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Items: 8


MMP12 preferentially attenuates axial stiffening of aging arteries.

Brankovic S, Hawthorne EA, Yu X, Zhang Y, Assoian RK.

J Biomech Eng. 2019 Mar 27. doi: 10.1115/1.4043322. [Epub ahead of print]


Cardiovascular protection in females linked to estrogen-dependent inhibition of arterial stiffening and macrophage MMP12.

Liu SL, Bajpai A, Hawthorne EA, Bae Y, Castagnino P, Monslow J, Puré E, Spiller KL, Assoian RK.

JCI Insight. 2019 Jan 10;4(1). pii: 122742. doi: 10.1172/jci.insight.122742. [Epub ahead of print]


Matrix metalloproteinase-12 is an essential mediator of acute and chronic arterial stiffening.

Liu SL, Bae YH, Yu C, Monslow J, Hawthorne EA, Castagnino P, Branchetti E, Ferrari G, Damrauer SM, Puré E, Assoian RK.

Sci Rep. 2015 Nov 26;5:17189. doi: 10.1038/srep17189.


miR-221/222 compensates for Skp2-mediated p27 degradation and is a primary target of cell cycle regulation by prostacyclin and cAMP.

Castagnino P, Kothapalli D, Hawthorne EA, Liu SL, Xu T, Rao S, Yung Y, Assoian RK.

PLoS One. 2013;8(2):e56140. doi: 10.1371/journal.pone.0056140. Epub 2013 Feb 7.


Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening.

Kothapalli D, Liu SL, Bae YH, Monslow J, Xu T, Hawthorne EA, Byfield FJ, Castagnino P, Rao S, Rader DJ, Puré E, Phillips MC, Lund-Katz S, Janmey PA, Assoian RK.

Cell Rep. 2012 Nov 29;2(5):1259-71. doi: 10.1016/j.celrep.2012.09.018. Epub 2012 Oct 25.


Cell-type- and cell-cycle-specific anti-mitogenesis by cicaprost.

Castagnino P, Kothapalli D, Hawthorne EA, Xu T, Assoian RK.

Prostaglandins Other Lipid Mediat. 2010 Sep;93(1-2):20-4. doi: 10.1016/j.prostaglandins.2010.04.004. Epub 2010 May 10.


Hyaluronan and CD44 antagonize mitogen-dependent cyclin D1 expression in mesenchymal cells.

Kothapalli D, Zhao L, Hawthorne EA, Cheng Y, Lee E, Puré E, Assoian RK.

J Cell Biol. 2007 Feb 12;176(4):535-44.


Antimitogenic effects of HDL and APOE mediated by Cox-2-dependent IP activation.

Kothapalli D, Fuki I, Ali K, Stewart SA, Zhao L, Yahil R, Kwiatkowski D, Hawthorne EA, FitzGerald GA, Phillips MC, Lund-Katz S, Puré E, Rader DJ, Assoian RK.

J Clin Invest. 2004 Feb;113(4):609-18.

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