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Hypomyelinating leukodystrophy-associated mutation of RARS leads it to the lysosome, inhibiting oligodendroglial morphological differentiation.

Matsumoto N, Watanabe N, Iibe N, Tatsumi Y, Hattori K, Takeuchi Y, Oizumi H, Ohbuchi K, Torii T, Miyamoto Y, Yamauchi J.

Biochem Biophys Rep. 2019 Nov 7;20:100705. doi: 10.1016/j.bbrep.2019.100705. eCollection 2019 Dec.


Two ANGUSTIFOLIA genes regulate gametophore and sporophyte development in Physcomitrella patens.

Hashida Y, Takechi K, Abiru T, Yabe N, Nagase H, Hattori K, Takio S, Sato Y, Hasebe M, Tsukaya H, Takano H.

Plant J. 2019 Nov 1. doi: 10.1111/tpj.14592. [Epub ahead of print]


Reduced plasma orexin-A levels in patients with bipolar disorder.

Tsuchimine S, Hattori K, Ota M, Hidese S, Teraishi T, Sasayama D, Hori H, Noda T, Yoshida S, Yoshida F, Kunugi H.

Neuropsychiatr Dis Treat. 2019 Aug 6;15:2221-2230. doi: 10.2147/NDT.S209023. eCollection 2019.


Altered polyunsaturated fatty acid levels in relation to proinflammatory cytokines, fatty acid desaturase genotype, and diet in bipolar disorder.

Koga N, Ogura J, Yoshida F, Hattori K, Hori H, Aizawa E, Ishida I, Kunugi H.

Transl Psychiatry. 2019 Aug 27;9(1):208. doi: 10.1038/s41398-019-0536-0.


Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses.

Nagai M, Noguchi R, Takahashi D, Morikawa T, Koshida K, Komiyama S, Ishihara N, Yamada T, Kawamura YI, Muroi K, Hattori K, Kobayashi N, Fujimura Y, Hirota M, Matsumoto R, Aoki R, Tamura-Nakano M, Sugiyama M, Katakai T, Sato S, Takubo K, Dohi T, Hase K.

Cell. 2019 Aug 22;178(5):1072-1087.e14. doi: 10.1016/j.cell.2019.07.047.


A Case of Primary Colonic Signet Ring Cell Carcinoma in a Young Man which Preoperatively Mimicked Phlebosclerotic Colitis.

Watanabe A, Kadowaki Y, Hattori K, Ohmori M, Tsukayama H, Kubota N, Okumoto T, Ishido N, Okino T.

Acta Med Okayama. 2019 Aug;73(4):361-365. doi: 10.18926/AMO/56939.


Mutations found in cell-free DNAs of patients with malignant lymphoma at remission can derive from clonal hematopoiesis.

Suehara Y, Sakata-Yanagimoto M, Hattori K, Kusakabe M, Nanmoku T, Sato T, Noguchi M, Chiba S.

Cancer Sci. 2019 Oct;110(10):3375-3381. doi: 10.1111/cas.14176. Epub 2019 Sep 12.


Trait Loci Mapping and CSF Proteome.

Sasayama D, Hattori K, Kunugi H.

Methods Mol Biol. 2019;2044:365-376. doi: 10.1007/978-1-4939-9706-0_24.


A descriptive research: Exclusion from submitted clinical data package in the review process of new drug approval due to GCP violation in Japan.

Asada R, Yoshimura K, Hattori K, Nonaka Y, Kasai H, Shimizu S.

Contemp Clin Trials Commun. 2019 Jul 19;15:100416. doi: 10.1016/j.conctc.2019.100416. eCollection 2019 Sep.


ASP1126, a Novel Sphingosine-1-Phosphate-Selective Agonist With a Favorable Safety Profile, Prolongs Allograft Survival in Rats and Nonhuman Primates in Combination With Tacrolimus With a Broad Safety Margin for Bradycardia.

Okimoto A, Yamamoto R, Hirose J, Shimatani K, Koshika T, Maeda M, Hattori K, Morokata T.

Transplant Proc. 2019 Jul - Aug;51(6):2081-2098. doi: 10.1016/j.transproceed.2019.05.012.


Synthesis and SAR Study of Carbamoyl Pyridone Bicycle Derivatives as Potent Inhibitors of Influenza Cap-dependent Endonuclease.

Miyagawa M, Akiyama T, Taoda Y, Takaya K, Takahashi-Kageyama C, Tomita K, Yasuo K, Hattori K, Shano S, Yoshida R, Shishido T, Yoshinaga T, Sato A, Kawai M.

J Med Chem. 2019 Sep 12;62(17):8101-8114. doi: 10.1021/acs.jmedchem.9b00861. Epub 2019 Aug 19.


Generalized self-consistent reservoir model for normal and anomalous heat transport in quantum harmonic chains.

Hattori K, Yoshikawa M.

Phys Rev E. 2019 Jun;99(6-1):062104. doi: 10.1103/PhysRevE.99.062104.


Ionization-Induced π → H Site Switching in Resorcinol-Arn (n = 1 and 2) Clusters Probed by Infrared Spectroscopy.

Miyazaki M, Chatterjee K, Hattori K, Otsuka R, Ishiuchi SI, Dopfer O, Fujii M.

J Phys Chem A. 2019 Aug 15;123(32):6828-6839. doi: 10.1021/acs.jpca.9b04460. Epub 2019 Aug 1.


Refractory Sjögren's syndrome myelopathy successfully treated with subcutaneous tocilizumab: A case report.

Ishikawa Y, Hattori K, Ishikawa J, Fujiwara M, Kita Y.

Medicine (Baltimore). 2019 Jul;98(27):e16285. doi: 10.1097/MD.0000000000016285.


The first Japanese nationwide multicenter study of BRCA mutation testing in ovarian cancer: CHARacterizing the cross-sectionaL approach to Ovarian cancer geneTic TEsting of BRCA (CHARLOTTE).

Enomoto T, Aoki D, Hattori K, Jinushi M, Kigawa J, Takeshima N, Tsuda H, Watanabe Y, Yoshihara K, Sugiyama T.

Int J Gynecol Cancer. 2019 Jul;29(6):1043-1049. doi: 10.1136/ijgc-2019-000384.


Lysophosphatidic acid levels in cerebrospinal fluid and plasma samples in patients with major depressive disorder.

Gotoh L, Yamada M, Hattori K, Sasayama D, Noda T, Yoshida S, Kunugi H, Yamada M.

Heliyon. 2019 May 16;5(5):e01699. doi: 10.1016/j.heliyon.2019.e01699. eCollection 2019 May.


Null mutation of the endothelin receptor type B gene causes embryonic death in the GK rat.

Wang J, Dang R, Miyasaka Y, Hattori K, Torigoe D, Okamura T, Tag-Ei-Din-Hassan HT, Morimatsu M, Mashimo T, Agui T.

PLoS One. 2019 Jun 6;14(6):e0217132. doi: 10.1371/journal.pone.0217132. eCollection 2019.


Global Analysis of Transcriptional Expression in Mice Exposed to Intermediate Frequency Magnetic Fields Utilized for Wireless Power Transfer Systems.

Ohtani S, Ushiyama A, Maeda M, Wada K, Suzuki Y, Hattori K, Kunugita N, Ishii K.

Int J Environ Res Public Health. 2019 May 25;16(10). pii: E1851. doi: 10.3390/ijerph16101851.


A Case of Eosinophilic Chronic Rhinosinusitis Associated with Choroidal Folds and Ocular Motility Disorder.

Ikeda M, Iwahashi C, Hirai T, Hattori K, Mitarai K.

Case Rep Ophthalmol. 2019 Feb 28;10(1):89-94. doi: 10.1159/000497270. eCollection 2019 Jan-Apr.


High rate filtration for local treatment of combined sewer overflow.

Helness H, Sun C, Damman S, Ahmadi M, Raspati G, Bjerkelund V, Moldestad G, Hattori K, Kato T, Ando N.

Water Sci Technol. 2019 Mar;79(6):1206-1213. doi: 10.2166/wst.2019.121.


VEGF Receptor 1-Expressing Macrophages Recruited from Bone Marrow Enhances Angiogenesis in Endometrial Tissues.

Sekiguchi K, Ito Y, Hattori K, Inoue T, Hosono K, Honda M, Numao A, Amano H, Shibuya M, Unno N, Majima M.

Sci Rep. 2019 May 7;9(1):7037. doi: 10.1038/s41598-019-43185-8.


Cerebrospinal fluid BDNF pro-peptide levels in major depressive disorder and schizophrenia.

Mizui T, Hattori K, Ishiwata S, Hidese S, Yoshida S, Kunugi H, Kojima M.

J Psychiatr Res. 2019 Jun;113:190-198. doi: 10.1016/j.jpsychires.2019.03.024. Epub 2019 Mar 26.


Surgical embolectomy for paradoxical cerebral embolism with massive pulmonary embolism.

Hattori K, Daitoku K, Taniguchi S, Fukuda I.

Gen Thorac Cardiovasc Surg. 2019 Apr 6. doi: 10.1007/s11748-019-01087-6. [Epub ahead of print]


Quantitative evaluation of stress in Japanese anesthesiology residents based on heart rate variability and psychological testing.

Hattori K, Asamoto M, Otsuji M, Ito N, Kasahara S, Hashimoto Y, Yamada Y.

J Clin Monit Comput. 2019 Apr 1. doi: 10.1007/s10877-019-00305-z. [Epub ahead of print]


A polymorphism of the methylenetetrahydrofolate reductase gene confers susceptibility to schizophrenia and related brain changes.

Ota M, Sato N, Yoshida F, Hattori K, Hidese S, Teraishi T, Kunugi H.

Schizophr Res. 2019 Jun;208:462-464. doi: 10.1016/j.schres.2019.03.002. Epub 2019 Mar 7. No abstract available.


Staged coil embolization after thoracic endovascular stent grafting for aneurysmal chronic type B aortic dissection: A case report.

Nakayama T, Hattori K, Hashizume T, Asano M.

SAGE Open Med Case Rep. 2019 Feb 12;7:2050313X19828903. doi: 10.1177/2050313X19828903. eCollection 2019.


Regulatory Role of GRK2 in the TLR Signaling-Mediated iNOS Induction Pathway in Microglial Cells.

Palikhe S, Ohashi W, Sakamoto T, Hattori K, Kawakami M, Andoh T, Yamazaki H, Hattori Y.

Front Pharmacol. 2019 Feb 4;10:59. doi: 10.3389/fphar.2019.00059. eCollection 2019.


Defective neuronal and oligodendroglial differentiation by FTD3- and ALS17-associated Ile29-to-Val mutation of CHMP2B.

Yamawaki M, Akiba M, Matsumoto N, Watanabe N, Hattori K, Takeuchi Y, Morimoto T, Oizumi H, Ohbuchi K, Miyamoto Y, Yamauchi J.

Mol Genet Metab Rep. 2019 Feb 2;19:100458. doi: 10.1016/j.ymgmr.2019.100458. eCollection 2019 Jun. No abstract available.


Reduced Serum and Cerebrospinal Fluid Levels of Autotaxin in Major Depressive Disorder.

Itagaki K, Takebayashi M, Abe H, Shibasaki C, Kajitani N, Okada-Tsuchioka M, Hattori K, Yoshida S, Kunugi H, Yamawaki S.

Int J Neuropsychopharmacol. 2019 Apr 1;22(4):261-269. doi: 10.1093/ijnp/pyz005.


Bifidobacterium and Lactobacillus Counts in the Gut Microbiota of Patients With Bipolar Disorder and Healthy Controls.

Aizawa E, Tsuji H, Asahara T, Takahashi T, Teraishi T, Yoshida S, Koga N, Hattori K, Ota M, Kunugi H.

Front Psychiatry. 2019 Jan 18;9:730. doi: 10.3389/fpsyt.2018.00730. eCollection 2018.


Levels of lysophosphatidic acid in cerebrospinal fluid and plasma of patients with schizophrenia.

Gotoh L, Yamada M, Hattori K, Sasayama D, Noda T, Yoshida S, Kunugi H, Yamada M.

Psychiatry Res. 2019 Mar;273:331-335. doi: 10.1016/j.psychres.2019.01.052. Epub 2019 Jan 15.


The relationship between the Wechsler Memory Scale-Revised scores and whole-brain structure in patients with schizophrenia and healthy individuals.

Hidese S, Ota M, Hori H, Matsuo J, Ishida I, Hiraishi M, Teraishi T, Hattori K, Kunugi H.

Cogn Neuropsychiatry. 2019 Jan;24(1):80-91. doi: 10.1080/13546805.2019.1570100. Epub 2019 Jan 24.


Association Between Motor-Evoked Potentials and Spinal Cord Damage Diagnosed With Magnetic Resonance Imaging After Thoracoabdominal and Descending Aortic Aneurysm Repair.

Hattori K, Yoshitani K, Kato S, Kawaguchi M, Kawamata M, Kakinohana M, Yamada Y, Yamakage M, Nishiwaki K, Izumi S, Yoshikawa Y, Mori Y, Hasegawa K, Onishi Y.

J Cardiothorac Vasc Anesth. 2019 Jul;33(7):1835-1842. doi: 10.1053/j.jvca.2018.12.004. Epub 2018 Dec 5.


Prominence of nestin-expressing Schwann cells in bone marrow of patients with myelodysplastic syndromes with severe fibrosis.

Cao-Sy L, Obara N, Sakamoto T, Kato T, Hattori K, Sakashita S, Nannya Y, Ogawa S, Harada H, Sakata-Yanagimoto M, Nishikii H, Chiba S.

Int J Hematol. 2019 Mar;109(3):309-318. doi: 10.1007/s12185-018-02576-9. Epub 2019 Jan 10.


Antibody engineering to generate SKY59, a long-acting anti-C5 recycling antibody.

Sampei Z, Haraya K, Tachibana T, Fukuzawa T, Shida-Kawazoe M, Gan SW, Shimizu Y, Ruike Y, Feng S, Kuramochi T, Muraoka M, Kitazawa T, Kawabe Y, Igawa T, Hattori K, Nezu J.

PLoS One. 2018 Dec 28;13(12):e0209509. doi: 10.1371/journal.pone.0209509. eCollection 2018.


[Measures taken by public health centers in Kumamoto, Japan, during the hyperacute phase to subacute phase of the Kumamoto earthquake].

Tsurugi Y, Ikeda Y, Inada T, Ogata K, Kiwaki K, Komiya S, Nagano T, Hattori K, Hayashida Y, Fuchigami A.

Nihon Koshu Eisei Zasshi. 2018;65(12):755-768. doi: 10.11236/jph.65.12_755. Japanese. No abstract available.


Transdermal delivery of 40-nm silk fibroin nanoparticles.

Takeuchi I, Shimamura Y, Kakami Y, Kameda T, Hattori K, Miura S, Shirai H, Okumura M, Inagi T, Terada H, Makino K.

Colloids Surf B Biointerfaces. 2019 Mar 1;175:564-568. doi: 10.1016/j.colsurfb.2018.12.012. Epub 2018 Dec 7.


The Imbalance in Medical Demand and Supply for Pediatric Victims in an Earthquake.

Toida C, Takeuchi I, Abe T, Hattori J, Hattori K, Takahashi K, Uchiyama M, Honda H, Nakagawa Y, Matsuda K, Asari Y, Morimura N.

Disaster Med Public Health Prep. 2019 Aug;13(4):672-676. doi: 10.1017/dmp.2018.127. Epub 2018 Dec 21.


Humanization and Simultaneous Optimization of Monoclonal Antibody.

Kuramochi T, Igawa T, Tsunoda H, Hattori K.

Methods Mol Biol. 2019;1904:213-230. doi: 10.1007/978-1-4939-8958-4_9.


Effects of HLD-associated POLR1C mutant proteins on cellular localization and differentiation.

Hiraoka Y, Hattori K, Takeuchi Y, Yamawaki M, Watanabe N, Matsumoto N, Homma K, Miyamoto Y, Yamauchi J.

Mol Genet Metab Rep. 2018 Nov 16;17:80-82. doi: 10.1016/j.ymgmr.2018.11.002. eCollection 2018 Dec. No abstract available.


The fibrinolytic factor tPA drives LRP1-mediated melanoma growth and metastasis.

Salama Y, Lin SY, Dhahri D, Hattori K, Heissig B.

FASEB J. 2019 Mar;33(3):3465-3480. doi: 10.1096/fj.201801339RRR. Epub 2018 Nov 20.


ANGUSTIFOLIA Regulates Actin Filament Alignment for Nuclear Positioning in Leaves.

Iwabuchi K, Ohnishi H, Tamura K, Fukao Y, Furuya T, Hattori K, Tsukaya H, Hara-Nishimura I.

Plant Physiol. 2019 Jan;179(1):233-247. doi: 10.1104/pp.18.01150. Epub 2018 Nov 7.


Genetic evidence implies that primary and relapsed tumors arise from common precursor cells in primary central nervous system lymphoma.

Hattori K, Sakata-Yanagimoto M, Kusakabe M, Nanmoku T, Suehara Y, Matsuoka R, Noguchi M, Yokoyama Y, Kato T, Kurita N, Nishikii H, Obara N, Takano S, Ishikawa E, Matsumura A, Muratani M, Hasegawa Y, Chiba S.

Cancer Sci. 2019 Jan;110(1):401-407. doi: 10.1111/cas.13848. Epub 2018 Nov 18.


Creating a new index to evaluate imbalance in medical demand and supply when disasters occur.

Takahashi K, Morimura N, Takeuchi I, Abe T, Toida C, Hattori J, Hattori K, Honda H, Uchiyama M, Matsuda K, Nakagawa Y, Asari Y.

Acute Med Surg. 2018 Jul 15;5(4):329-336. doi: 10.1002/ams2.353. eCollection 2018 Oct.


Engineering a bispecific antibody with a common light chain: Identification and optimization of an anti-CD3 epsilon and anti-GPC3 bispecific antibody, ERY974.

Shiraiwa H, Narita A, Kamata-Sakurai M, Ishiguro T, Sano Y, Hironiwa N, Tsushima T, Segawa H, Tsunenari T, Ikeda Y, Kayukawa Y, Noguchi M, Wakabayashi T, Sakamoto A, Konishi H, Kuramochi T, Endo M, Hattori K, Nezu J, Igawa T.

Methods. 2019 Feb 1;154:10-20. doi: 10.1016/j.ymeth.2018.10.005. Epub 2018 Oct 13.


In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.

Noshi T, Kitano M, Taniguchi K, Yamamoto A, Omoto S, Baba K, Hashimoto T, Ishida K, Kushima Y, Hattori K, Kawai M, Yoshida R, Kobayashi M, Yoshinaga T, Sato A, Okamatsu M, Sakoda Y, Kida H, Shishido T, Naito A.

Antiviral Res. 2018 Dec;160:109-117. doi: 10.1016/j.antiviral.2018.10.008. Epub 2018 Oct 11.


Association between lower estimated premorbid intelligence quotient and smoking behavior in patients with schizophrenia.

Hidese S, Matsuo J, Ishida I, Hiraishi M, Teraishi T, Ota M, Hattori K, Kunugi H.

Schizophr Res Cogn. 2018 Oct 9;15:7-13. doi: 10.1016/j.scog.2018.09.003. eCollection 2019 Mar.


Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.

Ikeda M, Takahashi A, Kamatani Y, Momozawa Y, Saito T, Kondo K, Shimasaki A, Kawase K, Sakusabe T, Iwayama Y, Toyota T, Wakuda T, Kikuchi M, Kanahara N, Yamamori H, Yasuda Y, Watanabe Y, Hoya S, Aleksic B, Kushima I, Arai H, Takaki M, Hattori K, Kunugi H, Okahisa Y, Ohnuma T, Ozaki N, Someya T, Hashimoto R, Yoshikawa T, Kubo M, Iwata N.

Schizophr Bull. 2019 Jun 18;45(4):824-834. doi: 10.1093/schbul/sby140.


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