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Items: 18

1.

CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.

Hoffman GE, Bendl J, Voloudakis G, Montgomery KS, Sloofman L, Wang YC, Shah HR, Hauberg ME, Johnson JS, Girdhar K, Song L, Fullard JF, Kramer R, Hahn CG, Gur R, Marenco S, Lipska BK, Lewis DA, Haroutunian V, Hemby S, Sullivan P, Akbarian S, Chess A, Buxbaum JD, Crawford GE, Domenici E, Devlin B, Sieberts SK, Peters MA, Roussos P.

Sci Data. 2019 Sep 24;6(1):180. doi: 10.1038/s41597-019-0183-6.

2.

Identification of common genetic risk variants for autism spectrum disorder.

Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, Nærland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnström K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos P, Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, Børglum AD.

Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038/s41588-019-0344-8. Epub 2019 Feb 25.

3.

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.

Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, Gandal M, Goldstein JI, Grasby KL, Grove J, Gudmundsson OO, Hansen CS, Hauberg ME, Hollegaard MV, Howrigan DP, Huang H, Maller JB, Martin AR, Martin NG, Moran J, Pallesen J, Palmer DS, Pedersen CB, Pedersen MG, Poterba T, Poulsen JB, Ripke S, Robinson EB, Satterstrom FK, Stefansson H, Stevens C, Turley P, Walters GB, Won H, Wright MJ; ADHD Working Group of the Psychiatric Genomics Consortium (PGC); Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium; 23andMe Research Team, Andreassen OA, Asherson P, Burton CL, Boomsma DI, Cormand B, Dalsgaard S, Franke B, Gelernter J, Geschwind D, Hakonarson H, Haavik J, Kranzler HR, Kuntsi J, Langley K, Lesch KP, Middeldorp C, Reif A, Rohde LA, Roussos P, Schachar R, Sklar P, Sonuga-Barke EJS, Sullivan PF, Thapar A, Tung JY, Waldman ID, Medland SE, Stefansson K, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Daly MJ, Faraone SV, Børglum AD, Neale BM.

Nat Genet. 2019 Jan;51(1):63-75. doi: 10.1038/s41588-018-0269-7. Epub 2018 Nov 26.

4.

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.

Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, Mahajan M, Mangravite LM, Dammer EB, Duong DM, Lah JJ, Seyfried NT, Levey AI, Buxbaum JD, Ehrlich M, Gandy S, Katsel P, Haroutunian V, Schadt E, Zhang B.

Sci Data. 2018 Sep 11;5:180185. doi: 10.1038/sdata.2018.185.

5.

Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome.

Girdhar K, Hoffman GE, Jiang Y, Brown L, Kundakovic M, Hauberg ME, Francoeur NJ, Wang YC, Shah H, Kavanagh DH, Zharovsky E, Jacobov R, Wiseman JR, Park R, Johnson JS, Kassim BS, Sloofman L, Mattei E, Weng Z, Sieberts SK, Peters MA, Harris BT, Lipska BK, Sklar P, Roussos P, Akbarian S.

Nat Neurosci. 2018 Aug;21(8):1126-1136. doi: 10.1038/s41593-018-0187-0. Epub 2018 Jul 23.

6.

Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.

Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P.

Hum Mol Genet. 2018 Jun 29. doi: 10.1093/hmg/ddy229. [Epub ahead of print] No abstract available.

PMID:
29982455
7.

An atlas of chromatin accessibility in the adult human brain.

Fullard JF, Hauberg ME, Bendl J, Egervari G, Cirnaru MD, Reach SM, Motl J, Ehrlich ME, Hurd YL, Roussos P.

Genome Res. 2018 Aug;28(8):1243-1252. doi: 10.1101/gr.232488.117. Epub 2018 Jun 26.

8.

Brain Cell Type Specific Gene Expression and Co-expression Network Architectures.

McKenzie AT, Wang M, Hauberg ME, Fullard JF, Kozlenkov A, Keenan A, Hurd YL, Dracheva S, Casaccia P, Roussos P, Zhang B.

Sci Rep. 2018 Jun 11;8(1):8868. doi: 10.1038/s41598-018-27293-5.

9.

Differential activity of transcribed enhancers in the prefrontal cortex of 537 cases with schizophrenia and controls.

Hauberg ME, Fullard JF, Zhu L, Cohain AT, Giambartolomei C, Misir R, Reach S, Johnson JS, Wang M, Mattheisen M, Børglum AD, Zhang B, Sieberts SK, Peters MA, Domenici E, Schadt EE, Devlin B, Sklar P, Roeder K, Roussos P; CommonMind Consortium.

Mol Psychiatry. 2019 Nov;24(11):1685-1695. doi: 10.1038/s41380-018-0059-8. Epub 2018 May 8.

10.

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells.

Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, Cagney G, Rapoport J, Gage FH, Dudley JT, Sklar P, Mattheisen M, Cotter D, Fang G, Brennand KJ.

Cell Rep. 2017 Sep 5;20(10):2525. doi: 10.1016/j.celrep.2017.08.073. No abstract available.

11.

Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression.

Hauberg ME, Zhang W, Giambartolomei C, Franzén O, Morris DL, Vyse TJ, Ruusalepp A; CommonMind Consortium, Sklar P, Schadt EE, Björkegren JLM, Roussos P.

Am J Hum Genet. 2017 Jul 6;101(1):157. doi: 10.1016/j.ajhg.2017.06.003. No abstract available.

12.

Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression.

Hauberg ME, Zhang W, Giambartolomei C, Franzén O, Morris DL, Vyse TJ, Ruusalepp A; CommonMind Consortium, Sklar P, Schadt EE, Björkegren JLM, Roussos P.

Am J Hum Genet. 2017 Jun 1;100(6):885-894. doi: 10.1016/j.ajhg.2017.04.016. Epub 2017 May 25. Erratum in: Am J Hum Genet. 2017 Jul 6;101(1):157.

13.

Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.

Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P.

Hum Mol Genet. 2017 May 15;26(10):1942-1951. doi: 10.1093/hmg/ddx103.

14.

The Schizophrenia-Associated BRD1 Gene Regulates Behavior, Neurotransmission, and Expression of Schizophrenia Risk Enriched Gene Sets in Mice.

Qvist P, Christensen JH, Vardya I, Rajkumar AP, Mørk A, Paternoster V, Füchtbauer EM, Pallesen J, Fryland T, Dyrvig M, Hauberg ME, Lundsberg B, Fejgin K, Nyegaard M, Jensen K, Nyengaard JR, Mors O, Didriksen M, Børglum AD.

Biol Psychiatry. 2017 Jul 1;82(1):62-76. doi: 10.1016/j.biopsych.2016.08.037. Epub 2016 Sep 15.

PMID:
27837920
15.

Schizophrenia risk variants affecting microRNA function and site-specific regulation of NT5C2 by miR-206.

Hauberg ME, Holm-Nielsen MH, Mattheisen M, Askou AL, Grove J, Børglum AD, Corydon TJ.

Eur Neuropsychopharmacol. 2016 Sep;26(9):1522-1526. doi: 10.1016/j.euroneuro.2016.06.014. Epub 2016 Jul 11.

PMID:
27424800
16.

Identification of the BRD1 interaction network and its impact on mental disorder risk.

Fryland T, Christensen JH, Pallesen J, Mattheisen M, Palmfeldt J, Bak M, Grove J, Demontis D, Blechingberg J, Ooi HS, Nyegaard M, Hauberg ME, Tommerup N, Gregersen N, Mors O, Corydon TJ, Nielsen AL, Børglum AD.

Genome Med. 2016 May 3;8(1):53. doi: 10.1186/s13073-016-0308-x.

17.

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells.

Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, Cagney G, Rapoport J, Gage FH, Dudley JT, Sklar P, Mattheisen M, Cotter D, Fang G, Brennand KJ.

Cell Rep. 2016 May 3;15(5):1024-1036. doi: 10.1016/j.celrep.2016.03.090. Epub 2016 Apr 21. Erratum in: Cell Rep. 2017 Sep 5;20(10):2525.

18.

Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants.

Hauberg ME, Roussos P, Grove J, Børglum AD, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium.

JAMA Psychiatry. 2016 Apr;73(4):369-77. doi: 10.1001/jamapsychiatry.2015.3018.

PMID:
26963595

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