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Items: 1 to 50 of 217

1.

An innate-like Vδ1+ γδ T cell compartment in the human breast is associated with remission in triple-negative breast cancer.

Wu Y, Kyle-Cezar F, Woolf RT, Naceur-Lombardelli C, Owen J, Biswas D, Lorenc A, Vantourout P, Gazinska P, Grigoriadis A, Tutt A, Hayday A.

Sci Transl Med. 2019 Oct 9;11(513). pii: eaax9364. doi: 10.1126/scitranslmed.aax9364.

PMID:
31597756
2.

γδ T Cell Update: Adaptate Orchestrators of Immune Surveillance.

Hayday AC.

J Immunol. 2019 Jul 15;203(2):311-320. doi: 10.4049/jimmunol.1800934. Review.

PMID:
31285310
3.

Response to comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'.

Hertel C, Fishman D, Lorenc A, Ranki A, Krohn K, Peterson P, Kisand K, Hayday A.

Elife. 2019 Jun 27;8. pii: e45826. doi: 10.7554/eLife.45826.

4.

The γδTCR combines innate immunity with adaptive immunity by utilizing spatially distinct regions for agonist selection and antigen responsiveness.

Melandri D, Zlatareva I, Chaleil RAG, Dart RJ, Chancellor A, Nussbaumer O, Polyakova O, Roberts NA, Wesch D, Kabelitz D, Irving PM, John S, Mansour S, Bates PA, Vantourout P, Hayday AC.

Nat Immunol. 2018 Dec;19(12):1352-1365. doi: 10.1038/s41590-018-0253-5. Epub 2018 Nov 12.

PMID:
30420626
5.

Pillars Article: Regulation of Cutaneous Malignancy by γδ T Cells. Science. 2001. 294: 605-609.

Girardi M, Oppenheim DE, Steele CR, Lewis JM, Glusac E, Filler R, Hobby P, Sutton B, Tigelaar RE, Hayday AC.

J Immunol. 2018 May 1;200(9):3031-3035. No abstract available.

6.

Low-Density Lipoprotein Uptake Inhibits the Activation and Antitumor Functions of Human Vγ9Vδ2 T Cells.

Rodrigues NV, Correia DV, Mensurado S, Nóbrega-Pereira S, deBarros A, Kyle-Cezar F, Tutt A, Hayday AC, Norell H, Silva-Santos B, Dias S.

Cancer Immunol Res. 2018 Apr;6(4):448-457. doi: 10.1158/2326-6066.CIR-17-0327. Epub 2018 Jan 22.

7.

Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology.

Vantourout P, Laing A, Woodward MJ, Zlatareva I, Apolonia L, Jones AW, Snijders AP, Malim MH, Hayday AC.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):1039-1044. doi: 10.1073/pnas.1701237115. Epub 2018 Jan 16.

8.

High throughput automated analysis of big flow cytometry data.

Rahim A, Meskas J, Drissler S, Yue A, Lorenc A, Laing A, Saran N, White J, Abeler-Dörner L, Hayday A, Brinkman RR.

Methods. 2018 Feb 1;134-135:164-176. doi: 10.1016/j.ymeth.2017.12.015. Epub 2017 Dec 27.

9.

BTN3A1 Discriminates γδ T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain.

Salim M, Knowles TJ, Baker AT, Davey MS, Jeeves M, Sridhar P, Wilkie J, Willcox CR, Kadri H, Taher TE, Vantourout P, Hayday A, Mehellou Y, Mohammed F, Willcox BE.

ACS Chem Biol. 2017 Oct 20;12(10):2631-2643. doi: 10.1021/acschembio.7b00694. Epub 2017 Sep 14.

10.

Autoantibody Repertoire in APECED Patients Targets Two Distinct Subgroups of Proteins.

Fishman D, Kisand K, Hertel C, Rothe M, Remm A, Pihlap M, Adler P, Vilo J, Peet A, Meloni A, Podkrajsek KT, Battelino T, Bruserud Ø, Wolff ASB, Husebye ES, Kluger N, Krohn K, Ranki A, Peterson H, Hayday A, Peterson P.

Front Immunol. 2017 Aug 16;8:976. doi: 10.3389/fimmu.2017.00976. eCollection 2017.

11.

Adaptive from Innate: Human IFN-γ+CD4+ T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults.

Das A, Rouault-Pierre K, Kamdar S, Gomez-Tourino I, Wood K, Donaldson I, Mein CA, Bonnet D, Hayday AC, Gibbons DL.

J Immunol. 2017 Sep 1;199(5):1696-1705. doi: 10.4049/jimmunol.1700551. Epub 2017 Jul 28.

12.

αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis.

Lamb CA, Mansfield JC, Tew GW, Gibbons D, Long AK, Irving P, Diehl L, Eastham-Anderson J, Price MB, O'Boyle G, Jones DEJ, O'Byrne S, Hayday A, Keir ME, Egen JG, Kirby JA.

J Crohns Colitis. 2017 May 1;11(5):610-620. doi: 10.1093/ecco-jcc/jjw189.

13.

Brief Report: Blockade of TANK-Binding Kinase 1/IKKɛ Inhibits Mutant Stimulator of Interferon Genes (STING)-Mediated Inflammatory Responses in Human Peripheral Blood Mononuclear Cells.

Frémond ML, Uggenti C, Van Eyck L, Melki I, Bondet V, Kitabayashi N, Hertel C, Hayday A, Neven B, Rose Y, Duffy D, Crow YJ, Rodero MP.

Arthritis Rheumatol. 2017 Jul;69(7):1495-1501. doi: 10.1002/art.40122. Epub 2017 Jun 5.

14.

Detection of interferon alpha protein reveals differential levels and cellular sources in disease.

Rodero MP, Decalf J, Bondet V, Hunt D, Rice GI, Werneke S, McGlasson SL, Alyanakian MA, Bader-Meunier B, Barnerias C, Bellon N, Belot A, Bodemer C, Briggs TA, Desguerre I, Frémond ML, Hully M, van den Maagdenberg AMJM, Melki I, Meyts I, Musset L, Pelzer N, Quartier P, Terwindt GM, Wardlaw J, Wiseman S, Rieux-Laucat F, Rose Y, Neven B, Hertel C, Hayday A, Albert ML, Rozenberg F, Crow YJ, Duffy D.

J Exp Med. 2017 May 1;214(5):1547-1555. doi: 10.1084/jem.20161451. Epub 2017 Apr 18.

15.

Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments.

Di Marco Barros R, Roberts NA, Dart RJ, Vantourout P, Jandke A, Nussbaumer O, Deban L, Cipolat S, Hart R, Iannitto ML, Laing A, Spencer-Dene B, East P, Gibbons D, Irving PM, Pereira P, Steinhoff U, Hayday A.

Cell. 2016 Sep 22;167(1):203-218.e17. doi: 10.1016/j.cell.2016.08.030. Epub 2016 Sep 15.

16.

Secondary structure and (1)H, (13)C and (15)N resonance assignments of Skint-1: a selecting ligand for a murine γδ T cell subset implicated in tumour suppression.

Salim M, Willcox CR, Mohammed F, Hayday AC, Overduin M, Willcox BE, Knowles TJ.

Biomol NMR Assign. 2016 Oct;10(2):357-60. doi: 10.1007/s12104-016-9700-0. Epub 2016 Aug 4.

17.

AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies.

Meyer S, Woodward M, Hertel C, Vlaicu P, Haque Y, Kärner J, Macagno A, Onuoha SC, Fishman D, Peterson H, Metsküla K, Uibo R, Jäntti K, Hokynar K, Wolff ASB; APECED patient collaborative, Krohn K, Ranki A, Peterson P, Kisand K, Hayday A.

Cell. 2016 Jul 28;166(3):582-595. doi: 10.1016/j.cell.2016.06.024. Epub 2016 Jul 14.

18.

Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events.

Sobolev O, Binda E, O'Farrell S, Lorenc A, Pradines J, Huang Y, Duffner J, Schulz R, Cason J, Zambon M, Malim MH, Peakman M, Cope A, Capila I, Kaundinya GV, Hayday AC.

Nat Immunol. 2016 Apr;17(4):469. doi: 10.1038/ni0416-469b. No abstract available.

PMID:
27002849
19.

Characterization of a Putative Receptor Binding Surface on Skint-1, a Critical Determinant of Dendritic Epidermal T Cell Selection.

Salim M, Knowles TJ, Hart R, Mohammed F, Woodward MJ, Willcox CR, Overduin M, Hayday AC, Willcox BE.

J Biol Chem. 2016 Apr 22;291(17):9310-21. doi: 10.1074/jbc.M116.722066. Epub 2016 Feb 25.

20.

Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events.

Sobolev O, Binda E, O'Farrell S, Lorenc A, Pradines J, Huang Y, Duffner J, Schulz R, Cason J, Zambon M, Malim MH, Peakman M, Cope A, Capila I, Kaundinya GV, Hayday AC.

Nat Immunol. 2016 Feb;17(2):204-13. doi: 10.1038/ni.3328. Epub 2016 Jan 4. Erratum in: Nat Immunol. 2016 Apr;17(4):469.

21.

DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.

Prochazkova J, Sakaguchi S, Owusu M, Mazouzi A, Wiedner M, Velimezi G, Moder M, Turchinovich G, Hladik A, Gurnhofer E, Hayday A, Behrens A, Knapp S, Kenner L, Ellmeier W, Loizou JI.

PLoS Genet. 2015 Nov 6;11(11):e1005645. doi: 10.1371/journal.pgen.1005645. eCollection 2015 Nov.

22.

Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis.

Tew GW, Hackney JA, Gibbons D, Lamb CA, Luca D, Egen JG, Diehl L, Eastham Anderson J, Vermeire S, Mansfield JC, Feagan BG, Panes J, Baumgart DC, Schreiber S, Dotan I, Sandborn WJ, Kirby JA, Irving PM, De Hertogh G, Van Assche GA, Rutgeerts P, O'Byrne S, Hayday A, Keir ME.

Gastroenterology. 2016 Feb;150(2):477-87.e9. doi: 10.1053/j.gastro.2015.10.041. Epub 2015 Oct 30.

23.

Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance.

Swamy M, Abeler-Dörner L, Chettle J, Mahlakõiv T, Goubau D, Chakravarty P, Ramsay G, Reis E Sousa C, Staeheli P, Blacklaws BA, Heeney JL, Hayday AC.

Nat Commun. 2015 May 19;6:7090. doi: 10.1038/ncomms8090.

24.

Epigenetic and transcriptional regulation of γδ T cell differentiation: Programming cells for responses in time and space.

Schmolka N, Wencker M, Hayday AC, Silva-Santos B.

Semin Immunol. 2015 Feb;27(1):19-25. doi: 10.1016/j.smim.2015.01.001. Epub 2015 Feb 25. Review.

PMID:
25726512
25.

Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants.

Gibbons D, Fleming P, Virasami A, Michel ML, Sebire NJ, Costeloe K, Carr R, Klein N, Hayday A.

Nat Med. 2014 Oct;20(10):1206-10. doi: 10.1038/nm.3670. Epub 2014 Sep 21.

PMID:
25242415
26.

[Regulation of immunological visibility by the EGF receptor].

Vantourout P, Hayday A.

Med Sci (Paris). 2014 Aug-Sep;30(8-9):742-4. doi: 10.1051/medsci/20143008009. Epub 2014 Sep 1. French. No abstract available.

27.

IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers.

Marra P, Mathew S, Grigoriadis A, Wu Y, Kyle-Cezar F, Watkins J, Rashid M, De Rinaldis E, Hessey S, Gazinska P, Hayday A, Tutt A.

Cancer Res. 2014 Sep 1;74(17):4908-21. doi: 10.1158/0008-5472.CAN-14-0637. Epub 2014 Jun 30.

28.

Immunological visibility: posttranscriptional regulation of human NKG2D ligands by the EGF receptor pathway.

Vantourout P, Willcox C, Turner A, Swanson CM, Haque Y, Sobolev O, Grigoriadis A, Tutt A, Hayday A.

Sci Transl Med. 2014 Apr 9;6(231):231ra49. doi: 10.1126/scitranslmed.3007579.

29.

Induction of monocyte-to-dendritic cell maturation by extracorporeal photochemotherapy: initiation via direct platelet signaling.

Durazzo TS, Tigelaar RE, Filler R, Hayday A, Girardi M, Edelson RL.

Transfus Apher Sci. 2014 Jun;50(3):370-8. doi: 10.1016/j.transci.2013.11.008. Epub 2013 Nov 28.

30.

A long-playing CD about the γδ TCR repertoire.

Hayday A, Vantourout P.

Immunity. 2013 Dec 12;39(6):994-6. doi: 10.1016/j.immuni.2013.11.016.

31.

Innate-like T cells straddle innate and adaptive immunity by altering antigen-receptor responsiveness.

Wencker M, Turchinovich G, Di Marco Barros R, Deban L, Jandke A, Cope A, Hayday AC.

Nat Immunol. 2014 Jan;15(1):80-7. doi: 10.1038/ni.2773. Epub 2013 Nov 17.

32.

An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element.

Clop A, Bertoni A, Spain SL, Simpson MA, Pullabhatla V, Tonda R, Hundhausen C, Di Meglio P, De Jong P, Hayday AC, Nestle FO, Barker JN, Bell RJ, Capon F, Trembath RC.

PLoS One. 2013 Aug 19;8(8):e71690. doi: 10.1371/journal.pone.0071690. eCollection 2013.

33.

γδ T cells are essential effectors of type 1 diabetes in the nonobese diabetic mouse model.

Markle JG, Mortin-Toth S, Wong AS, Geng L, Hayday A, Danska JS.

J Immunol. 2013 Jun 1;190(11):5392-401. doi: 10.4049/jimmunol.1203502. Epub 2013 Apr 26.

34.

Six-of-the-best: unique contributions of γδ T cells to immunology.

Vantourout P, Hayday A.

Nat Rev Immunol. 2013 Feb;13(2):88-100. doi: 10.1038/nri3384. Review.

35.

Receptor for advanced glycation end products contributes to postnatal pulmonary development and adult lung maintenance program in mice.

Fineschi S, De Cunto G, Facchinetti F, Civelli M, Imbimbo BP, Carnini C, Villetti G, Lunghi B, Stochino S, Gibbons DL, Hayday A, Lungarella G, Cavarra E.

Am J Respir Cell Mol Biol. 2013 Feb;48(2):164-71. doi: 10.1165/rcmb.2012-0111OC. Epub 2012 Nov 9.

PMID:
23144333
36.

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y, Tejasvi T, Gudjonsson JE, Kang HM, Allen MH, McManus R, Novelli G, Samuelsson L, Schalkwijk J, Ståhle M, Burden AD, Smith CH, Cork MJ, Estivill X, Bowcock AM, Krueger GG, Weger W, Worthington J, Tazi-Ahnini R, Nestle FO, Hayday A, Hoffmann P, Winkelmann J, Wijmenga C, Langford C, Edkins S, Andrews R, Blackburn H, Strange A, Band G, Pearson RD, Vukcevic D, Spencer CC, Deloukas P, Mrowietz U, Schreiber S, Weidinger S, Koks S, Kingo K, Esko T, Metspalu A, Lim HW, Voorhees JJ, Weichenthal M, Wichmann HE, Chandran V, Rosen CF, Rahman P, Gladman DD, Griffiths CE, Reis A, Kere J; Collaborative Association Study of Psoriasis (CASP); Genetic Analysis of Psoriasis Consortium; Psoriasis Association Genetics Extension; Wellcome Trust Case Control Consortium 2, Nair RP, Franke A, Barker JN, Abecasis GR, Elder JT, Trembath RC.

Nat Genet. 2012 Dec;44(12):1341-8. doi: 10.1038/ng.2467. Epub 2012 Nov 11.

37.

Interleukin 7 (IL-7) selectively promotes mouse and human IL-17-producing γδ cells.

Michel ML, Pang DJ, Haque SF, Potocnik AJ, Pennington DJ, Hayday AC.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17549-54. doi: 10.1073/pnas.1204327109. Epub 2012 Oct 9.

38.

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis.

Knight J, Spain SL, Capon F, Hayday A, Nestle FO, Clop A; Wellcome Trust Case Control Consortium; Genetic Analysis of Psoriasis Consortium; I-chip for Psoriasis Consortium, Barker JN, Weale ME, Trembath RC.

Hum Mol Genet. 2012 Dec 1;21(23):5185-92. doi: 10.1093/hmg/dds344. Epub 2012 Aug 21.

39.

Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor.

Willcox CR, Pitard V, Netzer S, Couzi L, Salim M, Silberzahn T, Moreau JF, Hayday AC, Willcox BE, Déchanet-Merville J.

Nat Immunol. 2012 Sep;13(9):872-9. doi: 10.1038/ni.2394. Epub 2012 Aug 12.

PMID:
22885985
40.

NK cells promote Th-17 mediated corneal barrier disruption in dry eye.

Zhang X, Volpe EA, Gandhi NB, Schaumburg CS, Siemasko KF, Pangelinan SB, Kelly SD, Hayday AC, Li DQ, Stern ME, Niederkorn JY, Pflugfelder SC, De Paiva CS.

PLoS One. 2012;7(5):e36822. doi: 10.1371/journal.pone.0036822. Epub 2012 May 8.

41.

Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.

Roberts NA, White AJ, Jenkinson WE, Turchinovich G, Nakamura K, Withers DR, McConnell FM, Desanti GE, Benezech C, Parnell SM, Cunningham AF, Paolino M, Penninger JM, Simon AK, Nitta T, Ohigashi I, Takahama Y, Caamano JH, Hayday AC, Lane PJ, Jenkinson EJ, Anderson G.

Immunity. 2012 Mar 23;36(3):427-37. doi: 10.1016/j.immuni.2012.01.016. Epub 2012 Mar 15.

42.

Casting new light on the TCR.

Hayday A, Tigelaar R.

Nat Immunol. 2012 Feb 16;13(3):209-11. doi: 10.1038/ni.2243. No abstract available.

PMID:
22344276
43.

Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma.

Modi BG, Neustadter J, Binda E, Lewis J, Filler RB, Roberts SJ, Kwong BY, Reddy S, Overton JD, Galan A, Tigelaar R, Cai L, Fu P, Shlomchik M, Kaplan DH, Hayday A, Girardi M.

Science. 2012 Jan 6;335(6064):104-8. doi: 10.1126/science.1211600.

44.

The intraepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy.

Strid J, Sobolev O, Zafirova B, Polic B, Hayday A.

Science. 2011 Dec 2;334(6060):1293-7. doi: 10.1126/science.1211250.

45.

An NKG2D-mediated human lymphoid stress surveillance response with high interindividual variation.

Shafi S, Vantourout P, Wallace G, Antoun A, Vaughan R, Stanford M, Hayday A.

Sci Transl Med. 2011 Dec 14;3(113):113ra124. doi: 10.1126/scitranslmed.3002922. Epub 2011 Nov 30.

46.

Allele-specific cytokine responses at the HLA-C locus: implications for psoriasis.

Hundhausen C, Bertoni A, Mak RK, Botti E, Di Meglio P, Clop A, Laggner U, Chimenti S, Hayday AC, Barker JN, Trembath RC, Capon F, Nestle FO.

J Invest Dermatol. 2012 Mar;132(3 Pt 1):635-41. doi: 10.1038/jid.2011.378. Epub 2011 Nov 24.

47.

Provocative exhibits at the Seventeen Gallery.

Swamy M, Hayday A.

Nat Immunol. 2011 Nov 16;12(12):1131-3. doi: 10.1038/ni.2164. No abstract available.

PMID:
22089209
48.

Butyrophilins: an emerging family of immune regulators.

Abeler-Dörner L, Swamy M, Williams G, Hayday AC, Bas A.

Trends Immunol. 2012 Jan;33(1):34-41. doi: 10.1016/j.it.2011.09.007. Epub 2011 Oct 24. Review.

PMID:
22030238
49.

Variation of Peripheral Blood Mononuclear Cell RNA Quality in Archived Samples.

Kozlakidis Z, Mant C, Abdinur F, Cope A, Steiner S, Peakman M, Hayday A, Cason J.

Biopreserv Biobank. 2011 Sep;9(3):259-263.

50.

Identification of a novel proinflammatory human skin-homing Vγ9Vδ2 T cell subset with a potential role in psoriasis.

Laggner U, Di Meglio P, Perera GK, Hundhausen C, Lacy KE, Ali N, Smith CH, Hayday AC, Nickoloff BJ, Nestle FO.

J Immunol. 2011 Sep 1;187(5):2783-93. doi: 10.4049/jimmunol.1100804. Epub 2011 Aug 3.

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