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Items: 21


Natural and Induced Tolerogenic Dendritic Cells.

Iberg CA, Hawiger D.

J Immunol. 2020 Feb 15;204(4):733-744. doi: 10.4049/jimmunol.1901121. Review.


Advancing immunomodulation by in vivo antigen delivery to DEC-205 and other cell surface molecules using recombinant chimeric antibodies.

Iberg CA, Hawiger D.

Int Immunopharmacol. 2019 Aug;73:575-580. doi: 10.1016/j.intimp.2019.05.037. Epub 2019 Jun 19. Review.


The BTLA-HVEM-CD5 Immunoregulatory Axis-An Instructive Mechanism Governing pTreg Cell Differentiation.

Bourque J, Hawiger D.

Front Immunol. 2019 May 22;10:1163. doi: 10.3389/fimmu.2019.01163. eCollection 2019. No abstract available.


Immunomodulatory Bonds of the Partnership between Dendritic Cells and T Cells.

Bourque J, Hawiger D.

Crit Rev Immunol. 2018;38(5):379-401. doi: 10.1615/CritRevImmunol.2018026790. Review.


Dendritic Cells As Inducers of Peripheral Tolerance.

Iberg CA, Jones A, Hawiger D.

Trends Immunol. 2017 Nov;38(11):793-804. doi: 10.1016/ Epub 2017 Aug 18. Review.


TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy.

Ye J, Wang Y, Liu X, Li L, Opejin A, Hsueh EC, Luo H, Wang T, Hawiger D, Peng G.

J Immunol. 2017 Aug 1;199(3):941-954. doi: 10.4049/jimmunol.1601890. Epub 2017 Jun 26.


Peripherally Induced Regulatory T Cells: Recruited Protectors of the Central Nervous System against Autoimmune Neuroinflammation.

Jones A, Hawiger D.

Front Immunol. 2017 May 9;8:532. doi: 10.3389/fimmu.2017.00532. eCollection 2017. Review.


Immunomodulatory Functions of BTLA and HVEM Govern Induction of Extrathymic Regulatory T Cells and Tolerance by Dendritic Cells.

Jones A, Bourque J, Kuehm L, Opejin A, Teague RM, Gross C, Hawiger D.

Immunity. 2016 Nov 15;45(5):1066-1077. doi: 10.1016/j.immuni.2016.10.008. Epub 2016 Oct 25.


Regulation of extrathymic Treg cell conversion by CD5.

Henderson JG, Hawiger D.

Oncotarget. 2015 Sep 29;6(29):26554-5. doi: 10.18632/oncotarget.5809. No abstract available.


Peripherally Induced Tolerance Depends on Peripheral Regulatory T Cells That Require Hopx To Inhibit Intrinsic IL-2 Expression.

Jones A, Opejin A, Henderson JG, Gross C, Jain R, Epstein JA, Flavell RA, Hawiger D.

J Immunol. 2015 Aug 15;195(4):1489-97. doi: 10.4049/jimmunol.1500174. Epub 2015 Jul 13.


CD5 instructs extrathymic regulatory T cell development in response to self and tolerizing antigens.

Henderson JG, Opejin A, Jones A, Gross C, Hawiger D.

Immunity. 2015 Mar 17;42(3):471-83. doi: 10.1016/j.immuni.2015.02.010.


Lack of adiponectin leads to increased lymphocyte activation and increased disease severity in a mouse model of multiple sclerosis.

Piccio L, Cantoni C, Henderson JG, Hawiger D, Ramsbottom M, Mikesell R, Ryu J, Hsieh CS, Cremasco V, Haynes W, Dong LQ, Chan L, Galimberti D, Cross AH.

Eur J Immunol. 2013 Aug;43(8):2089-100. doi: 10.1002/eji.201242836. Epub 2013 Jun 7.


The transcription cofactor Hopx is required for regulatory T cell function in dendritic cell-mediated peripheral T cell unresponsiveness.

Hawiger D, Wan YY, Eynon EE, Flavell RA.

Nat Immunol. 2010 Oct;11(10):962-8. doi: 10.1038/ni.1929. Epub 2010 Aug 29.


Regulatory T cells that become autoaggressive.

Hawiger D, Flavell RA.

Nat Immunol. 2009 Sep;10(9):938-9. doi: 10.1038/ni0909-938.


ICOS mediates the development of insulin-dependent diabetes mellitus in nonobese diabetic mice.

Hawiger D, Tran E, Du W, Booth CJ, Wen L, Dong C, Flavell RA.

J Immunol. 2008 Mar 1;180(5):3140-7.


Inducing and expanding regulatory T cell populations by foreign antigen.

Kretschmer K, Apostolou I, Hawiger D, Khazaie K, Nussenzweig MC, von Boehmer H.

Nat Immunol. 2005 Dec;6(12):1219-27. Epub 2005 Oct 23.


The innate functions of dendritic cells in peripheral lymphoid tissues.

Steinman RM, Bonifaz L, Fujii S, Liu K, Bonnyay D, Yamazaki S, Pack M, Hawiger D, Iyoda T, Inaba K, Nussenzweig MC.

Adv Exp Med Biol. 2005;560:83-97. Review. No abstract available.


Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo.

Hawiger D, Masilamani RF, Bettelli E, Kuchroo VK, Nussenzweig MC.

Immunity. 2004 Jun;20(6):695-705.


Dendritic cell function in vivo during the steady state: a role in peripheral tolerance.

Steinman RM, Hawiger D, Liu K, Bonifaz L, Bonnyay D, Mahnke K, Iyoda T, Ravetch J, Dhodapkar M, Inaba K, Nussenzweig M.

Ann N Y Acad Sci. 2003 Apr;987:15-25. Review.


Tolerogenic dendritic cells.

Steinman RM, Hawiger D, Nussenzweig MC.

Annu Rev Immunol. 2003;21:685-711. Epub 2001 Dec 19. Review.


Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo.

Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, Rivera M, Ravetch JV, Steinman RM, Nussenzweig MC.

J Exp Med. 2001 Sep 17;194(6):769-79.

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