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Items: 21


Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19.

Asnani M, Hayer KE, Naqvi AS, Zheng S, Yang SY, Oldridge D, Ibrahim F, Maragkakis M, Gazzara MR, Black KL, Bagashev A, Taylor D, Mourelatos Z, Grupp SA, Barrett D, Maris JM, Sotillo E, Barash Y, Thomas-Tikhonenko A.

Leukemia. 2019 Oct 7. doi: 10.1038/s41375-019-0580-z. [Epub ahead of print] No abstract available.


Promotion of growth factor signaling as a critical function of β-catenin during HCC progression.

Kim E, Lisby A, Ma C, Lo N, Ehmer U, Hayer KE, Furth EE, Viatour P.

Nat Commun. 2019 Apr 23;10(1):1909. doi: 10.1038/s41467-019-09780-z.


Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma.

Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein P, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A.

Leukemia. 2019 Oct;33(10):2429-2441. doi: 10.1038/s41375-019-0454-4. Epub 2019 Mar 26.


Aberrant splicing in B-cell acute lymphoblastic leukemia.

Black KL, Naqvi AS, Asnani M, Hayer KE, Yang SY, Gillespie E, Bagashev A, Pillai V, Tasian SK, Gazzara MR, Carroll M, Taylor D, Lynch KW, Barash Y, Thomas-Tikhonenko A.

Nucleic Acids Res. 2019 Jan 25;47(2):1043. doi: 10.1093/nar/gky1231. No abstract available.


Aberrant splicing in B-cell acute lymphoblastic leukemia.

Black KL, Naqvi AS, Asnani M, Hayer KE, Yang SY, Gillespie E, Bagashev A, Pillai V, Tasian SK, Gazzara MR, Carroll M, Taylor D, Lynch KW, Barash Y, Thomas-Tikhonenko A.

Nucleic Acids Res. 2018 Nov 30;46(21):11357-11369. doi: 10.1093/nar/gky946. Erratum in: Nucleic Acids Res. 2019 Jan 25;47(2):1043.


A Cyfip2-Dependent Excitatory Interneuron Pathway Establishes the Innate Startle Threshold.

Marsden KC, Jain RA, Wolman MA, Echeverry FA, Nelson JC, Hayer KE, Miltenberg B, Pereda AE, Granato M.

Cell Rep. 2018 Apr 17;23(3):878-887. doi: 10.1016/j.celrep.2018.03.095.


A comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expression.

Lahens NF, Ricciotti E, Smirnova O, Toorens E, Kim EJ, Baruzzo G, Hayer KE, Ganguly T, Schug J, Grant GR.

BMC Genomics. 2017 Aug 10;18(1):602. doi: 10.1186/s12864-017-4011-0.


Cytosine Deaminase APOBEC3A Sensitizes Leukemia Cells to Inhibition of the DNA Replication Checkpoint.

Green AM, Budagyan K, Hayer KE, Reed MA, Savani MR, Wertheim GB, Weitzman MD.

Cancer Res. 2017 Sep 1;77(17):4579-4588. doi: 10.1158/0008-5472.CAN-16-3394. Epub 2017 Jun 27.


Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression.

Kim E, Cheng Y, Bolton-Gillespie E, Cai X, Ma C, Tarangelo A, Le L, Jambhekar M, Raman P, Hayer KE, Wertheim G, Speck NA, Tong W, Viatour P.

J Exp Med. 2017 Jul 3;214(7):1901-1912. doi: 10.1084/jem.20160719. Epub 2017 May 26.


Genomic Alterations of Non-Coding Regions Underlie Human Cancer: Lessons from T-ALL.

Rivera-Reyes A, Hayer KE, Bassing CH.

Trends Mol Med. 2016 Dec;22(12):1035-1046. doi: 10.1016/j.molmed.2016.10.004. Epub 2016 Oct 27. Review.


Simulation-based comprehensive benchmarking of RNA-seq aligners.

Baruzzo G, Hayer KE, Kim EJ, Di Camillo B, FitzGerald GA, Grant GR.

Nat Methods. 2017 Feb;14(2):135-139. doi: 10.1038/nmeth.4106. Epub 2016 Dec 12.


Benchmark analysis of algorithms for determining and quantifying full-length mRNA splice forms from RNA-seq data.

Hayer KE, Pizarro A, Lahens NF, Hogenesch JB, Grant GR.

Bioinformatics. 2015 Dec 15;31(24):3938-45. doi: 10.1093/bioinformatics/btv488. Epub 2015 Sep 3.


A genome-wide screen identifies PAPP-AA-mediated IGFR signaling as a novel regulator of habituation learning.

Wolman MA, Jain RA, Marsden KC, Bell H, Skinner J, Hayer KE, Hogenesch JB, Granato M.

Neuron. 2015 Mar 18;85(6):1200-11. doi: 10.1016/j.neuron.2015.02.025. Epub 2015 Mar 5. Erratum in: Neuron. 2015 Aug 19;87(4):906-7.


Zebrafish foxc1a drives appendage-specific neural circuit development.

Banerjee S, Hayer K, Hogenesch JB, Granato M.

Development. 2015 Feb 15;142(4):753-62. doi: 10.1242/dev.115816.


Germination of Aspergillus niger conidia is triggered by nitrogen compounds related to L-amino acids.

Hayer K, Stratford M, Archer DB.

Appl Environ Microbiol. 2014 Oct;80(19):6046-53. doi: 10.1128/AEM.01078-14. Epub 2014 Jul 25.


IVT-seq reveals extreme bias in RNA sequencing.

Lahens NF, Kavakli IH, Zhang R, Hayer K, Black MB, Dueck H, Pizarro A, Kim J, Irizarry R, Thomas RS, Grant GR, Hogenesch JB.

Genome Biol. 2014 Jun 30;15(6):R86. doi: 10.1186/gb-2014-15-6-r86.


Structural features of sugars that trigger or support conidial germination in the filamentous fungus Aspergillus niger.

Hayer K, Stratford M, Archer DB.

Appl Environ Microbiol. 2013 Nov;79(22):6924-31. doi: 10.1128/AEM.02061-13. Epub 2013 Aug 30.


Culture confirmation of tuberculosis cases in Birmingham, UK.

Hayer KS, Sitch AJ, Dedicoat M, Wood AL.

Scand J Infect Dis. 2013 Oct;45(10):746-51. doi: 10.3109/00365548.2013.804944. Epub 2013 Aug 19.


Extreme resistance to weak-acid preservatives in the spoilage yeast Zygosaccharomyces bailii.

Stratford M, Steels H, Nebe-von-Caron G, Novodvorska M, Hayer K, Archer DB.

Int J Food Microbiol. 2013 Aug 16;166(1):126-34. doi: 10.1016/j.ijfoodmicro.2013.06.025. Epub 2013 Jul 2.


Trancriptional landscape of Aspergillus niger at breaking of conidial dormancy revealed by RNA-sequencing.

Novodvorska M, Hayer K, Pullan ST, Wilson R, Blythe MJ, Stam H, Stratford M, Archer DB.

BMC Genomics. 2013 Apr 11;14:246. doi: 10.1186/1471-2164-14-246.


CircaDB: a database of mammalian circadian gene expression profiles.

Pizarro A, Hayer K, Lahens NF, Hogenesch JB.

Nucleic Acids Res. 2013 Jan;41(Database issue):D1009-13. doi: 10.1093/nar/gks1161. Epub 2012 Nov 24.

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