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Items: 20

1.

Chemical synthesis and characterization of a new quinazolinedione competitive antagonist for strigolactone receptors with an unexpected binding mode.

Hamiaux C, Larsen L, Lee HW, Luo Z, Sharma P, Hawkins BC, Perry NB, Snowden KC.

Biochem J. 2019 Jun 28;476(12):1843-1856. doi: 10.1042/BCJ20190288.

PMID:
31186286
2.

Benzannulated 6,5-Spiroketals from Donor-Acceptor Cyclopropanes.

Gai S, Lucas NT, Hawkins BC.

Org Lett. 2019 Apr 19;21(8):2872-2875. doi: 10.1021/acs.orglett.9b00878. Epub 2019 Mar 29.

PMID:
30924665
3.

Selective Mono-allylation of 1,3-Diketones and Their Use in the Synthesis of 3-Allyl Chromones and Benzannulated 6,5-Bicyclic Ketals.

Swaney BE, Gai S, Clark MR, Hawkins BC.

Chem Asian J. 2019 Apr 15;14(8):1102-1105. doi: 10.1002/asia.201801695. Epub 2018 Dec 28.

PMID:
30552751
4.

Strategies, Setbacks, and Successes in the Synthesis of (-)-Spiroleucettadine.

Lamb RA, Lucas NT, Lessene G, Hawkins BC.

J Org Chem. 2018 Sep 7;83(17):10120-10133. doi: 10.1021/acs.joc.8b01404. Epub 2018 Jul 26.

PMID:
30003773
5.

Anticancer potential of novel curcumin analogs towards castrate-resistant prostate cancer.

Chen S, Nimick M, Cridge AG, Hawkins BC, Rosengren RJ.

Int J Oncol. 2018 Feb;52(2):579-588. doi: 10.3892/ijo.2017.4207. Epub 2017 Nov 20.

PMID:
29207190
6.

Total Synthesis of (-)-Spiroleucettadine.

Lamb RA, Aberle NS, Lucas NT, Lessene G, Hawkins BC.

Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14663-14666. doi: 10.1002/anie.201708110. Epub 2017 Oct 20.

PMID:
28960638
7.

Synthesis of Chromones from 1,1-Diacylcyclopropanes: Toward the Synthesis of Bromophycoic Acid E.

Smith RJ, Nhu D, Clark MR, Gai S, Lucas NT, Hawkins BC.

J Org Chem. 2017 May 19;82(10):5317-5327. doi: 10.1021/acs.joc.7b00648. Epub 2017 May 4.

PMID:
28440639
8.

Curcumin and its cyclohexanone analogue inhibited human Equilibrative nucleoside transporter 1 (ENT1) in pancreatic cancer cells.

Revalde JL, Li Y, Wijeratne TS, Bugde P, Hawkins BC, Rosengren RJ, Paxton JW.

Eur J Pharmacol. 2017 May 15;803:167-173. doi: 10.1016/j.ejphar.2017.03.055. Epub 2017 Mar 29.

PMID:
28365185
9.

Flavone C-glycosides from Trichuriella monsoniae (L.f.) Bennet.

Chiluka R, Gamble AB, Lucas NT, Hawkins BC, Bhumkar A, Achanta PS, Bobbala RK.

Nat Prod Res. 2016 Oct;30(19):2235-7. doi: 10.1080/14786419.2016.1149707. Epub 2016 Mar 8.

PMID:
26956555
10.

The Synthesis of Multifunctionalized 1,3-Oxazin-4-ones from Donor-Acceptor Cyclopropanes.

Smith RJ, Mills DA, Nhu D, Tan EW, Lucas NT, Hawkins BC.

J Org Chem. 2016 Mar 4;81(5):2099-105. doi: 10.1021/acs.joc.6b00112. Epub 2016 Feb 22.

PMID:
26867102
11.

Cytotoxic Amides from Fruits of Kawakawa, Macropiper excelsum.

Lei J, Burgess EJ, Richardson AT, Hawkins BC, Baird SK, Smallfield BM, van Klink JW, Perry NB.

Planta Med. 2015 Aug;81(12-13):1163-8. doi: 10.1055/s-0035-1546106. Epub 2015 Jun 3.

PMID:
26039266
12.

Heterocyclic cyclohexanone monocarbonyl analogs of curcumin can inhibit the activity of ATP-binding cassette transporters in cancer multidrug resistance.

Revalde JL, Li Y, Hawkins BC, Rosengren RJ, Paxton JW.

Biochem Pharmacol. 2015 Feb 1;93(3):305-17. doi: 10.1016/j.bcp.2014.12.012. Epub 2014 Dec 25.

PMID:
25543853
13.

Expedient metal-free synthesis of 1,3-oxazinen-4-ones.

Craig AJ, van der Salm L, Stevens-Cullinane L, Lucas NT, Tan EW, Hawkins BC.

Org Lett. 2015 Jan 16;17(2):234-7. doi: 10.1021/ol503350h. Epub 2014 Dec 24.

PMID:
25537108
14.

Simplified silvestrol analogues with potent cytotoxic activity.

Hawkins BC, Lindqvist LM, Nhu D, Sharp PP, Segal D, Powell AK, Campbell M, Ryan E, Chambers JM, White JM, Rizzacasa MA, Lessene G, Huang DC, Burns CJ.

ChemMedChem. 2014 Jul;9(7):1556-66. doi: 10.1002/cmdc.201400024. Epub 2014 Mar 27.

PMID:
24677741
15.

Total synthesis of the proposed structure of 8-deshydroxyajudazol A: a modified approach to 2,4-disubstituted oxazoles.

Birkett S, Ganame D, Hawkins BC, Meiries S, Quach T, Rizzacasa MA.

J Org Chem. 2013 Jan 4;78(1):116-23. doi: 10.1021/jo302055w. Epub 2012 Nov 14.

PMID:
23126596
16.

Total synthesis of 8-deshydroxyajudazol B.

Birkett S, Ganame D, Hawkins BC, Meiries S, Quach T, Rizzacasa MA.

Org Lett. 2011 Apr 15;13(8):1964-7. doi: 10.1021/ol200331u. Epub 2011 Mar 16.

PMID:
21410165
17.

Total synthesis of the potent anticancer Aglaia metabolites (-)-silvestrol and (-)-episilvestrol and the active analogue (-)-4'-desmethoxyepisilvestrol.

Adams TE, El Sous M, Hawkins BC, Hirner S, Holloway G, Khoo ML, Owen DJ, Savage GP, Scammells PJ, Rizzacasa MA.

J Am Chem Soc. 2009 Feb 4;131(4):1607-16. doi: 10.1021/ja808402e.

PMID:
19140688
18.

A mild and general method for the synthesis of 5-substituted and 5,5-disubstituted fulleroprolines.

Thayumanavan R, Hawkins BC, Keller PA, Pyne SG, Ball GE.

Org Lett. 2008 Mar 20;10(6):1315-7. doi: 10.1021/ol8002157. Epub 2008 Feb 21.

PMID:
18288860
19.

Structural reassignment of the mono- and bis-addition products from the addition reactions of N-(Diphenylmethylene)glycinate esters to [60]fullerene under Bingel conditions.

Ball GE, Burley GA, Chaker L, Hawkins BC, Williams JR, Keller PA, Pyne SG.

J Org Chem. 2005 Oct 14;70(21):8572-4.

PMID:
16209611
20.

Comparative pharmacokinetics of temazepam Gelthix and liquid-filled soft gelatin capsules.

Drake J, Freedman PS, Hawkins BC, Horth CE, Launchbury AP, Whateley-Smith C.

J Clin Pharm Ther. 1991 Oct;16(5):345-51.

PMID:
1752914

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