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A Weighted Genomic Relationship Matrix Based on Fixation Index (FST) Prioritized SNPs for Genomic Selection.

Chang LY, Toghiani S, Hay EH, Aggrey SE, Rekaya R.

Genes (Basel). 2019 Nov 12;10(11). pii: E922. doi: 10.3390/genes10110922.


Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care.

Roddy E, Clarkson K, Blagojevic-Bucknall M, Mehta R, Oppong R, Avery A, Hay EM, Heneghan C, Hartshorne L, Hooper J, Hughes G, Jowett S, Lewis M, Little P, McCartney K, Mahtani KR, Nunan D, Santer M, Williams S, Mallen CD.

Ann Rheum Dis. 2019 Oct 30. pii: annrheumdis-2019-216154. doi: 10.1136/annrheumdis-2019-216154. [Epub ahead of print]


Determining responsiveness and meaningful changes for the Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways.

Price AJ, Ogollah R, Kang S, Hay E, Barker KL, Benedetto E, Smith S, Smith J, Galloway JB, Ellis B, Rees J, Glyn-Jones S, Beard D, Fitzpatrick R, Hill JC.

BMJ Open. 2019 Oct 3;9(10):e025357. doi: 10.1136/bmjopen-2018-025357.


Early and reversible changes to the hippocampal proteome in mice on a high-fat diet.

McLean FH, Campbell FM, Sergi D, Grant C, Morris AC, Hay EA, MacKenzie A, Mayer CD, Langston RF, Williams LM.

Nutr Metab (Lond). 2019 Aug 23;16:57. doi: 10.1186/s12986-019-0387-y. eCollection 2019.


Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour.

Hay EA, McEwan A, Wilson D, Barrett P, D'Agostino G, Pertwee RG, MacKenzie A.

Psychoneuroendocrinology. 2019 Nov;109:104407. doi: 10.1016/j.psyneuen.2019.104407. Epub 2019 Aug 13.


Therapeutic effects of turmeric in several diseases: An overview.

Hay E, Lucariello A, Contieri M, Esposito T, De Luca A, Guerra G, Perna A.

Chem Biol Interact. 2019 Sep 1;310:108729. doi: 10.1016/j.cbi.2019.108729. Epub 2019 Jun 27. Review.


Metal binding and conformational studies of the calcium binding domain of NADPH oxidase 5 reveal its similarity and difference to calmodulin.

Wei CC, Fabry E, Hay E, Lloyd L, Kaufman N, Yang YP, Stuehr DJ.

J Biomol Struct Dyn. 2019 Jun 25:1-17. doi: 10.1080/07391102.2019.1633409. [Epub ahead of print]


Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study.

Protheroe J, Saunders B, Bartlam B, Dunn KM, Cooper V, Campbell P, Hill JC, Tooth S, Mallen CD, Hay EM, Foster NE.

BMC Musculoskelet Disord. 2019 Jun 1;20(1):271. doi: 10.1186/s12891-019-2587-z.


Parasitological research in the molecular age.

Selbach C, Jorge F, Dowle E, Bennett J, Chai X, Doherty JF, Eriksson A, Filion A, Hay E, Herbison R, Lindner J, Park E, Presswell B, Ruehle B, Sobrinho PM, Wainwright E, Poulin R.

Parasitology. 2019 Sep;146(11):1361-1370. doi: 10.1017/S0031182019000726. Epub 2019 Jun 18.


Multigenerational Effects.

Roberts AJ, Hay EH.

Vet Clin North Am Food Anim Pract. 2019 Jul;35(2):355-364. doi: 10.1016/j.cvfa.2019.02.009. Review.


Inflammatory biomarkers do not distinguish between patients with sciatica and referred leg pain within a primary care population: results from a nested study within the ATLAS cohort.

Hider SL, Konstantinou K, Hay EM, Glossop J, Mattey DL.

BMC Musculoskelet Disord. 2019 May 10;20(1):202. doi: 10.1186/s12891-019-2604-2.


Ecological gradients drive insect wing loss and speciation: The role of the alpine treeline.

McCulloch GA, Foster BJ, Dutoit L, Ingram T, Hay E, Veale AJ, Dearden PK, Waters JM.

Mol Ecol. 2019 Jul;28(13):3141-3150. doi: 10.1111/mec.15114. Epub 2019 May 25.


Effects of curcumin and its adjuvant on TPC1 thyroid cell line.

Esposito T, Lucariello A, Hay E, Contieri M, Tammaro P, Varriale B, Guerra G, De Luca A, Perna A.

Chem Biol Interact. 2019 May 25;305:112-118. doi: 10.1016/j.cbi.2019.03.031. Epub 2019 Mar 30.


Contribution of time of day and the circadian clock to the heat stress responsive transcriptome in Arabidopsis.

Blair EJ, Bonnot T, Hummel M, Hay E, Marzolino JM, Quijada IA, Nagel DH.

Sci Rep. 2019 Mar 18;9(1):4814. doi: 10.1038/s41598-019-41234-w.


Microcracks in subchondral bone plate is linked to less cartilage damage.

Zarka M, Hay E, Ostertag A, Marty C, Chappard C, Oudet F, Engelke K, Laredo JD, Cohen-Solal M.

Bone. 2019 Jun;123:1-7. doi: 10.1016/j.bone.2019.03.011. Epub 2019 Mar 9.


Taxonomic and geographic bias in the genetic study of helminth parasites.

Poulin R, Hay E, Jorge F.

Int J Parasitol. 2019 May;49(6):429-435. doi: 10.1016/j.ijpara.2018.12.005. Epub 2019 Feb 21.


New world goat populations are a genetically diverse reservoir for future use.

Paim TDP, Faria DA, Hay EH, McManus C, Lanari MR, Esquivel LC, Cascante MI, Alfaro EJ, Mendez A, Faco O, Silva KM, Mezzadra CA, Mariante A, Paiva SR, Blackburn HD.

Sci Rep. 2019 Feb 6;9(1):1476. doi: 10.1038/s41598-019-38812-3.


A Bayesian approach for analysis of ordered categorical responses subject to misclassification.

Ling A, Hay EH, Aggrey SE, Rekaya R.

PLoS One. 2018 Dec 13;13(12):e0208433. doi: 10.1371/journal.pone.0208433. eCollection 2018.


Performance of convolutional neural networks for identification of bacteria in 3D microscopy datasets.

Hay EA, Parthasarathy R.

PLoS Comput Biol. 2018 Dec 3;14(12):e1006628. doi: 10.1371/journal.pcbi.1006628. eCollection 2018 Dec.


Cost-utility analysis of interventions to improve effectiveness of exercise therapy for adults with knee osteoarthritis: the BEEP trial.

Kigozi J, Jowett S, Nicholls E, Tooth S, Hay EM, Foster NE; BEEP trial team.

Rheumatol Adv Pract. 2018;2(2):rky018. doi: 10.1093/rap/rky018. Epub 2018 Jun 6.


Automated high-throughput light-sheet fluorescence microscopy of larval zebrafish.

Logan SL, Dudley C, Baker RP, Taormina MJ, Hay EA, Parthasarathy R.

PLoS One. 2018 Nov 14;13(11):e0198705. doi: 10.1371/journal.pone.0198705. eCollection 2018.


The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.

Chesterton LS, Blagojevic-Bucknall M, Burton C, Dziedzic KS, Davenport G, Jowett SM, Myers HL, Oppong R, Rathod-Mistry T, van der Windt DA, Hay EM, Roddy E.

Lancet. 2018 Oct 20;392(10156):1423-1433. doi: 10.1016/S0140-6736(18)31572-1.


Inbreeding depression in line 1 Hereford cattle population using pedigree and genomic information.

Sumreddee P, Toghiani S, Hay EH, Roberts A, Agrrey SE, Rekaya R.

J Anim Sci. 2019 Jan 1;97(1):1-18. doi: 10.1093/jas/sky385.


Modernized Tools for Streamlined Genetic Manipulation and Comparative Study of Wild and Diverse Proteobacterial Lineages.

Wiles TJ, Wall ES, Schlomann BH, Hay EA, Parthasarathy R, Guillemin K.

MBio. 2018 Oct 9;9(5). pii: e01877-18. doi: 10.1128/mBio.01877-18.


Calpain-6 controls the fate of sarcoma stem cells by promoting autophagy and preventing senescence.

Andrique C, Morardet L, Linares LK, Cissé MY, Merle C, Chibon F, Provot S, Haÿ E, Ea HK, Cohen-Solal M, Modrowski D.

JCI Insight. 2018 Sep 6;3(17). pii: 121225. doi: 10.1172/jci.insight.121225. eCollection 2018 Sep 6.


Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain.

Healey EL, Afolabi EK, Lewis M, Edwards JJ, Jordan KP, Finney A, Jinks C, Hay EM, Dziedzic KS.

BMC Musculoskelet Disord. 2018 Aug 17;19(1):295. doi: 10.1186/s12891-018-2196-2.


Lessons learnt from a discontinued randomised controlled trial: adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC).

Williams NH, Jenkins A, Goulden N, Hoare Z, Hughes DA, Wood E, Foster NE, Walsh D, Carnes D, Sparkes V, Hay EM, Isaacs J, Konstantinou K, Morrissey D, Karppinen J, Genevay S, Wilkinson C.

Trials. 2018 Jul 31;19(1):408. doi: 10.1186/s13063-018-2801-6.


Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials.

Hay E, Dziedzic K, Foster N, Peat G, van der Windt D, Bartlam B, Blagojevic-Bucknall M, Edwards J, Healey E, Holden M, Hughes R, Jinks C, Jordan K, Jowett S, Lewis M, Mallen C, Morden A, Nicholls E, Ong BN, Porcheret M, Wulff J, Kigozi J, Oppong R, Paskins Z, Croft P.

Southampton (UK): NIHR Journals Library; 2018 Jul.


Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4.

Sergi D, Morris AC, Kahn DE, McLean FH, Hay EA, Kubitz P, MacKenzie A, Martinoli MG, Drew JE, Williams LM.

Nutr Neurosci. 2018 Jul 21:1-14. doi: 10.1080/1028415X.2018.1501533. [Epub ahead of print]


Correction: Osteoblastic heparan sulfate glycosaminoglycans control bone remodeling by regulating Wnt signaling and the crosstalk between bone surface and marrow cells.

Mansouri R, Jouan Y, Hay E, Blin-Wakkach C, Frain M, Ostertag A, Le Henaff C, Marty C, Geoffroy V, Marie PJ, Cohen-Solal M, Modrowski D.

Cell Death Dis. 2018 Jul 16;9(8):788. doi: 10.1038/s41419-018-0830-4.


Proprotein convertase furin inhibits matrix metalloproteinase 13 in a TGFβ-dependent manner and limits osteoarthritis in mice.

Lin H, Hay E, Latourte A, Funck-Brentano T, Bouaziz W, Ea HK, Khatib AM, Richette P, Cohen-Solal M.

Sci Rep. 2018 Jul 11;8(1):10488. doi: 10.1038/s41598-018-28713-2.


A multi-modal recruitment strategy using social media and internet-mediated methods to recruit a multidisciplinary, international sample of clinicians to an online research study.

McRobert CJ, Hill JC, Smale T, Hay EM, van der Windt DA.

PLoS One. 2018 Jul 6;13(7):e0200184. doi: 10.1371/journal.pone.0200184. eCollection 2018.


Routine micturating cystourethrogram for multicystic dysplastic kidneys: have we moved on?

Shankar S, Hay E, Ray S.

Arch Dis Child. 2018 Nov;103(11):1094-1095. doi: 10.1136/archdischild-2018-315197. Epub 2018 Jul 2. No abstract available.


Objective detection of chronic stress using physiological parameters.

Al Abdi RM, Alhitary AE, Abdul Hay EW, Al-Bashir AK.

Med Biol Eng Comput. 2018 Dec;56(12):2273-2286. doi: 10.1007/s11517-018-1854-8. Epub 2018 Jun 18.


Genomic predictions combining SNP markers and copy number variations in Nellore cattle.

Hay EHA, Utsunomiya YT, Xu L, Zhou Y, Neves HHR, Carvalheiro R, Bickhart DM, Ma L, Garcia JF, Liu GE.

BMC Genomics. 2018 Jun 5;19(1):441. doi: 10.1186/s12864-018-4787-6.


Clinical diagnostic model for sciatica developed in primary care patients with low back-related leg pain.

Stynes S, Konstantinou K, Ogollah R, Hay EM, Dunn KM.

PLoS One. 2018 Apr 5;13(4):e0191852. doi: 10.1371/journal.pone.0191852. eCollection 2018.


Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial.

Kigozi J, Jowett S, Nicholl BI, Lewis M, Bartlam B, Green D, Belcher J, Clarkson K, Lingard Z, Pope C, Chew-Graham CA, Croft P, Hay EM, Peat G, Mallen CD.

Arthritis Care Res (Hoboken). 2018 Dec;70(12):1787-1794. doi: 10.1002/acr.23568.


Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis.

Oppong R, Jowett S, Lewis M, Clarkson K, Paskins Z, Croft P, Edwards JJ, Healey E, Jordan KP, Morden A, Ong BN, Porcheret M, Finney A, Hay E, Dziedzic K.

Rheumatology (Oxford). 2018 Jun 1;57(6):1056-1063. doi: 10.1093/rheumatology/key037.


Using an internet intervention to support self-management of low back pain in primary care: findings from a randomised controlled feasibility trial (SupportBack).

Geraghty AWA, Stanford R, Stuart B, Little P, Roberts LC, Foster NE, Hill JC, Hay EM, Turner D, Malakan W, Leigh L, Yardley L.

BMJ Open. 2018 Mar 9;8(3):e016768. doi: 10.1136/bmjopen-2017-016768.


Clinical course and prognostic factors across different musculoskeletal pain sites: A secondary analysis of individual patient data from randomised clinical trials.

Green DJ, Lewis M, Mansell G, Artus M, Dziedzic KS, Hay EM, Foster NE, van der Windt DA.

Eur J Pain. 2018 Jul;22(6):1057-1070. doi: 10.1002/ejp.1190. Epub 2018 Feb 22.


Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up.

Stynes S, Konstantinou K, Ogollah R, Hay EM, Dunn KM.

Pain. 2018 Apr;159(4):728-738. doi: 10.1097/j.pain.0000000000001147.


Fast genomic prediction of breeding values using parallel Markov chain Monte Carlo with convergence diagnosis.

Guo P, Zhu B, Niu H, Wang Z, Liang Y, Chen Y, Zhang L, Ni H, Guo Y, Hay EHA, Gao X, Gao H, Wu X, Xu L, Li J.

BMC Bioinformatics. 2018 Jan 3;19(1):3. doi: 10.1186/s12859-017-2003-3.


Genomic prediction of continuous and binary fertility traits of females in a composite beef cattle breed.

Toghiani S, Hay E, Sumreddee P, Geary TW, Rekaya R, Roberts AJ.

J Anim Sci. 2017 Nov;95(11):4787-4795. doi: 10.2527/jas2017.1944.


The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol.

Healey EL, Jinks C, Foster NE, Chew-Graham CA, Pincus T, Hartshorne L, Cooke K, Nicholls E, Proctor J, Lewis M, Dent S, Wathall S, Hay EM, McBeth J.

Musculoskeletal Care. 2018 Mar;16(1):118-132. doi: 10.1002/msc.1222. Epub 2017 Dec 8.


Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort.

Konstantinou K, Dunn KM, Ogollah R, Lewis M, van der Windt D, Hay EM; ATLAS Study Team.

Spine J. 2018 Jun;18(6):1030-1040. doi: 10.1016/j.spinee.2017.10.071. Epub 2017 Nov 21.


Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica.

Williams NH, Jenkins A, Goulden N, Hoare Z, Hughes DA, Wood E, Foster NE, Walsh DA, Carnes D, Sparkes V, Hay EM, Isaacs J, Konstantinou K, Morrissey D, Karppinen J, Genevay S, Wilkinson C.

Health Technol Assess. 2017 Oct;21(60):1-180. doi: 10.3310/hta21600.


Implementing core NICE guidelines for osteoarthritis in primary care with a model consultation (MOSAICS): a cluster randomised controlled trial.

Dziedzic KS, Healey EL, Porcheret M, Afolabi EK, Lewis M, Morden A, Jinks C, McHugh GA, Ryan S, Finney A, Main C, Edwards JJ, Paskins Z, Pushpa-Rajah A, Hay EM.

Osteoarthritis Cartilage. 2018 Jan;26(1):43-53. doi: 10.1016/j.joca.2017.09.010. Epub 2017 Oct 14.


Genotype by environment interaction effects in genetic evaluation of preweaning gain for Line 1 Hereford cattle from Miles City, Montana.

MacNeil MD, Cardoso FF, Hay E.

J Anim Sci. 2017 Sep;95(9):3833-3838. doi: 10.2527/jas2017.1829.


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