Sort by
Items per page

Send to

Choose Destination

Search results

Items: 20


A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics.

Hava DL, Tan L, Johnson P, Curran AK, Perry J, Kramer S, Kane K, Bedwell P, Layton G, Swann C, Henderson D, Khan N, Connor L, McKenzie L, Singh D, Roach J.

Br J Clin Pharmacol. 2019 Nov 6. doi: 10.1111/bcp.14166. [Epub ahead of print]


Pulmonary and Regional Deposition of Nebulized and Dry Powder Aerosols in Ferrets.

Kuehl PJ, Chand R, McDonald JD, Hava DL, DeHaan WH.

AAPS PharmSciTech. 2019 Jul 1;20(6):242. doi: 10.1208/s12249-019-1382-3.


Particle size and gastrointestinal absorption influence tiotropium pharmacokinetics: a pilot bioequivalence study of PUR0200 and Spiriva HandiHaler.

Perry J, Trautman B, Takher-Smith J, Kramer S, Kane K, Silverman M, Tan L, Haughie S, Richter W, Kirkov V, Arsova S, Ward J, Hava DL.

Br J Clin Pharmacol. 2019 Mar;85(3):580-589. doi: 10.1111/bcp.13831. Epub 2019 Jan 15.


Inhaled calcium salts inhibit tobacco smoke-induced inflammation by modulating expression of chemokines and cytokines.

Andreotta PW, Arold S, Kenyon J, Spicer D, Woodman P, Berry E, Brogan T, Kong S, Okerholm P, Russell V, Clarke RW, Hava DL.

Pulm Pharmacol Ther. 2018 Dec;53:86-99. doi: 10.1016/j.pupt.2018.10.004. Epub 2018 Oct 22.


The pharmacokinetics, pharmacodynamics and tolerability of PUR0200, a novel tiotropium formulation, in chronic obstructive pulmonary disease.

Singh D, Ravi A, Kane K, Schmalbach T, Hava DL.

Br J Clin Pharmacol. 2018 Sep;84(9):2097-2105. doi: 10.1111/bcp.13645. Epub 2018 Jul 10.


Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model--a clinical trial.

Holz O, Biller H, Mueller M, Kane K, Rosano M, Hanrahan J, Hava DL, Hohlfeld JM.

BMC Pharmacol Toxicol. 2015 Aug 12;16:21. doi: 10.1186/s40360-015-0021-1.


Calcium restores the macrophage response to nontypeable haemophilus influenzae in chronic obstructive pulmonary disease.

Provost KA, Smith M, Arold SP, Hava DL, Sethi S.

Am J Respir Cell Mol Biol. 2015 Jun;52(6):728-37. doi: 10.1165/rcmb.2014-0172OC.


Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b.

Garg S, Sharma M, Ung C, Tuli A, Barral DC, Hava DL, Veerapen N, Besra GS, Hacohen N, Brenner MB.

Immunity. 2011 Aug 26;35(2):182-93. doi: 10.1016/j.immuni.2011.06.009. Epub 2011 Jul 28.


Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation.

Hava DL, van der Wel N, Cohen N, Dascher CC, Houben D, León L, Agarwal S, Sugita M, van Zon M, Kent SC, Shams H, Peters PJ, Brenner MB.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11281-6. doi: 10.1073/pnas.0804681105. Epub 2008 Aug 6.


Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules.

Kaser A, Hava DL, Dougan SK, Chen Z, Zeissig S, Brenner MB, Blumberg RS.

Eur J Immunol. 2008 Aug;38(8):2351-9. doi: 10.1002/eji.200738102.


Serum lipids regulate dendritic cell CD1 expression and function.

Leslie DS, Dascher CC, Cembrola K, Townes MA, Hava DL, Hugendubler LC, Mueller E, Fox L, Roura-Mir C, Moody DB, Vincent MS, Gumperz JE, Illarionov PA, Besra GS, Reynolds CG, Brenner MB.

Immunology. 2008 Nov;125(3):289-301. doi: 10.1111/j.1365-2567.2008.02842.x. Epub 2008 Apr 28.


CD1 assembly and the formation of CD1-antigen complexes.

Hava DL, Brigl M, van den Elzen P, Zajonc DM, Wilson IA, Brenner MB.

Curr Opin Immunol. 2005 Feb;17(1):88-94. Review.


From nose to lung: the regulation behind Streptococcus pneumoniae virulence factors.

Hava DL, LeMieux J, Camilli A.

Mol Microbiol. 2003 Nov;50(4):1103-10. Review.


Transcriptional regulation in the Streptococcus pneumoniae rlrA pathogenicity islet by RlrA.

Hava DL, Hemsley CJ, Camilli A.

J Bacteriol. 2003 Jan;185(2):413-21.


Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae.

Merrell DS, Hava DL, Camilli A.

Mol Microbiol. 2002 Mar;43(6):1471-91.


Regulation and temporal expression patterns of Vibrio cholerae virulence genes during infection.

Lee SH, Hava DL, Waldor MK, Camilli A.

Cell. 1999 Dec 10;99(6):625-34.

Supplemental Content

Support Center