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Items: 1 to 50 of 193

1.

The Communication Between the PI3K/AKT/mTOR Pathway and Y-box Binding Protein-1 in Gynecological Cancer.

Sobočan M, Bračič S, Knez J, Takač I, Haybaeck J.

Cancers (Basel). 2020 Jan 14;12(1). pii: E205. doi: 10.3390/cancers12010205. Review.

2.

Feedback-based Self-improving CNN Algorithm for Breast Cancer Lymph Node Metastasis Detection in Real Clinical Environment.

Sadeghi M, Maldonado I, Abele N, Haybaeck J, Boese A, Poudel P, Friebe M.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:7212-7215. doi: 10.1109/EMBC.2019.8857432.

PMID:
31947498
3.

Hepatic gene expression explains primary drug toxicity in bipolar disorder.

Birkl-Toeglhofer AM, Birkl C, Llenos IC, Weis S, Haybaeck J.

Transl Psychiatry. 2019 Dec 9;9(1):331. doi: 10.1038/s41398-019-0666-4.

4.

The Prognostic Significance of Eukaryotic Translation Initiation Factors (eIFs) in Endometrial Cancer.

Smolle MA, Czapiewski P, Lapińska-Szumczyk S, Majewska H, Supernat A, Zaczek A, Biernat W, Golob-Schwarzl N, Haybaeck J.

Int J Mol Sci. 2019 Dec 6;20(24). pii: E6169. doi: 10.3390/ijms20246169.

5.

The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma.

Kröhler T, Kessler SM, Hosseini K, List M, Barghash A, Patial S, Laggai S, Gemperlein K, Haybaeck J, Müller R, Helms V, Schulz MH, Hoppstädter J, Blackshear PJ, Kiemer AK.

Cancers (Basel). 2019 Nov 8;11(11). pii: E1754. doi: 10.3390/cancers11111754.

6.

Jak-Stat Signaling Induced by Interleukin-6 Family Cytokines in Hepatocellular Carcinoma.

Lokau J, Schoeder V, Haybaeck J, Garbers C.

Cancers (Basel). 2019 Nov 1;11(11). pii: E1704. doi: 10.3390/cancers11111704. Review.

7.

Eukaryotic translation initiation factor 6 overexpression plays a major role in the translational control of gallbladder cancer.

Golob-Schwarzl N, Wodlej C, Kleinegger F, Gogg-Kamerer M, Birkl-Toeglhofer AM, Petzold J, Aigelsreiter A, Thalhammer M, Park YN, Haybaeck J.

J Cancer Res Clin Oncol. 2019 Nov;145(11):2699-2711. doi: 10.1007/s00432-019-03030-x. Epub 2019 Oct 4.

8.

IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis.

Czepukojc B, Abuhaliema A, Barghash A, Tierling S, Naß N, Simon Y, Körbel C, Cadenas C, van Hul N, Sachinidis A, Hengstler JG, Helms V, Laschke MW, Walter J, Haybaeck J, Leclercq I, Kiemer AK, Kessler SM.

Front Med (Lausanne). 2019 Sep 4;6:179. doi: 10.3389/fmed.2019.00179. eCollection 2019.

9.

G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells.

Vo DH, Hartig R, Weinert S, Haybaeck J, Nass N.

Biomolecules. 2019 Sep 18;9(9). pii: E503. doi: 10.3390/biom9090503.

10.

Optimization of ultrastructural preservation of human brain for transmission electron microscopy after long post-mortem intervals.

Sele M, Wernitznig S, Lipovšek S, Radulović S, Haybaeck J, Birkl-Toeglhofer AM, Wodlej C, Kleinegger F, Sygulla S, Leoni M, Ropele S, Leitinger G.

Acta Neuropathol Commun. 2019 Sep 3;7(1):144. doi: 10.1186/s40478-019-0794-3.

11.

Blue Light Imaging and Linked Color Imaging for the Characterization of Mucosal Changes in Chronic Gastritis: A Clinicians View and Brief Technical Report.

Weigt J, Malfertheiner P, Canbay A, Haybaeck J, Bird-Lieberman E, Link A.

Dig Dis. 2020;38(1):9-14. doi: 10.1159/000501265. Epub 2019 Jul 23.

12.

The Insulin-Like Growth Factor 2 mRNA Binding Protein IMP2/IGF2BP2 is Overexpressed and Correlates with Poor Survival in Pancreatic Cancer.

Dahlem C, Barghash A, Puchas P, Haybaeck J, Kessler SM.

Int J Mol Sci. 2019 Jun 29;20(13). pii: E3204. doi: 10.3390/ijms20133204.

13.

Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver.

Kinast V, Leber SL, Brown RJP, Vieyres G, Behrendt P, Eßbach C, Strnad P, Vondran FWR, Cornberg M, Wex C, Pietschmann T, Haybaeck J, Todt D, Steinmann E.

Cells. 2019 Jun 18;8(6). pii: E610. doi: 10.3390/cells8060610.

14.

Clinical Impact of RANK Signalling in Ovarian Cancer.

Wieser V, Sprung S, Tsibulak I, Haybaeck J, Hackl H, Fiegl H, Marth C, Zeimet AG.

Cancers (Basel). 2019 Jun 8;11(6). pii: E791. doi: 10.3390/cancers11060791.

15.

The influence of brain iron on myelin water imaging.

Birkl C, Birkl-Toeglhofer AM, Endmayr V, Höftberger R, Kasprian G, Krebs C, Haybaeck J, Rauscher A.

Neuroimage. 2019 Oct 1;199:545-552. doi: 10.1016/j.neuroimage.2019.05.042. Epub 2019 May 17.

PMID:
31108214
16.

Diethylnitrosamine (DENA) recapitulates formation of hepatic angiosarcoma in pigs.

Kessler SM, Leber B, Hoppstädter J, Golob-Schwarzl N, Hofer EM, Schultheiss CS, Mischinger HJ, Liegl-Atzwanger B, Lackner C, Stiegler P, Haybaeck J.

PLoS One. 2019 May 16;14(5):e0214756. doi: 10.1371/journal.pone.0214756. eCollection 2019.

17.

Increasing use of immunotherapy and prolonged survival among younger patients with primary CNS lymphoma: a population-based study.

Neuhauser M, Roetzer T, Oberndorfer S, Kitzwoegerer M, Payer F, Unterluggauer JJ, Haybaeck J, Stockhammer G, Iglseder S, Moser P, Thomé C, Stultschnig M, Wuertz F, Brandner-Kokalj T, Weis S, Bandke D, Pichler J, Hutterer M, Krenosz KJ, Boehm A, Mayrbaeurl B, Hager-Seifert A, Kaufmann H, Dumser M, Reiner-Concin A, Hoenigschnabl S, Kleindienst W, Hoffermann M, Dieckmann K, Kiesel B, Widhalm G, Marosi C, Jaeger U, Hainfellner A, Hackl M, Hainfellner JA, Preusser M, Woehrer A.

Acta Oncol. 2019 Jul;58(7):967-976. doi: 10.1080/0284186X.2019.1599137. Epub 2019 Apr 17.

PMID:
30994047
18.

Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures.

Schumacher D, Andrieux G, Boehnke K, Keil M, Silvestri A, Silvestrov M, Keilholz U, Haybaeck J, Erdmann G, Sachse C, Templin M, Hoffmann J, Boerries M, Schäfer R, Regenbrecht CRA.

PLoS Genet. 2019 Mar 29;15(3):e1008076. doi: 10.1371/journal.pgen.1008076. eCollection 2019 Mar. Erratum in: PLoS Genet. 2019 May 29;15(5):e1008183.

19.

Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis.

Liao L, Schneider KM, Galvez EJC, Frissen M, Marschall HU, Su H, Hatting M, Wahlström A, Haybaeck J, Puchas P, Mohs A, Peng J, Bergheim I, Nier A, Hennings J, Reißing J, Zimmermann HW, Longerich T, Strowig T, Liedtke C, Cubero FJ, Trautwein C.

Gut. 2019 Aug;68(8):1477-1492. doi: 10.1136/gutjnl-2018-316670. Epub 2019 Mar 14.

PMID:
30872395
20.

Spinal melanotic ependymoma: A case report and review of literature.

Leber SL, Leber KA, Haybaeck J.

Pathol Res Pract. 2019 Jul;215(7):152380. doi: 10.1016/j.prp.2019.03.009. Epub 2019 Mar 4. Review.

PMID:
30871914
21.

Human melanoma brain metastases cell line MUG-Mel1, isolated clones and their detailed characterization.

Heitzer E, Groenewoud A, Meditz K, Lohberger B, Liegl-Atzwanger B, Prokesch A, Kashofer K, Behrens D, Haybaeck J, Kolb-Lenz D, Koefeler H, Riedl S, Schaider H, Fischer C, Snaar-Jagalska BE, de'Jong D, Szuhai K, Zweytick D, Rinner B.

Sci Rep. 2019 Mar 11;9(1):4096. doi: 10.1038/s41598-019-40570-1.

22.

Prognostic value of broad-spectrum keratin clones AE1/AE3 and CAM5.2 in small cell lung cancer patients undergoing pulmonary resection.

Badzio A, Czapiewski P, Gorczyński A, Szczepańska-Michalska K, Haybaeck J, Biernat W, Jassem J.

Acta Biochim Pol. 2019 Feb 22;66(1):111-114. doi: 10.18388/abp.2018_2773.

23.

Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer.

Grill M, Högenauer C, Blesl A, Haybaeck J, Golob-Schwarzl N, Ferreirós N, Thomas D, Gurke R, Trötzmüller M, Köfeler HC, Gallé B, Schicho R.

Sci Rep. 2019 Feb 20;9(1):2358. doi: 10.1038/s41598-019-38865-4.

24.

Current Coverage of the mTOR Pathway by Next-Generation Sequencing Oncology Panels.

Seeboeck R, Sarne V, Haybaeck J.

Int J Mol Sci. 2019 Feb 5;20(3). pii: E690. doi: 10.3390/ijms20030690. Review.

25.

Time resolved gene expression analysis during tamoxifen adaption of MCF-7 cells identifies long non-coding RNAs with prognostic impact.

Porsch M, Özdemir E, Wisniewski M, Graf S, Bull F, Hoffmann K, Ignatov A, Haybaeck J, Grosse I, Kalinski T, Nass N.

RNA Biol. 2019 May;16(5):661-674. doi: 10.1080/15476286.2019.1581597. Epub 2019 Mar 5.

PMID:
30760083
26.

MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors.

Schwarzenbacher D, Klec C, Pasculli B, Cerk S, Rinner B, Karbiener M, Ivan C, Barbano R, Ling H, Wulf-Goldenberg A, Stanzer S, Rinnerthaler G, Stoeger H, Bauernhofer T, Haybaeck J, Hoefler G, Jahn SW, Parrella P, Calin GA, Pichler M.

Breast Cancer Res. 2019 Feb 1;21(1):20. doi: 10.1186/s13058-019-1104-5.

27.

Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation.

Kessler SM, Hoppstädter J, Hosseini K, Laggai S, Haybaeck J, Kiemer AK.

J Hepatol. 2019 Apr;70(4):813-815. doi: 10.1016/j.jhep.2018.11.018. Epub 2019 Jan 24. No abstract available.

PMID:
30686611
28.

Melanocytes, Organogenesis, and Angiogenesis: Evidence for More than a Pigment-Producing Capability of Melanocytes.

Schatz O, Zalaudek I, Ghaffari Tabrizi-Wizsy N, Grechenig C, Grinninger P, Haas A, Haybaeck J, Hofmann-Wellenhof R, Juch H, Krassnig S, Richtig E, Lackner A, Schwab K, Wedrich A, Weger M, Schwab C.

Cells Tissues Organs. 2018;206(1-2):6-8. doi: 10.1159/000495908. Epub 2019 Jan 17. No abstract available.

PMID:
30654373
29.

Therapeutic blockade of the interleukin-6 receptor (IL-6R) allows sIL-6R generation by proteolytic cleavage.

Prenissl N, Lokau J, Rose-John S, Haybaeck J, Garbers C.

Cytokine. 2019 Feb;114:1-5. doi: 10.1016/j.cyto.2018.11.023. Epub 2018 Dec 14.

30.

Advanced microRNA-based cancer diagnostics using amplified time-gated FRET.

Qiu X, Xu J, Guo J, Yahia-Ammar A, Kapetanakis NI, Duroux-Richard I, Unterluggauer JJ, Golob-Schwarzl N, Regeard C, Uzan C, Gouy S, DuBow M, Haybaeck J, Apparailly F, Busson P, Hildebrandt N.

Chem Sci. 2018 Sep 11;9(42):8046-8055. doi: 10.1039/c8sc03121e. eCollection 2018 Nov 14.

31.

Treprostinil reduces endothelial damage in murine sinusoidal obstruction syndrome.

Themanns M, Koban F, Bergmayr C, Chrzan A, Strohmaier W, Haybaeck J, Freissmuth M, Zebedin-Brandl E.

J Mol Med (Berl). 2019 Feb;97(2):201-213. doi: 10.1007/s00109-018-1726-6. Epub 2018 Dec 7.

32.

G-protein-coupled estrogen receptor GPER-1 expression in hormone receptor-positive breast cancer is associated with poor benefit of tamoxifen.

Ignatov T, Claus M, Nass N, Haybaeck J, Seifert B, Kalinski T, Ortmann O, Ignatov A.

Breast Cancer Res Treat. 2019 Feb;174(1):121-127. doi: 10.1007/s10549-018-5064-8. Epub 2018 Nov 26.

PMID:
30478785
33.

High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype.

Golob-Schwarzl N, Bettermann K, Mehta AK, Kessler SM, Unterluggauer J, Krassnig S, Kojima K, Chen X, Hoshida Y, Bardeesy NM, Müller H, Svendova V, Schimek MG, Diwoky C, Lipfert A, Mahajan V, Stumptner C, Thüringer A, Fröhlich LF, Stojakovic T, Nilsson KPR, Kolbe T, Rülicke T, Magin TM, Strnad P, Kiemer AK, Moriggl R, Haybaeck J.

Transl Oncol. 2019 Feb;12(2):256-268. doi: 10.1016/j.tranon.2018.10.010. Epub 2018 Nov 12.

34.

Pharmacologic IL-6Rα inhibition in cholangiocarcinoma promotes cancer cell growth and survival.

Kleinegger F, Hofer E, Wodlej C, Golob-Schwarzl N, Birkl-Toeglhofer AM, Stallinger A, Petzold J, Orlova A, Krassnig S, Reihs R, Niedrist T, Mangge H, Park YN, Thalhammer M, Aigelsreiter A, Lax S, Garbers C, Fickert P, Rose-John S, Moriggl R, Rinner B, Haybaeck J.

Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1;1865(2):308-321. doi: 10.1016/j.bbadis.2018.11.006. Epub 2018 Nov 9.

35.

Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression.

Kaltenecker D, Themanns M, Mueller KM, Spirk K, Suske T, Merkel O, Kenner L, Luís A, Kozlov A, Haybaeck J, Müller M, Han X, Moriggl R.

Cytokine. 2019 Dec;124:154569. doi: 10.1016/j.cyto.2018.10.010. Epub 2018 Oct 30.

36.

STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.

Kaltenecker D, Themanns M, Mueller KM, Spirk K, Golob-Schwarzl N, Friedbichler K, Kenner L, Haybaeck J, Moriggl R.

Cytokine. 2019 Dec;124:154573. doi: 10.1016/j.cyto.2018.10.014. Epub 2018 Oct 28.

37.

Cytoplasmic location of NR4A1 in aggressive lymphomas is associated with a favourable cancer specific survival.

Fechter K, Feichtinger J, Prochazka K, Unterluggauer JJ, Pansy K, Steinbauer E, Pichler M, Haybaeck J, Prokesch A, Greinix HT, Beham-Schmid C, Neumeister P, Thallinger GG, Deutsch AJA.

Sci Rep. 2018 Sep 28;8(1):14528. doi: 10.1038/s41598-018-32972-4.

38.

Expression profile of translation initiation factor eIF2B5 in diffuse large B-cell lymphoma and its correlation to clinical outcome.

Unterluggauer JJ, Prochazka K, Tomazic PV, Huber HJ, Seeboeck R, Fechter K, Steinbauer E, Gruber V, Feichtinger J, Pichler M, Weniger MA, Küppers R, Sill H, Schicho R, Neumeister P, Beham-Schmid C, Deutsch AJA, Haybaeck J.

Blood Cancer J. 2018 Aug 22;8(9):79. doi: 10.1038/s41408-018-0112-5. No abstract available.

39.

The BRAF Status May Predict Response to Sorafenib in Gastrointestinal Stromal Tumors Resistant to Imatinib, Sunitinib, and Regorafenib: Case Series and Review of the Literature.

Franck C, Rosania R, Franke S, Haybaeck J, Canbay A, Venerito M.

Digestion. 2019;99(2):179-184. doi: 10.1159/000490886. Epub 2018 Sep 4. Review.

PMID:
30179868
40.

The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space.

Klughammer J, Kiesel B, Roetzer T, Fortelny N, Nemc A, Nenning KH, Furtner J, Sheffield NC, Datlinger P, Peter N, Nowosielski M, Augustin M, Mischkulnig M, Ströbel T, Alpar D, Ergüner B, Senekowitsch M, Moser P, Freyschlag CF, Kerschbaumer J, Thomé C, Grams AE, Stockhammer G, Kitzwoegerer M, Oberndorfer S, Marhold F, Weis S, Trenkler J, Buchroithner J, Pichler J, Haybaeck J, Krassnig S, Mahdy Ali K, von Campe G, Payer F, Sherif C, Preiser J, Hauser T, Winkler PA, Kleindienst W, Würtz F, Brandner-Kokalj T, Stultschnig M, Schweiger S, Dieckmann K, Preusser M, Langs G, Baumann B, Knosp E, Widhalm G, Marosi C, Hainfellner JA, Woehrer A, Bock C.

Nat Med. 2018 Oct;24(10):1611-1624. doi: 10.1038/s41591-018-0156-x. Epub 2018 Aug 27.

41.

Influence of eukaryotic translation initiation factor 6 on non-small cell lung cancer development and progression.

Gantenbein N, Bernhart E, Anders I, Golob-Schwarzl N, Krassnig S, Wodlej C, Brcic L, Lindenmann J, Fink-Neuboeck N, Gollowitsch F, Stacher-Priehse E, Asslaber M, Gogg-Kamerer M, Rolff J, Hoffmann J, Silvestri A, Regenbrecht C, Reinhard C, Pehserl AM, Pichler M, Sokolova O, Naumann M, Mitterer V, Pertschy B, Bergler H, Popper H, Sattler W, Haybaeck J.

Eur J Cancer. 2018 Sep;101:165-180. doi: 10.1016/j.ejca.2018.07.001. Epub 2018 Aug 1.

42.

Frequent expression of somatostatin receptor 2a in olfactory neuroblastomas: a new and distinctive feature.

Czapiewski P, Kunc M, Gorczyński A, Haybaeck J, Okoń K, Reszec J, Lewczuk A, Dzierzanowski J, Karczewska J, Biernat W, Turri-Zanoni M, Castelnuovo P, Taverna C, Franchi A, La Rosa S, Sessa F, Klöppel G.

Hum Pathol. 2018 Sep;79:144-150. doi: 10.1016/j.humpath.2018.05.013. Epub 2018 May 25.

PMID:
29807052
43.

Liver - master and servant of serum proteome.

Kuscuoglu D, Janciauskiene S, Hamesch K, Haybaeck J, Trautwein C, Strnad P.

J Hepatol. 2018 Aug;69(2):512-524. doi: 10.1016/j.jhep.2018.04.018. Epub 2018 Apr 28. Review.

PMID:
29709680
44.

Therapeutic targeting of tumor-associated macrophages in pancreatic neuroendocrine tumors.

Krug S, Abbassi R, Griesmann H, Sipos B, Wiese D, Rexin P, Blank A, Perren A, Haybaeck J, Hüttelmaier S, Rinke A, Gress TM, Michl P.

Int J Cancer. 2018 Oct 1;143(7):1806-1816. doi: 10.1002/ijc.31562.

45.

Downgrading of a G3 Neuroendocrine Tumor to a G2 Tumor: Can First-Line Cytotoxic Chemotherapy Change the Tumor Biology?

Blesl A, Krones E, Pollheimer MJ, Haybaeck J, Wiesspeiner U, Lipp RW, Kump P.

Case Rep Oncol. 2017 Dec 20;10(3):1121-1126. doi: 10.1159/000484473. eCollection 2017 Sep-Dec.

46.

Low skeletal muscle mass outperforms the Charlson Comorbidity Index in risk prediction in patients undergoing pancreatic resections.

Wagner D, Marsoner K, Tomberger A, Haybaeck J, Haas J, Werkgartner G, Cerwenka H, Bacher H, Mischinger HJ, Kornprat P.

Eur J Surg Oncol. 2018 May;44(5):658-663. doi: 10.1016/j.ejso.2018.01.095. Epub 2018 Feb 7.

PMID:
29428474
47.

Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling.

Levada K, Guldiken N, Zhang X, Vella G, Mo FR, James LP, Haybaeck J, Kessler SM, Kiemer AK, Ott T, Hartmann D, Hüser N, Ziol M, Trautwein C, Strnad P.

J Hepatol. 2018 May;68(5):996-1005. doi: 10.1016/j.jhep.2018.01.003. Epub 2018 Jan 11.

PMID:
29331340
48.

Examination of the melanocytes of the Nevus of Ota with in vivo reflectance confocal microscopy: 15 cases.

Grechenig C, Cinotti E, Labeille B, Langmann G, Perrot JL, Schatz O, Tarmann L, Wedrich A, Wackernagel W, Zalaudek I, Haybaeck J, Schwab C.

J Eur Acad Dermatol Venereol. 2018 Jun;32(6):e241-e242. doi: 10.1111/jdv.14783. Epub 2018 Mar 9. No abstract available.

PMID:
29314292
49.

Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.

Golob-Schwarzl N, Schweiger C, Koller C, Krassnig S, Gogg-Kamerer M, Gantenbein N, Toeglhofer AM, Wodlej C, Bergler H, Pertschy B, Uranitsch S, Holter M, El-Heliebi A, Fuchs J, Punschart A, Stiegler P, Keil M, Hoffmann J, Henderson D, Lehrach H, Reinhard C, Regenbrecht C, Schicho R, Fickert P, Lax S, Haybaeck J.

Oncotarget. 2017 Sep 5;8(60):101224-101243. doi: 10.18632/oncotarget.20642. eCollection 2017 Nov 24.

50.

Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells.

Regan JL, Schumacher D, Staudte S, Steffen A, Haybaeck J, Keilholz U, Schweiger C, Golob-Schwarzl N, Mumberg D, Henderson D, Lehrach H, Regenbrecht CRA, Schäfer R, Lange M.

Cell Rep. 2017 Dec 5;21(10):2813-2828. doi: 10.1016/j.celrep.2017.11.025.

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