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Items: 16

1.

Pharmacokinetics, metabolism, and excretion of linezolid following an oral dose of [(14)C]linezolid to healthy human subjects.

Slatter JG, Stalker DJ, Feenstra KL, Welshman IR, Bruss JB, Sams JP, Johnson MG, Sanders PE, Hauer MJ, Fagerness PE, Stryd RP, Peng GW, Shobe EM.

Drug Metab Dispos. 2001 Aug;29(8):1136-45.

PMID:
11454733
2.

Dapsone activation of CYP2C9-mediated metabolism: evidence for activation of multiple substrates and a two-site model.

Hutzler JM, Hauer MJ, Tracy TS.

Drug Metab Dispos. 2001 Jul;29(7):1029-34. Erratum in: Drug Metab Dispos 2001 Aug;29(8):1171.

PMID:
11408370
3.

Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6.

Voorman RL, Payne NA, Wienkers LC, Hauer MJ, Sanders PE.

Drug Metab Dispos. 2001 Jan;29(1):41-7.

PMID:
11124228
4.

Oxidation of the novel oxazolidinone antibiotic linezolid in human liver microsomes.

Wynalda MA, Hauer MJ, Wienkers LC.

Drug Metab Dispos. 2000 Sep;28(9):1014-7.

PMID:
10950842
5.

Cytochrome P-450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes.

Wienkers LC, Allievi C, Hauer MJ, Wynalda MA.

Drug Metab Dispos. 1999 Nov;27(11):1334-40.

PMID:
10534319
6.

Biotransformation of tirilazad in human: 3. tirilazad A-ring reduction by human liver microsomal 5alpha-reductase type 1 and type 2.

Wienkers LC, Steenwyk RC, Hauer MJ, Fleishaker JC, Pearson PG.

J Pharmacol Exp Ther. 1998 Nov;287(2):583-90.

PMID:
9808684
7.

Human biotransformation of bropirimine. Characterization of the major bropirimine oxidative metabolites formed in vitro.

Wynalda MA, Hauer MJ, Wienkers LC.

Drug Metab Dispos. 1998 Oct;26(10):1048-51.

PMID:
9763414
9.

Quantitative analysis quantitation of 2-n-nonyl-1,3-dioxolane by stable-isotope dilution gas chromatography-mass spectrometry.

Zhong WZ, Sanders PE, Hauer MJ, Vrbanac JJ.

J Chromatogr B Biomed Sci Appl. 1998 Jan 23;705(1):39-45.

PMID:
9498668
10.

Metabolism of a bisphosphonate ester (PNU-91638) in rat.

Slatter JG, Feenstra KL, Hauer MJ, Sanders PE, Vrbanac JJ, Scott G, Speed W.

Xenobiotica. 1997 Oct;27(10):1039-51.

PMID:
9364741
11.

Metabolism of the HIV-1 reverse transcriptase inhibitor delavirdine in mice.

Chang M, Sood VK, Wilson GJ, Kloosterman DA, Sanders PE, Hauer MJ, Zhang W, Branstetter DG.

Drug Metab Dispos. 1997 Jul;25(7):828-39.

PMID:
9224777
12.

Identification of the metabolites of the HIV-1 reverse transcriptase inhibitor delavirdine in monkeys.

Chang M, Sood VK, Kloosterman DA, Hauer MJ, Fagerness PE, Sanders PE, Vrbanac JJ.

Drug Metab Dispos. 1997 Jul;25(7):814-27.

PMID:
9224776
13.

Metabolism of the human immunodeficiency virus type 1 reverse transcriptase inhibitor delavirdine in rats.

Chang M, Sood VK, Wilson GJ, Kloosterman DA, Sanders PE, Hauer MJ, Fagerness PE.

Drug Metab Dispos. 1997 Feb;25(2):228-42.

PMID:
9029054
14.

Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity.

Zhao Z, Koeplinger KA, Padbury GE, Hauer MJ, Bundy GL, Banitt LS, Schwartz TM, Zimmermann DC, Harbach PR, Mayo JK, Aaron CS.

Chem Res Toxicol. 1996 Dec;9(8):1230-9.

PMID:
8951224
15.

In vitro and in vivo biotransformation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-D]pyrimidine (U-89843) in the rat.

Zhao Z, Koeplinger KA, Bundy GL, Banitt LS, Padbury GE, Hauer MJ, Sanders PE.

Drug Metab Dispos. 1996 Feb;24(2):187-98.

PMID:
8742230
16.

Metabolism of the bisphosphonate ester U-91502 in rats.

Slatter JG, Feenstra KL, Hauer MJ, Kloosterman DA, Parton AH, Sanders PE, Scott G, Speed W.

Drug Metab Dispos. 1996 Jan;24(1):65-73.

PMID:
8825192

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