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Items: 1 to 50 of 304

1.

Late-Stage Functionalization of Histidine in Unprotected Peptides.

Gopalakrishnan R, Noisier AFM, Johansson MJ, Knerr L, Hayes MA, Drury WJ 3rd, Valeur E, Malins LR.

Angew Chem Int Ed Engl. 2019 Oct 14. doi: 10.1002/anie.201910888. [Epub ahead of print]

PMID:
31609503
2.

Climate-driven regime shifts in a mangrove-salt marsh ecotone over the past 250 years.

Cavanaugh KC, Dangremond EM, Doughty CL, Williams AP, Parker JD, Hayes MA, Rodriguez W, Feller IC.

Proc Natl Acad Sci U S A. 2019 Oct 7. pii: 201902181. doi: 10.1073/pnas.1902181116. [Epub ahead of print]

3.

Australian vegetated coastal ecosystems as global hotspots for climate change mitigation.

Serrano O, Lovelock CE, B Atwood T, Macreadie PI, Canto R, Phinn S, Arias-Ortiz A, Bai L, Baldock J, Bedulli C, Carnell P, Connolly RM, Donaldson P, Esteban A, Ewers Lewis CJ, Eyre BD, Hayes MA, Horwitz P, Hutley LB, Kavazos CRJ, Kelleway JJ, Kendrick GA, Kilminster K, Lafratta A, Lee S, Lavery PS, Maher DT, Marbà N, Masque P, Mateo MA, Mount R, Ralph PJ, Roelfsema C, Rozaimi M, Ruhon R, Salinas C, Samper-Villarreal J, Sanderman J, J Sanders C, Santos I, Sharples C, Steven ADL, Cannard T, Trevathan-Tackett SM, Duarte CM.

Nat Commun. 2019 Oct 2;10(1):4313. doi: 10.1038/s41467-019-12176-8.

4.

Metabolism of Strained Rings: Glutathione S-transferase-Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation.

Li XQ, Grönberg G, Bangur EH, Hayes MA, Castagnoli N Jr, Weidolf L.

Drug Metab Dispos. 2019 Nov;47(11):1247-1256. doi: 10.1124/dmd.119.088658. Epub 2019 Sep 6.

PMID:
31492694
5.

Hip To Be Square: Oxetanes as Design Elements To Alter Metabolic Pathways.

Toselli F, Fredenwall M, Svensson P, Li XQ, Johansson A, Weidolf L, Hayes MA.

J Med Chem. 2019 Aug 22;62(16):7383-7399. doi: 10.1021/acs.jmedchem.9b00030. Epub 2019 Aug 2.

PMID:
31310524
6.

Identification of neural stem and progenitor cell subpopulations using DC insulator-based dielectrophoresis.

Liu Y, Jiang A, Kim E, Ro C, Adams T, Flanagan LA, Taylor TJ, Hayes MA.

Analyst. 2019 Jul 7;144(13):4066-4072. doi: 10.1039/c9an00456d. Epub 2019 Jun 5.

PMID:
31165125
7.

Isolation and identification of Listeria monocytogenes utilizing DC insulator-based dielectrophoresis.

Crowther CV, Hilton SH, Kemp L, Hayes MA.

Anal Chim Acta. 2019 Aug 30;1068:41-51. doi: 10.1016/j.aca.2019.03.019. Epub 2019 Mar 12.

PMID:
31072476
8.

Exploring the oxygen sensitivity of wetland soil carbon mineralization.

Chapman SK, Hayes MA, Kelly B, Langley JA.

Biol Lett. 2019 Jan 31;15(1):20180407. doi: 10.1098/rsbl.2018.0407.

PMID:
30958210
9.

A smart curtailment approach for reducing bat fatalities and curtailment time at wind energy facilities.

Hayes MA, Hooton LA, Gilland KL, Grandgent C, Smith RL, Lindsay SR, Collins JD, Schumacher SM, Rabie PA, Gruver JC, Goodrich-Mahoney J.

Ecol Appl. 2019 Jun;29(4):e01881. doi: 10.1002/eap.1881. Epub 2019 Apr 2.

PMID:
30939226
10.

Novel Chemical Series of 5-Lipoxygenase-Activating Protein Inhibitors for Treatment of Coronary Artery Disease.

Lemurell M, Ulander J, Emtenäs H, Winiwarter S, Broddefalk J, Swanson M, Hayes MA, Prieto Garcia L, Westin Eriksson A, Meuller J, Cassel J, Saarinen G, Yuan ZQ, Löfberg C, Karlsson S, Sundqvist M, Whatling C.

J Med Chem. 2019 May 9;62(9):4325-4349. doi: 10.1021/acs.jmedchem.8b02012. Epub 2019 Apr 15.

PMID:
30929436
11.

A mathematical model of dielectrophoretic data to connect measurements with cell properties.

Hilton SH, Hayes MA.

Anal Bioanal Chem. 2019 Apr;411(10):2223-2237. doi: 10.1007/s00216-019-01757-7. Epub 2019 Mar 16.

PMID:
30879117
12.

Discovery and Early Clinical Development of an Inhibitor of 5-Lipoxygenase Activating Protein (AZD5718) for Treatment of Coronary Artery Disease.

Pettersen D, Broddefalk J, Emtenäs H, Hayes MA, Lemurell M, Swanson M, Ulander J, Whatling C, Amilon C, Ericsson H, Westin Eriksson A, Granberg K, Plowright AT, Shamovsky I, Dellsèn A, Sundqvist M, Någård M, Lindstedt EL.

J Med Chem. 2019 May 9;62(9):4312-4324. doi: 10.1021/acs.jmedchem.8b02004. Epub 2019 Mar 26.

PMID:
30869888
13.

Simulation and experiment of asymmetric electrode placement for electrophoretic exclusion in a microdevice.

Zhu F, Hayes MA.

Electrophoresis. 2019 Jan;40(2):304-314. doi: 10.1002/elps.201700497. Epub 2018 Nov 6.

PMID:
30350873
14.

Modeling the distributions of tegu lizards in native and potential invasive ranges.

Jarnevich CS, Hayes MA, Fitzgerald LA, Yackel Adams AA, Falk BG, Collier MAM, Bonewell LR, Klug PE, Naretto S, Reed RN.

Sci Rep. 2018 Jul 5;8(1):10193. doi: 10.1038/s41598-018-28468-w.

15.

Assessing the potential impacts of a changing climate on the distribution of a rabies virus vector.

Hayes MA, Piaggio AJ.

PLoS One. 2018 Feb 21;13(2):e0192887. doi: 10.1371/journal.pone.0192887. eCollection 2018.

16.

Patterns of conceptus development and of progesterone concentrations in maternal blood preceding spontaneous early pregnancy failure in mares.

Betteridge KJ, Raeside JI, Waelchli RO, Christie HL, Hayes MA.

Reprod Fertil Dev. 2018 Jul;30(8):1066-1076. doi: 10.1071/RD17336.

PMID:
29309736
17.

Exploring PTDH-P450BM3 Variants for the Synthesis of Drug Metabolites.

Beyer N, Kulig JK, Fraaije MW, Hayes MA, Janssen DB.

Chembiochem. 2018 Feb 16;19(4):326-337. doi: 10.1002/cbic.201700470. Epub 2018 Jan 17.

PMID:
29181885
18.

Biofluid pretreatment using gradient insulator-based dielectrophoresis: separating cells from biomarkers.

Ding J, Woolley C, Hayes MA.

Anal Bioanal Chem. 2017 Nov;409(27):6405-6414. doi: 10.1007/s00216-017-0582-5. Epub 2017 Aug 29.

PMID:
28852806
19.

Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis.

Nilsson A, Peric A, Strimfors M, Goodwin RJA, Hayes MA, Andrén PE, Hilgendorf C.

Sci Rep. 2017 Jul 25;7(1):6352. doi: 10.1038/s41598-017-06583-4.

20.

Simulated bat populations erode when exposed to climate change projections for western North America.

Hayes MA, Adams RA.

PLoS One. 2017 Jul 7;12(7):e0180693. doi: 10.1371/journal.pone.0180693. eCollection 2017.

21.

Saccharin Aza Bioisosteres-Synthesis and Preclinical Property Comparisons.

Chen Y, Aurell CJ, Pettersen A, Lewis RJ, Hayes MA, Lepistö M, Jonson AC, Leek H, Thunberg L.

ACS Med Chem Lett. 2017 May 1;8(6):672-677. doi: 10.1021/acsmedchemlett.7b00137. eCollection 2017 Jun 8.

22.

Oxetane Substrates of Human Microsomal Epoxide Hydrolase.

Toselli F, Fredenwall M, Svensson P, Li XQ, Johansson A, Weidolf L, Hayes MA.

Drug Metab Dispos. 2017 Aug;45(8):966-973. doi: 10.1124/dmd.117.076489. Epub 2017 Jun 9.

PMID:
28600384
23.

Dynamics of sediment carbon stocks across intertidal wetland habitats of Moreton Bay, Australia.

Hayes MA, Jesse A, Hawke B, Baldock J, Tabet B, Lockington D, Lovelock CE.

Glob Chang Biol. 2017 Oct;23(10):4222-4234. doi: 10.1111/gcb.13722. Epub 2017 May 16.

PMID:
28407457
24.

Refinement of insulator-based dielectrophoresis.

Crowther CV, Hayes MA.

Analyst. 2017 May 2;142(9):1608-1618. doi: 10.1039/c6an02509a.

25.

Synthesis of 1β-hydroxydeoxycholic acid in H-2 and unlabeled forms.

Hayes MA, Roberts I, Grönberg G, Lv K, Lin B, Bergare J, Elmore CS.

J Labelled Comp Radiopharm. 2017 Apr;60(4):221-229. doi: 10.1002/jlcr.3495. Epub 2017 Mar 20.

PMID:
28183147
26.

Endothelial protein C receptor-dependent antichemotactic effects of canine protein C.

Wong VM, Côté O, Bienzle D, Hayes MA, Wood RD.

Am J Vet Res. 2017 Feb;78(2):186-194. doi: 10.2460/ajvr.78.2.186.

PMID:
28140640
27.

The self-sufficient P450 RhF expressed in a whole cell system selectively catalyses the 5-hydroxylation of diclofenac.

Klenk JM, Nebel BA, Porter JL, Kulig JK, Hussain SA, Richter SM, Tavanti M, Turner NJ, Hayes MA, Hauer B, Flitsch SL.

Biotechnol J. 2017 Mar;12(3). doi: 10.1002/biot.201600520. Epub 2017 Feb 8.

PMID:
28098428
28.

P450BM3 fused to phosphite dehydrogenase allows phosphite-driven selective oxidations.

Beyer N, Kulig JK, Bartsch A, Hayes MA, Janssen DB, Fraaije MW.

Appl Microbiol Biotechnol. 2017 Mar;101(6):2319-2331. doi: 10.1007/s00253-016-7993-7. Epub 2016 Nov 29.

29.

Sinusoidal endothelial cell and hepatic stellate cell phenotype correlates with stage of fibrosis in chronic liver disease in dogs.

Vince AR, Hayes MA, Jefferson BJ, Stalker MJ.

J Vet Diagn Invest. 2016 Sep;28(5):498-505. doi: 10.1177/1040638716658499. Epub 2016 Jul 16.

PMID:
27423735
30.

CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity.

Hayes MA, Li XQ, Grönberg G, Diczfalusy U, Andersson TB.

Drug Metab Dispos. 2016 Sep;44(9):1480-9. doi: 10.1124/dmd.116.070805. Epub 2016 Jul 11.

PMID:
27402728
31.

Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane.

Li XQ, Hayes MA, Grönberg G, Berggren K, Castagnoli N Jr, Weidolf L.

Drug Metab Dispos. 2016 Aug;44(8):1341-8. doi: 10.1124/dmd.116.071142. Epub 2016 Jun 2.

PMID:
27256986
32.

Concentration of Sindbis virus with optimized gradient insulator-based dielectrophoresis.

Ding J, Lawrence RM, Jones PV, Hogue BG, Hayes MA.

Analyst. 2016 Mar 21;141(6):1997-2008. doi: 10.1039/c5an02430g.

33.

Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data.

Iegre J, Hayes MA, Thompson RA, Weidolf L, Isin EM.

Drug Metab Dispos. 2016 May;44(5):732-40. doi: 10.1124/dmd.115.067850. Epub 2016 Feb 11.

PMID:
26868617
34.

Discovery of (3-(4-(2-Oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone (AZD1979), a Melanin Concentrating Hormone Receptor 1 (MCHr1) Antagonist with Favorable Physicochemical Properties.

Johansson A, Löfberg C, Antonsson M, von Unge S, Hayes MA, Judkins R, Ploj K, Benthem L, Lindén D, Brodin P, Wennerberg M, Fredenwall M, Li L, Persson J, Bergman R, Pettersen A, Gennemark P, Hogner A.

J Med Chem. 2016 Mar 24;59(6):2497-511. doi: 10.1021/acs.jmedchem.5b01654. Epub 2016 Feb 5.

PMID:
26741166
35.

Correction: Biophysical separation of Staphylococcus epidermidis strains based on antibiotic resistance.

Jones PV, Huey Hilton S, Davis PE, Yanashima R, McLemore R, McLaren A, Hayes MA.

Analyst. 2016 Jan 7;141(1):352. doi: 10.1039/c5an90100f. Epub 2015 Dec 2.

PMID:
26626370
36.

Sensitive Detection of Cardiac Biomarkers Using a Magnetic Microbead Immunoassay.

Woolley CF, Hayes MA.

Anal Methods. 2015 Oct 21;7(20):8632-8639. Epub 2015 Aug 20.

37.

Software-aided structural elucidation in drug discovery.

Ahlqvist M, Leandersson C, Hayes MA, Zamora I, Thompson RA.

Rapid Commun Mass Spectrom. 2015 Nov 15;29(21):2083-9. doi: 10.1002/rcm.7364.

PMID:
26443410
38.

Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons.

Rocha EM, Smith GA, Park E, Cao H, Brown E, Hayes MA, Beagan J, McLean JR, Izen SC, Perez-Torres E, Hallett PJ, Isacson O.

Neurobiol Dis. 2015 Oct;82:495-503. doi: 10.1016/j.nbd.2015.09.009. Epub 2015 Sep 25.

39.

Theoretical limitations of quantification for noncompetitive sandwich immunoassays.

Woolley CF, Hayes MA, Mahanti P, Douglass Gilman S, Taylor T.

Anal Bioanal Chem. 2015 Nov;407(28):8605-15. doi: 10.1007/s00216-015-9018-2. Epub 2015 Sep 5.

40.

A P450 fusion library of heme domains from Rhodococcus jostii RHA1 and its evaluation for the biotransformation of drug molecules.

Kulig JK, Spandolf C, Hyde R, Ruzzini AC, Eltis LD, Grönberg G, Hayes MA, Grogan G.

Bioorg Med Chem. 2015 Sep 1;23(17):5603-9. doi: 10.1016/j.bmc.2015.07.025. Epub 2015 Jul 21.

PMID:
26234905
41.

Seasonally-Dynamic Presence-Only Species Distribution Models for a Cryptic Migratory Bat Impacted by Wind Energy Development.

Hayes MA, Cryan PM, Wunder MB.

PLoS One. 2015 Jul 24;10(7):e0132599. doi: 10.1371/journal.pone.0132599. eCollection 2015.

42.

Targeting relational aggression in veterans: the Strength at Home Friends and Family intervention.

Hayes MA, Gallagher MW, Gilbert KS, Creech SK, DeCandia CJ, Beach CA, Taft CT.

J Clin Psychiatry. 2015 Jun;76(6):e774-8. doi: 10.4088/JCP.14m09155.

PMID:
26132685
43.

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice.

Rocha EM, Smith GA, Park E, Cao H, Graham AR, Brown E, McLean JR, Hayes MA, Beagan J, Izen SC, Perez-Torres E, Hallett PJ, Isacson O.

Antioxid Redox Signal. 2015 Aug 20;23(6):550-64. doi: 10.1089/ars.2015.6307. Epub 2015 Jul 29.

44.

Biophysical separation of Staphylococcus epidermidis strains based on antibiotic resistance.

Jones PV, Huey S, Davis P, Yanashima R, McLemore R, McLaren A, Hayes MA.

Analyst. 2015 Aug 7;140(15):5152-61. doi: 10.1039/c5an00906e. Erratum in: Analyst. 2016 Jan 7;141(1):352. Yanashima, Ryan [added].

45.

Focus on the London Dielectrophoresis 2014 meeting.

Lapizco-Encinas BH, Hayes MA.

Electrophoresis. 2015 May;36(9-10):1083. doi: 10.1002/elps.201570084. No abstract available.

PMID:
25974013
46.

Development of the resolution theory for gradient insulator-based dielectrophoresis.

Jones PV, Hayes MA.

Electrophoresis. 2015 May;36(9-10):1098-106. doi: 10.1002/elps.201400504. Epub 2015 May 5.

47.

Purification of protein C from canine plasma.

Wong VM, Bienzle D, Hayes MA, Taylor P, Wood RD.

BMC Vet Res. 2014 Oct 18;10:251. doi: 10.1186/s12917-014-0251-2.

48.

Treatment of PD-1(-/-) mice with amodiaquine and anti-CTLA4 leads to liver injury similar to idiosyncratic liver injury in patients.

Metushi IG, Hayes MA, Uetrecht J.

Hepatology. 2015 Apr;61(4):1332-42. doi: 10.1002/hep.27549. Epub 2015 Feb 23.

PMID:
25283142
50.

Development of the resolution theory for electrophoretic exclusion.

Kenyon SM, Keebaugh MW, Hayes MA.

Electrophoresis. 2014 Sep;35(18):2551-9. doi: 10.1002/elps.201300572. Epub 2014 Jul 21.

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