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Items: 1 to 50 of 256

1.

A simple and robust LC-ESI single quadrupole MS-based method to analyze neonicotinoids in honey bee extracts.

Allgaier M, Halder JM, Kittelberger J, Hauer B, Nebel BA.

MethodsX. 2019 Oct 17;6:2484-2491. doi: 10.1016/j.mex.2019.09.038. eCollection 2019.

2.

The Reuniens Nucleus of the Thalamus Has an Essential Role in Coordinating Slow-Wave Activity between Neocortex and Hippocampus.

Hauer BE, Pagliardini S, Dickson CT.

eNeuro. 2019 Oct 17;6(5). pii: ENEURO.0365-19.2019. doi: 10.1523/ENEURO.0365-19.2019. Print 2019 Sep/Oct.

3.

Elimination of Thermomechanical Noise in Piezoelectric Optomechanical Crystals.

Ramp H, Hauer BD, Balram KC, Clark TJ, Srinivasan K, Davis JP.

Phys Rev Lett. 2019 Aug 30;123(9):093603. doi: 10.1103/PhysRevLett.123.093603.

PMID:
31524457
4.

Exploiting Hydrogenophaga pseudoflava for aerobic syngas-based production of chemicals.

Grenz S, Baumann PT, Rückert C, Nebel BA, Siebert D, Schwentner A, Eikmanns BJ, Hauer B, Kalinowski J, Takors R, Blombach B.

Metab Eng. 2019 Sep;55:220-230. doi: 10.1016/j.ymben.2019.07.006. Epub 2019 Jul 15.

PMID:
31319152
5.

First-line tuberculosis drug resistance patterns and associated risk factors in Germany, 2008-2017.

Glasauer S, Altmann D, Hauer B, Brodhun B, Haas W, Perumal N.

PLoS One. 2019 Jun 12;14(6):e0217597. doi: 10.1371/journal.pone.0217597. eCollection 2019.

6.

Oxyfunctionalization of nonsteroidal anti-inflammatory drugs by filamentous-fungi.

Klenk JM, Kontny LH, Escobedo-Hinojosa W, Nebel BA, Hauer B.

J Appl Microbiol. 2019 Sep;127(3):724-738. doi: 10.1111/jam.14342. Epub 2019 Jul 3.

PMID:
31173436
7.

Laboratory evolution reveals the metabolic and regulatory basis of ethylene glycol metabolism by Pseudomonas putida KT2440.

Li WJ, Jayakody LN, Franden MA, Wehrmann M, Daun T, Hauer B, Blank LM, Beckham GT, Klebensberger J, Wierckx N.

Environ Microbiol. 2019 Oct;21(10):3669-3682. doi: 10.1111/1462-2920.14703. Epub 2019 Jul 15.

PMID:
31166064
8.

Assessment of the use and need for an integrated molecular surveillance of tuberculosis: an online survey in Germany.

Sanchini A, Andrés M, Fiebig L, Albrecht S, Hauer B, Haas W.

BMC Public Health. 2019 Mar 18;19(1):321. doi: 10.1186/s12889-019-6631-6.

9.

Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine.

Klenk JM, Fischer MP, Dubiel P, Sharma M, Rowlinson B, Grogan G, Hauer B.

J Biochem. 2019 Jul 1;166(1):51-66. doi: 10.1093/jb/mvz010.

10.

Characterization and structure-guided engineering of the novel versatile terpene monooxygenase CYP109Q5 from Chondromyces apiculatus DSM436.

Klenk JM, Dubiel P, Sharma M, Grogan G, Hauer B.

Microb Biotechnol. 2019 Mar;12(2):377-391. doi: 10.1111/1751-7915.13354. Epub 2018 Dec 27.

11.

Directed Evolution Empowered Redesign of Natural Proteins for the Sustainable Production of Chemicals and Pharmaceuticals.

Bornscheuer UT, Hauer B, Jaeger KE, Schwaneberg U.

Angew Chem Int Ed Engl. 2019 Jan 2;58(1):36-40. doi: 10.1002/anie.201812717. Epub 2018 Dec 6. Review.

PMID:
30520553
12.

Unlocked potential of dynamic elements in protein structures: channels and loops.

Kreß N, Halder JM, Rapp LR, Hauer B.

Curr Opin Chem Biol. 2018 Dec;47:109-116. doi: 10.1016/j.cbpa.2018.09.010. Epub 2018 Oct 4. Review.

PMID:
30292890
13.

Asymmetric Enzymatic Hydration of Unactivated, Aliphatic Alkenes.

Demming RM, Hammer SC, Nestl BM, Gergel S, Fademrecht S, Pleiss J, Hauer B.

Angew Chem Int Ed Engl. 2019 Jan 2;58(1):173-177. doi: 10.1002/anie.201810005. Epub 2018 Nov 30.

14.

Hyperoxia enhances slow-wave forebrain states in urethane-anesthetized and naturally sleeping rats.

Hauer BE, Negash B, Chan K, Vuong W, Colbourne F, Pagliardini S, Dickson CT.

J Neurophysiol. 2018 Oct 1;120(4):1505-1515. doi: 10.1152/jn.00373.2018. Epub 2018 Jun 27.

15.

Engineering Pseudomonas putida KT2440 for efficient ethylene glycol utilization.

Franden MA, Jayakody LN, Li WJ, Wagner NJ, Cleveland NS, Michener WE, Hauer B, Blank LM, Wierckx N, Klebensberger J, Beckham GT.

Metab Eng. 2018 Jul;48:197-207. doi: 10.1016/j.ymben.2018.06.003. Epub 2018 Jun 7.

16.

Biocatalyst Screening with a Twist: Application of Oxygen Sensors Integrated in Microchannels for Screening Whole Cell Biocatalyst Variants.

Fernandes AC, Halder JM, Nestl BM, Hauer B, Gernaey KV, Krühne U.

Bioengineering (Basel). 2018 Apr 9;5(2). pii: E30. doi: 10.3390/bioengineering5020030.

17.

Find and treat or find and lose? Tuberculosis treatment outcomes among screened newly arrived asylum seekers in Germany 2002 to 2014.

Kuehne A, Hauer B, Brodhun B, Haas W, Fiebig L.

Euro Surveill. 2018 Mar;23(11). doi: 10.2807/1560-7917.ES.2018.23.11.17-00042.

18.

(De)hydratases-recent developments and future perspectives.

Demming RM, Fischer MP, Schmid J, Hauer B.

Curr Opin Chem Biol. 2018 Apr;43:43-50. doi: 10.1016/j.cbpa.2017.10.030. Epub 2017 Nov 20. Review.

PMID:
29156448
19.

Magnetic actuation and feedback cooling of a cavity optomechanical torque sensor.

Kim PH, Hauer BD, Clark TJ, Fani Sani F, Freeman MR, Davis JP.

Nat Commun. 2017 Nov 7;8(1):1355. doi: 10.1038/s41467-017-01380-z.

20.

Tuberculosis screening in asylum seekers in Germany, 2015: characteristics of cases and yield.

Fiebig L, Hauer B, Andrés M, Haas W.

Eur Respir J. 2017 Oct 26;50(4). pii: 1602550. doi: 10.1183/13993003.02550-2016. Print 2017 Oct. No abstract available.

21.

Modulating proposed electron transfer pathways in P450BM3 led to improved activity and coupling efficiency.

Darimont D, Weissenborn MJ, Nebel BA, Hauer B.

Bioelectrochemistry. 2018 Feb;119:119-123. doi: 10.1016/j.bioelechem.2017.08.009. Epub 2017 Sep 18.

PMID:
28965071
22.

Enzymatic Addition of Alcohols to Terpenes by Squalene Hopene Cyclase Variants.

Kühnel LC, Nestl BM, Hauer B.

Chembiochem. 2017 Nov 16;18(22):2222-2225. doi: 10.1002/cbic.201700449. Epub 2017 Oct 2.

PMID:
28898524
23.

[Tuberculosis Guideline for Adults - Guideline for Diagnosis and Treatment of Tuberculosis including LTBI Testing and Treatment of the German Central Committee (DZK) and the German Respiratory Society (DGP)].

Schaberg T, Bauer T, Brinkmann F, Diel R, Feiterna-Sperling C, Haas W, Hartmann P, Hauer B, Heyckendorf J, Lange C, Nienhaus A, Otto-Knapp R, Priwitzer M, Richter E, Rumetshofer R, Schenkel K, Schoch OD, Schönfeld N, Stahlmann R.

Pneumologie. 2017 Jun;71(6):325-397. doi: 10.1055/s-0043-105954. Epub 2017 Jun 26. German.

PMID:
28651293
24.

Editorial overview: Beyond native biocatalysts and natural biotransformations.

Hauer B, Lutz S.

Curr Opin Chem Biol. 2017 Apr;37:iv-v. doi: 10.1016/j.cbpa.2017.04.006. No abstract available.

PMID:
28456328
25.

Contact investigation after a fatal case of extensively drug-resistant tuberculosis (XDR-TB) in an aircraft, Germany, July 2013.

An der Heiden M, Hauer B, Fiebig L, Glaser-Paschke G, Stemmler M, Simon C, Rüsch-Gerdes S, Gilsdorf A, Haas W.

Euro Surveill. 2017 Mar 23;22(12). pii: 30493. doi: 10.2807/1560-7917.ES.2017.22.12.30493.

26.

Treatment outcome in children with nontuberculous mycobacterial lymphadenitis: A retrospective follow-up study.

Reuss A, Drzymala S, Hauer B, von Kries R, Haas W.

Int J Mycobacteriol. 2017 Jan-Mar;6(1):76-82. doi: 10.4103/2212-5531.201898.

27.

Enantioselective Reduction of Citral Isomers in NCR Ene Reductase: Analysis of an Active-Site Mutant Library.

Kress N, Rapp J, Hauer B.

Chembiochem. 2017 Apr 18;18(8):717-720. doi: 10.1002/cbic.201700011. Epub 2017 Mar 9.

PMID:
28176464
28.

A joint cross-border investigation of a cluster of multidrug-resistant tuberculosis in Austria, Romania and Germany in 2014 using classic, genotyping and whole genome sequencing methods: lessons learnt.

Fiebig L, Kohl TA, Popovici O, Mühlenfeld M, Indra A, Homorodean D, Chiotan D, Richter E, Rüsch-Gerdes S, Schmidgruber B, Beckert P, Hauer B, Niemann S, Allerberger F, Haas W.

Euro Surveill. 2017 Jan 12;22(2). pii: 30439. doi: 10.2807/1560-7917.ES.2017.22.2.30439.

29.

The self-sufficient P450 RhF expressed in a whole cell system selectively catalyses the 5-hydroxylation of diclofenac.

Klenk JM, Nebel BA, Porter JL, Kulig JK, Hussain SA, Richter SM, Tavanti M, Turner NJ, Hayes MA, Hauer B, Flitsch SL.

Biotechnol J. 2017 Mar;12(3). doi: 10.1002/biot.201600520. Epub 2017 Feb 8.

PMID:
28098428
30.

Structural and functional insights into asymmetric enzymatic dehydration of alkenols.

Nestl BM, Geinitz C, Popa S, Rizek S, Haselbeck RJ, Stephen R, Noble MA, Fischer MP, Ralph EC, Hau HT, Man H, Omar M, Turkenburg JP, van Dien S, Culler SJ, Grogan G, Hauer B.

Nat Chem Biol. 2017 Mar;13(3):275-281. doi: 10.1038/nchembio.2271. Epub 2017 Jan 9.

31.

Approaching the standard quantum limit of mechanical torque sensing.

Kim PH, Hauer BD, Doolin C, Souris F, Davis JP.

Nat Commun. 2016 Oct 20;7:13165. doi: 10.1038/ncomms13165.

32.

Track F. Biosensors and Bioanalytics.

Holz P, Hauer B, Brandenburg A, Wadle S, Zehnle S, Keller M, Möller R, Koger B.

Biomed Tech (Berl). 2016 Sep 1;61(s1):33-47. doi: 10.1515/bmt-2016-5004. No abstract available.

PMID:
27682686
33.

Squalene-hopene cyclases-evolution, dynamics and catalytic scope.

Syrén PO, Henche S, Eichler A, Nestl BM, Hauer B.

Curr Opin Struct Biol. 2016 Dec;41:73-82. doi: 10.1016/j.sbi.2016.05.019. Epub 2016 Jun 20. Review.

PMID:
27336183
34.

Semirational Protein Engineering of CYP153AM.aq. -CPRBM3 for Efficient Terminal Hydroxylation of Short- to Long-Chain Fatty Acids.

Notonier S, Gricman Ł, Pleiss J, Hauer B.

Chembiochem. 2016 Aug 17;17(16):1550-7. doi: 10.1002/cbic.201600207. Epub 2016 Jul 1.

PMID:
27251775
35.

Production of ω-hydroxy octanoic acid with Escherichia coli.

Kirtz M, Klebensberger J, Otte KB, Richter SM, Hauer B.

J Biotechnol. 2016 Jul 20;230:30-3. doi: 10.1016/j.jbiotec.2016.05.017. Epub 2016 May 13.

PMID:
27184430
36.

Expanding an Efficient, Electrically Driven and CNT-Tagged P450 System into the Third Dimension: A Nanowired CNT-Containing and Enzyme-Stabilising 3 D Sol-Gel Electrode.

Llaudet EC, Darimont D, Samba R, Matiychyn I, Stelzle M, Weissenborn MJ, Hauer B.

Chembiochem. 2016 Jul 15;17(14):1367-73. doi: 10.1002/cbic.201600173. Epub 2016 Jun 17.

PMID:
27158934
37.

Cultivation and purification of two stereoselective imine reductases from Streptosporangium roseum and Paenibacillus elgii.

Lenz M, Scheller PN, Richter SM, Hauer B, Nestl BM.

Protein Expr Purif. 2017 May;133:199-204. doi: 10.1016/j.pep.2016.05.003. Epub 2016 May 5.

PMID:
27157442
38.

Advancing global programmatic management of latent tuberculosis infection for at risk populations.

Getahun H, Matteelli A, Abubakar I, Hauer B, Pontali E, Migliori GB.

Eur Respir J. 2016 May;47(5):1327-30. doi: 10.1183/13993003.00449-2016. No abstract available.

39.

Whole-cell microtiter plate screening assay for terminal hydroxylation of fatty acids by P450s.

Weissenborn MJ, Notonier S, Lang SL, Otte KB, Herter S, Turner NJ, Flitsch SL, Hauer B.

Chem Commun (Camb). 2016 May 4;52(36):6158-61. doi: 10.1039/c6cc01749e. Epub 2016 Apr 14.

PMID:
27074906
40.

Recommendations of the German Central Committee against Tuberculosis (DZK) and the German Respiratory Society (DGP) for the Diagnosis and Treatment of Non-tuberculous Mycobacterioses.

Schoenfeld N, Haas W, Richter E, Bauer T, Boes L, Castell S, Hauer B, Magdorf K, Matthiessen W, Mauch H, Reuss A, Schenkel K, Ruesch-Gerdes S, Zabel P, Dalhoff K, Schaberg T, Loddenkemper R.

Pneumologie. 2016 Apr;70(4):250-76. doi: 10.1055/s-0041-111494. Epub 2016 Apr 11. Review.

41.

Loop-Grafted Old Yellow Enzymes in the Bienzymatic Cascade Reduction of Allylic Alcohols.

Reich S, Nestl BM, Hauer B.

Chembiochem. 2016 Apr 1;17(7):561-5. doi: 10.1002/cbic.201500604. Epub 2016 Feb 23.

PMID:
27037735
42.

Accelerated Nucleation of Hydroxyapatite Using an Engineered Hydrophobin Fusion Protein.

Melcher M, Facey SJ, Henkes TM, Subkowski T, Hauer B.

Biomacromolecules. 2016 May 9;17(5):1716-26. doi: 10.1021/acs.biomac.6b00135. Epub 2016 Apr 5.

PMID:
27010648
43.

Exploring the detection limits of infrared near-field microscopy regarding small buried structures and pushing them by exploiting superlens-related effects.

Jung L, Hauer B, Li P, Bornhöfft M, Mayer J, Taubner T.

Opt Express. 2016 Mar 7;24(5):4431-4441. doi: 10.1364/OE.24.004431.

PMID:
29092272
44.

Identification of imine reductase-specific sequence motifs.

Fademrecht S, Scheller PN, Nestl BM, Hauer B, Pleiss J.

Proteins. 2016 May;84(5):600-10. doi: 10.1002/prot.25008. Epub 2016 Mar 6.

PMID:
26857686
45.

Tuberculosis treatment outcome in the European Union and European Economic Area: an analysis of surveillance data from 2002-2011.

Karo B, Hauer B, Hollo V, van der Werf MJ, Fiebig L, Haas W.

Euro Surveill. 2015;20(49). doi: 10.2807/1560-7917.ES.2015.20.49.30087. Erratum in: Euro Surveill. 2015;20(50). doi: 10.2807/1560-7917.ES.2015.20.50.30092.

46.

A Monolithic Hybrid Cellulose-2.5-Acetate/Polymer Bioreactor for Biocatalysis under Continuous Liquid-Liquid Conditions Using a Supported Ionic Liquid Phase.

Sandig B, Michalek L, Vlahovic S, Antonovici M, Hauer B, Buchmeiser MR.

Chemistry. 2015 Oct 26;21(44):15835-42. doi: 10.1002/chem.201501618. Epub 2015 Sep 10.

PMID:
26493884
47.

Tuberculosis in Germany: a declining trend coming to an end?

Fiebig L, Hauer B, Brodhun B, Altmann D, Haas W.

Eur Respir J. 2016 Feb;47(2):667-70. doi: 10.1183/13993003.01410-2015. Epub 2015 Oct 22. No abstract available.

48.

Molecular Genetic and Crystal Structural Analysis of 1-(4-Hydroxyphenyl)-Ethanol Dehydrogenase from 'Aromatoleum aromaticum' EbN1.

Büsing I, Höffken HW, Breuer M, Wöhlbrand L, Hauer B, Rabus R.

J Mol Microbiol Biotechnol. 2015;25(5):327-39. doi: 10.1159/000439113. Epub 2015 Oct 22.

49.

Mutations improving production and secretion of extracellular lipase by Burkholderia glumae PG1.

Knapp A, Voget S, Gao R, Zaburannyi N, Krysciak D, Breuer M, Hauer B, Streit WR, Müller R, Daniel R, Jaeger KE.

Appl Microbiol Biotechnol. 2016 Feb;100(3):1265-1273. doi: 10.1007/s00253-015-7041-z. Epub 2015 Oct 17.

50.

Process limitations of a whole-cell P450 catalyzed reaction using a CYP153A-CPR fusion construct expressed in Escherichia coli.

Lundemo MT, Notonier S, Striedner G, Hauer B, Woodley JM.

Appl Microbiol Biotechnol. 2016 Feb;100(3):1197-1208. doi: 10.1007/s00253-015-6999-x. Epub 2015 Oct 2.

PMID:
26432459

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