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Predictors and outcomes of stroke after transcatheter aortic valve replacement.

Hatfield SA, Nores MA, James TM, Rothenberg M, Kapila A, Cubeddu RJ, Stamou SC.

J Card Surg. 2020 Jan;35(1):21-27. doi: 10.1111/jocs.14300. Epub 2019 Dec 3.


Mechanistic Justifications of Systemic Therapeutic Oxygenation of Tumors to Weaken the Hypoxia Inducible Factor 1α-Mediated Immunosuppression.

Hatfield S, Veszeleiova K, Steingold J, Sethuraman J, Sitkovsky M.

Adv Exp Med Biol. 2019;1136:113-121. doi: 10.1007/978-3-030-12734-3_8. Review.


Corrigendum: Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells.

Sorrentino C, Hossain F, Rodriguez PC, Sierra RA, Pannuti A, Hatfield S, Osborne BA, Minter LM, Miele L, Morello S.

Front Immunol. 2019 May 3;10:935. doi: 10.3389/fimmu.2019.00935. eCollection 2019.


Modulation of inflammation in wounds of diabetic patients treated with porcine urinary bladder matrix.

Paige JT, Kremer M, Landry J, Hatfield SA, Wathieu D, Brug A, Lightell DJ, Spiller KL, Woods TC.

Regen Med. 2019 May;14(4):269-277. doi: 10.2217/rme-2019-0009. Epub 2019 Apr 25.


A2A Adenosine Receptor Gene Deletion or Synthetic A2A Antagonist Liberate Tumor-Reactive CD8+ T Cells from Tumor-Induced Immunosuppression.

Kjaergaard J, Hatfield S, Jones G, Ohta A, Sitkovsky M.

J Immunol. 2018 Jul 15;201(2):782-791. doi: 10.4049/jimmunol.1700850. Epub 2018 May 25.


Weak vaccinia virus-induced NK cell regulation of CD4 T cells is associated with reduced NK cell differentiation and cytolytic activity.

Hatfield SD, Daniels KA, O'Donnell CL, Waggoner SN, Welsh RM.

Virology. 2018 Jun;519:131-144. doi: 10.1016/j.virol.2018.04.012. Epub 2018 Apr 30.


Targeted Elimination of Immunodominant B Cells Drives the Germinal Center Reaction toward Subdominant Epitopes.

Silva M, Nguyen TH, Philbrook P, Chu M, Sears O, Hatfield S, Abbott RK, Kelsoe G, Sitkovsky MV.

Cell Rep. 2017 Dec 26;21(13):3672-3680. doi: 10.1016/j.celrep.2017.12.014.


Fluorinated Adenosine A2A Receptor Antagonists Inspired by Preladenant as Potential Cancer Immunotherapeutics.

Yuan G, Jankins TC, Patrick CG Jr, Philbrook P, Sears O, Hatfield S, Sitkovsky M, Vasdev N, Liang SH, Ondrechen MJ, Pollastri MP, Jones GB.

Int J Med Chem. 2017;2017:4852537. doi: 10.1155/2017/4852537. Epub 2017 Oct 19.


Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells.

Sethumadhavan S, Silva M, Philbrook P, Nguyen T, Hatfield SM, Ohta A, Sitkovsky MV.

PLoS One. 2017 Nov 20;12(11):e0187314. doi: 10.1371/journal.pone.0187314. eCollection 2017.


Carotid Plaque Rupture Is Accompanied by an Increase in the Ratio of Serum circR-284 to miR-221 Levels.

Bazan HA, Hatfield SA, Brug A, Brooks AJ, Lightell DJ Jr, Woods TC.

Circ Cardiovasc Genet. 2017 Aug;10(4). pii: e001720. doi: 10.1161/CIRCGENETICS.117.001720.


Patient Perceptions on Facilitating Follow-Up After Heart Failure Hospitalization.

Breathett K, D'Amico R, Adesanya TMA, Hatfield S, Willis S, Sturdivant RX, Foraker RE, Smith S, Binkley P, Abraham WT, Peterson PN.

Circ Heart Fail. 2017 Jun;10(6). pii: e004099. doi: 10.1161/CIRCHEARTFAILURE.117.004099.


Evaluating the effects of organizational and educational interventions on adherence to clinical practice guidelines in a low-resource primary-care setting in Kenya.

Egger JR, Stankevitz K, Korom R, Angwenyi P, Sullivan B, Wang J, Hatfield S, Smith E, Popli K, Gross J.

Health Policy Plan. 2017 Jul 1;32(6):761-768. doi: 10.1093/heapol/czx004.


Angular Relationship Between the Foramen Ovale and the Trigeminal Impression: Percutaneous Cannulation Trajectories for Trigeminal Neuralgia.

Zdilla MJ, Hatfield SA, Mangus KR.

J Craniofac Surg. 2016 Nov;27(8):2177-2180. doi: 10.1097/SCS.0000000000003138.


The GS Protein-coupled A2a Adenosine Receptor Controls T Cell Help in the Germinal Center.

Abbott RK, Silva M, Labuda J, Thayer M, Cain DW, Philbrook P, Sethumadhavan S, Hatfield S, Ohta A, Sitkovsky M.

J Biol Chem. 2017 Jan 27;292(4):1211-1217. doi: 10.1074/jbc.C116.764043. Epub 2016 Dec 14.


What's new in atopic eczema? An analysis of systematic reviews published in 2014. Part 2. Treatment and prevention.

Lloyd-Lavery A, Rogers NK, Hatfield SJ, Grindlay D, Barnett R, Thomas KS.

Clin Exp Dermatol. 2017 Jan;42(1):3-7. doi: 10.1111/ced.12967. Epub 2016 Nov 21. Review.


What's new in atopic eczema? An analysis of systematic reviews published in 2014. Part 1. Epidemiology, risk factors and outcomes.

Hatfield SJ, Rogers NK, Lloyd-Lavery A, Grindlay D, Barnett R, Thomas KS.

Clin Exp Dermatol. 2016 Dec;41(8):843-846. doi: 10.1111/ced.12977. Epub 2016 Nov 2. Review.


Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination.

Abbott RK, Thayer M, Labuda J, Silva M, Philbrook P, Cain DW, Kojima H, Hatfield S, Sethumadhavan S, Ohta A, Reinherz EL, Kelsoe G, Sitkovsky M.

J Immunol. 2016 Nov 15;197(10):4014-4020. Epub 2016 Oct 19.


A2A adenosine receptor antagonists to weaken the hypoxia-HIF-1α driven immunosuppression and improve immunotherapies of cancer.

Hatfield SM, Sitkovsky M.

Curr Opin Pharmacol. 2016 Aug;29:90-6. doi: 10.1016/j.coph.2016.06.009. Epub 2016 Jul 17. Review.


Orientation of the Foramen Ovale: An Anatomic Study With Neurosurgical Considerations.

Zdilla MJ, Hatfield SA, McLean KA, Laslo JM, Cyrus LM, Lambert HW.

J Craniofac Surg. 2016 Jan;27(1):234-7. doi: 10.1097/SCS.0000000000002332.


Circularity, Solidity, Axes of a Best Fit Ellipse, Aspect Ratio, and Roundness of the Foramen Ovale: A Morphometric Analysis With Neurosurgical Considerations.

Zdilla MJ, Hatfield SA, McLean KA, Cyrus LM, Laslo JM, Lambert HW.

J Craniofac Surg. 2016 Jan;27(1):222-8. doi: 10.1097/SCS.0000000000002285.


Oxygenation to improve cancer vaccines, adoptive cell transfer and blockade of immunological negative regulators.

Hatfield SM, Sitkovsky M.

Oncoimmunology. 2015 Jun 1;4(12):e1052934. eCollection 2015 Dec.


Acute Loss of miR-221 and miR-222 in the Atherosclerotic Plaque Shoulder Accompanies Plaque Rupture.

Bazan HA, Hatfield SA, O'Malley CB, Brooks AJ, Lightell D Jr, Woods TC.

Stroke. 2015 Nov;46(11):3285-7. doi: 10.1161/STROKEAHA.115.010567. Epub 2015 Oct 8.


Immunological mechanisms of the antitumor effects of supplemental oxygenation.

Hatfield SM, Kjaergaard J, Lukashev D, Schreiber TH, Belikoff B, Abbott R, Sethumadhavan S, Philbrook P, Ko K, Cannici R, Thayer M, Rodig S, Kutok JL, Jackson EK, Karger B, Podack ER, Ohta A, Sitkovsky MV.

Sci Transl Med. 2015 Mar 4;7(277):277ra30. doi: 10.1126/scitranslmed.aaa1260.


Interaction of Mn with GaAs and InSb: incorporation, surface reconstruction and nano-cluster formation.

Burrows CW, Hatfield SA, Bastiman F, Bell GR.

J Phys Condens Matter. 2014 Oct 1;26(39):395006. doi: 10.1088/0953-8984/26/39/395006. Epub 2014 Sep 5.


Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection.

Hatfield SM, Kjaergaard J, Lukashev D, Belikoff B, Schreiber TH, Sethumadhavan S, Abbott R, Philbrook P, Thayer M, Shujia D, Rodig S, Kutok JL, Ren J, Ohta A, Podack ER, Karger B, Jackson EK, Sitkovsky M.

J Mol Med (Berl). 2014 Dec;92(12):1283-92. doi: 10.1007/s00109-014-1189-3. Epub 2014 Aug 15.


MHC basis of T cell-dependent heterologous immunity to arenaviruses.

Daniels KA, Hatfield SD, Welsh RM, Brehm MA.

Virology. 2014 Sep;464-465:213-217. doi: 10.1016/j.virol.2014.07.012. Epub 2014 Aug 3.


Hostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologists.

Sitkovsky MV, Hatfield S, Abbott R, Belikoff B, Lukashev D, Ohta A.

Cancer Immunol Res. 2014 Jul;2(7):598-605. doi: 10.1158/2326-6066.CIR-14-0075. Review.


Design and evaluation of xanthine based adenosine receptor antagonists: potential hypoxia targeted immunotherapies.

Thomas R, Lee J, Chevalier V, Sadler S, Selesniemi K, Hatfield S, Sitkovsky M, Ondrechen MJ, Jones GB.

Bioorg Med Chem. 2013 Dec 1;21(23):7453-64. doi: 10.1016/j.bmc.2013.09.043. Epub 2013 Sep 28.


Making assessment matter.

Hatfield SR; Joint Review Committee on Radiologic Technology.

Radiol Technol. 2013 Jul-Aug;84(6):638-41. No abstract available.


Genetic deletion of the HIF-1α isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model.

Georgiev P, Belikoff BG, Hatfield S, Ohta A, Sitkovsky MV, Lukashev D.

Eur J Immunol. 2013 Mar;43(3):655-66. doi: 10.1002/eji.201242765. Epub 2013 Jan 31.


Slipped capital femoral epiphysis in a patient with knee pain.

Hatfield SJ, Baxter RE.

J Orthop Sports Phys Ther. 2012 May;42(5):482. doi: 10.2519/jospt.2012.0408. Epub 2012 May 1. No abstract available.


A2B adenosine receptor blockade enhances macrophage-mediated bacterial phagocytosis and improves polymicrobial sepsis survival in mice.

Belikoff BG, Hatfield S, Georgiev P, Ohta A, Lukashev D, Buras JA, Remick DG, Sitkovsky M.

J Immunol. 2011 Feb 15;186(4):2444-53. doi: 10.4049/jimmunol.1001567. Epub 2011 Jan 17.


Adenosine negative feedback on A2A adenosine receptors mediates hyporesponsiveness in chronically septic mice.

Belikoff B, Hatfield S, Sitkovsky M, Remick DG.

Shock. 2011 Apr;35(4):382-7. doi: 10.1097/SHK.0b013e3182085f12.


Treatment of metastatic prostate adenocarcinoma to the calcaneus.

Bibbo C, Hatfield SP, Albright JT.

J Foot Ankle Surg. 2010 Mar-Apr;49(2):159.e15-20. doi: 10.1053/j.jfas.2009.07.027. Epub 2009 Dec 16.


Is there still a role for measuring serum urea in an age of eGFR? Evidence of its use when assessing patient hydration.

Shepherd J, Hatfield S, Kilpatrick ES.

Nephron Clin Pract. 2009;113(3):c203-6. doi: 10.1159/000233057. Epub 2009 Aug 11.


The antihypoxia-adenosinergic pathogenesis as a result of collateral damage by overactive immune cells.

Hatfield S, Belikoff B, Lukashev D, Sitkovsky M, Ohta A.

J Leukoc Biol. 2009 Sep;86(3):545-8. doi: 10.1189/jlb.0908577. Epub 2009 Jun 29. Review.


Dicer-1-dependent Dacapo suppression acts downstream of Insulin receptor in regulating cell division of Drosophila germline stem cells.

Yu JY, Reynolds SH, Hatfield SD, Shcherbata HR, Fischer KA, Ward EJ, Long D, Ding Y, Ruohola-Baker H.

Development. 2009 May;136(9):1497-507. doi: 10.1242/dev.025999. Epub 2009 Mar 31.


microRNA and stem cell function.

Hatfield S, Ruohola-Baker H.

Cell Tissue Res. 2008 Jan;331(1):57-66. Epub 2007 Nov 7. Review.


Stem cells signal to the niche through the Notch pathway in the Drosophila ovary.

Ward EJ, Shcherbata HR, Reynolds SH, Fischer KA, Hatfield SD, Ruohola-Baker H.

Curr Biol. 2006 Dec 5;16(23):2352-8. Epub 2006 Nov 2.


New cathepsin d inhibitors with hydroxyethylamine isosteres: preparation and characterization.

McConnell RM, Green AW, Trana CJ, McConnell MS, Lindley JF, Sayyar K, Godwin WE, Hatfield SE.

Med Chem. 2006 Jan;2(1):27-38.


Effects of oxandrolone on outcome measures in the severely burned: a multicenter prospective randomized double-blind trial.

Wolf SE, Edelman LS, Kemalyan N, Donison L, Cross J, Underwood M, Spence RJ, Noppenberger D, Palmieri TL, Greenhalgh DG, Lawless M, Voigt D, Edwards P, Warner P, Kagan R, Hatfield S, Jeng J, Crean D, Hunt J, Purdue G, Burris A, Cairns B, Kessler M, Klein RL, Baker R, Yowler C, Tutulo W, Foster K, Caruso D, Hildebrand B, Benjamin W, Villarreal C, Sanford AP, Saffle J.

J Burn Care Res. 2006 Mar-Apr;27(2):131-9; discussion 140-1.


The MicroRNA pathway plays a regulatory role in stem cell division.

Shcherbata HR, Hatfield S, Ward EJ, Reynolds S, Fischer KA, Ruohola-Baker H.

Cell Cycle. 2006 Jan;5(2):172-5. Epub 2006 Jan 16. Review.


Stem cell division is regulated by the microRNA pathway.

Hatfield SD, Shcherbata HR, Fischer KA, Nakahara K, Carthew RW, Ruohola-Baker H.

Nature. 2005 Jun 16;435(7044):974-8. Epub 2005 Jun 8.


Genome wide analysis of transcript levels after perturbation of the EGFR pathway in the Drosophila ovary.

Jordan KC, Hatfield SD, Tworoger M, Ward EJ, Fischer KA, Bowers S, Ruohola-Baker H.

Dev Dyn. 2005 Mar;232(3):709-24.


Seryl-histidine as an alternative DNA nicking agent in nick translation yields superior DNA probes and hybridizations.

Li Y, Hatfield S, Li J, McMills M, Zhao Y, Chen X.

Bioorg Med Chem. 2002 Mar;10(3):667-73.


Dipeptide seryl-histidine and related oligopeptides cleave DNA, protein, and a carboxyl ester.

Li Y, Zhao Y, Hatfield S, Wan R, Zhu Q, Li X, McMills M, Ma Y, Li J, Brown KL, He C, Liu F, Chen X.

Bioorg Med Chem. 2000 Dec;8(12):2675-80.


Albendazole versus praziquantel for neurocysticercosis.

Mehta SS, Hatfield S, Jessen L, Vogel D.

Am J Health Syst Pharm. 1998 Mar 15;55(6):598-600. Review. No abstract available.


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