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Items: 1 to 50 of 124

1.

Ceramide Accumulation Is Associated with Declining Verbal Memory in Coronary Artery Disease Patients: An Observational Study.

Chan P, Saleem M, Herrmann N, Mielke MM, Haughey NJ, Oh PI, Kiss A, Lanctôt KL.

J Alzheimers Dis. 2018 Jun 28. doi: 10.3233/JAD-180030. [Epub ahead of print]

PMID:
30010121
2.

TNFα and IL-1β modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons.

Chaudhuri AD, Dastgheyb RM, Yoo SW, Trout A, Talbot CC Jr, Hao H, Witwer KW, Haughey NJ.

Cell Death Dis. 2018 Mar 5;9(3):363. doi: 10.1038/s41419-018-0369-4.

3.

Pharmacokinetics of Intranasal versus Subcutaneous Insulin in the Mouse.

Nedelcovych MT, Gadiano AJ, Wu Y, Manning AA, Thomas AG, Khuder SS, Yoo SW, Xu J, McArthur JC, Haughey NJ, Volsky DJ, Rais R, Slusher BS.

ACS Chem Neurosci. 2018 Apr 18;9(4):809-816. doi: 10.1021/acschemneuro.7b00434. Epub 2018 Jan 4.

4.

Plasma sphingolipids and depressive symptoms in coronary artery disease.

Dinoff A, Saleem M, Herrmann N, Mielke MM, Oh PI, Venkata SLV, Haughey NJ, Lanctôt KL.

Brain Behav. 2017 Sep 26;7(11):e00836. doi: 10.1002/brb3.836. eCollection 2017 Nov.

5.

Proceedings of the 2017 ISEV symposium on "HIV, NeuroHIV, drug abuse, & EVs".

Hu G, Yelamanchili S, Kashanchi F, Haughey N, Bond VC, Witwer KW, Pulliam L, Buch S.

J Neurovirol. 2017 Dec;23(6):935-940. doi: 10.1007/s13365-017-0599-8. Epub 2017 Nov 16.

PMID:
29147885
6.

Short communication: Circulating fatty acylcarnitines are elevated in overweight periparturient dairy cows in association with sphingolipid biomarkers of insulin resistance.

Rico JE, Zang Y, Haughey NJ, Rius AG, McFadden JW.

J Dairy Sci. 2018 Jan;101(1):812-819. doi: 10.3168/jds.2017-13171. Epub 2017 Nov 2.

PMID:
29103713
7.

Paroxetine and fluconazole therapy for HIV-associated neurocognitive impairment: results from a double-blind, placebo-controlled trial.

Sacktor N, Skolasky RL, Moxley R, Wang S, Mielke MM, Munro C, Steiner J, Nath A, Haughey N, McArthur J.

J Neurovirol. 2018 Feb;24(1):16-27. doi: 10.1007/s13365-017-0587-z. Epub 2017 Oct 23.

PMID:
29063516
8.

Sphingolipids and microRNA Changes in Blood following Blast Traumatic Brain Injury: An Exploratory Study.

Sajja VSSS, Jablonska A, Haughey N, Bulte JWM, Stevens RD, Long JB, Walczak P, Janowski M.

J Neurotrauma. 2018 Jan 15;35(2):353-361. doi: 10.1089/neu.2017.5009. Epub 2017 Nov 17.

PMID:
29020847
9.

Internal grant review to increase grant funding for junior investigators.

Thomas HS, Brodsky MB, Ewen JB, Bergey GK, Lloyd TE, Haughey NJ, Marvel CL.

Ann Neurol. 2017 Oct;82(4):497-502. doi: 10.1002/ana.25040. Epub 2017 Oct 4. No abstract available.

PMID:
28869672
10.

Circulating endothelial cell-derived extracellular vesicles mediate the acute phase response and sickness behaviour associated with CNS inflammation.

Couch Y, Akbar N, Roodselaar J, Evans MC, Gardiner C, Sargent I, Romero IA, Bristow A, Buchan AM, Haughey N, Anthony DC.

Sci Rep. 2017 Aug 29;7(1):9574. doi: 10.1038/s41598-017-09710-3.

11.

Proceedings of the ISEV symposium on "HIV, NeuroAIDS, drug abuse & EVs".

Hu G, Witwer KW, Bond VC, Haughey N, Kashanchi F, Pulliam L, Buch S.

J Extracell Vesicles. 2017 Mar 10;6(1):1294360. doi: 10.1080/20013078.2017.1294360. eCollection 2017.

12.

Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging.

Dickens AM, Yoo SW, Chin AC, Xu J, Johnson TP, Trout AL, Hauser KF, Haughey NJ.

Sci Rep. 2017 Aug 10;7(1):7748. doi: 10.1038/s41598-017-07570-5.

13.

Efficacy of nutritional interventions to lower circulating ceramides in young adults: FRUVEDomic pilot study.

Mathews AT, Famodu OA, Olfert MD, Murray PJ, Cuff CF, Downes MT, Haughey NJ, Colby SE, Chantler PD, Olfert IM, McFadden JW.

Physiol Rep. 2017 Jul;5(13). pii: e13329. doi: 10.14814/phy2.13329.

14.

A Lipidomics Approach to Assess the Association Between Plasma Sphingolipids and Verbal Memory Performance in Coronary Artery Disease Patients Undertaking Cardiac Rehabilitation: A C18:0 Signature for Cognitive Response to Exercise.

Saleem M, Herrmann N, Dinoff A, Mielke MM, Oh PI, Shammi P, Cao X, Venkata SLV, Haughey NJ, Lanctôt KL.

J Alzheimers Dis. 2017;60(3):829-841. doi: 10.3233/JAD-161292.

15.

Modifications in acute phase and complement systems predict shifts in cognitive status of HIV-infected patients.

Ubaida-Mohien C, Lamberty B, Dickens AM, Mielke MM, Marcotte T, Sacktor N, Grant I, Letendre S, Franklin D, Cibrowski P, Tharakan R, McArthur JC, Fox H, Haughey NJ.

AIDS. 2017 Jun 19;31(10):1365-1378. doi: 10.1097/QAD.0000000000001503.

16.

The Psychiatric Impact of HIV.

Nedelcovych MT, Manning AA, Semenova S, Gamaldo C, Haughey NJ, Slusher BS.

ACS Chem Neurosci. 2017 Jul 19;8(7):1432-1434. doi: 10.1021/acschemneuro.7b00169. Epub 2017 May 24.

17.

Temporal changes in sphingolipids and systemic insulin sensitivity during the transition from gestation to lactation.

Rico JE, Saed Samii S, Mathews AT, Lovett J, Haughey NJ, McFadden JW.

PLoS One. 2017 May 9;12(5):e0176787. doi: 10.1371/journal.pone.0176787. eCollection 2017.

18.

Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.

Dickens AM, Tovar-Y-Romo LB, Yoo SW, Trout AL, Bae M, Kanmogne M, Megra B, Williams DW, Witwer KW, Gacias M, Tabatadze N, Cole RN, Casaccia P, Berman JW, Anthony DC, Haughey NJ.

Sci Signal. 2017 Apr 4;10(473). pii: eaai7696. doi: 10.1126/scisignal.aai7696.

19.

HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity.

Hategan A, Bianchet MA, Steiner J, Karnaukhova E, Masliah E, Fields A, Lee MH, Dickens AM, Haughey N, Dimitriadis EK, Nath A.

Nat Struct Mol Biol. 2017 Apr;24(4):379-386. doi: 10.1038/nsmb.3379. Epub 2017 Feb 20.

20.

Hippocampal encoding of interoceptive context during fear conditioning.

Yoo SW, Bae M, Tovar-Y-Romo LB, Haughey NJ.

Transl Psychiatry. 2017 Jan 3;7(1):e991. doi: 10.1038/tp.2016.254.

21.

The Association Between Plasma Ceramides and Sphingomyelins and Risk of Alzheimer's Disease Differs by Sex and APOE in the Baltimore Longitudinal Study of Aging.

Mielke MM, Haughey NJ, Han D, An Y, Bandaru VVR, Lyketsos CG, Ferrucci L, Resnick SM.

J Alzheimers Dis. 2017;60(3):819-828. doi: 10.3233/JAD-160925.

22.

HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.

Gannon PJ, Akay-Espinoza C, Yee AC, Briand LA, Erickson MA, Gelman BB, Gao Y, Haughey NJ, Zink MC, Clements JE, Kim NS, Van De Walle G, Jensen BK, Vassar R, Pierce RC, Gill AJ, Kolson DL, Diehl JA, Mankowski JL, Jordan-Sciutto KL.

Am J Pathol. 2017 Jan;187(1):91-109. doi: 10.1016/j.ajpath.2016.09.006.

23.

Palmitic acid feeding increases ceramide supply in association with increased milk yield, circulating nonesterified fatty acids, and adipose tissue responsiveness to a glucose challenge.

Rico JE, Mathews AT, Lovett J, Haughey NJ, McFadden JW.

J Dairy Sci. 2016 Nov;99(11):8817-8830. doi: 10.3168/jds.2016-11296. Epub 2016 Sep 13.

PMID:
27638262
24.

Humoral Dysregulation Associated with Increased Systemic Inflammation among Injection Heroin Users.

Piepenbrink MS, Samuel M, Zheng B, Carter B, Fucile C, Bunce C, Kiebala M, Khan AA, Thakar J, Maggirwar SB, Morse D, Rosenberg AF, Haughey NJ, Valenti W, Keefer MC, Kobie JJ.

PLoS One. 2016 Jul 5;11(7):e0158641. doi: 10.1371/journal.pone.0158641. eCollection 2016.

25.

Post-cardiotomy open chest management. A single-unit experience.

Haughey N, Booth K, Parissis H.

Asian Cardiovasc Thorac Ann. 2016 Jul;24(6):530-4. doi: 10.1177/0218492316655033. Epub 2016 Jun 7.

PMID:
27273233
26.

Peripheral sphingolipids are associated with variation in white matter microstructure in older adults.

Gonzalez CE, Venkatraman VK, An Y, Landman BA, Davatzikos C, Ratnam Bandaru VV, Haughey NJ, Ferrucci L, Mielke MM, Resnick SM.

Neurobiol Aging. 2016 Jul;43:156-63. doi: 10.1016/j.neurobiolaging.2016.04.008. Epub 2016 Apr 21.

27.

Circulating ceramides are inversely associated with cardiorespiratory fitness in participants aged 54-96 years from the Baltimore Longitudinal Study of Aging.

Fabbri E, Yang A, Simonsick EM, Chia CW, Zoli M, Haughey NJ, Mielke MM, Ferrucci L, Coen PM.

Aging Cell. 2016 Oct;15(5):825-31. doi: 10.1111/acel.12491. Epub 2016 May 2.

28.

Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.

Almad AA, Doreswamy A, Gross SK, Richard JP, Huo Y, Haughey N, Maragakis NJ.

Glia. 2016 Jul;64(7):1154-69. doi: 10.1002/glia.22989. Epub 2016 Apr 16.

29.

HIV-associated neurocognitive disorder - pathogenesis and prospects for treatment.

Saylor D, Dickens AM, Sacktor N, Haughey N, Slusher B, Pletnikov M, Mankowski JL, Brown A, Volsky DJ, McArthur JC.

Nat Rev Neurol. 2016 May;12(5):309. doi: 10.1038/nrneurol.2016.53. Epub 2016 Apr 15. No abstract available.

30.

HIV-associated neurocognitive disorder--pathogenesis and prospects for treatment.

Saylor D, Dickens AM, Sacktor N, Haughey N, Slusher B, Pletnikov M, Mankowski JL, Brown A, Volsky DJ, McArthur JC.

Nat Rev Neurol. 2016 Apr;12(4):234-48. doi: 10.1038/nrneurol.2016.27. Epub 2016 Mar 11. Review.

31.

Erratum to: Interaction of Paroxetine with Mitochondrial Proteins Mediates Neuroprotection.

Steiner JP, Bachani M, Wolfson-Stofko B, Lee MH, Wang T, Li G, Li W, Strayer D, Haughey NJ, Nath A.

Neurotherapeutics. 2016 Jan;13(1):237. doi: 10.1007/s13311-015-0406-2. No abstract available.

32.

Interictal, circulating sphingolipids in women with episodic migraine: A case-control study.

Peterlin BL, Mielke MM, Dickens AM, Chatterjee S, Dash P, Alexander G, Vieira RV, Bandaru VV, Dorskind JM, Tietjen GE, Haughey NH.

Neurology. 2015 Oct 6;85(14):1214-23. doi: 10.1212/WNL.0000000000002004. Epub 2015 Sep 9.

33.

Plasma ceramides are elevated in overweight Holstein dairy cows experiencing greater lipolysis and insulin resistance during the transition from late pregnancy to early lactation.

Rico JE, Bandaru VV, Dorskind JM, Haughey NJ, McFadden JW.

J Dairy Sci. 2015 Nov;98(11):7757-70. doi: 10.3168/jds.2015-9519. Epub 2015 Sep 3.

34.

Demographic and clinical variables affecting mid- to late-life trajectories of plasma ceramide and dihydroceramide species.

Mielke MM, Bandaru VV, Han D, An Y, Resnick SM, Ferrucci L, Haughey NJ.

Aging Cell. 2015 Dec;14(6):1014-23. doi: 10.1111/acel.12369. Epub 2015 Jul 20.

35.

Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties.

Figuera-Losada M, Stathis M, Dorskind JM, Thomas AG, Bandaru VV, Yoo SW, Westwood NJ, Rogers GW, McArthur JC, Haughey NJ, Slusher BS, Rojas C.

PLoS One. 2015 May 26;10(5):e0124481. doi: 10.1371/journal.pone.0124481. eCollection 2015.

36.

Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients.

Dickens AM, Anthony DC, Deutsch R, Mielke MM, Claridge TD, Grant I, Franklin D, Rosario D, Marcotte T, Letendre S, McArthur JC, Haughey NJ.

AIDS. 2015 Mar 13;29(5):559-69. doi: 10.1097/QAD.0000000000000580.

37.

Increasing fatty acid oxidation remodels the hypothalamic neurometabolome to mitigate stress and inflammation.

McFadden JW, Aja S, Li Q, Bandaru VV, Kim EK, Haughey NJ, Kuhajda FP, Ronnett GV.

PLoS One. 2014 Dec 26;9(12):e115642. doi: 10.1371/journal.pone.0115642. eCollection 2014.

38.

Quantitative detection of free 24S-hydroxycholesterol, and 27-hydroxycholesterol from human serum.

Bandaru VV, Haughey NJ.

BMC Neurosci. 2014 Dec 24;15:137. doi: 10.1186/s12868-014-0137-z.

39.

Interaction of paroxetine with mitochondrial proteins mediates neuroprotection.

Steiner JP, Bachani M, Wolfson-Stofko B, Lee MH, Wang T, Li G, Li W, Strayer D, Haughey NJ, Nath A.

Neurotherapeutics. 2015 Jan;12(1):200-16. doi: 10.1007/s13311-014-0315-9. Erratum in: Neurotherapeutics. 2016 Jan;13(1):237. Wang, Tonguang [Corrected to Wang, Tongguang].

40.

Impact of minocycline on cerebrospinal fluid markers of oxidative stress, neuronal injury, and inflammation in HIV-seropositive individuals with cognitive impairment.

Sacktor N, Miyahara S, Evans S, Schifitto G, Cohen B, Haughey N, Drewes JL, Graham D, Zink MC, Anderson C, Nath A, Pardo CA, McCarthy S, Hosey L, Clifford D; ACTG A5235 team.

J Neurovirol. 2014 Dec;20(6):620-6. doi: 10.1007/s13365-014-0292-0. Epub 2014 Nov 7.

41.

Factors affecting longitudinal trajectories of plasma sphingomyelins: the Baltimore Longitudinal Study of Aging.

Mielke MM, Bandaru VV, Han D, An Y, Resnick SM, Ferrucci L, Haughey NJ.

Aging Cell. 2015 Feb;14(1):112-21. doi: 10.1111/acel.12275. Epub 2014 Oct 24.

42.

Activation of TRPML1 clears intraneuronal Aβ in preclinical models of HIV infection.

Bae M, Patel N, Xu H, Lee M, Tominaga-Yamanaka K, Nath A, Geiger J, Gorospe M, Mattson MP, Haughey NJ.

J Neurosci. 2014 Aug 20;34(34):11485-503. doi: 10.1523/JNEUROSCI.0210-14.2014.

43.

Ceramide metabolism analysis in a model of binge drinking reveals both neuroprotective and toxic effects of ethanol.

Bae M, Bandaru VV, Patel N, Haughey NJ.

J Neurochem. 2014 Dec;131(5):645-54. doi: 10.1111/jnc.12834. Epub 2014 Aug 21.

44.

Identification of putative biomarkers for HIV-associated neurocognitive impairment in the CSF of HIV-infected patients under cART therapy determined by mass spectrometry.

Bora A, Ubaida Mohien C, Chaerkady R, Chang L, Moxley R 4th, Sacktor N, Haughey N, McArthur JC, Cotter R, Nath A, Graham DR.

J Neurovirol. 2014 Oct;20(5):457-65. doi: 10.1007/s13365-014-0263-5. Epub 2014 Jul 24.

45.

Spinal cord injury causes chronic liver pathology in rats.

Sauerbeck AD, Laws JL, Bandaru VV, Popovich PG, Haughey NJ, McTigue DM.

J Neurotrauma. 2015 Feb 1;32(3):159-69. doi: 10.1089/neu.2014.3497. Epub 2014 Oct 21.

46.

Cerebrospinal fluid sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease.

Mielke MM, Haughey NJ, Bandaru VVR, Zetterberg H, Blennow K, Andreasson U, Johnson SC, Gleason CE, Blazel HM, Puglielli L, Sager MA, Asthana S, Carlsson CM.

Neurobiol Aging. 2014 Nov;35(11):2486-2494. doi: 10.1016/j.neurobiolaging.2014.05.019. Epub 2014 May 27.

47.

Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics.

Vidaurre OG, Haines JD, Katz Sand I, Adula KP, Huynh JL, McGraw CA, Zhang F, Varghese M, Sotirchos E, Bhargava P, Bandaru VV, Pasinetti G, Zhang W, Inglese M, Calabresi PA, Wu G, Miller AE, Haughey NJ, Lublin FD, Casaccia P.

Brain. 2014 Aug;137(Pt 8):2271-86. doi: 10.1093/brain/awu139. Epub 2014 Jun 3. Erratum in: Brain. 2015 Jul;138(Pt 7):e367.

48.

Polyamines: Predictive Biomarker for HIV-Associated Neurocognitive Disorders.

Merali S, Barrero CA, Sacktor NC, Haughey NJ, Datta PK, Langford D, Khalili K.

J AIDS Clin Res. 2014;5(6):1000312.

49.

Ceramides predict verbal memory performance in coronary artery disease patients undertaking exercise: a prospective cohort pilot study.

Saleem M, Bandaru VV, Herrmann N, Swardfager W, Mielke MM, Oh PI, Shammi P, Kiss A, Haughey NJ, Rovinski R, Lanctôt KL.

BMC Geriatr. 2013 Dec 12;13:135. doi: 10.1186/1471-2318-13-135.

50.

A biological perspective of CSF lipids as surrogate markers for cognitive status in HIV.

Haughey NJ, Zhu X, Bandaru VV.

J Neuroimmune Pharmacol. 2013 Dec;8(5):1136-46. doi: 10.1007/s11481-013-9506-0. Epub 2013 Nov 8. Review.

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