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Items: 1 to 50 of 65

1.

ATM deficiency promotes development of murine B-cell lymphomas that resemble diffuse large B-cell lymphoma in humans.

Hathcock KS, Padilla-Nash HM, Camps J, Shin DM, Triner D, Shaffer AL 3rd, Maul RW, Steinberg SM, Gearhart PJ, Staudt LM, Morse HC 3rd, Ried T, Hodes RJ.

Blood. 2015 Nov 12;126(20):2291-301. doi: 10.1182/blood-2015-06-654749. Epub 2015 Sep 23.

2.

Downmodulation of tumor suppressor p53 by T cell receptor signaling is critical for antigen-specific CD4(+) T cell responses.

Watanabe M, Moon KD, Vacchio MS, Hathcock KS, Hodes RJ.

Immunity. 2014 May 15;40(5):681-91. doi: 10.1016/j.immuni.2014.04.006. Epub 2014 May 1.

3.

ATM influences the efficiency of TCRβ rearrangement, subsequent TCRβ-dependent T cell development, and generation of the pre-selection TCRβ CDR3 repertoire.

Hathcock KS, Bowen S, Livak F, Hodes RJ.

PLoS One. 2013 Apr 23;8(4):e62188. doi: 10.1371/journal.pone.0062188. Print 2013.

4.

The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement.

Hathcock KS, Farrington L, Ivanova I, Livak F, Selimyan R, Sen R, Williams J, Tai X, Hodes RJ.

PLoS One. 2011;6(6):e20639. doi: 10.1371/journal.pone.0020639. Epub 2011 Jun 3.

5.

Telomere length is inherited with resetting of the telomere set-point.

Chiang YJ, Calado RT, Hathcock KS, Lansdorp PM, Young NS, Hodes RJ.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10148-53. doi: 10.1073/pnas.0913125107. Epub 2010 May 17.

6.

Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence.

Nakamura AJ, Chiang YJ, Hathcock KS, Horikawa I, Sedelnikova OA, Hodes RJ, Bonner WM.

Epigenetics Chromatin. 2008 Nov 3;1(1):6. doi: 10.1186/1756-8935-1-6.

7.

Analysis of telomere length and telomerase activity.

Hathcock KS, Hodes RJ, Weng NP.

Curr Protoc Immunol. 2004 Sep;Chapter 10:Unit 10.30. doi: 10.1002/0471142735.im1030s62. Review.

PMID:
18432920
8.

Depletion of accessory cells by adherence to Sephadex G-10.

Hathcock KS.

Curr Protoc Immunol. 2001 May;Chapter 3:Unit 3.6. doi: 10.1002/0471142735.im0306s08.

PMID:
18432790
9.

T cell depletion by cytotoxic elimination.

Hathcock KS.

Curr Protoc Immunol. 2001 May;Chapter 3:Unit 3.4. doi: 10.1002/0471142735.im0304s00.

PMID:
18432789
10.

T cell enrichment by nonadherence to nylon.

Hathcock KS.

Curr Protoc Immunol. 2001 May;Chapter 3:Unit 3.2. doi: 10.1002/0471142735.im0302s30.

PMID:
18432784
11.

Persistence of tumor infiltrating lymphocytes in adoptive immunotherapy correlates with telomere length.

Shen X, Zhou J, Hathcock KS, Robbins P, Powell DJ Jr, Rosenberg SA, Hodes RJ.

J Immunother. 2007 Jan;30(1):123-9.

12.

Abnormal differentiation of memory T cells in systemic lupus erythematosus.

Fritsch RD, Shen X, Illei GG, Yarboro CH, Prussin C, Hathcock KS, Hodes RJ, Lipsky PE.

Arthritis Rheum. 2006 Jul;54(7):2184-97.

13.

Stepwise differentiation of CD4 memory T cells defined by expression of CCR7 and CD27.

Fritsch RD, Shen X, Sims GP, Hathcock KS, Hodes RJ, Lipsky PE.

J Immunol. 2005 Nov 15;175(10):6489-97.

14.

Regulated costimulation in the thymus is critical for T cell development: dysregulated CD28 costimulation can bypass the pre-TCR checkpoint.

Williams JA, Hathcock KS, Klug D, Harada Y, Choudhury B, Allison JP, Abe R, Hodes RJ.

J Immunol. 2005 Oct 1;175(7):4199-207.

15.

Telomere biology and immune system.

Hathcock KS, Chiang YJ, Hodes RJ.

Discov Med. 2005 Jun;5(27):288-92.

16.

In vivo regulation of telomerase activity and telomere length.

Hathcock KS, Jeffrey Chiang Y, Hodes RJ.

Immunol Rev. 2005 Jun;205:104-13. Review.

PMID:
15882348
17.

Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo.

Chiang YJ, Hemann MT, Hathcock KS, Tessarollo L, Feigenbaum L, Hahn WC, Hodes RJ.

Mol Cell Biol. 2004 Aug;24(16):7024-31.

18.
19.

Telomeres in T and B cells.

Hodes RJ, Hathcock KS, Weng NP.

Nat Rev Immunol. 2002 Sep;2(9):699-706. Review.

PMID:
12209138
20.

Haploinsufficiency of mTR results in defects in telomere elongation.

Hathcock KS, Hemann MT, Opperman KK, Strong MA, Greider CW, Hodes RJ.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3591-6.

21.
22.

Regulation of telomere length and telomerase in T and B cells: a mechanism for maintaining replicative potential.

Weng NP, Hathcock KS, Hodes RJ.

Immunity. 1998 Aug;9(2):151-7. Review. No abstract available.

23.

Telomere length regulation in mice is linked to a novel chromosome locus.

Zhu L, Hathcock KS, Hande P, Lansdorp PM, Seldin MF, Hodes RJ.

Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8648-53.

24.

Cutting edge: antigen-dependent regulation of telomerase activity in murine T cells.

Hathcock KS, Weng NP, Merica R, Jenkins MK, Hodes R.

J Immunol. 1998 Jun 15;160(12):5702-6.

25.

Role of the CD28-B7 costimulatory pathways in T cell-dependent B cell responses.

Hathcock KS, Hodes RJ.

Adv Immunol. 1996;62:131-66. Review. No abstract available.

PMID:
8781268
26.

Inhibition of transplant rejection following treatment with anti-B7-2 and anti-B7-1 antibodies.

Lenschow DJ, Zeng Y, Hathcock KS, Zuckerman LA, Freeman G, Thistlethwaite JR, Gray GS, Hodes RJ, Bluestone JA.

Transplantation. 1995 Nov 27;60(10):1171-8.

PMID:
7482727
27.

Analysis of thymic subpopulations expressing the activation antigen GL7. Expression, genetics, and function.

Hathcock KS, Pucillo CE, Laszlo G, Lai L, Hodes RJ.

J Immunol. 1995 Nov 15;155(10):4575-81.

PMID:
7594455
28.

The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro.

Inaba K, Witmer-Pack M, Inaba M, Hathcock KS, Sakuta H, Azuma M, Yagita H, Okumura K, Linsley PS, Ikehara S, Muramatsu S, Hodes RJ, Steinman RM.

J Exp Med. 1994 Nov 1;180(5):1849-60.

29.

Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function.

Hathcock KS, Laszlo G, Pucillo C, Linsley P, Hodes RJ.

J Exp Med. 1994 Aug 1;180(2):631-40.

30.

Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.

Larsen CP, Ritchie SC, Hendrix R, Linsley PS, Hathcock KS, Hodes RJ, Lowry RP, Pearson TC.

J Immunol. 1994 Jun 1;152(11):5208-19.

PMID:
7514631
31.

CD44 expression on activated B cells. Differential capacity for CD44-dependent binding to hyaluronic acid.

Hathcock KS, Hirano H, Murakami S, Hodes RJ.

J Immunol. 1993 Dec 15;151(12):6712-22.

PMID:
7505013
32.

Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice.

Freeman GJ, Borriello F, Hodes RJ, Reiser H, Hathcock KS, Laszlo G, McKnight AJ, Kim J, Du L, Lombard DB, et al.

Science. 1993 Nov 5;262(5135):907-9.

PMID:
7694362
33.

Identification of an alternative CTLA-4 ligand costimulatory for T cell activation.

Hathcock KS, Laszlo G, Dickler HB, Bradshaw J, Linsley P, Hodes RJ.

Science. 1993 Nov 5;262(5135):905-7.

PMID:
7694361
34.

Characterization of a novel cell-surface molecule expressed on subpopulations of activated T and B cells.

Laszlo G, Hathcock KS, Dickler HB, Hodes RJ.

J Immunol. 1993 Jun 15;150(12):5252-62.

PMID:
8515058
35.
36.

CD45 expression by B cells. Expression of different CD45 isoforms by subpopulations of activated B cells.

Hathcock KS, Hirano H, Murakami S, Hodes RJ.

J Immunol. 1992 Oct 1;149(7):2286-94.

PMID:
1388188
37.

Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations.

Hathcock KS, Laszlo G, Dickler HB, Sharrow SO, Johnson P, Trowbridge IS, Hodes RJ.

J Immunol. 1992 Jan 1;148(1):19-28.

PMID:
1370168
38.

Antigen-specific helper function of cell-free T cell products bearing TCR V beta 8 determinants.

Guy R, Ullrich SJ, Foo-Philips M, Hathcock KS, Appella E, Hodes RJ.

Science. 1989 Jun 23;244(4911):1477-80.

PMID:
2472009
39.

Activation of Lyt-2+ (CD8+) and L3T4+ (CD4+) T cell subsets by anti-receptor antibody.

Hathcock KS, Segal DM, Hodes RJ.

J Immunol. 1989 Apr 1;142(7):2181-6.

PMID:
2784455
40.

Influence of helper T cells on the expression of a murine intrastrain crossreactive idiotype.

Hathcock KS, Gurish MF, Nisonoff A, Conger JD, Hodes RJ.

Proc Natl Acad Sci U S A. 1986 Jan;83(1):155-9.

41.

Helper T cell requirements for T15 idiotype expression on phosphorylcholine-specific antibodies.

Hathcock KS, Kenny JJ, Hodes RJ.

Eur J Immunol. 1985 Jun;15(6):564-9.

PMID:
3159584
45.

Major histocompatibility complex-restricted recognition by B lymphocytes and accessory cells.

Hodes RJ, Hathcock KS, Singer A.

Surv Immunol Res. 1983;2(3):220-2. No abstract available.

PMID:
6232670
48.

Major histocompatibility complex restricted self-recognition by B cells and T cells in responses to TNP-Ficoll.

Hodes RJ, Hathcock KS, Singer A.

Immunol Rev. 1982;69:25-50. No abstract available.

PMID:
6984000
49.

Distinct B cell subpopulations differ in their genetic requirements for activation by T helper cells.

Singer A, Asano Y, Shigeta M, Hathcock KS, Ahmed A, Fathman CG, Hodes RJ.

Immunol Rev. 1982;64:137-60. Review. No abstract available.

PMID:
6806171

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