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Prednisone and Its Active Metabolite Prednisolone Attenuate Lipid Accumulation in Macrophages.
Jeries H, Volkova N, Grajeda-Iglesias C, Najjar M, Rosenblat M, Aviram M, Hayek T.
J Cardiovasc Pharmacol Ther. 2019 Oct 24:1074248419883591. doi: 10.1177/1074248419883591. [Epub ahead of print]
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A Comparative Study of the Reverse Sural Fascio-Cutaneous Flap Outcomes in the Management of Foot and Ankle Soft Tissue Defects in Diabetic and Trauma Patients.
Assi C, Samaha C, Chamoun Moussa M, Hayek T, Yammine K.
Foot Ankle Spec. 2019 Oct;12(5):432-438. doi: 10.1177/1938640018816378. Epub 2018 Dec 7.
Leucine supplementation attenuates macrophage foam-cell formation: Studies in humans, mice, and cultured macrophages.
Grajeda-Iglesias C, Rom O, Hamoud S, Volkova N, Hayek T, Abu-Saleh N, Aviram M.
Biofactors. 2018 May;44(3):245-262. doi: 10.1002/biof.1415. Epub 2018 Feb 5.
Heparanase Inhibition Reduces Glucose Levels, Blood Pressure, and Oxidative Stress in Apolipoprotein E Knockout Mice.
Hamoud S, Shekh Muhammad R, Abu-Saleh N, Hassan A, Zohar Y, Hayek T.
Biomed Res Int. 2017;2017:7357495. doi: 10.1155/2017/7357495. Epub 2017 Oct 26.
[REDUCTION OF ANTIBIOTIC CONSUMPTION IN RAMBAM HEALTH CARE CAMPUS - THE ROLE OF AN ANTIBIOTIC STEWARDSHIP PROGRAM].
Bitterman R, Raz-Pasteur A, Azzam ZS, Karban A, Levy Y, Hayek T, Braun E, Oren I, Bar-Lavi Y, Kassis I, Hussein K, Paul M.
Harefuah. 2017 Sep;156(9):573-577. Hebrew.
Atherogenicity of amino acids in the lipid-laden macrophage model system in vitro and in atherosclerotic mice: a key role for triglyceride metabolism.
Rom O, Grajeda-Iglesias C, Najjar M, Abu-Saleh N, Volkova N, Dar DE, Hayek T, Aviram M.
J Nutr Biochem. 2017 Jul;45:24-38. doi: 10.1016/j.jnutbio.2017.02.023. Epub 2017 Apr 6.
Acrolein increases macrophage atherogenicity in association with gut microbiota remodeling in atherosclerotic mice: protective role for the polyphenol-rich pomegranate juice.
Rom O, Korach-Rechtman H, Hayek T, Danin-Poleg Y, Bar H, Kashi Y, Aviram M.
Arch Toxicol. 2017 Apr;91(4):1709-1725. doi: 10.1007/s00204-016-1859-8. Epub 2016 Sep 30.
Supplementation with linoleic acid-rich soybean oil stimulates macrophage foam cell formation via increased oxidative stress and diacylglycerol acyltransferase1-mediated triglyceride biosynthesis.
Rom O, Jeries H, Hayek T, Aviram M.
Biofactors. 2017 Jan 2;43(1):100-116. doi: 10.1002/biof.1319. Epub 2016 Aug 12.
Aqueous or lipid components of atherosclerotic lesion increase macrophage oxidation and lipid accumulation.
Abu-Saleh N, Aviram M, Hayek T.
Life Sci. 2016 Jun 1;154:1-14. doi: 10.1016/j.lfs.2016.04.019. Epub 2016 Apr 23.
Paraoxonase 1 (PON1) and pomegranate influence circadian gene expression and period length.
Loizides-Mangold U, Koren-Gluzer M, Skarupelova S, Makhlouf AM, Hayek T, Aviram M, Dibner C.
Chronobiol Int. 2016;33(4):453-61. doi: 10.3109/07420528.2016.1154067. Epub 2016 Mar 24.
Paraoxonase 2 Induces a Phenotypic Switch in Macrophage Polarization Favoring an M2 Anti-Inflammatory State.
Koren-Gluzer M, Rosenblat M, Hayek T.
Int J Endocrinol. 2015;2015:915243. doi: 10.1155/2015/915243. Epub 2015 Dec 8.
CT scan-guided percutaneous osteosynthesis of a complex, multifocal fracture of the pelvic girdle in a 14-year-old adolescent.
Gagné PT, Bertrand AS, Caudal A, El Hayek T, Amoretti N.
Skeletal Radiol. 2014 Aug;43(8):1165-8. doi: 10.1007/s00256-014-1855-0. Epub 2014 Mar 20.
A significant correlation between C - reactive protein levels in blood monocytes derived macrophages versus content in carotid atherosclerotic lesions.
Kaplan M, Hamoud S, Tendler Y, Meilin E, Lazarovitch A, Nitecki S, Hayek T.
J Inflamm (Lond). 2014 Mar 3;11(1):7. doi: 10.1186/1476-9255-11-7.
Pomegranate extract (POMx) decreases the atherogenicity of serum and of human monocyte-derived macrophages (HMDM) in simvastatin-treated hypercholesterolemic patients: a double-blinded, placebo-controlled, randomized, prospective pilot study.
Hamoud S, Hayek T, Volkova N, Attias J, Moscoviz D, Rosenblat M, Aviram M.
Atherosclerosis. 2014 Jan;232(1):204-10. doi: 10.1016/j.atherosclerosis.2013.11.037. Epub 2013 Nov 19.
Metformin inhibits macrophage cholesterol biosynthesis rate: possible role for metformin-induced oxidative stress.
Koren-Gluzer M, Aviram M, Hayek T.
Biochem Biophys Res Commun. 2013 Sep 27;439(3):396-400. doi: 10.1016/j.bbrc.2013.08.062. Epub 2013 Aug 28.
Paraoxonase1 (PON1) reduces insulin resistance in mice fed a high-fat diet, and promotes GLUT4 overexpression in myocytes, via the IRS-1/Akt pathway.
Atherosclerosis. 2013 Jul;229(1):71-8. doi: 10.1016/j.atherosclerosis.2013.03.028. Epub 2013 Apr 10.
Chest pain unit in an internal medicine department: comparison of a year with the facility to a year without.
Hamoud S, Mahamid R, Halabi M, Lessick J, Abbadi S, Shreter R, Keidar Z, Aronson D, Hammerman H, Hayek T.
Isr Med Assoc J. 2013 Feb;15(2):79-84.
Felty's syndrome without rheumatoid arthritis?
Rozin A, Hoffman R, Hayek T, Balbir-Gurman A.
Clin Rheumatol. 2013 May;32(5):701-4. doi: 10.1007/s10067-012-2157-3. Epub 2013 Jan 5. Review.
Niacin administration significantly reduces oxidative stress in patients with hypercholesterolemia and low levels of high-density lipoprotein cholesterol.
Hamoud S, Kaplan M, Meilin E, Hassan A, Torgovicky R, Cohen R, Hayek T.
Am J Med Sci. 2013 Mar;345(3):195-9. doi: 10.1097/MAJ.0b013e3182548c28.
Oxidative stress and macrophage foam cell formation during diabetes mellitus-induced atherogenesis: role of insulin therapy.
Kaplan M, Aviram M, Hayek T.
Pharmacol Ther. 2012 Nov;136(2):175-85. doi: 10.1016/j.pharmthera.2012.08.002. Epub 2012 Aug 4. Review.
Elastic stable intramedullary nailing of tibial shaft fractures in children.
Griffet J, Leroux J, Boudjouraf N, Abou-Daher A, El Hayek T.
J Child Orthop. 2011 Aug;5(4):297-304. doi: 10.1007/s11832-011-0343-5. Epub 2011 Jun 2.
VLDL triglycerides inhibit HDL-associated paraoxonase 1 (PON1) activity: in vitro and in vivo studies.
Rosenblat M, Ward S, Volkova N, Hayek T, Aviram M.
Biofactors. 2012 Jul-Aug;38(4):292-9. doi: 10.1002/biof.1021. Epub 2012 Jun 4.
Recurrent Saccharomyces cerevisiae fungemia in an otherwise healthy patient.
Hamoud S, Keidar Z, Hayek T.
Isr Med Assoc J. 2011 Sep;13(9):575-6. No abstract available.
The antioxidant HDL-associated paraoxonase-1 (PON1) attenuates diabetes development and stimulates β-cell insulin release.
Koren-Gluzer M, Aviram M, Meilin E, Hayek T.
Atherosclerosis. 2011 Dec;219(2):510-8. doi: 10.1016/j.atherosclerosis.2011.07.119. Epub 2011 Aug 4.
Insulin increases macrophage triglyceride accumulation under diabetic conditions through the down regulation of hormone sensitive lipase and adipose triglyceride lipase.
Meilin E, Aviram M, Hayek T.
Biofactors. 2011 Mar-Apr;37(2):95-103. doi: 10.1002/biof.144. Epub 2011 Feb 22.
Percutaneous aspiration irrigation drainage technique in the management of septic arthritis in children.
Griffet J, Oborocianu I, Rubio A, Leroux J, Lauron J, Hayek T.
J Trauma. 2011 Feb;70(2):377-83. doi: 10.1097/TA.0b013e31820318f0.
Lumbopelvic stabilization with external fixator in a patient with lumbosacral agenesis.
Griffet J, Leroux J, El Hayek T.
Eur Spine J. 2011 Jul;20 Suppl 2:S161-5. doi: 10.1007/s00586-010-1458-y. Epub 2010 May 26.
Lytic bone lesion: presenting finding of sarcoidosis.
Hamoud S, Srour S, Fruchter O, Vlodavsky E, Hayek T.
Isr Med Assoc J. 2010 Jan;12(1):59-60. No abstract available.
High glucose upregulates C-reactive protein synthesis in macrophages.
Kaplan M, Tendler Y, Mahamid R, Shiner M, Aviram M, Hayek T.
Clin Chem. 2010 Jun;56(6):1036-8. doi: 10.1373/clinchem.2009.136838. Epub 2010 Mar 26. No abstract available.
Aspirin promotes low density lipoprotein susceptibility to oxidative modification in healthy volunteers.
Waterman M, Fuhrman B, Keidar S, Hayek T.
Isr Med Assoc J. 2009 Dec;11(12):730-4.
Apolipoprotein E and its role in aging and survival.
Bonomini F, Filippini F, Hayek T, Aviram M, Keidar S, Rodella LF, Coleman R, Rezzani R.
Exp Gerontol. 2010 Feb;45(2):149-57. doi: 10.1016/j.exger.2009.11.006. Epub 2009 Nov 24.
High glucose stimulates macrophage SR-BI expression and induces a switch in its activity from cholesterol efflux to cholesterol influx.
Gantman A, Fuhrman B, Aviram M, Hayek T.
Biochem Biophys Res Commun. 2010 Jan 1;391(1):523-8. doi: 10.1016/j.bbrc.2009.11.091. Epub 2009 Nov 23.
Paraoxonase 2 (PON2) decreases high glucose-induced macrophage triglycerides (TG) accumulation, via inhibition of NADPH-oxidase and DGAT1 activity: studies in PON2-deficient mice.
Atherosclerosis. 2010 Feb;208(2):390-5. doi: 10.1016/j.atherosclerosis.2009.07.057. Epub 2009 Aug 8.
Early reduction versus skin traction in the orthopaedic treatment of femoral shaft fractures in children under 6 years old.
d'Ollonne T, Rubio A, Leroux J, Lusakisimo S, Hayek T, Griffet J.
J Child Orthop. 2009 Jun;3(3):209-15. doi: 10.1007/s11832-009-0174-9. Epub 2009 May 13.
A too-long anterior process of the calcaneus: a report of 31 operated cases.
el Hayek T, D'Ollone T, Rubio A, Lusakisimo S, Griffet J.
J Pediatr Orthop B. 2009 Jul;18(4):163-6. doi: 10.1097/BPB.0b013e32832b14c5.
Images in clinical medicine. Postpartum venous thromboembolism.
Zalts R, Hayek T.
N Engl J Med. 2008 Dec 18;359(25):2706. doi: 10.1056/NEJMicm065130. No abstract available.
Phenolic antioxidants and antiatherogenic effects of Marula (Sclerocarrya birrea Subsp. caffra) fruit juice in healthy humans.
Borochov-Neori H, Judeinstein S, Greenberg A, Fuhrman B, Attias J, Volkova N, Hayek T, Aviram M.
J Agric Food Chem. 2008 Nov 12;56(21):9884-91. doi: 10.1021/jf801467m. Epub 2008 Oct 10.
Amphiphilic/Bipolar metallocorroles that catalyze the decomposition of reactive oxygen and nitrogen species, rescue lipoproteins from oxidative damage, and attenuate atherosclerosis in mice.
Haber A, Mahammed A, Fuhrman B, Volkova N, Coleman R, Hayek T, Aviram M, Gross Z.
Angew Chem Int Ed Engl. 2008;47(41):7896-900. doi: 10.1002/anie.200801149. No abstract available.
The moulded baby syndrome: incidence and risk factors regarding 1,001 neonates.
Rubio AS, Griffet JR, Caci H, Bérard E, El Hayek T, Boutté P.
Eur J Pediatr. 2009 May;168(5):605-11. doi: 10.1007/s00431-008-0806-y. Epub 2008 Sep 16.
High glucose concentration increases macrophage cholesterol biosynthesis in diabetes through activation of the sterol regulatory element binding protein 1 (SREBP1): inhibitory effect of insulin.
Kaplan M, Kerry R, Aviram M, Hayek T.
J Cardiovasc Pharmacol. 2008 Oct;52(4):324-32. doi: 10.1097/FJC.0b013e3181879d98.
Paraoxonase 1 (PON1) attenuates diabetes development in mice through its antioxidative properties.
Rozenberg O, Shiner M, Aviram M, Hayek T.
Free Radic Biol Med. 2008 Jun 1;44(11):1951-9. doi: 10.1016/j.freeradbiomed.2008.02.012. Epub 2008 Mar 8.
Macrophage NADPH oxidase activation, impaired cholesterol fluxes, and increased cholesterol biosynthesis in diabetic mice: a stimulatory role for D-glucose.
Hayek T, Kaplan M, Kerry R, Aviram M.
Atherosclerosis. 2007 Dec;195(2):277-86. Epub 2007 Jan 26.
Haptoglobin genotype is a regulator of reverse cholesterol transport in diabetes in vitro and in vivo.
Asleh R, Miller-Lotan R, Aviram M, Hayek T, Yulish M, Levy JE, Miller B, Blum S, Milman U, Shapira C, Levy AP.
Circ Res. 2006 Dec 8;99(12):1419-25. Epub 2006 Nov 2.
Atherosclerosis and the protective role played by different proteins in apolipoprotein E-deficient mice.
Fabrizio Rodella L, Bonomini F, Rezzani R, Tengattini S, Hayek T, Aviram M, Keidar S, Coleman R, Bianchi R.
Acta Histochem. 2007;109(1):45-51. Epub 2006 Oct 12.
A mouse model for human atherosclerosis: long-term histopathological study of lesion development in the aortic arch of apolipoprotein E-deficient (E0) mice.
Coleman R, Hayek T, Keidar S, Aviram M.
Acta Histochem. 2006;108(6):415-24. Epub 2006 Sep 26. Review.
Vogt-Koyanagi-Harada syndrome associated with renal failure: a case report.
Zalts R, Hayek T, Baruch Y, Nakhoul F, Miller B.
J Nephrol. 2006 Mar-Apr;19(2):225-8. Review.
Elongated eccentric soft coronary plaque: major diagnostic pitfall on quantitative coronary angiography overpowered by computed tomography coronary angiography and intravascular ultrasound.
Ghersin E, Litmanovich D, Kerner A, Engel A, Hayek T.
Australas Radiol. 2006 Jun;50(3):267-70.
Acute cytomegalovirus infection associated with the onset of inflammatory bowel disease.
Hussein K, Hayek T, Yassin K, Fischer D, Vlodavsky E, Kra-Oz Z, Hamoud S.
Am J Med Sci. 2006 Jan;331(1):40-3.
Panaortitis: diagnosis via fluorodeoxyglucose positron emission tomography.
Zalts R, Hamoud S, Bar-Shalom R, Eilam O, Rozin A, Hayek T.
Am J Med Sci. 2005 Nov;330(5):247-9.
Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages.
Rosenblat M, Hayek T, Aviram M.
Atherosclerosis. 2006 Aug;187(2):363-71. Epub 2005 Oct 13.
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