jan;89(1):29-33. doi: 10.1177/0022034509350708.

PMID:
19948942
39.

Biological responses of human osteoblasts and osteoclasts to flame-sprayed coatings of hydroxyapatite and fluorapatite blends.

Bhadang KA, Holding CA, Thissen H, McLean KM, Forsythe JS, Haynes DR.

Acta Biomater. 2010 Apr;6(4):1575-83. doi: 10.1016/j.actbio.2009.10.029. Epub 2009 Oct 24.

PMID:
19857609
40.

The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A2 inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis.

Cantley MD, Bartold PM, Marino V, Reid RC, Fairlie DP, Wyszynski RN, Zilm PS, Haynes DR.

J Periodontal Res. 2009 Jun;44(3):317-22.

PMID:
19462493
41.

The induction of a catabolic phenotype in human primary osteoblasts and osteocytes by polyethylene particles.

Atkins GJ, Welldon KJ, Holding CA, Haynes DR, Howie DW, Findlay DM.

Biomaterials. 2009 Aug;30(22):3672-81. doi: 10.1016/j.biomaterials.2009.03.035. Epub 2009 Apr 5.

PMID:
19349075
42.

Pro-inflammatory cytokines TNF-related weak inducer of apoptosis (TWEAK) and TNFalpha induce the mitogen-activated protein kinase (MAPK)-dependent expression of sclerostin in human osteoblasts.

Vincent C, Findlay DM, Welldon KJ, Wijenayaka AR, Zheng TS, Haynes DR, Fazzalari NL, Evdokiou A, Atkins GJ.

J Bone Miner Res. 2009 Aug;24(8):1434-49. doi: 10.1359/jbmr.090305.

43.

Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium.

Dharmapatni AA, Smith MD, Findlay DM, Holding CA, Evdokiou A, Ahern MJ, Weedon H, Chen P, Screaton G, Xu XN, Haynes DR.

Arthritis Res Ther. 2009;11(1):R13. doi: 10.1186/ar2603. Epub 2009 Jan 27.

44.

The biologic response to particles from a potential disc prosthesis material.

Shimamura Y, Holding C, Haynes DR, Vernon-Roberts B, Blumbergs PC, Fraser RD, Moore RJ.

Spine (Phila Pa 1976). 2008 Feb 15;33(4):351-5. doi: 10.1097/BRS.0b013e318163f323.

PMID:
18277864
45.
46.

Inflammatory cells and bone loss in rheumatoid arthritis.

Haynes DR.

Arthritis Res Ther. 2007;9(3):104. Review.

47.

The similarities between birth plans and living wills.

Philipsen NC, Haynes DR.

J Perinat Educ. 2005 Fall;14(4):46-8.

48.

Emerging and future therapies for the treatment of bone loss associated with chronic inflammation.

Haynes DR.

Inflammopharmacology. 2006 Dec;14(5-6):193-7. Review.

PMID:
17093901
49.

Mechanisms of bone loss in rheumatoid arthritis.

Findlay DM, Haynes DR.

Mod Rheumatol. 2005;15(4):232-40.

PMID:
17029071
50.

The correlation of RANK, RANKL and TNFalpha expression with bone loss volume and polyethylene wear debris around hip implants.

Holding CA, Findlay DM, Stamenkov R, Neale SD, Lucas H, Dharmapatni AS, Callary SA, Shrestha KR, Atkins GJ, Howie DW, Haynes DR.

Biomaterials. 2006 Oct;27(30):5212-9. Epub 2006 Jun 27.

PMID:
16806459

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