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Patterns of use of the Mental Health Act 1983, from 2007-2008 to 2016-2017, in two major London secondary mental healthcare providers.

Oram S, Colling C, Pritchard M, Khondoker M, Fonseca de Freitas D, Ter-Minassian L, Downs J, Lloyd-Evans B, Markham S, Werbeloff N, Chang CK, Johnson S, Hotopf M, Hayes RD.

BJPsych Open. 2019 Nov 27;5(6):e102. doi: 10.1192/bjo.2019.84.


Psychiatric comorbidity as a risk factor for the mortality of people with bulimia nervosa.

Himmerich H, Hotopf M, Shetty H, Schmidt U, Treasure J, Hayes RD, Stewart R, Chang CK.

Soc Psychiatry Psychiatr Epidemiol. 2019 Jul;54(7):813-821. doi: 10.1007/s00127-019-01667-0. Epub 2019 Feb 11.


Risk of readmission in patients with schizophrenia and schizoaffective disorder newly prescribed clozapine.

Kesserwani J, Kadra G, Downs J, Shetty H, MacCabe JH, Taylor D, Stewart R, Chang CK, Hayes RD.

J Psychopharmacol. 2019 Apr;33(4):449-458. doi: 10.1177/0269881118817387. Epub 2019 Jan 8.


Clozapine and all-cause mortality in treatment-resistant schizophrenia: a historical cohort study.

Cho J, Hayes RD, Jewell A, Kadra G, Shetty H, MacCabe JH, Downs J.

Acta Psychiatr Scand. 2019 Mar;139(3):237-247. doi: 10.1111/acps.12989. Epub 2018 Dec 16.


The Aquilegia genome provides insight into adaptive radiation and reveals an extraordinarily polymorphic chromosome with a unique history.

Filiault DL, Ballerini ES, Mandáková T, Aköz G, Derieg NJ, Schmutz J, Jenkins J, Grimwood J, Shu S, Hayes RD, Hellsten U, Barry K, Yan J, Mihaltcheva S, Karafiátová M, Nizhynska V, Kramer EM, Lysak MA, Hodges SA, Nordborg M.

Elife. 2018 Oct 16;7. pii: e36426. doi: 10.7554/eLife.36426.


Predicting parkinsonism side-effects of antipsychotic polypharmacy prescribed in secondary mental healthcare.

Kadra G, Spiros A, Shetty H, Iqbal E, Hayes RD, Stewart R, Geerts H.

J Psychopharmacol. 2018 Nov;32(11):1191-1196. doi: 10.1177/0269881118796809. Epub 2018 Sep 20.


Psychiatric comorbidity as a risk factor for mortality in people with anorexia nervosa.

Himmerich H, Hotopf M, Shetty H, Schmidt U, Treasure J, Hayes RD, Stewart R, Chang CK.

Eur Arch Psychiatry Clin Neurosci. 2019 Apr;269(3):351-359. doi: 10.1007/s00406-018-0937-8. Epub 2018 Aug 17.


Long-term antipsychotic polypharmacy prescribing in secondary mental health care and the risk of mortality.

Kadra G, Stewart R, Shetty H, MacCabe JH, Chang CK, Taylor D, Hayes RD.

Acta Psychiatr Scand. 2018 Aug;138(2):123-132. doi: 10.1111/acps.12906. Epub 2018 May 29.


Integrating electronic healthcare records of armed forces personnel: Developing a framework for evaluating health outcomes in England, Scotland and Wales.

Leightley D, Chui Z, Jones M, Landau S, McCrone P, Hayes RD, Wessely S, Fear NT, Goodwin L.

Int J Med Inform. 2018 May;113:17-25. doi: 10.1016/j.ijmedinf.2018.02.012. Epub 2018 Feb 21.


Acute general hospital admissions in people with serious mental illness.

Jayatilleke N, Hayes RD, Chang CK, Stewart R.

Psychol Med. 2018 Dec;48(16):2676-2683. doi: 10.1017/S0033291718000284. Epub 2018 Feb 28.


Negative Symptoms in Early-Onset Psychosis and Their Association With Antipsychotic Treatment Failure.

Downs J, Dean H, Lechler S, Sears N, Patel R, Shetty H, Hotopf M, Ford T, Kyriakopoulos M, Diaz-Caneja CM, Arango C, MacCabe JH, Hayes RD, Pina-Camacho L.

Schizophr Bull. 2019 Jan 1;45(1):69-79. doi: 10.1093/schbul/sbx197.


The Physcomitrella patens chromosome-scale assembly reveals moss genome structure and evolution.

Lang D, Ullrich KK, Murat F, Fuchs J, Jenkins J, Haas FB, Piednoel M, Gundlach H, Van Bel M, Meyberg R, Vives C, Morata J, Symeonidi A, Hiss M, Muchero W, Kamisugi Y, Saleh O, Blanc G, Decker EL, van Gessel N, Grimwood J, Hayes RD, Graham SW, Gunter LE, McDaniel SF, Hoernstein SNW, Larsson A, Li FW, Perroud PF, Phillips J, Ranjan P, Rokshar DS, Rothfels CJ, Schneider L, Shu S, Stevenson DW, Thümmler F, Tillich M, Villarreal Aguilar JC, Widiez T, Wong GK, Wymore A, Zhang Y, Zimmer AD, Quatrano RS, Mayer KFX, Goodstein D, Casacuberta JM, Vandepoele K, Reski R, Cuming AC, Tuskan GA, Maumus F, Salse J, Schmutz J, Rensing SA.

Plant J. 2018 Feb;93(3):515-533. doi: 10.1111/tpj.13801.


Excess overdose mortality immediately following transfer of patients and their care as well as after cessation of opioid substitution therapy.

Bogdanowicz KM, Stewart R, Chang CK, Shetty H, Khondoker M, Day E, Hayes RD, Strang J.

Addiction. 2018 May;113(5):946-951. doi: 10.1111/add.14114. Epub 2018 Jan 10.


The Association Between Comorbid Autism Spectrum Disorders and Antipsychotic Treatment Failure in Early-Onset Psychosis: A Historical Cohort Study Using Electronic Health Records.

Downs JM, Lechler S, Dean H, Sears N, Patel R, Shetty H, Simonoff E, Hotopf M, Ford TJ, Diaz-Caneja CM, Arango C, MacCabe JH, Hayes RD, Pina-Camacho L.

J Clin Psychiatry. 2017 Nov/Dec;78(9):e1233-e1241. doi: 10.4088/JCP.16m11422.


Antipsychotic polypharmacy prescribing and risk of hospital readmission.

Kadra G, Stewart R, Shetty H, MacCabe JH, Chang CK, Kesserwani J, Taylor D, Hayes RD.

Psychopharmacology (Berl). 2018 Jan;235(1):281-289. doi: 10.1007/s00213-017-4767-6. Epub 2017 Oct 28.


Associations of acetylcholinesterase inhibitor treatment with reduced mortality in Alzheimer's disease: a retrospective survival analysis.

Mueller C, Perera G, Hayes RD, Shetty H, Stewart R.

Age Ageing. 2018 Jan 1;47(1):88-94. doi: 10.1093/ageing/afx098.


Contributions of specific causes of death to lost life expectancy in severe mental illness.

Jayatilleke N, Hayes RD, Dutta R, Shetty H, Hotopf M, Chang CK, Stewart R.

Eur Psychiatry. 2017 Jun;43:109-115. doi: 10.1016/j.eurpsy.2017.02.487. Epub 2017 Mar 17.


Linking health and education data to plan and evaluate services for children.

Downs J, Gilbert R, Hayes RD, Hotopf M, Ford T.

Arch Dis Child. 2017 Jul;102(7):599-602. doi: 10.1136/archdischild-2016-311656. Epub 2017 Jan 27. No abstract available.


Predictors of care home and hospital admissions and their costs for older people with Alzheimer's disease: findings from a large London case register.

Knapp M, Chua KC, Broadbent M, Chang CK, Fernandez JL, Milea D, Romeo R, Lovestone S, Spencer M, Thompson G, Stewart R, Hayes RD.

BMJ Open. 2016 Nov 18;6(11):e013591. doi: 10.1136/bmjopen-2016-013591.


Reasons for discontinuing clozapine: A cohort study of patients commencing treatment.

Legge SE, Hamshere M, Hayes RD, Downs J, O'Donovan MC, Owen MJ, Walters JTR, MacCabe JH.

Schizophr Res. 2016 Jul;174(1-3):113-119. doi: 10.1016/j.schres.2016.05.002. Epub 2016 May 19.


Identifying mortality risks in patients with opioid use disorder using brief screening assessment: Secondary mental health clinical records analysis.

Bogdanowicz KM, Stewart R, Chang CK, Downs J, Khondoker M, Shetty H, Strang J, Hayes RD.

Drug Alcohol Depend. 2016 Jul 1;164:82-88. doi: 10.1016/j.drugalcdep.2016.04.036. Epub 2016 May 6.


Predictors of long-term (≥6months) antipsychotic polypharmacy prescribing in secondary mental healthcare.

Kadra G, Stewart R, Shetty H, Downs J, MacCabe JH, Taylor D, Hayes RD.

Schizophr Res. 2016 Jul;174(1-3):106-112. doi: 10.1016/j.schres.2016.04.010. Epub 2016 Apr 16.


JBrowse: a dynamic web platform for genome visualization and analysis.

Buels R, Yao E, Diesh CM, Hayes RD, Munoz-Torres M, Helt G, Goodstein DM, Elsik CG, Lewis SE, Stein L, Holmes IH.

Genome Biol. 2016 Apr 12;17:66. doi: 10.1186/s13059-016-0924-1.


Cohort profile of the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Case Register: current status and recent enhancement of an Electronic Mental Health Record-derived data resource.

Perera G, Broadbent M, Callard F, Chang CK, Downs J, Dutta R, Fernandes A, Hayes RD, Henderson M, Jackson R, Jewell A, Kadra G, Little R, Pritchard M, Shetty H, Tulloch A, Stewart R.

BMJ Open. 2016 Mar 1;6(3):e008721. doi: 10.1136/bmjopen-2015-008721.


Antipsychotic polypharmacy and augmentation strategies prior to clozapine initiation: a historical cohort study of 310 adults with treatment-resistant schizophrenic disorders.

Thompson JV, Clark JM, Legge SE, Kadra G, Downs J, Walters JT, Hamshere ML, Hayes RD, Taylor D, MacCabe JH.

J Psychopharmacol. 2016 May;30(5):436-43. doi: 10.1177/0269881116632376. Epub 2016 Feb 23.


Associations between the schizophrenia susceptibility gene ZNF804A and clinical outcomes in psychosis.

Wickramasinghe A, Tulloch AD, Hayes RD, Chang CK, Broadbent M, Di Forti M, Murray RM, Iyegbe C, Stewart R.

Transl Psychiatry. 2015 Dec 15;5:e698. doi: 10.1038/tp.2015.198.


Clinical predictors of antipsychotic use in children and adolescents with autism spectrum disorders: a historical open cohort study using electronic health records.

Downs J, Hotopf M, Ford T, Simonoff E, Jackson RG, Shetty H, Stewart R, Hayes RD.

Eur Child Adolesc Psychiatry. 2016 Jun;25(6):649-58. doi: 10.1007/s00787-015-0780-7. Epub 2015 Oct 15.


Negative symptoms in schizophrenia: a study in a large clinical sample of patients using a novel automated method.

Patel R, Jayatilleke N, Broadbent M, Chang CK, Foskett N, Gorrell G, Hayes RD, Jackson R, Johnston C, Shetty H, Roberts A, McGuire P, Stewart R.

BMJ Open. 2015 Sep 7;5(9):e007619. doi: 10.1136/bmjopen-2015-007619.


Validation of the standardised assessment of personality--abbreviated scale in a general population sample.

Fok ML, Seegobin S, Frissa S, Hatch SL, Hotopf M, Hayes RD, Moran P.

Personal Ment Health. 2015 Nov;9(4):250-7. doi: 10.1002/pmh.1307. Epub 2015 Aug 27.


Extracting antipsychotic polypharmacy data from electronic health records: developing and evaluating a novel process.

Kadra G, Stewart R, Shetty H, Jackson RG, Greenwood MA, Roberts A, Chang CK, MacCabe JH, Hayes RD.

BMC Psychiatry. 2015 Jul 22;15:166. doi: 10.1186/s12888-015-0557-z.


The BioMart community portal: an innovative alternative to large, centralized data repositories.

Smedley D, Haider S, Durinck S, Pandini L, Provero P, Allen J, Arnaiz O, Awedh MH, Baldock R, Barbiera G, Bardou P, Beck T, Blake A, Bonierbale M, Brookes AJ, Bucci G, Buetti I, Burge S, Cabau C, Carlson JW, Chelala C, Chrysostomou C, Cittaro D, Collin O, Cordova R, Cutts RJ, Dassi E, Di Genova A, Djari A, Esposito A, Estrella H, Eyras E, Fernandez-Banet J, Forbes S, Free RC, Fujisawa T, Gadaleta E, Garcia-Manteiga JM, Goodstein D, Gray K, Guerra-Assunção JA, Haggarty B, Han DJ, Han BW, Harris T, Harshbarger J, Hastings RK, Hayes RD, Hoede C, Hu S, Hu ZL, Hutchins L, Kan Z, Kawaji H, Keliet A, Kerhornou A, Kim S, Kinsella R, Klopp C, Kong L, Lawson D, Lazarevic D, Lee JH, Letellier T, Li CY, Lio P, Liu CJ, Luo J, Maass A, Mariette J, Maurel T, Merella S, Mohamed AM, Moreews F, Nabihoudine I, Ndegwa N, Noirot C, Perez-Llamas C, Primig M, Quattrone A, Quesneville H, Rambaldi D, Reecy J, Riba M, Rosanoff S, Saddiq AA, Salas E, Sallou O, Shepherd R, Simon R, Sperling L, Spooner W, Staines DM, Steinbach D, Stone K, Stupka E, Teague JW, Dayem Ullah AZ, Wang J, Ware D, Wong-Erasmus M, Youens-Clark K, Zadissa A, Zhang SJ, Kasprzyk A.

Nucleic Acids Res. 2015 Jul 1;43(W1):W589-98. doi: 10.1093/nar/gkv350. Epub 2015 Apr 20.


Double trouble: Psychiatric comorbidity and opioid addiction-all-cause and cause-specific mortality.

Bogdanowicz KM, Stewart R, Broadbent M, Hatch SL, Hotopf M, Strang J, Hayes RD.

Drug Alcohol Depend. 2015 Mar 1;148:85-92. doi: 10.1016/j.drugalcdep.2014.12.025. Epub 2015 Jan 3.


Mini-mental state examination as a predictor of mortality among older people referred to secondary mental healthcare.

Su YP, Chang CK, Hayes RD, Perera G, Broadbent M, To D, Hotopf M, Stewart R.

PLoS One. 2014 Sep 3;9(9):e105312. doi: 10.1371/journal.pone.0105312. eCollection 2014.


The effect of clozapine on premature mortality: an assessment of clinical monitoring and other potential confounders.

Hayes RD, Downs J, Chang CK, Jackson RG, Shetty H, Broadbent M, Hotopf M, Stewart R.

Schizophr Bull. 2015 May;41(3):644-55. doi: 10.1093/schbul/sbu120. Epub 2014 Aug 25.


Suicide completion in secondary mental healthcare: a comparison study between schizophrenia spectrum disorders and all other diagnoses.

Lopez-Morinigo JD, Fernandes AC, Chang CK, Hayes RD, Broadbent M, Stewart R, David AS, Dutta R.

BMC Psychiatry. 2014 Aug 1;14:213. doi: 10.1186/s12888-014-0213-z.


Predictors of natural and unnatural mortality among patients with personality disorder: evidence from a large UK case register.

Fok ML, Stewart R, Hayes RD, Moran P.

PLoS One. 2014 Jul 7;9(7):e100979. doi: 10.1371/journal.pone.0100979. eCollection 2014.


The genome of Eucalyptus grandis.

Myburg AA, Grattapaglia D, Tuskan GA, Hellsten U, Hayes RD, Grimwood J, Jenkins J, Lindquist E, Tice H, Bauer D, Goodstein DM, Dubchak I, Poliakov A, Mizrachi E, Kullan AR, Hussey SG, Pinard D, van der Merwe K, Singh P, van Jaarsveld I, Silva-Junior OB, Togawa RC, Pappas MR, Faria DA, Sansaloni CP, Petroli CD, Yang X, Ranjan P, Tschaplinski TJ, Ye CY, Li T, Sterck L, Vanneste K, Murat F, Soler M, Clemente HS, Saidi N, Cassan-Wang H, Dunand C, Hefer CA, Bornberg-Bauer E, Kersting AR, Vining K, Amarasinghe V, Ranik M, Naithani S, Elser J, Boyd AE, Liston A, Spatafora JW, Dharmwardhana P, Raja R, Sullivan C, Romanel E, Alves-Ferreira M, Külheim C, Foley W, Carocha V, Paiva J, Kudrna D, Brommonschenkel SH, Pasquali G, Byrne M, Rigault P, Tibbits J, Spokevicius A, Jones RC, Steane DA, Vaillancourt RE, Potts BM, Joubert F, Barry K, Pappas GJ, Strauss SH, Jaiswal P, Grima-Pettenati J, Salse J, Van de Peer Y, Rokhsar DS, Schmutz J.

Nature. 2014 Jun 19;510(7505):356-62. doi: 10.1038/nature13308. Epub 2014 Jun 11.


The impact of co-morbid personality disorder on use of psychiatric services and involuntary hospitalization in people with severe mental illness.

Fok ML, Stewart R, Hayes RD, Moran P.

Soc Psychiatry Psychiatr Epidemiol. 2014 Oct;49(10):1631-40. doi: 10.1007/s00127-014-0874-4. Epub 2014 Apr 9.


Associations between risk of mortality and atypical antipsychotic use in vascular dementia: a clinical cohort study.

Sultana J, Chang CK, Hayes RD, Broadbent M, Stewart R, Corbett A, Ballard C.

Int J Geriatr Psychiatry. 2014 Dec;29(12):1249-54. doi: 10.1002/gps.4101. Epub 2014 Mar 14.


A cohort study on mental disorders, stage of cancer at diagnosis and subsequent survival.

Chang CK, Hayes RD, Broadbent MT, Hotopf M, Davies E, Møller H, Stewart R.

BMJ Open. 2014 Jan 29;4(1):e004295. doi: 10.1136/bmjopen-2013-004295.


TextHunter--A User Friendly Tool for Extracting Generic Concepts from Free Text in Clinical Research.

Jackson MSc RG, Ball M, Patel R, Hayes RD, Dobson RJ, Stewart R.

AMIA Annu Symp Proc. 2014 Nov 14;2014:729-38. eCollection 2014.


Retrospective chart review on exposure to psychotropic medications associated with neuroleptic malignant syndrome.

Su YP, Chang CK, Hayes RD, Harrison S, Lee W, Broadbent M, Taylor D, Stewart R.

Acta Psychiatr Scand. 2014 Jul;130(1):52-60. doi: 10.1111/acps.12222. Epub 2013 Nov 15.


Evaluation of smoking status identification using electronic health records and open-text information in a large mental health case register.

Wu CY, Chang CK, Robson D, Jackson R, Chen SJ, Hayes RD, Stewart R.

PLoS One. 2013 Sep 12;8(9):e74262. doi: 10.1371/journal.pone.0074262. eCollection 2013.


Comparisons of polydrug use at national and inner city levels in England: associations with demographic and socioeconomic factors.

Carter JL, Strang J, Frissa S, Hayes RD; SELCoH Study Team, Hatch SL, Hotopf M.

Ann Epidemiol. 2013 Oct;23(10):636-45. doi: 10.1016/j.annepidem.2013.07.012. Epub 2013 Aug 15.


Development and evaluation of a de-identification procedure for a case register sourced from mental health electronic records.

Fernandes AC, Cloete D, Broadbent MT, Hayes RD, Chang CK, Jackson RG, Roberts A, Tsang J, Soncul M, Liebscher J, Stewart R, Callard F.

BMC Med Inform Decis Mak. 2013 Jul 11;13:71. doi: 10.1186/1472-6947-13-71.


Abuse and other correlates of common mental disorders in youth: a cross-sectional study in Goa, India.

Fernandes AC, Hayes RD, Patel V.

Soc Psychiatry Psychiatr Epidemiol. 2013 Apr;48(4):515-23. doi: 10.1007/s00127-012-0614-6. Epub 2012 Oct 31.


Functional status and all-cause mortality in serious mental illness.

Hayes RD, Chang CK, Fernandes AC, Begum A, To D, Broadbent M, Hotopf M, Stewart R.

PLoS One. 2012;7(9):e44613. doi: 10.1371/journal.pone.0044613. Epub 2012 Sep 6.


Life expectancy at birth and all-cause mortality among people with personality disorder.

Fok ML, Hayes RD, Chang CK, Stewart R, Callard FJ, Moran P.

J Psychosom Res. 2012 Aug;73(2):104-7. doi: 10.1016/j.jpsychores.2012.05.001. Epub 2012 May 26.


Associations between symptoms and all-cause mortality in individuals with serious mental illness.

Hayes RD, Chang CK, Fernandes A, Begum A, To D, Broadbent M, Hotopf M, Stewart R.

J Psychosom Res. 2012 Feb;72(2):114-9. doi: 10.1016/j.jpsychores.2011.09.012. Epub 2011 Nov 20.


Clinical risk assessment rating and all-cause mortality in secondary mental healthcare: the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) Case Register.

Wu CY, Chang CK, Hayes RD, Broadbent M, Hotopf M, Stewart R.

Psychol Med. 2012 Aug;42(8):1581-90. doi: 10.1017/S0033291711002698. Epub 2011 Dec 8.


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