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Items: 1 to 50 of 237

1.

Severe In-stent Calcification in a 17-year-old Bare-metal Stent.

Kudo A, Ishikawa T, Hayakawa F, Taguchi I.

Intern Med. 2019 Feb 1. doi: 10.2169/internalmedicine.2160-18. [Epub ahead of print] No abstract available.

2.

Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases.

Li JF, Dai YT, Lilljebjörn H, Shen SH, Cui BW, Bai L, Liu YF, Qian MX, Kubota Y, Kiyoi H, Matsumura I, Miyazaki Y, Olsson L, Tan AM, Ariffin H, Chen J, Takita J, Yasuda T, Mano H, Johansson B, Yang JJ, Yeoh AE, Hayakawa F, Chen Z, Pui CH, Fioretos T, Chen SJ, Huang JY.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11711-E11720. doi: 10.1073/pnas.1814397115. Epub 2018 Nov 28.

PMID:
30487223
3.

Chromosomal translocation-mediated evasion from miRNA induces strong MEF2D fusion protein expression, causing inhibition of PAX5 transcriptional activity.

Hirano D, Hayakawa F, Yasuda T, Tange N, Yamamoto H, Kojima Y, Morishita T, Imoto N, Tsuzuki S, Mano H, Naoe T, Kiyoi H.

Oncogene. 2018 Nov 26. doi: 10.1038/s41388-018-0573-9. [Epub ahead of print]

PMID:
30478446
4.

Pyruvate secreted from patient-derived cancer-associated fibroblasts supports survival of primary lymphoma cells.

Sakamoto A, Kunou S, Shimada K, Tsunoda M, Aoki T, Iriyama C, Tomita A, Nakamura S, Hayakawa F, Kiyoi H.

Cancer Sci. 2019 Jan;110(1):269-278. doi: 10.1111/cas.13873. Epub 2018 Dec 3.

5.

Biology and management of primary effusion lymphoma.

Shimada K, Hayakawa F, Kiyoi H.

Blood. 2018 Nov 1;132(18):1879-1888. doi: 10.1182/blood-2018-03-791426. Epub 2018 Aug 28. Review.

PMID:
30154110
6.

BCL2 inhibitor ABT-199 and JNK inhibitor SP600125 exhibit synergistic cytotoxicity against imatinib-resistant Ph+ ALL cells.

Inoue C, Sobue S, Aoyama Y, Mizutani N, Kawamoto Y, Nishizawa Y, Ichihara M, Abe A, Hayakawa F, Suzuki M, Nozawa Y, Murate T.

Biochem Biophys Rep. 2018 Jul 13;15:69-75. doi: 10.1016/j.bbrep.2018.07.001. eCollection 2018 Sep.

7.

Relationship between sensory analysis for texture and instrument measurements in model strawberry jam.

Kurotobi T, Hoshino T, Kazami Y, Hayakawa F, Hagura Y.

J Texture Stud. 2018 Jun 23. doi: 10.1111/jtxs.12348. [Epub ahead of print]

PMID:
29935033
8.

[Adult acute lymphoblastic leukemia: update on pathophysiology and management].

Hayakawa F.

Rinsho Ketsueki. 2018;59(5):497-503. doi: 10.11406/rinketsu.59.497. Japanese.

PMID:
29877239
9.

Transcriptional activities of DUX4 fusions in B-cell acute lymphoblastic leukemia.

Tanaka Y, Kawazu M, Yasuda T, Tamura M, Hayakawa F, Kojima S, Ueno T, Kiyoi H, Naoe T, Mano H.

Haematologica. 2018 Nov;103(11):e522-e526. doi: 10.3324/haematol.2017.183152. Epub 2018 May 17. No abstract available.

10.

Phase I study of cord blood transplantation with intrabone marrow injection of mesenchymal stem cells: A clinical study protocol.

Goto T, Murata M, Terakura S, Nishida T, Adachi Y, Ushijima Y, Shimada K, Ishikawa Y, Hayakawa F, Nishio N, Nishiwaki S, Hirakawa A, Kato K, Takahashi Y, Kiyoi H.

Medicine (Baltimore). 2018 Apr;97(17):e0449. doi: 10.1097/MD.0000000000010449.

11.

Final analysis of the JALSG Ph+ALL202 study: tyrosine kinase inhibitor-combined chemotherapy for Ph+ALL.

Hatta Y, Mizuta S, Matsuo K, Ohtake S, Iwanaga M, Sugiura I, Doki N, Kanamori H, Ueda Y, Yoshida C, Dobashi N, Maeda T, Yujiri T, Monma F, Ito Y, Hayakawa F, Takeuchi J, Kiyoi H, Miyazaki Y, Naoe T.

Ann Hematol. 2018 Sep;97(9):1535-1545. doi: 10.1007/s00277-018-3323-8. Epub 2018 Apr 24.

12.

A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells with FLT3 mutations.

Yamaura T, Nakatani T, Uda K, Ogura H, Shin W, Kurokawa N, Saito K, Fujikawa N, Date T, Takasaki M, Terada D, Hirai A, Akashi A, Chen F, Adachi Y, Ishikawa Y, Hayakawa F, Hagiwara S, Naoe T, Kiyoi H.

Blood. 2018 Jan 25;131(4):426-438. doi: 10.1182/blood-2017-05-786657. Epub 2017 Nov 29.

13.

High incidence of extensive chronic graft-versus-host disease in patients with the REG3A rs7588571 non-GG genotype.

Koyama D, Murata M, Hanajiri R, Okuno S, Kamoshita S, Julamanee J, Takagi E, Hirano D, Miyao K, Sakemura R, Goto T, Hayakawa F, Seto A, Ozawa Y, Miyamura K, Terakura S, Nishida T, Kiyoi H.

PLoS One. 2017 Sep 25;12(9):e0185213. doi: 10.1371/journal.pone.0185213. eCollection 2017.

14.

High-dose methotrexate therapy significantly improved survival of adult acute lymphoblastic leukemia: a phase III study by JALSG.

Sakura T, Hayakawa F, Sugiura I, Murayama T, Imai K, Usui N, Fujisawa S, Yamauchi T, Yujiri T, Kakihana K, Ito Y, Kanamori H, Ueda Y, Miyata Y, Kurokawa M, Asou N, Ohnishi K, Ohtake S, Kobayashi Y, Matsuo K, Kiyoi H, Miyazaki Y, Naoe T.

Leukemia. 2018 Mar;32(3):626-632. doi: 10.1038/leu.2017.283. Epub 2017 Sep 15.

PMID:
28914260
15.

Acute lymphoblastic leukemia of adolescents and young adults: from the viewpoint of physicians.

Yasuda T, Hayakawa F.

Rinsho Ketsueki. 2017;58(8):1031-1037. doi: 10.11406/rinketsu.58.1031. Japanese.

PMID:
28883266
16.

YM155 induces apoptosis through proteasome-dependent degradation of MCL-1 in primary effusion lymphoma.

Kojima Y, Hayakawa F, Morishita T, Sugimoto K, Minamikawa Y, Iwase M, Yamamoto H, Hirano D, Imoto N, Shimada K, Okada S, Kiyoi H.

Pharmacol Res. 2017 Jun;120:242-251. doi: 10.1016/j.phrs.2017.04.006. Epub 2017 Apr 8.

PMID:
28396094
17.

Malignant lymphoma with cardiac involvement.

Terakura S, Onji M, Iriyama C, Goto T, Ushijima Y, Shimada K, Ishikawa Y, Nishida T, Hayakawa F, Murata M, Kiyoi H.

Rinsho Ketsueki. 2017;58(3):239-242. doi: 10.11406/rinketsu.58.239. Japanese.

PMID:
28381692
18.

Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism.

Aoki T, Shimada K, Sakamoto A, Sugimoto K, Morishita T, Kojima Y, Shimada S, Kato S, Iriyama C, Kuno S, Harada Y, Tomita A, Hayakawa F, Kiyoi H.

Oncotarget. 2017 Feb 21;8(8):13085-13098. doi: 10.18632/oncotarget.14393.

19.

Corrigendum: Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults.

Yasuda T, Tsuzuki S, Kawazu M, Hayakawa F, Kojima S, Ueno T, Imoto N, Kohsaka S, Kunita A, Doi K, Sakura T, Yujiri T, Kondo E, Fujimaki K, Ueda Y, Aoyama Y, Ohtake S, Takita J, Sai E, Taniwaki M, Kurokawa M, Morishita S, Fukayama M, Kiyoi H, Miyazaki Y, Naoe T, Mano H.

Nat Genet. 2016 Nov 29;48(12):1591. doi: 10.1038/ng1216-1587a. No abstract available.

PMID:
27898077
20.

Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells.

Fukushima N, Minami Y, Kakiuchi S, Kuwatsuka Y, Hayakawa F, Jamieson C, Kiyoi H, Naoe T.

Cancer Sci. 2016 Oct;107(10):1422-1429. doi: 10.1111/cas.13019. Epub 2016 Sep 2.

21.

The photosensitizer verteporfin has light-independent anti-leukemic activity for Ph-positive acute lymphoblastic leukemia and synergistically works with dasatinib.

Morishita T, Hayakawa F, Sugimoto K, Iwase M, Yamamoto H, Hirano D, Kojima Y, Imoto N, Naoe T, Kiyoi H.

Oncotarget. 2016 Aug 30;7(35):56241-56252. doi: 10.18632/oncotarget.11025.

22.

Fibroblast Growth Factor-2 facilitates the growth and chemo-resistance of leukemia cells in the bone marrow by modulating osteoblast functions.

Sugimoto K, Miyata Y, Nakayama T, Saito S, Suzuki R, Hayakawa F, Nishiwaki S, Mizuno H, Takeshita K, Kato H, Ueda R, Takami A, Naoe T.

Sci Rep. 2016 Aug 2;6:30779. doi: 10.1038/srep30779.

23.

SPIB is a novel prognostic factor in diffuse large B-cell lymphoma that mediates apoptosis via the PI3K-AKT pathway.

Takagi Y, Shimada K, Shimada S, Sakamoto A, Naoe T, Nakamura S, Hayakawa F, Tomita A, Kiyoi H.

Cancer Sci. 2016 Sep;107(9):1270-80. doi: 10.1111/cas.13001. Epub 2016 Sep 6.

24.

PAX5 tyrosine phosphorylation by SYK co-operatively functions with its serine phosphorylation to cancel the PAX5-dependent repression of BLIMP1: A mechanism for antigen-triggered plasma cell differentiation.

Inagaki Y, Hayakawa F, Hirano D, Kojima Y, Morishita T, Yasuda T, Naoe T, Kiyoi H.

Biochem Biophys Res Commun. 2016 Jun 24;475(2):176-81. doi: 10.1016/j.bbrc.2016.05.067. Epub 2016 May 13.

PMID:
27181361
25.

[Adult acute lymphoblastic leukemia: current therapies and future perspectives].

Hayakawa F.

Rinsho Ketsueki. 2016 Mar;57(3):230-7. doi: 10.11406/rinketsu.57.230. Japanese.

PMID:
27076233
26.

Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults.

Yasuda T, Tsuzuki S, Kawazu M, Hayakawa F, Kojima S, Ueno T, Imoto N, Kohsaka S, Kunita A, Doi K, Sakura T, Yujiri T, Kondo E, Fujimaki K, Ueda Y, Aoyama Y, Ohtake S, Takita J, Sai E, Taniwaki M, Kurokawa M, Morishita S, Fukayama M, Kiyoi H, Miyazaki Y, Naoe T, Mano H.

Nat Genet. 2016 May;48(5):569-74. doi: 10.1038/ng.3535. Epub 2016 Mar 28. Erratum in: Nat Genet. 2016 Nov 29;48(12 ):1591.

PMID:
27019113
27.

Development and analysis of patient-derived xenograft mouse models in intravascular large B-cell lymphoma.

Shimada K, Shimada S, Sugimoto K, Nakatochi M, Suguro M, Hirakawa A, Hocking TD, Takeuchi I, Tokunaga T, Takagi Y, Sakamoto A, Aoki T, Naoe T, Nakamura S, Hayakawa F, Seto M, Tomita A, Kiyoi H.

Leukemia. 2016 Jul;30(7):1568-79. doi: 10.1038/leu.2016.67. Epub 2016 Mar 22.

PMID:
27001523
28.

Wnt signaling is associated with cell survival in the interaction between acute myeloid leukemia cells and stromal cells.

Niwa Y, Minami Y, Abe A, Hayakawa F, Yamada K, Naoe T.

Leuk Lymphoma. 2016 Sep;57(9):2192-4. doi: 10.3109/10428194.2015.1124995. Epub 2016 Jan 4. No abstract available.

PMID:
26727242
29.

B Cell Linker Protein (BLNK) Is a Selective Target of Repression by PAX5-PML Protein in the Differentiation Block That Leads to the Development of Acute Lymphoblastic Leukemia.

Imoto N, Hayakawa F, Kurahashi S, Morishita T, Kojima Y, Yasuda T, Sugimoto K, Tsuzuki S, Naoe T, Kiyoi H.

J Biol Chem. 2016 Feb 26;291(9):4723-31. doi: 10.1074/jbc.M115.637835. Epub 2015 Dec 24.

30.

A case of mucinous cystic neoplasm of the pancreas misdiagnosed as a pancreatic pseudocyst at the initial exam and resected after a 2-year follow-up.

Ishikawa T, Haruta J, Yamaguchi T, Doisaki M, Yama T, Murate K, Hattori S, Hayakawa F, Yamada K, Yashika J.

J Med Ultrason (2001). 2015 Apr;42(2):257-65. doi: 10.1007/s10396-014-0581-5. Epub 2014 Oct 8.

PMID:
26576582
31.

[Acute lymphoblastic leukemia in adolescents and young adults].

Hayakawa F.

Rinsho Ketsueki. 2015 Oct;56(10):2032-8. doi: 10.11406/rinketsu.56.2032. Review. Japanese.

PMID:
26458442
32.

Increased fetal heart rate variability in periventricular leukomalacia.

Kurahashi H, Okumura A, Kubota T, Kidokoro H, Maruyama K, Hayakawa M, Itakura A, Matsuzawa K, Yamamoto H, Kato T, Hayakawa F, Watanabe K.

Brain Dev. 2016 Feb;38(2):196-203. doi: 10.1016/j.braindev.2015.08.008. Epub 2015 Aug 31.

PMID:
26338690
33.

Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells.

Sugimoto K, Hayakawa F, Shimada S, Morishita T, Shimada K, Katakai T, Tomita A, Kiyoi H, Naoe T.

Sci Rep. 2015 Aug 17;5:13054. doi: 10.1038/srep13054.

34.

Phase I study of OPB-51602, an oral inhibitor of signal transducer and activator of transcription 3, in patients with relapsed/refractory hematological malignancies.

Ogura M, Uchida T, Terui Y, Hayakawa F, Kobayashi Y, Taniwaki M, Takamatsu Y, Naoe T, Tobinai K, Munakata W, Yamauchi T, Kageyama A, Yuasa M, Motoyama M, Tsunoda T, Hatake K.

Cancer Sci. 2015 Jul;106(7):896-901. doi: 10.1111/cas.12683. Epub 2015 May 25.

35.

Anti-cancer fatty-acid derivative induces autophagic cell death through modulation of PKM isoform expression profile mediated by bcr-abl in chronic myeloid leukemia.

Shinohara H, Taniguchi K, Kumazaki M, Yamada N, Ito Y, Otsuki Y, Uno B, Hayakawa F, Minami Y, Naoe T, Akao Y.

Cancer Lett. 2015 Apr 28;360(1):28-38. doi: 10.1016/j.canlet.2015.01.039. Epub 2015 Jan 30.

PMID:
25644089
36.

Markedly improved outcomes and acceptable toxicity in adolescents and young adults with acute lymphoblastic leukemia following treatment with a pediatric protocol: a phase II study by the Japan Adult Leukemia Study Group.

Hayakawa F, Sakura T, Yujiri T, Kondo E, Fujimaki K, Sasaki O, Miyatake J, Handa H, Ueda Y, Aoyama Y, Takada S, Tanaka Y, Usui N, Miyawaki S, Suenobu S, Horibe K, Kiyoi H, Ohnishi K, Miyazaki Y, Ohtake S, Kobayashi Y, Matsuo K, Naoe T; Japan Adult Leukemia Study Group (JALSG).

Blood Cancer J. 2014 Oct 17;4:e252. doi: 10.1038/bcj.2014.72.

37.

Development of acute pure red cell aplasia after deferasirox administration in two cases of myelodysplastic syndrome.

Hayakawa F, Tomita A, Naoe T.

Rinsho Ketsueki. 2014 Apr;55(4):445-9. Japanese.

PMID:
24850456
38.

Optimising aroma quality in curry sauce products using in vivo aroma release measurements.

Hatakeyama J, Davidson JM, Kant A, Koizumi T, Hayakawa F, Taylor AJ.

Food Chem. 2014 Aug 15;157:229-39. doi: 10.1016/j.foodchem.2014.02.034. Epub 2014 Feb 19.

PMID:
24679775
39.

GATA2 zinc finger 2 mutation found in acute myeloid leukemia impairs myeloid differentiation.

Niimi K, Kiyoi H, Ishikawa Y, Hayakawa F, Kurahashi S, Kihara R, Tomita A, Naoe T.

Leuk Res Rep. 2013 Mar 19;2(1):21-5. doi: 10.1016/j.lrr.2013.02.002. eCollection 2013.

40.

A novel STAT inhibitor, OPB-31121, has a significant antitumor effect on leukemia with STAT-addictive oncokinases.

Hayakawa F, Sugimoto K, Harada Y, Hashimoto N, Ohi N, Kurahashi S, Naoe T.

Blood Cancer J. 2013 Nov 29;3:e166. doi: 10.1038/bcj.2013.63.

41.

Characteristics of epilepsy occurring in the first four months.

Fukasawa T, Suzuki M, Kato T, Hayakawa F, Miura K, Kidokoro H, Kubota T, Okumura A, Maruyama K, Hishikawa Y, Itomi K, Negoro T, Watanabe K, Natsume J.

Brain Dev. 2014 Oct;36(9):752-7. doi: 10.1016/j.braindev.2013.10.011. Epub 2013 Nov 15.

PMID:
24246311
42.

Differences between periventricular hemorrhagic infarction and periventricular leukomalacia.

Tsuji T, Okumura A, Kidokoro H, Hayakawa F, Kubota T, Maruyama K, Kato T, Oshiro M, Hayakawa M, Watanabe K.

Brain Dev. 2014 Aug;36(7):555-62. doi: 10.1016/j.braindev.2013.07.014. Epub 2013 Aug 23.

PMID:
23978489
43.

A new electroencephalogram classification with reduced recording time in asphyxiated term infants.

Kato T, Tsuji T, Hayakawa F, Kubota T, Kidokoro H, Natsume J, Watanabe K, Okumura A.

Brain Dev. 2014 May;36(5):372-9. doi: 10.1016/j.braindev.2013.06.007. Epub 2013 Jul 5.

PMID:
23835119
44.

Superiority of experts over novices in trueness and precision of concentration estimation of sodium chloride solutions.

Masuda T, Wada Y, Okamoto M, Kyutoku Y, Yamaguchi Y, Kimura A, Kobayakawa T, Kawai T, Dan I, Hayakawa F.

Chem Senses. 2013 Mar;38(3):251-8. doi: 10.1093/chemse/bjs137. Epub 2013 Jan 10.

PMID:
23315041
45.
46.

EEG for predicting early neurodevelopment in preterm infants: an observational cohort study.

Hayashi-Kurahashi N, Kidokoro H, Kubota T, Maruyama K, Kato Y, Kato T, Natsume J, Hayakawa F, Watanabe K, Okumura A.

Pediatrics. 2012 Oct;130(4):e891-7. doi: 10.1542/peds.2012-1115. Epub 2012 Sep 3.

PMID:
22945413
47.

B cell receptor-ERK1/2 signal cancels PAX5-dependent repression of BLIMP1 through PAX5 phosphorylation: a mechanism of antigen-triggering plasma cell differentiation.

Yasuda T, Hayakawa F, Kurahashi S, Sugimoto K, Minami Y, Tomita A, Naoe T.

J Immunol. 2012 Jun 15;188(12):6127-34. doi: 10.4049/jimmunol.1103039. Epub 2012 May 16.

48.

Amplitude spectral analyses of disorganized patterns on electroencephalograms in preterm infants.

Saito M, Okumura A, Kidokoro H, Kubota T, Abe S, Ikeno M, Hayakawa F, Shimizu T, Watanabe K.

Brain Dev. 2013 Jan;35(1):38-44. doi: 10.1016/j.braindev.2012.01.011. Epub 2012 Feb 19.

PMID:
22349411
49.

Transient reduced diffusion in the cortex in a child with prolonged febrile seizures.

Kato T, Okumura A, Hayakawa F, Tsuji T, Natsume J.

Brain Dev. 2012 Oct;34(9):773-5. doi: 10.1016/j.braindev.2011.12.006. Epub 2012 Jan 10.

PMID:
22236656
50.

Amplitude-integrated electroencephalogram 1 h after birth in a preterm infant with cystic periventricular leukomalacia.

Kato T, Okumura A, Hayakawa F, Tsuji T, Hayashi S, Natsume J.

Brain Dev. 2013 Jan;35(1):75-8. doi: 10.1016/j.braindev.2011.11.010. Epub 2011 Dec 23.

PMID:
22196997

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