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Items: 1 to 50 of 57

1.

Establishment of a glioblastoma in vitro (in)complete resection dual co-culture model suitable for drug testing.

Schmitt C, Adamski V, Rasch F, Adelung R, Lucius R, Synowitz M, Hattermann K, Held-Feindt J.

Ann Anat. 2020 Mar;228:151440. doi: 10.1016/j.aanat.2019.151440. Epub 2019 Nov 11.

2.

APOBEC3B is expressed in human glioma, and influences cell proliferation and temozolomide resistance.

Schmitt C, Lucius R, Synowitz M, Held-Feindt J, Hattermann K.

Oncol Rep. 2018 Nov;40(5):2742-2749. doi: 10.3892/or.2018.6698. Epub 2018 Sep 10.

PMID:
30226610
3.

Effects of sequentially applied single and combined temozolomide, hydroxychloroquine and AT101 treatment in a long-term stimulation glioblastoma in vitro model.

Adamski V, Schmitt C, Ceynowa F, Adelung R, Lucius R, Synowitz M, Hattermann K, Held-Feindt J.

J Cancer Res Clin Oncol. 2018 Aug;144(8):1475-1485. doi: 10.1007/s00432-018-2680-y. Epub 2018 Jun 1.

PMID:
29858681
4.

Modeling treatment-dependent glioma growth including a dormant tumor cell subpopulation.

Böttcher MA, Held-Feindt J, Synowitz M, Lucius R, Traulsen A, Hattermann K.

BMC Cancer. 2018 Apr 3;18(1):376. doi: 10.1186/s12885-018-4281-1.

5.

NKG2D ligands in glioma stem-like cells: expression in situ and in vitro.

Flüh C, Chitadze G, Adamski V, Hattermann K, Synowitz M, Kabelitz D, Held-Feindt J.

Histochem Cell Biol. 2018 Mar;149(3):219-233. doi: 10.1007/s00418-018-1633-5. Epub 2018 Jan 22.

PMID:
29356965
6.

Dormant glioblastoma cells acquire stem cell characteristics and are differentially affected by Temozolomide and AT101 treatment.

Adamski V, Hempelmann A, Flüh C, Lucius R, Synowitz M, Hattermann K, Held-Feindt J.

Oncotarget. 2017 Nov 18;8(64):108064-108078. doi: 10.18632/oncotarget.22514. eCollection 2017 Dec 8.

7.

The Chemokine Receptor CXCR6 Evokes Reverse Signaling via the Transmembrane Chemokine CXCL16.

Adamski V, Mentlein R, Lucius R, Synowitz M, Held-Feindt J, Hattermann K.

Int J Mol Sci. 2017 Jul 8;18(7). pii: E1468. doi: 10.3390/ijms18071468.

8.

Alterations of the Blood-Brain Barrier and Regional Perfusion in Tumor Development: MRI Insights from a Rat C6 Glioma Model.

Huhndorf M, Moussavi A, Kramann N, Will O, Hattermann K, Stadelmann C, Jansen O, Boretius S.

PLoS One. 2016 Dec 22;11(12):e0168174. doi: 10.1371/journal.pone.0168174. eCollection 2016.

9.

"Inverse signaling" of the transmembrane chemokine CXCL16 contributes to proliferative and anti-apoptotic effects in cultured human meningioma cells.

Hattermann K, Bartsch K, Gebhardt HH, Mehdorn HM, Synowitz M, Schmitt AD, Mentlein R, Held-Feindt J.

Cell Commun Signal. 2016 Oct 27;14(1):26.

10.

Stem cell markers in glioma progression and recurrence.

Hattermann K, Flüh C, Engel D, Mehdorn HM, Synowitz M, Mentlein R, Held-Feindt J.

Int J Oncol. 2016 Nov;49(5):1899-1910. doi: 10.3892/ijo.2016.3682. Epub 2016 Sep 6.

PMID:
27600094
11.

Isolation and Characterization of Fast-Migrating Human Glioma Cells in the Progression of Malignant Gliomas.

Adamski V, Schmitt AD, Flüh C, Synowitz M, Hattermann K, Held-Feindt J.

Oncol Res. 2017 Mar 13;25(3):341-353. doi: 10.3727/096504016X14737243054982. Epub 2016 Sep 16.

PMID:
27641619
12.

Differential expression of CXCR4 and CXCR7 with various stem cell markers in paired human primary and recurrent glioblastomas.

Flüh C, Hattermann K, Mehdorn HM, Synowitz M, Held-Feindt J.

Int J Oncol. 2016 Apr;48(4):1408-16. doi: 10.3892/ijo.2016.3354. Epub 2016 Jan 25.

PMID:
26821357
13.

Transmembrane chemokines act as receptors in a novel mechanism termed inverse signaling.

Hattermann K, Gebhardt H, Krossa S, Ludwig A, Lucius R, Held-Feindt J, Mentlein R.

Elife. 2016 Jan 21;5:e10820. doi: 10.7554/eLife.10820.

14.

CXCR4 and CXCR7 Mediate TFF3-Induced Cell Migration Independently From the ERK1/2 Signaling Pathway.

Dieckow J, Brandt W, Hattermann K, Schob S, Schulze U, Mentlein R, Ackermann P, Sel S, Paulsen FP.

Invest Ophthalmol Vis Sci. 2016 Jan 1;57(1):56-65. doi: 10.1167/iovs.15-18129.

PMID:
26780310
15.

The role of Fc-receptors in the uptake and transport of therapeutic antibodies in the retinal pigment epithelium.

Dithmer M, Hattermann K, Pomarius P, Aboul Naga SH, Meyer T, Mentlein R, Roider J, Klettner A.

Exp Eye Res. 2016 Apr;145:187-205. doi: 10.1016/j.exer.2015.12.013. Epub 2016 Jan 8.

PMID:
26773870
16.

Erythropoietin and CCL3 antagonise their functional properties during neuroinflammation.

Hattermann K, Knerlich-Lukoschus F, Lucius R, Mehdorn M, Held-Feindt J.

Neurol Res. 2015 Nov;37(11):1025-8. doi: 10.1179/1743132815Y.0000000070. Epub 2015 Jul 16.

PMID:
26178913
17.

Down regulation of Akirin-2 increases chemosensitivity in human glioblastomas more efficiently than Twist-1.

Krossa S, Schmitt AD, Hattermann K, Fritsch J, Scheidig AJ, Mehdorn HM, Held-Feindt J.

Oncotarget. 2015 Aug 28;6(25):21029-45.

18.

Epithelial-to-mesenchymal transition in paired human primary and recurrent glioblastomas.

Kubelt C, Hattermann K, Sebens S, Mehdorn HM, Held-Feindt J.

Int J Oncol. 2015;46(6):2515-25. doi: 10.3892/ijo.2015.2944. Epub 2015 Mar 31.

PMID:
25845427
19.

Expression of DNA mismatch repair proteins MLH1, MSH2, and MSH6 in recurrent glioblastoma.

Stark AM, Doukas A, Hugo HH, Hedderich J, Hattermann K, Maximilian Mehdorn H, Held-Feindt J.

Neurol Res. 2015 Feb;37(2):95-105. doi: 10.1179/1743132814Y.0000000409. Epub 2014 Jul 4.

PMID:
24995467
20.

Chemokine expression profile of freshly isolated human glioblastoma-associated macrophages/microglia.

Hattermann K, Sebens S, Helm O, Schmitt AD, Mentlein R, Mehdorn HM, Held-Feindt J.

Oncol Rep. 2014 Jul;32(1):270-6. doi: 10.3892/or.2014.3214. Epub 2014 May 23.

PMID:
24859792
21.

Effects of the chemokine CXCL12 and combined internalization of its receptors CXCR4 and CXCR7 in human MCF-7 breast cancer cells.

Hattermann K, Holzenburg E, Hans F, Lucius R, Held-Feindt J, Mentlein R.

Cell Tissue Res. 2014 Jul;357(1):253-66. doi: 10.1007/s00441-014-1823-y. Epub 2014 Apr 26.

22.

Expression of the chemokines CXCL12 and CX3CL1 and their receptors in human nerve sheath tumors.

Hattermann K, Li G, Hugo HH, Mentlein R, Mehdorn HM, Held-Feindt J.

Histol Histopathol. 2013 Oct;28(10):1337-49. doi: 10.14670/HH-28.1337. Epub 2013 May 6.

PMID:
23645563
23.

The CXCL16-CXCR6 chemokine axis in glial tumors.

Hattermann K, Held-Feindt J, Ludwig A, Mentlein R.

J Neuroimmunol. 2013 Jul 15;260(1-2):47-54. doi: 10.1016/j.jneuroim.2013.04.006. Epub 2013 Apr 28.

PMID:
23628207
24.

An infernal trio: the chemokine CXCL12 and its receptors CXCR4 and CXCR7 in tumor biology.

Hattermann K, Mentlein R.

Ann Anat. 2013 Mar;195(2):103-10. doi: 10.1016/j.aanat.2012.10.013. Epub 2012 Dec 8. Review.

PMID:
23279723
25.

The transmembrane chemokines CXCL16 and CX3CL1 and their receptors are expressed in human meningiomas.

Li G, Hattermann K, Mentlein R, Mehdorn HM, Held-Feindt J.

Oncol Rep. 2013 Feb;29(2):563-70. doi: 10.3892/or.2012.2164. Epub 2012 Dec 3.

PMID:
23229614
26.

The transcription factor Forkhead box P3 (FoxP3) is expressed in glioma cells and associated with increased apoptosis.

Held-Feindt J, Hattermann K, Sebens S, Krautwald S, Mehdorn HM, Mentlein R.

Exp Cell Res. 2013 Mar 10;319(5):731-9. doi: 10.1016/j.yexcr.2012.11.018. Epub 2012 Dec 1.

PMID:
23211717
27.

The neural adhesion molecule L1CAM confers chemoresistance in human glioblastomas.

Held-Feindt J, Schmelz S, Hattermann K, Mentlein R, Mehdorn HM, Sebens S.

Neurochem Int. 2012 Dec;61(7):1183-91. doi: 10.1016/j.neuint.2012.08.011. Epub 2012 Aug 28.

PMID:
22948185
28.

CXCL12 mediates apoptosis resistance in rat C6 glioma cells.

Hattermann K, Mentlein R, Held-Feindt J.

Oncol Rep. 2012 May;27(5):1348-52. doi: 10.3892/or.2012.1674. Epub 2012 Feb 6.

PMID:
22323084
29.

Lost in disruption: role of proteases in glioma invasion and progression.

Mentlein R, Hattermann K, Held-Feindt J.

Biochim Biophys Acta. 2012 Apr;1825(2):178-85. doi: 10.1016/j.bbcan.2011.12.001. Epub 2011 Dec 22. Review.

PMID:
22209868
30.

The presumed atypical chemokine receptor CXCR7 signals through G(i/o) proteins in primary rodent astrocytes and human glioma cells.

Odemis V, Lipfert J, Kraft R, Hajek P, Abraham G, Hattermann K, Mentlein R, Engele J.

Glia. 2012 Mar;60(3):372-81. doi: 10.1002/glia.22271. Epub 2011 Nov 14.

PMID:
22083878
31.

Near-infrared molecular imaging of tumors via chemokine receptors CXCR4 and CXCR7.

Meincke M, Tiwari S, Hattermann K, Kalthoff H, Mentlein R.

Clin Exp Metastasis. 2011 Dec;28(8):713-20. doi: 10.1007/s10585-011-9403-y. Epub 2011 Jul 7.

32.

Spheroid confrontation assay: a simple method to monitor the three-dimensional migration of different cell types in vitro.

Hattermann K, Held-Feindt J, Mentlein R.

Ann Anat. 2011 May;193(3):181-4. doi: 10.1016/j.aanat.2010.12.005. Epub 2011 Feb 3.

PMID:
21339059
33.

SP100 reduces malignancy of human glioma cells.

Held-Feindt J, Hattermann K, Knerlich-Lukoschus F, Mehdorn HM, Mentlein R.

Int J Oncol. 2011 Apr;38(4):1023-30. doi: 10.3892/ijo.2011.927. Epub 2011 Jan 27.

PMID:
21274506
34.

Expression and role of the cell surface protease seprase/fibroblast activation protein-α (FAP-α) in astroglial tumors.

Mentlein R, Hattermann K, Hemion C, Jungbluth AA, Held-Feindt J.

Biol Chem. 2011 Mar;392(3):199-207. doi: 10.1515/BC.2010.119.

PMID:
20707604
35.

The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects.

Hattermann K, Held-Feindt J, Lucius R, Müerköster SS, Penfold ME, Schall TJ, Mentlein R.

Cancer Res. 2010 Apr 15;70(8):3299-308. doi: 10.1158/0008-5472.CAN-09-3642. Epub 2010 Apr 13.

36.

CX3CR1 promotes recruitment of human glioma-infiltrating microglia/macrophages (GIMs).

Held-Feindt J, Hattermann K, Müerköster SS, Wedderkopp H, Knerlich-Lukoschus F, Ungefroren H, Mehdorn HM, Mentlein R.

Exp Cell Res. 2010 May 15;316(9):1553-66. doi: 10.1016/j.yexcr.2010.02.018. Epub 2010 Feb 23.

PMID:
20184883
37.

Matrix metalloproteinase-19 is highly expressed in astroglial tumors and promotes invasion of glioma cells.

Lettau I, Hattermann K, Held-Feindt J, Brauer R, Sedlacek R, Mentlein R.

J Neuropathol Exp Neurol. 2010 Mar;69(3):215-23. doi: 10.1097/NEN.0b013e3181ce9f67.

PMID:
20142769
38.

VEGFR-3/Flt-4 mediates proliferation and chemotaxis in glial precursor cells.

Kranich S, Hattermann K, Specht A, Lucius R, Mentlein R.

Neurochem Int. 2009 Dec;55(8):747-53. doi: 10.1016/j.neuint.2009.07.007. Epub 2009 Jul 29.

PMID:
19646499
39.

The chemokine CXCL16 induces migration and invasion of glial precursor cells via its receptor CXCR6.

Hattermann K, Ludwig A, Gieselmann V, Held-Feindt J, Mentlein R.

Mol Cell Neurosci. 2008 Sep;39(1):133-41. doi: 10.1016/j.mcn.2008.03.009. Epub 2008 Apr 10.

PMID:
18619850
40.

A functional toll-like receptor 8 variant is associated with HIV disease restriction.

Oh DY, Taube S, Hamouda O, Kücherer C, Poggensee G, Jessen H, Eckert JK, Neumann K, Storek A, Pouliot M, Borgeat P, Oh N, Schreier E, Pruss A, Hattermann K, Schumann RR.

J Infect Dis. 2008 Sep 1;198(5):701-9. doi: 10.1086/590431.

PMID:
18605904
41.

A methylation-specific and SYBR-green-based quantitative polymerase chain reaction technique for O6-methylguanine DNA methyltransferase promoter methylation analysis.

Hattermann K, Mehdorn HM, Mentlein R, Schultka S, Held-Feindt J.

Anal Biochem. 2008 Jun 1;377(1):62-71. doi: 10.1016/j.ab.2008.03.014. Epub 2008 Mar 14.

PMID:
18384736
42.

Overexpression of CXCL16 and its receptor CXCR6/Bonzo promotes growth of human schwannomas.

Held-Feindt J, Rehmke B, Mentlein R, Hattermann K, Knerlich F, Hugo HH, Ludwig A, Mehdorn HM.

Glia. 2008 May;56(7):764-74. doi: 10.1002/glia.20651.

PMID:
18293410
43.

Endoglin expression in metastatic breast cancer cells enhances their invasive phenotype.

Oxmann D, Held-Feindt J, Stark AM, Hattermann K, Yoneda T, Mentlein R.

Oncogene. 2008 Jun 5;27(25):3567-75. doi: 10.1038/sj.onc.1211025. Epub 2008 Jan 28.

PMID:
18223685
44.

Interleukin 27 induces differentiation of neural C6-precursor cells into astrocytes.

Koch M, May U, Kuhns S, Drechsler H, Adam N, Hattermann K, Wirtz S, Rose-John S, Scheller J.

Biochem Biophys Res Commun. 2007 Dec 21;364(3):483-7. Epub 2007 Oct 17.

PMID:
17961512
45.

Investigations on the aetiology of pinching off syndrome in four white-tailed sea eagles (Haliaeetus albicilla) from Germany.

Müller K, Schettler E, Gerlach H, Brunnberg L, Hafez HM, Hattermann K, Johne R, Kollmann R, Krone O, Lierz M, Linke S, Lueschow D, Mankertz A, Müller H, Prusas C, Raue R, Soike D, Speck S, Wolf P, Frölich K.

Avian Pathol. 2007 Jun;36(3):235-43.

PMID:
17497338
46.

The Toll-like receptor 7/8-ligand resiquimod (R-848) primes human neutrophils for leukotriene B4, prostaglandin E2 and platelet-activating factor biosynthesis.

Hattermann K, Picard S, Borgeat M, Leclerc P, Pouliot M, Borgeat P.

FASEB J. 2007 May;21(7):1575-85. Epub 2007 Jan 30.

PMID:
17264163
47.

Susceptibility of different eukaryotic cell lines to SARS-coronavirus.

Hattermann K, Müller MA, Nitsche A, Wendt S, Donoso Mantke O, Niedrig M.

Arch Virol. 2005 May;150(5):1023-31. Epub 2005 Jan 13.

48.

Assessing the risk potential of porcine circoviruses for xenotransplantation: consensus primer-PCR-based search for a human circovirus.

Hattermann K, Maerz A, Slanina H, Schmitt C, Mankertz A.

Xenotransplantation. 2004 Nov;11(6):547-50.

PMID:
15479465
49.

Novel circovirus in mulard ducks with developmental and feathering disorders.

Soike D, Albrecht K, Hattermann K, Schmitt C, Mankertz A.

Vet Rec. 2004 Jun 19;154(25):792-3. No abstract available.

PMID:
15233459
50.

S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected patients.

Hofmann H, Hattermann K, Marzi A, Gramberg T, Geier M, Krumbiegel M, Kuate S, Uberla K, Niedrig M, Pöhlmann S.

J Virol. 2004 Jun;78(12):6134-42.

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