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Items: 1 to 50 of 62

1.

A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies.

Skokos D, Waite JC, Haber L, Crawford A, Hermann A, Ullman E, Slim R, Godin S, Ajithdoss D, Ye X, Wang B, Wu Q, Ramos I, Pawashe A, Canova L, Vazzana K, Ram P, Herlihy E, Ahmed H, Oswald E, Golubov J, Poon P, Havel L, Chiu D, Lazo M, Provoncha K, Yu K, Kim J, Warsaw JJ, Stokes Oristian N, Siao CJ, Dudgeon D, Huang T, Potocky T, Martin J, MacDonald D, Oyejide A, Rafique A, Poueymirou W, Kirshner JR, Smith E, Olson W, Lin J, Thurston G, Sleeman MA, Murphy AJ, Yancopoulos GD.

Sci Transl Med. 2020 Jan 8;12(525). pii: eaaw7888. doi: 10.1126/scitranslmed.aaw7888.

PMID:
31915305
2.

Non-small Cell Lung Cancer as a Chronic Disease - A Prospective Study from the Czech TULUNG Registry.

Bratova M, Karlinova B, Skrickova J, Pesek M, Kolek V, Koubkova L, Hrnciarik M, Krejci J, Barinova M, Havel L, Grygarkova I, Brat K.

In Vivo. 2020 Jan-Feb;34(1):369-379. doi: 10.21873/invivo.11783.

PMID:
31882501
3.

Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial.

Paz-Ares L, Dvorkin M, Chen Y, Reinmuth N, Hotta K, Trukhin D, Statsenko G, Hochmair MJ, Özgüroğlu M, Ji JH, Voitko O, Poltoratskiy A, Ponce S, Verderame F, Havel L, Bondarenko I, Kazarnowicz A, Losonczy G, Conev NV, Armstrong J, Byrne N, Shire N, Jiang H, Goldman JW; CASPIAN investigators.

Lancet. 2019 Nov 23;394(10212):1929-1939. doi: 10.1016/S0140-6736(19)32222-6. Epub 2019 Oct 4.

PMID:
31590988
4.

ASO Author Reflections: Rapid Uptake of the SSO ASTRO Margin Guideline and Decreased Reoperations After Lumpectomy: A Success Story.

Havel L, Landercasper J.

Ann Surg Oncol. 2019 May;26(5):1245-1246. doi: 10.1245/s10434-019-07289-9. Epub 2019 Mar 8. No abstract available.

PMID:
30850902
5.

Impact of the SSO-ASTRO Margin Guideline on Rates of Re-excision After Lumpectomy for Breast Cancer: A Meta-analysis.

Havel L, Naik H, Ramirez L, Morrow M, Landercasper J.

Ann Surg Oncol. 2019 May;26(5):1238-1244. doi: 10.1245/s10434-019-07247-5. Epub 2019 Feb 21.

PMID:
30790112
6.

First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer.

Horn L, Mansfield AS, Szczęsna A, Havel L, Krzakowski M, Hochmair MJ, Huemer F, Losonczy G, Johnson ML, Nishio M, Reck M, Mok T, Lam S, Shames DS, Liu J, Ding B, Lopez-Chavez A, Kabbinavar F, Lin W, Sandler A, Liu SV; IMpower133 Study Group.

N Engl J Med. 2018 Dec 6;379(23):2220-2229. doi: 10.1056/NEJMoa1809064. Epub 2018 Sep 25.

PMID:
30280641
7.

Beyond Informed Consent: Talking to Patients About Therapeutic Action.

Lenet AE, Holoshitz Y, Havel LK, Cabaniss DL.

Am J Psychother. 2018 Oct 1;71(2):51-54. doi: 10.1176/appi.psychotherapy.20180010. Epub 2018 Jul 17.

PMID:
30016128
8.

Immune reprogramming via PD-1 inhibition enhances early-stage lung cancer survival.

Markowitz GJ, Havel LS, Crowley MJ, Ban Y, Lee SB, Thalappillil JS, Narula N, Bhinder B, Elemento O, Wong ST, Gao D, Altorki NK, Mittal V.

JCI Insight. 2018 Jul 12;3(13). pii: 96836. doi: 10.1172/jci.insight.96836.

9.

Effects of copper and arsenic stress on the development of Norway spruce somatic embryos and their visualization with the environmental scanning electron microscope.

Đorđević B, Neděla V, Tihlaříková E, Trojan V, Havel L.

N Biotechnol. 2019 Jan 25;48:35-43. doi: 10.1016/j.nbt.2018.05.005. Epub 2018 May 18.

PMID:
29782934
10.

Vimentin Is Required for Lung Adenocarcinoma Metastasis via Heterotypic Tumor Cell-Cancer-Associated Fibroblast Interactions during Collective Invasion.

Richardson AM, Havel LS, Koyen AE, Konen JM, Shupe J, Wiles WG 4th, Martin WD, Grossniklaus HE, Sica G, Gilbert-Ross M, Marcus AI.

Clin Cancer Res. 2018 Jan 15;24(2):420-432. doi: 10.1158/1078-0432.CCR-17-1776. Epub 2017 Dec 5.

11.

First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer.

Carbone DP, Reck M, Paz-Ares L, Creelan B, Horn L, Steins M, Felip E, van den Heuvel MM, Ciuleanu TE, Badin F, Ready N, Hiltermann TJN, Nair S, Juergens R, Peters S, Minenza E, Wrangle JM, Rodriguez-Abreu D, Borghaei H, Blumenschein GR Jr, Villaruz LC, Havel L, Krejci J, Corral Jaime J, Chang H, Geese WJ, Bhagavatheeswaran P, Chen AC, Socinski MA; CheckMate 026 Investigators.

N Engl J Med. 2017 Jun 22;376(25):2415-2426. doi: 10.1056/NEJMoa1613493.

12.

Identification of Alleles of Puroindoline Genes and Their Effect on Wheat (Triticum aestivum L.) Grain Texture.

Presinszká M, Štiasna K, Vyhnánek T, Trojan V, Mrkvicová E, Hřivna L, Havel L.

Food Technol Biotechnol. 2016 Mar;54(1):103-107.

13.

Bottlenecks in bog pine multiplication by somatic embryogenesis and their visualization with the environmental scanning electron microscope.

Vlašínová H, Neděla V, Đorđević B, Havel L.

Protoplasma. 2017 Jul;254(4):1487-1497. doi: 10.1007/s00709-016-1036-1. Epub 2016 Oct 25.

PMID:
27783182
14.

Phase III Randomized Trial of Ipilimumab Plus Etoposide and Platinum Versus Placebo Plus Etoposide and Platinum in Extensive-Stage Small-Cell Lung Cancer.

Reck M, Luft A, Szczesna A, Havel L, Kim SW, Akerley W, Pietanza MC, Wu YL, Zielinski C, Thomas M, Felip E, Gold K, Horn L, Aerts J, Nakagawa K, Lorigan P, Pieters A, Kong Sanchez T, Fairchild J, Spigel D.

J Clin Oncol. 2016 Nov 1;34(31):3740-3748. doi: 10.1200/JCO.2016.67.6601. Erratum in: J Clin Oncol. 2019 Dec 1;37(34):3327.

PMID:
27458307
15.

Thinking Outside of Outpatient: Underutilized Settings for Psychotherapy Education.

Blumenshine P, Lenet AE, Havel LK, Arbuckle MR, Cabaniss DL.

Acad Psychiatry. 2017 Feb;41(1):16-19. doi: 10.1007/s40596-016-0554-7. Epub 2016 Jun 9.

PMID:
27283018
16.

Oral vinorelbine plus cisplatin versus pemetrexed plus cisplatin as first-line treatment of advanced non-squamous non-small-cell lung cancer: cost minimization analysis in 12 European countries.

Grossi F, Bennouna J, Havel L, Hochmair M, Almodovar T.

Curr Med Res Opin. 2016 Sep;32(9):1577-84. doi: 10.1080/03007995.2016.1190700. Epub 2016 Jul 7.

PMID:
27223813
17.

Smartphones, Smart Feedback: Using Mobile Devices to Collect In-the-Moment Feedback.

Havel LK, Powell SD, Cabaniss DL, Arbuckle MR.

Acad Psychiatry. 2017 Feb;41(1):76-80. doi: 10.1007/s40596-016-0564-5. Epub 2016 May 9.

PMID:
27160895
18.

Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled, phase 3 trial.

Vansteenkiste JF, Cho BC, Vanakesa T, De Pas T, Zielinski M, Kim MS, Jassem J, Yoshimura M, Dahabreh J, Nakayama H, Havel L, Kondo H, Mitsudomi T, Zarogoulidis K, Gladkov OA, Udud K, Tada H, Hoffman H, Bugge A, Taylor P, Gonzalez EE, Liao ML, He J, Pujol JL, Louahed J, Debois M, Brichard V, Debruyne C, Therasse P, Altorki N.

Lancet Oncol. 2016 Jun;17(6):822-835. doi: 10.1016/S1470-2045(16)00099-1. Epub 2016 Apr 27.

PMID:
27132212
19.

Imaging of Norway spruce early somatic embryos with the ESEM, Cryo-SEM and laser scanning microscope.

Neděla V, Hřib J, Havel L, Hudec J, Runštuk J.

Micron. 2016 May;84:67-71. doi: 10.1016/j.micron.2016.02.011. Epub 2016 Mar 2.

PMID:
26954464
20.

[Present Experience and Perspectives of Immunotherapy of Lung Cancer].

Havel L.

Klin Onkol. 2015;28 Suppl 4:4S73-6. Review. Czech.

PMID:
26647893
21.

The Microprocess Moment: A Tool for Evaluating Skills in Psychodynamic Psychotherapy.

Cabaniss DL, Havel LK, Berger S, Deo A, Arbuckle MR.

Acad Psychiatry. 2017 Feb;41(1):51-54. doi: 10.1007/s40596-015-0450-6. Epub 2015 Dec 8. No abstract available.

PMID:
26646408
22.

Are Early Somatic Embryos of the Norway Spruce (Picea abies (L.) Karst.) Organised?

Petrek J, Zitka O, Adam V, Bartusek K, Anjum NA, Pereira E, Havel L, Kizek R.

PLoS One. 2015 Dec 1;10(12):e0144093. doi: 10.1371/journal.pone.0144093. eCollection 2015.

23.

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer.

Brahmer J, Reckamp KL, Baas P, Crinò L, Eberhardt WE, Poddubskaya E, Antonia S, Pluzanski A, Vokes EE, Holgado E, Waterhouse D, Ready N, Gainor J, Arén Frontera O, Havel L, Steins M, Garassino MC, Aerts JG, Domine M, Paz-Ares L, Reck M, Baudelet C, Harbison CT, Lestini B, Spigel DR.

N Engl J Med. 2015 Jul 9;373(2):123-35. doi: 10.1056/NEJMoa1504627. Epub 2015 May 31.

24.

FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells.

Taliaferro-Smith L, Oberlick E, Liu T, McGlothen T, Alcaide T, Tobin R, Donnelly S, Commander R, Kline E, Nagaraju GP, Havel L, Marcus A, Nahta R, O'Regan R.

Oncotarget. 2015 Mar 10;6(7):4757-72.

25.

Oral vinorelbine plus cisplatin as first-line chemotherapy in nonsquamous non-small-cell lung cancer: final results of an International randomized phase II study (NAVotrial 01).

Bennouna J, Havel L, Krzakowski M, Kollmeier J, Gervais R, Dansin E, Serke M, Favaretto A, Szczesna A, Cobo M, Ciuffreda L, Jassem J, Nicolini M, Ramlau R, Amoroso D, Melotti B, Almodovar T, Riggi M, Caux NR, Vaissière N, Tan EH.

Clin Lung Cancer. 2014 Jul;15(4):258-65. doi: 10.1016/j.cllc.2014.04.007. Epub 2014 May 15.

PMID:
24954228
26.

Vimentin regulates lung cancer cell adhesion through a VAV2-Rac1 pathway to control focal adhesion kinase activity.

Havel LS, Kline ER, Salgueiro AM, Marcus AI.

Oncogene. 2015 Apr 9;34(15):1979-90. doi: 10.1038/onc.2014.123. Epub 2014 May 26.

27.

Randomised phase II study of axitinib or bevacizumab combined with paclitaxel/carboplatin as first-line therapy for patients with advanced non-small-cell lung cancer.

Twelves C, Chmielowska E, Havel L, Popat S, Swieboda-Sadlej A, Sawrycki P, Bycott P, Ingrosso A, Kim S, Williams JA, Chen C, Olszanski AJ, de Besi P, Schiller JH.

Ann Oncol. 2014 Jan;25(1):132-8. doi: 10.1093/annonc/mdt489.

28.

Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind, phase 3 trial.

Butts C, Socinski MA, Mitchell PL, Thatcher N, Havel L, Krzakowski M, Nawrocki S, Ciuleanu TE, Bosquée L, Trigo JM, Spira A, Tremblay L, Nyman J, Ramlau R, Wickart-Johansson G, Ellis P, Gladkov O, Pereira JR, Eberhardt WE, Helwig C, Schröder A, Shepherd FA; START trial team.

Lancet Oncol. 2014 Jan;15(1):59-68. doi: 10.1016/S1470-2045(13)70510-2. Epub 2013 Dec 9.

29.

Erlotinib in the treatment of advanced squamous cell NSCLC.

Fiala O, Pesek M, Finek J, Krejci J, Havel L, Hrnciarik M, Salajka F, Bortlicek Z, Benesova L, Minarik M.

Neoplasma. 2013;60(6):676-82. doi: 10.4149/neo_2013_086.

PMID:
23906302
30.

[The TULUNG clinical registry].

Spelda S, Skřičková J, Bortlíček Z, Hejduk K, Pešek M, Zatloukal P, Kolek V, Salajka F, Koubková L, Tomíšková M, Grygárková Y, Havel L, Hrnčiarik M, Zemanová M, Sixtová D, Roubec J, Coupková H, Košatová K.

Klin Onkol. 2012;25(5):383-4. Czech. No abstract available.

PMID:
23102201
31.

Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation.

Havel LS, Wang CE, Wade B, Huang B, Li S, Li XJ.

Hum Mol Genet. 2011 Apr 1;20(7):1424-37. doi: 10.1093/hmg/ddr023. Epub 2011 Jan 18.

32.

Effects of various doses of selenite on stinging nettle (Urtica dioica L.).

Krystofova O, Adam V, Babula P, Zehnalek J, Beklova M, Havel L, Kizek R.

Int J Environ Res Public Health. 2010 Oct;7(10):3804-15. doi: 10.3390/ijerph7103804. Epub 2010 Oct 22.

33.

Fully automated spectrometric protocols for determination of antioxidant activity: advantages and disadvantages.

Sochor J, Ryvolova M, Krystofova O, Salas P, Hubalek J, Adam V, Trnkova L, Havel L, Beklova M, Zehnalek J, Provaznik I, Kizek R.

Molecules. 2010 Nov 29;15(12):8618-40. doi: 10.3390/molecules15128618.

34.

[TARCEVA Clinical Registry].

Skricková J, Pesek M, Zatloukal P, Kolek V, Salajka F, Koubková L, Krejcí J, Tomísková M, Grygárková Y, Havel L, Hrnciarik M, Skalová B, Stícha M.

Klin Onkol. 2010;23(5):361-3. Czech. No abstract available.

PMID:
21061685
35.

A long-term survey of heavy metals and specific organic compounds in biofilms, sediments, and surface water in a heavily affected river in the Czech Republic.

Kohušová K, Havel L, Vlasák P, Tonika J.

Environ Monit Assess. 2011 Mar;174(1-4):555-72. doi: 10.1007/s10661-010-1478-4. Epub 2010 May 13.

PMID:
20461551
36.

Validated method for bioactive lignans in Schisandra chinensis in vitro cultures using a solid phase extraction and a monolithic column application.

Brezinová L, Vlasínová H, Havel L, Humpa O, Slanina J.

Biomed Chromatogr. 2010 Sep;24(9):954-60. doi: 10.1002/bmc.1391.

PMID:
20082284
37.

Nuclear accumulation of polyglutamine disease proteins and neuropathology.

Havel LS, Li S, Li XJ.

Mol Brain. 2009 Jul 3;2:21. doi: 10.1186/1756-6606-2-21. Review.

38.

Automated nucleic acids isolation using paramagnetic microparticles coupled with electrochemical detection.

Huska D, Hubalek J, Adam V, Vajtr D, Horna A, Trnkova L, Havel L, Kizek R.

Talanta. 2009 Jul 15;79(2):402-11. doi: 10.1016/j.talanta.2009.04.007. Epub 2009 Apr 10.

PMID:
19559897
39.

Phytohormones as important biologically active molecules--their simple simultaneous detection.

Diopan V, Adam V, Havel L, Kizek R.

Molecules. 2009 May 15;14(5):1825-39. doi: 10.3390/molecules14051825.

40.

Silver(I) ions ultrasensitive detection at carbon electrodes-analysis of waters, tobacco cells and fish tissues.

Krizkova S, Krystofova O, Trnkova L, Hubalek J, Adam V, Beklova M, Horna A, Havel L, Kizek R.

Sensors (Basel). 2009;9(9):6934-50. doi: 10.3390/s90906934. Epub 2009 Sep 1.

41.

Electrochemical and spectrometric study of antioxidant activity of pomiferin, isopomiferin, osajin and catalposide.

Diopan V, Babula P, Shestivska V, Adam V, Zemlicka M, Dvorska M, Hubalek J, Trnkova L, Havel L, Kizek R.

J Pharm Biomed Anal. 2008 Sep 10;48(1):127-33. doi: 10.1016/j.jpba.2008.05.025. Epub 2008 May 28.

PMID:
18597965
42.

Influence of Cadmium(II) Ions and Brewery Sludge on Metallothionein Level in Earthworms (Eisenia fetida) - Bio- transforming of Toxic Wastes.

Huska D, Krizkova S, Beklova M, Havel L, Zehnalek J, Diopan V, Adam V, Zeman L, Babula P, Kizek R.

Sensors (Basel). 2008 Feb 19;8(2):1039-1047.

43.

Multi-instrumental Analysis of Tissues of Sunflower Plants Treated with Silver(I) Ions - Plants as Bioindicators of Environmental Pollution.

Krizkova S, Ryant P, Krystofova O, Adam V, Galiova M, Beklova M, Babula P, Kaiser J, Novotny K, Novotny J, Liska M, Malina R, Zehnalek J, Hubalek J, Havel L, Kizek R.

Sensors (Basel). 2008 Jan 24;8(1):445-463.

44.

Affecting of aquatic vascular plant Lemna minor by cisplatin revealed by voltammetry.

Supalkova V, Beklova M, Baloun J, Singer C, Sures B, Adam V, Huska D, Pikula J, Rauscherova L, Havel L, Zehnalek J, Kizek R.

Bioelectrochemistry. 2008 Feb;72(1):59-65. doi: 10.1016/j.bioelechem.2007.11.012. Epub 2007 Dec 4.

PMID:
18201947
45.

[Naphthoquinones and their pharmacological properties].

Babula P, Adam V, Havel L, Kizek R.

Ceska Slov Farm. 2007 Jun;56(3):114-20. Review. Czech.

PMID:
17867522
46.

Electrochemical determination of Ag-ions in environment waters and their action on plant embryos.

Mikelova R, Baloun J, Petrlova J, Adam V, Havel L, Petrek J, Horna A, Kizek R.

Bioelectrochemistry. 2007 May;70(2):508-18. Epub 2006 Dec 16.

PMID:
17251068
47.

Interactions between smoking and other exposures associated with lung cancer risk in women: diet and physical activity.

Kubík A, Zatloukal P, Tomásek L, Pauk N, Havel L, Dolezal J, Plesko I.

Neoplasma. 2007;54(1):83-8.

PMID:
17203897
48.

Paenibacillus sepulcri sp. nov., isolated from biodeteriorated mural paintings in the Servilia tomb.

Smerda J, Sedlácek I, Pácová Z, Krejcí E, Havel L.

Int J Syst Evol Microbiol. 2006 Oct;56(Pt 10):2341-4.

PMID:
17012558
49.

[Naphthoquinones--biosynthesis, occurrence and metabolism in plants].

Babula P, Mikelová R, Adam V, Kizek R, Havel L, Sladký Z.

Ceska Slov Farm. 2006 Jul;55(4):151-9. Review. Czech.

PMID:
16921733
50.

Simultaneous determination of eight biologically active thiol compounds using gradient elution-liquid chromatography with Coul-Array detection.

Petrlova J, Mikelova R, Stejskal K, Kleckerova A, Zitka O, Petrek J, Havel L, Zehnalek J, Vojtech A, Trnkova L, Kizek R.

J Sep Sci. 2006 May;29(8):1166-73.

PMID:
16830732

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