Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 132

1.

Bone secreted factors induce cellular quiescence in prostate cancer cells.

Yu-Lee LY, Lee YC, Pan J, Lin SC, Pan T, Yu G, Hawke DH, Pan BF, Lin SH.

Sci Rep. 2019 Dec 9;9(1):18635. doi: 10.1038/s41598-019-54566-4.

PMID:
31819067
2.

Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.

Hu Q, Ye Y, Chan LC, Li Y, Liang K, Lin A, Egranov SD, Zhang Y, Xia W, Gong J, Pan Y, Chatterjee SS, Yao J, Evans KW, Nguyen TK, Park PK, Liu J, Coarfa C, Donepudi SR, Putluri V, Putluri N, Sreekumar A, Ambati CR, Hawke DH, Marks JR, Gunaratne PH, Caudle AS, Sahin AA, Hortobagyi GN, Meric-Bernstam F, Chen L, Yu D, Hung MC, Curran MA, Han L, Lin C, Yang L.

Nat Immunol. 2019 Jul;20(7):835-851. doi: 10.1038/s41590-019-0400-7. Epub 2019 Jun 3.

3.

Mistletoe extract Fraxini inhibits the proliferation of liver cancer by down-regulating c-Myc expression.

Yang P, Jiang Y, Pan Y, Ding X, Rhea P, Ding J, Hawke DH, Felsher D, Narla G, Lu Z, Lee RT.

Sci Rep. 2019 Apr 23;9(1):6428. doi: 10.1038/s41598-019-41444-2.

4.

PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease.

Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, Nguyen TK, Park PK, Egranov SD, Ambati CR, Putluri N, Hawke DH, Han L, Hung MC, Danesh FR, Yang L, Lin C.

J Clin Invest. 2019 Mar 1;129(3):1129-1151. doi: 10.1172/JCI121987. Epub 2019 Feb 11.

5.

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

Hu Q, Li C, Wang S, Li Y, Wen B, Zhang Y, Liang K, Yao J, Ye Y, Hsiao H, Nguyen TK, Park PK, Egranov SD, Hawke DH, Marks JR, Han L, Hung MC, Zhang B, Lin C, Yang L.

Cell Res. 2019 Apr;29(4):286-304. doi: 10.1038/s41422-018-0134-3. Epub 2019 Jan 10.

PMID:
30631154
6.

Eating at high elevation: an herbivorous beetle from alpine rock outcrops relies on ammonia-absorbing lichens.

Marris J, Hawke D, Glenny D.

Ecology. 2019 May;100(5):e02598. doi: 10.1002/ecy.2598. Epub 2019 Feb 28. No abstract available.

PMID:
30620057
7.

Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface.

Galloway-Peña J, DebRoy S, Brumlow C, Li X, Tran TT, Horstmann N, Yao H, Chen K, Wang F, Pan BF, Hawke DH, Thompson EJ, Arias CA, Fowler VG Jr, Bhatti MM, Kalia A, Flores AR, Shelburne SA.

PLoS One. 2018 Dec 5;13(12):e0207897. doi: 10.1371/journal.pone.0207897. eCollection 2018.

8.

Isotopic evidence for oligotrophication of terrestrial ecosystems.

Craine JM, Elmore AJ, Wang L, Aranibar J, Bauters M, Boeckx P, Crowley BE, Dawes MA, Delzon S, Fajardo A, Fang Y, Fujiyoshi L, Gray A, Guerrieri R, Gundale MJ, Hawke DJ, Hietz P, Jonard M, Kearsley E, Kenzo T, Makarov M, Marañón-Jiménez S, McGlynn TP, McNeil BE, Mosher SG, Nelson DM, Peri PL, Roggy JC, Sanders-DeMott R, Song M, Szpak P, Templer PH, Van der Colff D, Werner C, Xu X, Yang Y, Yu G, Zmudczyńska-Skarbek K.

Nat Ecol Evol. 2018 Nov;2(11):1735-1744. doi: 10.1038/s41559-018-0694-0. Epub 2018 Oct 22.

PMID:
30349095
9.

Expression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer.

Xing Z, Zhang Y, Liang K, Yan L, Xiang Y, Li C, Hu Q, Jin F, Putluri V, Putluri N, Coarfa C, Sreekumar A, Park PK, Nguyen TK, Wang S, Zhou J, Zhou Y, Marks JR, Hawke DH, Hung MC, Yang L, Han L, Ying H, Lin C.

Cancer Res. 2018 Aug 15;78(16):4524-4532. doi: 10.1158/0008-5472.CAN-17-0385. Epub 2018 Jul 2.

10.

A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer.

Peng X, Xu X, Wang Y, Hawke DH, Yu S, Han L, Zhou Z, Mojumdar K, Jeong KJ, Labrie M, Tsang YH, Zhang M, Lu Y, Hwu P, Scott KL, Liang H, Mills GB.

Cancer Cell. 2018 May 14;33(5):817-828.e7. doi: 10.1016/j.ccell.2018.03.026. Epub 2018 Apr 26.

11.

Peptide Vaccine Formulation Controls the Duration of Antigen Presentation and Magnitude of Tumor-Specific CD8+ T Cell Response.

Khong H, Volmari A, Sharma M, Dai Z, Imo CS, Hailemichael Y, Singh M, Moore DT, Xiao Z, Huang XF, Horvath TD, Hawke DH, Overwijk WW.

J Immunol. 2018 May 15;200(10):3464-3474. doi: 10.4049/jimmunol.1700467. Epub 2018 Apr 11.

12.

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes.

Gabrusiewicz K, Li X, Wei J, Hashimoto Y, Marisetty AL, Ott M, Wang F, Hawke D, Yu J, Healy LM, Hossain A, Akers JC, Maiti SN, Yamashita S, Shimizu Y, Dunner K, Zal MA, Burks JK, Gumin J, Nwajei F, Rezavanian A, Zhou S, Rao G, Sawaya R, Fuller GN, Huse JT, Antel JP, Li S, Cooper L, Sulman EP, Chen C, Geula C, Kalluri R, Zal T, Heimberger AB.

Oncoimmunology. 2018 Jan 16;7(4):e1412909. doi: 10.1080/2162402X.2017.1412909. eCollection 2018.

13.

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase.

Wang Y, Guo YR, Liu K, Yin Z, Liu R, Xia Y, Tan L, Yang P, Lee JH, Li XJ, Hawke D, Zheng Y, Qian X, Lyu J, He J, Xing D, Tao YJ, Lu Z.

Nature. 2017 Dec 14;552(7684):273-277. doi: 10.1038/nature25003. Epub 2017 Dec 6.

14.

Genome-wide identification and differential analysis of translational initiation.

Zhang P, He D, Xu Y, Hou J, Pan BF, Wang Y, Liu T, Davis CM, Ehli EA, Tan L, Zhou F, Hu J, Yu Y, Chen X, Nguyen TM, Rosen JM, Hawke DH, Ji Z, Chen Y.

Nat Commun. 2017 Nov 23;8(1):1749. doi: 10.1038/s41467-017-01981-8.

15.

A Pan-cancer Analysis of the Expression and Clinical Relevance of Small Nucleolar RNAs in Human Cancer.

Gong J, Li Y, Liu CJ, Xiang Y, Li C, Ye Y, Zhang Z, Hawke DH, Park PK, Diao L, Putkey JA, Yang L, Guo AY, Lin C, Han L.

Cell Rep. 2017 Nov 14;21(7):1968-1981. doi: 10.1016/j.celrep.2017.10.070.

16.

JAK2-binding long noncoding RNA promotes breast cancer brain metastasis.

Wang S, Liang K, Hu Q, Li P, Song J, Yang Y, Yao J, Mangala LS, Li C, Yang W, Park PK, Hawke DH, Zhou J, Zhou Y, Xia W, Hung MC, Marks JR, Gallick GE, Lopez-Berestein G, Flores ER, Sood AK, Huang S, Yu D, Yang L, Lin C.

J Clin Invest. 2017 Dec 1;127(12):4498-4515. doi: 10.1172/JCI91553. Epub 2017 Nov 13.

17.

Positional stable isotope tracer analysis reveals carbon routes during ammonia metabolism of Aedes aegypti mosquitoes.

Horvath TD, Dagan S, Lorenzi PL, Hawke DH, Scaraffia PY.

FASEB J. 2018 Jan;32(1):466-477. doi: 10.1096/fj.201700657R. Epub 2017 Sep 25.

18.

Beyond COX-1: the effects of aspirin on platelet biology and potential mechanisms of chemoprevention.

Ornelas A, Zacharias-Millward N, Menter DG, Davis JS, Lichtenberger L, Hawke D, Hawk E, Vilar E, Bhattacharya P, Millward S.

Cancer Metastasis Rev. 2017 Jun;36(2):289-303. doi: 10.1007/s10555-017-9675-z. Review.

19.

Proteomics Profiling of Exosomes from Primary Mouse Osteoblasts under Proliferation versus Mineralization Conditions and Characterization of Their Uptake into Prostate Cancer Cells.

Bilen MA, Pan T, Lee YC, Lin SC, Yu G, Pan J, Hawke D, Pan BF, Vykoukal J, Gray K, Satcher RL, Gallick GE, Yu-Lee LY, Lin SH.

J Proteome Res. 2017 Aug 4;16(8):2709-2728. doi: 10.1021/acs.jproteome.6b00981. Epub 2017 Jul 18.

20.

SLC45A2: A Melanoma Antigen with High Tumor Selectivity and Reduced Potential for Autoimmune Toxicity.

Park J, Talukder AH, Lim SA, Kim K, Pan K, Melendez B, Bradley SD, Jackson KR, Khalili JS, Wang J, Creasy C, Pan BF, Woodman SE, Bernatchez C, Hawke D, Hwu P, Lee KM, Roszik J, Lizée G, Yee C.

Cancer Immunol Res. 2017 Aug;5(8):618-629. doi: 10.1158/2326-6066.CIR-17-0051. Epub 2017 Jun 19.

21.

Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy.

Qian X, Li X, Cai Q, Zhang C, Yu Q, Jiang Y, Lee JH, Hawke D, Wang Y, Xia Y, Zheng Y, Jiang BH, Liu DX, Jiang T, Lu Z.

Mol Cell. 2017 Mar 2;65(5):917-931.e6. doi: 10.1016/j.molcel.2017.01.027. Epub 2017 Feb 23.

22.

The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors.

Lin A, Hu Q, Li C, Xing Z, Ma G, Wang C, Li J, Ye Y, Yao J, Liang K, Wang S, Park PK, Marks JR, Zhou Y, Zhou J, Hung MC, Liang H, Hu Z, Shen H, Hawke DH, Han L, Zhou Y, Lin C, Yang L.

Nat Cell Biol. 2017 Mar;19(3):238-251. doi: 10.1038/ncb3473. Epub 2017 Feb 20.

23.

A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis.

Li C, Wang S, Xing Z, Lin A, Liang K, Song J, Hu Q, Yao J, Chen Z, Park PK, Hawke DH, Zhou J, Zhou Y, Zhang S, Liang H, Hung MC, Gallick GE, Han L, Lin C, Yang L.

Nat Cell Biol. 2017 Feb;19(2):106-119. doi: 10.1038/ncb3464. Epub 2017 Jan 23.

24.

Argininosuccinate synthetase 1 (ASS1) is a common metabolic marker of chemosensitivity for targeted arginine- and glutamine-starvation therapy.

Long Y, Tsai WB, Wang D, Hawke DH, Savaraj N, Feun LG, Hung MC, Chen HH, Kuo MT.

Cancer Lett. 2017 Mar 1;388:54-63. doi: 10.1016/j.canlet.2016.11.028. Epub 2016 Nov 30.

PMID:
27913198
25.

Minimal ecosystem uptake of selenium from Westland petrels, a forest-breeding seabird.

Hawke DJ, Gamlen-Greene R, Harding JS, Leishman D.

Sci Total Environ. 2017 Jan 1;574:148-154. doi: 10.1016/j.scitotenv.2016.08.203. Epub 2016 Sep 12.

PMID:
27627690
26.

Cathepsin G is broadly expressed in acute myeloid leukemia and is an effective immunotherapeutic target.

Alatrash G, Garber HR, Zhang M, Sukhumalchandra P, Qiu Y, Jakher H, Perakis AA, Becker L, Yoo SY, Dwyer KC, Coombes K, Talukder AH, John LSS, Senyukov V, Lee DA, Sergeeva A, He H, Ma Q, Armistead PM, Roszik J, Mittendorf EA, Molldrem JJ, Hawke D, Lizee G, Kornblau SM.

Leukemia. 2017 Jan;31(1):234-237. doi: 10.1038/leu.2016.249. Epub 2016 Aug 30. No abstract available.

27.

Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex.

Sasai K, Katayama H, Hawke DH, Sen S.

PLoS One. 2016 Jun 22;11(6):e0157305. doi: 10.1371/journal.pone.0157305. eCollection 2016.

28.

Corrigendum: A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation.

Li X, Qian X, Peng LX, Jiang Y, Hawke DH, Zheng Y, Xia Y, Lee JH, Cote G, Wang H, Wang L, Qian CN, Lu Z.

Nat Cell Biol. 2016 May 27;18(6):709. doi: 10.1038/ncb3361. No abstract available.

PMID:
27230532
29.

A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation.

Li X, Qian X, Peng LX, Jiang Y, Hawke DH, Zheng Y, Xia Y, Lee JH, Cote G, Wang H, Wang L, Qian CN, Lu Z.

Nat Cell Biol. 2016 May;18(5):561-71. doi: 10.1038/ncb3338. Epub 2016 Apr 18. Erratum in: Nat Cell Biol. 2016 May 27;18(6):709.

30.

Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis.

Li X, Jiang Y, Meisenhelder J, Yang W, Hawke DH, Zheng Y, Xia Y, Aldape K, He J, Hunter T, Wang L, Lu Z.

Mol Cell. 2016 Mar 3;61(5):705-719. doi: 10.1016/j.molcel.2016.02.009.

31.

Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1.

Singhmar P, Huo X, Eijkelkamp N, Berciano SR, Baameur F, Mei FC, Zhu Y, Cheng X, Hawke D, Mayor F Jr, Murga C, Heijnen CJ, Kavelaars A.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3036-41. doi: 10.1073/pnas.1516036113. Epub 2016 Feb 29.

32.

The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer.

Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, Wang C, Hawke DH, Wang S, Zhang Y, Wei Y, Ma G, Park PK, Zhou J, Zhou Y, Hu Z, Zhou Y, Marks JR, Liang H, Hung MC, Lin C, Yang L.

Nat Cell Biol. 2016 Feb;18(2):213-24. doi: 10.1038/ncb3295. Epub 2016 Jan 11.

33.

Phosphopeptide Enrichment by Covalent Chromatography After Solid Phase Derivatization of Protein Digests on Reversed Phase Supports.

Nika H, Angeletti RH, Hawke DH.

Methods Mol Biol. 2016;1355:31-50. doi: 10.1007/978-1-4939-3049-4_3.

PMID:
26584917
34.

Identification of Bone-Derived Factors Conferring De Novo Therapeutic Resistance in Metastatic Prostate Cancer.

Lee YC, Lin SC, Yu G, Cheng CJ, Liu B, Liu HC, Hawke DH, Parikh NU, Varkaris A, Corn P, Logothetis C, Satcher RL, Yu-Lee LY, Gallick GE, Lin SH.

Cancer Res. 2015 Nov 15;75(22):4949-59. doi: 10.1158/0008-5472.CAN-15-1215. Epub 2015 Nov 3.

35.

Secreted and O-GlcNAcylated MIF binds to the human EGF receptor and inhibits its activation.

Zheng Y, Li X, Qian X, Wang Y, Lee JH, Xia Y, Hawke DH, Zhang G, Lyu J, Lu Z.

Nat Cell Biol. 2015 Oct;17(10):1348-55. doi: 10.1038/ncb3222. Epub 2015 Aug 17.

36.

Regulation of the PI3K pathway through a p85α monomer-homodimer equilibrium.

Cheung LW, Walkiewicz KW, Besong TM, Guo H, Hawke DH, Arold ST, Mills GB.

Elife. 2015 Jul 29;4:e06866. doi: 10.7554/eLife.06866.

37.

XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A.

Miyake T, Pradeep S, Wu SY, Rupaimoole R, Zand B, Wen Y, Gharpure KM, Nagaraja AS, Hu W, Cho MS, Dalton HJ, Previs RA, Taylor ML, Hisamatsu T, Kang Y, Liu T, Shacham S, McCauley D, Hawke DH, Wiktorowicz JE, Coleman RL, Sood AK.

Clin Cancer Res. 2015 Jul 15;21(14):3286-97. doi: 10.1158/1078-0432.CCR-14-1953. Epub 2015 Apr 15.

38.

Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study.

Pasqualini R, Millikan RE, Christianson DR, Cardó-Vila M, Driessen WH, Giordano RJ, Hajitou A, Hoang AG, Wen S, Barnhart KF, Baze WB, Marcott VD, Hawke DH, Do KA, Navone NM, Efstathiou E, Troncoso P, Lobb RR, Logothetis CJ, Arap W.

Cancer. 2015 Jul 15;121(14):2411-21. doi: 10.1002/cncr.29344. Epub 2015 Apr 1.

39.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

Li X, Wang W, Wang J, Malovannaya A, Xi Y, Li W, Guerra R, Hawke DH, Qin J, Chen J.

Mol Syst Biol. 2015 Jan 21;11(1):775. doi: 10.15252/msb.20145504.

40.

Benchtop isolation and characterization of functional exosomes by sequential filtration.

Heinemann ML, Ilmer M, Silva LP, Hawke DH, Recio A, Vorontsova MA, Alt E, Vykoukal J.

J Chromatogr A. 2014 Dec 5;1371:125-35.

PMID:
25458527
41.

lncRNA directs cooperative epigenetic regulation downstream of chemokine signals.

Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, Park PK, Qin L, Wei Y, Hawke DH, Hung MC, Lin C, Yang L.

Cell. 2014 Nov 20;159(5):1110-1125. doi: 10.1016/j.cell.2014.10.013. Epub 2014 Nov 13.

42.

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

Jiang Y, Wang Y, Wang T, Hawke DH, Zheng Y, Li X, Zhou Q, Majumder S, Bi E, Liu DX, Huang S, Lu Z.

Nat Commun. 2014 Nov 21;5:5566. doi: 10.1038/ncomms6566.

43.

Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors.

Cheung LW, Yu S, Zhang D, Li J, Ng PK, Panupinthu N, Mitra S, Ju Z, Yu Q, Liang H, Hawke DH, Lu Y, Broaddus RR, Mills GB.

Cancer Cell. 2014 Oct 13;26(4):479-94. doi: 10.1016/j.ccell.2014.08.017. Epub 2014 Oct 2.

44.

N-terminal protein characterization by mass spectrometry using combined microscale liquid and solid-phase derivatization.

Nika H, Angeletti RH, Hawke DH.

J Biomol Tech. 2014 Sep;25(3):77-86. doi: 10.7171/jbt.14-2503-001.

45.

Targeted metabolomic analysis of amino acid response to L-asparaginase in adherent cells.

Purwaha P, Lorenzi PL, Silva LP, Hawke DH, Weinstein JN.

Metabolomics. 2014;10(5):909-919. Epub 2014 Feb 7.

46.

PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis.

Yang W, Xia Y, Hawke D, Li X, Liang J, Xing D, Aldape K, Hunter T, Yung WKA, Lu Z.

Cell. 2014 Aug 28;158(5):1210. doi: 10.1016/j.cell.2014.08.003. Epub 2014 Aug 28. No abstract available.

47.

An artifact in LC-MS/MS measurement of glutamine and glutamic acid: in-source cyclization to pyroglutamic acid.

Purwaha P, Silva LP, Hawke DH, Weinstein JN, Lorenzi PL.

Anal Chem. 2014 Jun 17;86(12):5633-7. doi: 10.1021/ac501451v. Epub 2014 Jun 5.

48.
49.

C-terminal protein characterization by mass spectrometry: isolation of C-terminal fragments from cyanogen bromide-cleaved protein.

Nika H, Hawke DH, Angeletti RH.

J Biomol Tech. 2014 Apr;25(1):1-18. doi: 10.7171/jbt.14-2501-001.

50.

Molecular characterization of exosome-like vesicles from breast cancer cells.

Kruger S, Abd Elmageed ZY, Hawke DH, Wörner PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R.

BMC Cancer. 2014 Jan 27;14:44. doi: 10.1186/1471-2407-14-44.

Supplemental Content

Support Center