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Items: 1 to 50 of 89

1.

Genome-wide association study reveals novel genetic locus associated with intra-individual variability in response time.

Pinar A, Hawi Z, Cummins T, Johnson B, Pauper M, Tong J, Tiego J, Finlay A, Klein M, Franke B, Fornito A, Bellgrove MA.

Transl Psychiatry. 2018 Oct 4;8(1):207. doi: 10.1038/s41398-018-0262-z.

2.

The role of cadherin genes in five major psychiatric disorders: A literature update.

Hawi Z, Tong J, Dark C, Yates H, Johnson B, Bellgrove MA.

Am J Med Genet B Neuropsychiatr Genet. 2018 Mar;177(2):168-180. doi: 10.1002/ajmg.b.32592. Epub 2017 Sep 18. Review.

PMID:
28921840
3.

Allelic variation in dopamine D2 receptor gene is associated with attentional impulsiveness on the Barratt Impulsiveness Scale (BIS-11).

Taylor JB, Cummins TDR, Fox AM, Johnson BP, Tong JH, Visser TAW, Hawi Z, Bellgrove MA.

World J Biol Psychiatry. 2017 Jan 20:1-9. doi: 10.1080/15622975.2016.1273549. [Epub ahead of print]

PMID:
28000543
4.

Separating the wheat from the chaff: systematic identification of functionally relevant noncoding variants in ADHD.

Tong JH, Hawi Z, Dark C, Cummins TD, Johnson BP, Newman DP, Lau R, Vance A, Heussler HS, Matthews N, Bellgrove MA, Pang KC.

Mol Psychiatry. 2016 Nov;21(11):1589-1598. doi: 10.1038/mp.2016.2. Epub 2016 Apr 26.

PMID:
27113999
5.

Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study.

Hawi Z, Cummins TD, Tong J, Arcos-Burgos M, Zhao Q, Matthews N, Newman DP, Johnson B, Vance A, Heussler HS, Levy F, Easteal S, Wray NR, Kenny E, Morris D, Kent L, Gill M, Bellgrove MA.

Mol Psychiatry. 2017 Apr;22(4):580-584. doi: 10.1038/mp.2016.117. Epub 2016 Jul 26.

PMID:
27457811
6.

Identification and functional characterisation of a novel dopamine beta hydroxylase gene variant associated with attention deficit hyperactivity disorder.

Tong J, McKinley LA, Cummins TD, Johnson B, Matthews N, Vance A, Heussler H, Gill M, Kent L, Bellgrove MA, Hawi Z.

World J Biol Psychiatry. 2015;16(8):610-8. doi: 10.3109/15622975.2015.1036771. Epub 2015 May 15.

PMID:
25975715
7.

An association between a dopamine transporter gene (SLC6A3) haplotype and ADHD symptom measures in nonclinical adults.

Tong JH, Cummins TD, Johnson BP, McKinley LA, Pickering HE, Fanning P, Stefanac NR, Newman DP, Hawi Z, Bellgrove MA.

Am J Med Genet B Neuropsychiatr Genet. 2015 Mar;168B(2):89-96. doi: 10.1002/ajmg.b.32283. Epub 2015 Feb 5.

PMID:
25656223
8.

The molecular genetic architecture of attention deficit hyperactivity disorder.

Hawi Z, Cummins TD, Tong J, Johnson B, Lau R, Samarrai W, Bellgrove MA.

Mol Psychiatry. 2015 Mar;20(3):289-97. doi: 10.1038/mp.2014.183. Epub 2015 Jan 20. Review.

PMID:
25600112
9.

Dopamine transporter genotype is associated with a lateralized resistance to distraction during attention selection.

Newman DP, Cummins TD, Tong JH, Johnson BP, Pickering H, Fanning P, Wagner J, Goodrich JT, Hawi Z, Chambers CD, Bellgrove MA.

J Neurosci. 2014 Nov 19;34(47):15743-50. doi: 10.1523/JNEUROSCI.2327-14.2014.

10.

Methylphenidate side effect profile is influenced by genetic variation in the attention-deficit/hyperactivity disorder-associated CES1 gene.

Johnson KA, Barry E, Lambert D, Fitzgerald M, McNicholas F, Kirley A, Gill M, Bellgrove MA, Hawi Z.

J Child Adolesc Psychopharmacol. 2013 Dec;23(10):655-64. doi: 10.1089/cap.2013.0032.

PMID:
24350812
11.

Alpha-2A adrenergic receptor gene variants are associated with increased intra-individual variability in response time.

Cummins TD, Jacoby O, Hawi Z, Nandam LS, Byrne MA, Kim BN, Wagner J, Chambers CD, Bellgrove MA.

Mol Psychiatry. 2014 Sep;19(9):1031-6. doi: 10.1038/mp.2013.140. Epub 2013 Oct 29.

PMID:
24166412
12.

Human amygdala volume is predicted by common DNA variation in the stathmin and serotonin transporter genes.

Stjepanović D, Lorenzetti V, Yücel M, Hawi Z, Bellgrove MA.

Transl Psychiatry. 2013 Jul 16;3:e283. doi: 10.1038/tp.2013.41.

13.

Norepinephrine genes predict response time variability and methylphenidate-induced changes in neuropsychological function in attention deficit hyperactivity disorder.

Kim BN, Kim JW, Cummins TD, Bellgrove MA, Hawi Z, Hong SB, Yang YH, Kim HJ, Shin MS, Cho SC, Kim JH, Son JW, Shin YM, Chung US, Han DH.

J Clin Psychopharmacol. 2013 Jun;33(3):356-62. doi: 10.1097/JCP.0b013e31828f9fc3.

PMID:
23609393
14.

DNA variation in the SNAP25 gene confers risk to ADHD and is associated with reduced expression in prefrontal cortex.

Hawi Z, Matthews N, Wagner J, Wallace RH, Butler TJ, Vance A, Kent L, Gill M, Bellgrove MA.

PLoS One. 2013 Apr 12;8(4):e60274. doi: 10.1371/journal.pone.0060274. Print 2013.

15.

Neurodevelopmental and neuropsychiatric disorders represent an interconnected molecular system.

Cristino AS, Williams SM, Hawi Z, An JY, Bellgrove MA, Schwartz CE, Costa Lda F, Claudianos C.

Mol Psychiatry. 2014 Mar;19(3):294-301. doi: 10.1038/mp.2013.16. Epub 2013 Feb 26.

PMID:
23439483
16.

A high density linkage disequilibrium mapping in 14 noradrenergic genes: evidence of association between SLC6A2, ADRA1B and ADHD.

Hawi Z, Matthews N, Barry E, Kirley A, Wagner J, Wallace RH, Heussler HS, Vance A, Gill M, Bellgrove MA.

Psychopharmacology (Berl). 2013 Feb;225(4):895-902. doi: 10.1007/s00213-012-2875-x. Epub 2012 Sep 29.

PMID:
23052569
17.

Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3.

Williams NM, Franke B, Mick E, Anney RJ, Freitag CM, Gill M, Thapar A, O'Donovan MC, Owen MJ, Holmans P, Kent L, Middleton F, Zhang-James Y, Liu L, Meyer J, Nguyen TT, Romanos J, Romanos M, Seitz C, Renner TJ, Walitza S, Warnke A, Palmason H, Buitelaar J, Rommelse N, Vasquez AA, Hawi Z, Langley K, Sergeant J, Steinhausen HC, Roeyers H, Biederman J, Zaharieva I, Hakonarson H, Elia J, Lionel AC, Crosbie J, Marshall CR, Schachar R, Scherer SW, Todorov A, Smalley SL, Loo S, Nelson S, Shtir C, Asherson P, Reif A, Lesch KP, Faraone SV.

Am J Psychiatry. 2012 Feb;169(2):195-204.

18.

Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD.

Stergiakouli E, Hamshere M, Holmans P, Langley K, Zaharieva I; deCODE Genetics; Psychiatric GWAS Consortium, Hawi Z, Kent L, Gill M, Williams N, Owen MJ, O'Donovan M, Thapar A.

Am J Psychiatry. 2012 Feb;169(2):186-94.

19.

Dopamine transporter genotype predicts behavioural and neural measures of response inhibition.

Cummins TD, Hawi Z, Hocking J, Strudwick M, Hester R, Garavan H, Wagner J, Chambers CD, Bellgrove MA.

Mol Psychiatry. 2012 Nov;17(11):1086-92. doi: 10.1038/mp.2011.104. Epub 2011 Aug 30.

PMID:
21876545
20.

Allelic expression imbalance of the schizophrenia susceptibility gene CHI3L1: evidence of cis-acting variation and tissue specific regulation.

Hill MJ, Kenny E, Roche S, Morris DW, Corvin A, Hawi Z, Gill M, Anney RJ.

Psychiatr Genet. 2011 Dec;21(6):281-6. doi: 10.1097/YPG.0b013e328348045b.

PMID:
21642896
21.

Epistasis between neurochemical gene polymorphisms and risk for ADHD.

Segurado R, Bellgrove MA, Manconi F, Gill M, Hawi Z.

Eur J Hum Genet. 2011 May;19(5):577-82. doi: 10.1038/ejhg.2010.250. Epub 2011 Feb 2.

22.

fMRI activation during response inhibition and error processing: the role of the DAT1 gene in typically developing adolescents and those diagnosed with ADHD.

Braet W, Johnson KA, Tobin CT, Acheson R, McDonnell C, Hawi Z, Barry E, Mulligan A, Gill M, Bellgrove MA, Robertson IH, Garavan H.

Neuropsychologia. 2011 Jun;49(7):1641-50. doi: 10.1016/j.neuropsychologia.2011.01.001. Epub 2011 Jan 11.

PMID:
21232548
23.

Polymorphisms of the steroid sulfatase (STS) gene are associated with attention deficit hyperactivity disorder and influence brain tissue mRNA expression.

Brookes KJ, Hawi Z, Park J, Scott S, Gill M, Kent L.

Am J Med Genet B Neuropsychiatr Genet. 2010 Dec 5;153B(8):1417-24. doi: 10.1002/ajmg.b.31120. Epub 2010 Sep 22.

24.

Case-control genome-wide association study of attention-deficit/hyperactivity disorder.

Neale BM, Medland S, Ripke S, Anney RJ, Asherson P, Buitelaar J, Franke B, Gill M, Kent L, Holmans P, Middleton F, Thapar A, Lesch KP, Faraone SV, Daly M, Nguyen TT, Schäfer H, Steinhausen HC, Reif A, Renner TJ, Romanos M, Romanos J, Warnke A, Walitza S, Freitag C, Meyer J, Palmason H, Rothenberger A, Hawi Z, Sergeant J, Roeyers H, Mick E, Biederman J; IMAGE II Consortium Group.

J Am Acad Child Adolesc Psychiatry. 2010 Sep;49(9):906-20. doi: 10.1016/j.jaac.2010.06.007. Epub 2010 Aug 5.

25.

Evidence that genetic variation in the oxytocin receptor (OXTR) gene influences social cognition in ADHD.

Park J, Willmott M, Vetuz G, Toye C, Kirley A, Hawi Z, Brookes KJ, Gill M, Kent L.

Prog Neuropsychopharmacol Biol Psychiatry. 2010 May 30;34(4):697-702. doi: 10.1016/j.pnpbp.2010.03.029. Epub 2010 Mar 27.

PMID:
20347913
26.

Haplotype association of calpain 10 gene variants with type 2 diabetes mellitus in an Irish sample.

Alsaraj F, O'Gorman D, McAteer S, McDermott J, Hawi Z, Sreenan S.

Ir J Med Sci. 2010 Jun;179(2):269-72. doi: 10.1007/s11845-010-0462-x. Epub 2010 Feb 2.

PMID:
20119856
27.

Functional analysis of intron 8 and 3' UTR variable number of tandem repeats of SLC6A3: differential activity of intron 8 variants.

Hill M, Anney RJ, Gill M, Hawi Z.

Pharmacogenomics J. 2010 Oct;10(5):442-7. doi: 10.1038/tpj.2009.66. Epub 2009 Dec 22.

PMID:
20029387
28.

Dopaminergic haplotype as a predictor of spatial inattention in children with attention-deficit/hyperactivity disorder.

Bellgrove MA, Johnson KA, Barry E, Mulligan A, Hawi Z, Gill M, Robertson I, Chambers CD.

Arch Gen Psychiatry. 2009 Oct;66(10):1135-42. doi: 10.1001/archgenpsychiatry.2009.120.

PMID:
19805704
29.

Replication of an association of a promoter polymorphism of the dopamine transporter gene and Attention Deficit Hyperactivity Disorder.

Doyle C, Brookes K, Simpson J, Park J, Scott S, Coghill DR, Hawi Z, Kirley A, Gill M, Kent L.

Neurosci Lett. 2009 Sep 22;462(2):179-81. doi: 10.1016/j.neulet.2009.06.084. Epub 2009 Jul 2.

PMID:
19576958
30.

ADHD and DAT1: further evidence of paternal over-transmission of risk alleles and haplotype.

Hawi Z, Kent L, Hill M, Anney RJ, Brookes KJ, Barry E, Franke B, Banaschewski T, Buitelaar J, Ebstein R, Miranda A, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Faraone SV, Asherson P, Gill M.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5;153B(1):97-102. doi: 10.1002/ajmg.b.30960.

PMID:
19388000
31.

Association of the steroid sulfatase (STS) gene with attention deficit hyperactivity disorder.

Brookes KJ, Hawi Z, Kirley A, Barry E, Gill M, Kent L.

Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5;147B(8):1531-5. doi: 10.1002/ajmg.b.30873.

PMID:
18937300
32.

Replication of a rare protective allele in the noradrenaline transporter gene and ADHD.

Xu X, Hawi Z, Brookes KJ, Anney R, Bellgrove M, Franke B, Barry E, Chen W, Kuntsi J, Banaschewski T, Buitelaar J, Ebstein R, Fitzgerald M, Miranda A, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Faraone SV, Gill M, Asherson P.

Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5;147B(8):1564-7. doi: 10.1002/ajmg.b.30872.

33.

Absence of the 7-repeat variant of the DRD4 VNTR is associated with drifting sustained attention in children with ADHD but not in controls.

Johnson KA, Kelly SP, Robertson IH, Barry E, Mulligan A, Daly M, Lambert D, McDonnell C, Connor TJ, Hawi Z, Gill M, Bellgrove MA.

Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5;147B(6):927-37. doi: 10.1002/ajmg.b.30718.

PMID:
18361436
34.

Parent of origin effects in attention/deficit hyperactivity disorder (ADHD): analysis of data from the international multicenter ADHD genetics (IMAGE) program.

Anney RJ, Hawi Z, Sheehan K, Mulligan A, Pinto C, Brookes KJ, Xu X, Zhou K, Franke B, Buitelaar J, Vermeulen SH, Banaschewski T, Sonuga-Barke E, Ebstein R, Manor I, Miranda A, Mulas F, Oades RD, Roeyers H, Rommelse N, Rothenberger A, Sergeant J, Steinhausen HC, Taylor E, Thompson M, Asherson P, Faraone SV, Gill M.

Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5;147B(8):1495-500. doi: 10.1002/ajmg.b.30659.

PMID:
18163388
35.

Apolipoprotein E promoter polymorphisms (-491A/T and -427T/C) and Alzheimer's disease: no evidence of association in the Irish population.

Lynch CA, Brazil J, Cullen B, Coakley D, Gill M, Lawlor BA, Hawi Z.

Ir J Med Sci. 2008 Mar;177(1):29-33. Epub 2007 Dec 5.

PMID:
18057979
36.

Spatial attentional bias as a marker of genetic risk, symptom severity, and stimulant response in ADHD.

Bellgrove MA, Barry E, Johnson KA, Cox M, Dáibhis A, Daly M, Hawi Z, Lambert D, Fitzgerald M, McNicholas F, Robertson IH, Gill M, Kirley A.

Neuropsychopharmacology. 2008 Sep;33(10):2536-45. Epub 2007 Nov 28.

37.

Dopaminergic genotype biases spatial attention in healthy children.

Bellgrove MA, Chambers CD, Johnson KA, Daibhis A, Daly M, Hawi Z, Lambert D, Gill M, Robertson IH.

Mol Psychiatry. 2007 Aug;12(8):786-92. Epub 2007 Jun 5.

PMID:
17549062
38.

Differential dopamine receptor D4 allele association with ADHD dependent of proband season of birth.

Brookes KJ, Neale B, Xu X, Thapar A, Gill M, Langley K, Hawi Z, Mill J, Taylor E, Franke B, Chen W, Ebstein R, Buitelaar J, Banaschewski T, Sonuga-Barke E, Eisenberg J, Manor I, Miranda A, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Faraone SV, Asherson P.

Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 5;147B(1):94-9.

PMID:
17525975
39.

Protein kinase C-beta 1 gene variants are not associated with autism in the Irish population.

Yang MS, Cochrane L, Conroy J, Hawi Z, Fitzgerald M, Gallagher L, Gill M.

Psychiatr Genet. 2007 Feb;17(1):39-41.

PMID:
17167344
40.
41.

No association between TPH2 gene polymorphisms and ADHD in a UK sample.

Sheehan K, Hawi Z, Gill M, Kent L.

Neurosci Lett. 2007 Jan 29;412(2):105-7. Epub 2006 Nov 22.

PMID:
17123708
42.

Impaired temporal resolution of visual attention and dopamine beta hydroxylase genotype in attention-deficit/hyperactivity disorder.

Bellgrove MA, Mattingley JB, Hawi Z, Mullins C, Kirley A, Gill M, Robertson IH.

Biol Psychiatry. 2006 Nov 15;60(10):1039-45. Epub 2006 Jul 28.

PMID:
16876143
43.

Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder.

Hawi Z, Segurado R, Conroy J, Sheehan K, Lowe N, Kirley A, Shields D, Fitzgerald M, Gallagher L, Gill M.

Am J Hum Genet. 2005 Dec;77(6):958-65. Epub 2005 Oct 26.

45.
46.

Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD.

Kent L, Green E, Hawi Z, Kirley A, Dudbridge F, Lowe N, Raybould R, Langley K, Bray N, Fitzgerald M, Owen MJ, O'Donovan MC, Gill M, Thapar A, Craddock N.

Mol Psychiatry. 2005 Oct;10(10):939-43.

PMID:
15940292
47.

Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.

Sheehan K, Lowe N, Kirley A, Mullins C, Fitzgerald M, Gill M, Hawi Z.

Mol Psychiatry. 2005 Oct;10(10):944-9. Erratum in: Mol Psychiatry. 2006 Feb;11(2):221.

PMID:
15940290
48.

DRD4 gene variants and sustained attention in attention deficit hyperactivity disorder (ADHD): effects of associated alleles at the VNTR and -521 SNP.

Bellgrove MA, Hawi Z, Lowe N, Kirley A, Robertson IH, Gill M.

Am J Med Genet B Neuropsychiatr Genet. 2005 Jul 5;136B(1):81-6.

PMID:
15909295
49.

Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: preferential transmission of the MAO-A 941G allele to affected children.

Domschke K, Sheehan K, Lowe N, Kirley A, Mullins C, O'sullivan R, Freitag C, Becker T, Conroy J, Fitzgerald M, Gill M, Hawi Z.

Am J Med Genet B Neuropsychiatr Genet. 2005 Apr 5;134B(1):110-4.

PMID:
15717295
50.

The methionine allele of the COMT polymorphism impairs prefrontal cognition in children and adolescents with ADHD.

Bellgrove MA, Domschke K, Hawi Z, Kirley A, Mullins C, Robertson IH, Gill M.

Exp Brain Res. 2005 Jun;163(3):352-60. Epub 2005 Jan 15.

PMID:
15654584

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