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Items: 14


The Expansion of Heterotopic Bone in Fibrodysplasia Ossificans Progressiva Is Activin A-Dependent.

Upadhyay J, Xie L, Huang L, Das N, Stewart RC, Lyon MC, Palmer K, Rajamani S, Graul C, Lobo M, Wellman TJ, Soares EJ, Silva MD, Hesterman J, Wang L, Wen X, Qian X, Nannuru K, Idone V, Murphy AJ, Economides AN, Hatsell SJ.

J Bone Miner Res. 2017 Dec;32(12):2489-2499. doi: 10.1002/jbmr.3235. Epub 2017 Sep 22.


The obligatory role of Activin A in the formation of heterotopic bone in Fibrodysplasia Ossificans Progressiva.

Alessi Wolken DM, Idone V, Hatsell SJ, Yu PB, Economides AN.

Bone. 2018 Apr;109:210-217. doi: 10.1016/j.bone.2017.06.011. Epub 2017 Jun 16. Review.


Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification.

Dey D, Bagarova J, Hatsell SJ, Armstrong KA, Huang L, Ermann J, Vonner AJ, Shen Y, Mohedas AH, Lee A, Eekhoff EM, van Schie A, Demay MB, Keller C, Wagers AJ, Economides AN, Yu PB.

Sci Transl Med. 2016 Nov 23;8(366):366ra163.


ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A.

Hatsell SJ, Idone V, Wolken DM, Huang L, Kim HJ, Wang L, Wen X, Nannuru KC, Jimenez J, Xie L, Das N, Makhoul G, Chernomorsky R, D'Ambrosio D, Corpina RA, Schoenherr CJ, Feeley K, Yu PB, Yancopoulos GD, Murphy AJ, Economides AN.

Sci Transl Med. 2015 Sep 2;7(303):303ra137. doi: 10.1126/scitranslmed.aac4358.


Gli activity is critical at multiple stages of embryonic mammary and nipple development.

Chandramouli A, Hatsell SJ, Pinderhughes A, Koetz L, Cowin P.

PLoS One. 2013 Nov 18;8(11):e79845. doi: 10.1371/journal.pone.0079845. eCollection 2013.


Conditionals by inversion provide a universal method for the generation of conditional alleles.

Economides AN, Frendewey D, Yang P, Dominguez MG, Dore AT, Lobov IB, Persaud T, Rojas J, McClain J, Lengyel P, Droguett G, Chernomorsky R, Stevens S, Auerbach W, Dechiara TM, Pouyemirou W, Cruz JM Jr, Feeley K, Mellis IA, Yasenchack J, Hatsell SJ, Xie L, Latres E, Huang L, Zhang Y, Pefanis E, Skokos D, Deckelbaum RA, Croll SD, Davis S, Valenzuela DM, Gale NW, Murphy AJ, Yancopoulos GD.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3179-88. doi: 10.1073/pnas.1217812110. Epub 2013 Aug 5.


MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors.

Teissedre B, Pinderhughes A, Incassati A, Hatsell SJ, Hiremath M, Cowin P.

PLoS One. 2009;4(2):e4537. doi: 10.1371/journal.pone.0004537. Epub 2009 Feb 19. Erratum in: PLoS ONE. 2009;4(3). doi: 10.1371/annotation/3706d475-e082-4be6-b328-7d8aea02b986.


Gli3-mediated repression of Hedgehog targets is required for normal mammary development.

Hatsell SJ, Cowin P.

Development. 2006 Sep;133(18):3661-70. Epub 2006 Aug 16.


Cadherins and catenins in breast cancer.

Cowin P, Rowlands TM, Hatsell SJ.

Curr Opin Cell Biol. 2005 Oct;17(5):499-508. Review.


Dissecting the roles of beta-catenin and cyclin D1 during mammary development and neoplasia.

Rowlands TM, Pechenkina IV, Hatsell SJ, Pestell RG, Cowin P.

Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11400-5. Epub 2003 Sep 17.


An autosomal recessive exfoliative ichthyosis with linkage to chromosome 12q13.

Hatsell SJ, Stevens H, Jackson AP, Kelsell DP, Zvulunov A.

Br J Dermatol. 2003 Jul;149(1):174-80.


Whats new in genodermatoses?

Fear MW, Hatsell SJ, Leigh IM, Kelsell DP.

Keio J Med. 2001 Mar;50(1):35-8.


Novel splice site mutation in keratin 1 underlies mild epidermolytic palmoplantar keratoderma in three kindreds.

Hatsell SJ, Eady RA, Wennerstrand L, Dopping-Hepenstal P, Leigh IM, Munro C, Kelsell DP.

J Invest Dermatol. 2001 Apr;116(4):606-9.


Recessive mutation in desmoplakin disrupts desmoplakin-intermediate filament interactions and causes dilated cardiomyopathy, woolly hair and keratoderma.

Norgett EE, Hatsell SJ, Carvajal-Huerta L, Cabezas JC, Common J, Purkis PE, Whittock N, Leigh IM, Stevens HP, Kelsell DP.

Hum Mol Genet. 2000 Nov 1;9(18):2761-6.


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