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Practical Guidance for Clinical Microbiology Laboratories: Viruses Causing Acute Respiratory Tract Infections.

Charlton CL, Babady E, Ginocchio CC, Hatchette TF, Jerris RC, Li Y, Loeffelholz M, McCarter YS, Miller MB, Novak-Weekley S, Schuetz AN, Tang YW, Widen R, Drews SJ.

Clin Microbiol Rev. 2018 Dec 12;32(1). pii: e00042-18. doi: 10.1128/CMR.00042-18. Print 2019 Jan.


The Impact of Prior Season Vaccination on Subsequent Influenza Vaccine Effectiveness (VE) to Prevent Influenza-Related Hospitalizations over Four Influenza Seasons in Canada.

Nichols MK, Andrew MK, Ye L, Hatchette TF, Ambrose A, Boivin G, Bowie W, Dos Santos G, Elsherif M, Green K, Haguinet F, Katz K, Leblanc J, Loeb M, MacKinnon-Cameron D, McCarthy A, McElhaney JE, McGeer A, Powis J, Richardson D, Semret M, Sharma R, Shinde V, Smyth D, Trottier S, Valiquette L, Webster D, McNeil SA; Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN).

Clin Infect Dis. 2018 Dec 3. doi: 10.1093/cid/ciy1009. [Epub ahead of print]


Risk acceptance of human T-lymphotropic virus infection in solid organ transplantation-A survey of Atlantic Canadian ambulatory patients.

Patriquin G, Hatchette JE, Hatchette TF.

Transpl Infect Dis. 2018 Oct;20(5):e12958. doi: 10.1111/tid.12958. Epub 2018 Jul 20.


Influenza vaccine effectiveness to prevent influenza-related hospitalizations and serious outcomes in Canadian adults over the 2011/12 through 2013/14 influenza seasons: A pooled analysis from the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS Network).

Nichols MK, Andrew MK, Hatchette TF, Ambrose A, Boivin G, Bowie W, Chit A, Dos Santos G, ElSherif M, Green K, Haguinet F, Halperin SA, Ibarguchi B, Johnstone J, Katz K, Lagacé-Wiens P, Langley JM, LeBlanc J, Loeb M, MacKinnon-Cameron D, McCarthy A, McElhaney JE, McGeer A, Poirier A, Powis J, Richardson D, Schuind A, Semret M, Shinde V, Smith S, Smyth D, Stiver G, Taylor G, Trottier S, Valiquette L, Webster D, Ye L, McNeil SA; Serious Outcomes Surveillance Network of the Canadian Immunization Research Network (CIRN), the Toronto Invasive Bacterial Diseases Network (TIBDN).

Vaccine. 2018 Apr 12;36(16):2166-2175. doi: 10.1016/j.vaccine.2018.02.093. Epub 2018 Mar 13.


Waning of measles maternal antibody in infants in measles elimination settings - A systematic literature review.

Guerra FM, Crowcroft NS, Friedman L, Deeks SL, Halperin SA, Severini A, Hatchette TF, Bolotin S; Immunity of Canadians and Risk of Epidemics (iCARE) Network.

Vaccine. 2018 Feb 28;36(10):1248-1255. doi: 10.1016/j.vaccine.2018.01.002. Epub 2018 Feb 2. Review.


High Seroprevalence of Jamestown Canyon Virus among Deer and Humans, Nova Scotia, Canada.

Patriquin G, Drebot M, Cole T, Lindsay R, Schleihauf E, Johnston BL, Dimitrova K, Traykova-Andonova M, Mask A, Haldane D, Hatchette TF.

Emerg Infect Dis. 2018 Jan;24(1):118-121. doi: 10.3201/eid2401.170484.


Comparison of two automated instruments for Epstein-Barr virus serology in a large adult hospital and implementation of an Epstein-Barr virus nuclear antigen-based testing algorithm.

Al Sidairi H, Binkhamis K, Jackson C, Roberts C, Heinstein C, MacDonald J, Needle R, Hatchette TF, LeBlanc JJ.

J Med Microbiol. 2017 Nov;66(11):1628-1634. doi: 10.1099/jmm.0.000616. Epub 2017 Oct 16.


Assessing the diagnostic accuracy of PCR-based detection of Streptococcus pneumoniae from nasopharyngeal swabs collected for viral studies in Canadian adults hospitalised with community-acquired pneumonia: a Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research (CIRN) study.

Gillis HD, Lang ALS, ElSherif M, Martin I, Hatchette TF, McNeil SA, LeBlanc JJ; Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research (CIRN).

BMJ Open. 2017 Jun 8;7(6):e015008. doi: 10.1136/bmjopen-2016-015008.


Burden of vaccine-preventable pneumococcal disease in hospitalized adults: A Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) network study.

LeBlanc JJ, ElSherif M, Ye L, MacKinnon-Cameron D, Li L, Ambrose A, Hatchette TF, Lang AL, Gillis H, Martin I, Andrew MK, Boivin G, Bowie W, Green K, Johnstone J, Loeb M, McCarthy A, McGeer A, Moraca S, Semret M, Stiver G, Trottier S, Valiquette L, Webster D, McNeil SA; Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN).

Vaccine. 2017 Jun 22;35(29):3647-3654. doi: 10.1016/j.vaccine.2017.05.049. Epub 2017 May 26.


Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance.

Tang JW, Lam TT, Zaraket H, Lipkin WI, Drews SJ, Hatchette TF, Heraud JM, Koopmans MP; INSPIRE investigators.

Lancet Infect Dis. 2017 Oct;17(10):e320-e326. doi: 10.1016/S1473-3099(17)30238-4. Epub 2017 Apr 28. Review. Erratum in: Lancet Infect Dis. 2017 Jul;17(7):689.


Antibody responses to Borrelia burgdorferi detected by western blot vary geographically in Canada.

Ogden NH, Arsenault J, Hatchette TF, Mechai S, Lindsay LR.

PLoS One. 2017 Feb 9;12(2):e0171731. doi: 10.1371/journal.pone.0171731. eCollection 2017.


Calibration and Evaluation of Quantitative Antibody Titers for Measles Virus by Using the BioPlex 2200.

Hatchette TF, Scholz H, Bolotin S, Crowcroft NS, Jackson C, McLachlan E, Severini A.

Clin Vaccine Immunol. 2017 Jan 5;24(1). pii: e00269-16. doi: 10.1128/CVI.00269-16. Print 2017 Jan.


Comparison of monoplex and duplex RT-PCR assays for the detection of measles virus.

Binkhamis K, Gillis H, Lafreniere JD, Hiebert J, Mendoza L, Pettipas J, Severini A, Hatchette TF, LeBlanc JJ.

J Virol Methods. 2017 Jan;239:58-60. doi: 10.1016/j.jviromet.2016.11.003. Epub 2016 Nov 9.


Outbreak of Norovirus GII.P17-GII.17 in the Canadian Province of Nova Scotia.

LeBlanc JJ, Pettipas J, Gaston D, Taylor R, Hatchette TF, Booth TF, Mandes R, McDermid A, Grudeski E.

Can J Infect Dis Med Microbiol. 2016;2016:1280247. doi: 10.1155/2016/1280247. Epub 2016 May 8.


Standardization of Hemagglutination Inhibition Assay for Influenza Serology Allows for High Reproducibility between Laboratories.

Zacour M, Ward BJ, Brewer A, Tang P, Boivin G, Li Y, Warhuus M, McNeil SA, LeBlanc JJ, Hatchette TF; Public Health Agency of Canada and Canadian Institutes of Health Influenza Research Network (PCIRN).

Clin Vaccine Immunol. 2016 Jan 27;23(3):236-42. doi: 10.1128/CVI.00613-15.


Cross-reactivity between Lyme and syphilis screening assays: Lyme disease does not cause false-positive syphilis screens.

Patriquin G, LeBlanc J, Heinstein C, Roberts C, Lindsay R, Hatchette TF.

Diagn Microbiol Infect Dis. 2016 Mar;84(3):184-6. doi: 10.1016/j.diagmicrobio.2015.11.019. Epub 2015 Nov 23.


Epidemiology of Lyme Disease, Nova Scotia, Canada, 2002-2013.

Hatchette TF, Johnston BL, Schleihauf E, Mask A, Haldane D, Drebot M, Baikie M, Cole TJ, Fleming S, Gould R, Lindsay R.

Emerg Infect Dis. 2015 Oct;21(10):1751-8. doi: 10.3201/eid2110.141640.


Respiratory Outbreak Investigations: How Many Specimens Should Be Tested?

Schleihauf E, Fathima S, Pettipas J, LeBlanc JJ, Hatchette TF, Drews SJ, Haldane D.

Infect Control Hosp Epidemiol. 2015 Nov;36(11):1344-7. doi: 10.1017/ice.2015.171. Epub 2015 Jul 16.


Detection and prediction of Streptococcus pneumoniae serotypes directly from nasopharyngeal swabs using PCR.

Lang AL, McNeil SA, Hatchette TF, Elsherif M, Martin I, LeBlanc JJ.

J Med Microbiol. 2015 Aug;64(8):836-44. doi: 10.1099/jmm.0.000097. Epub 2015 Jun 11.


Against vaccine assay secrecy.

Herder M, Hatchette TF, Halperin SA, Langley JM.

Hum Vaccin Immunother. 2015;11(2):498-503. doi: 10.4161/21645515.2014.980194.


Pushing the limits of chemistry point-of-care testing for the management of patients under investigation for Ebola virus disease.

LeBlanc JJ, Heinstein C, MacDonald J, Gallant R, Roberts C, Jackson C, Lou A, Nassar BA, Hatchette TF.

Ann Clin Biochem. 2016 Mar;53(Pt 2):288-91. doi: 10.1177/0004563215581651. Epub 2015 Mar 26.


Detection of enterovirus D68 in Canadian laboratories.

Hatchette TF, Drews SJ, Grudeski E, Booth T, Martineau C, Dust K, Garceau R, Gubbay J, Karnauchow T, Krajden M, Levett PN, Mazzulli T, McDonald RR, McNabb A, Mubareka S, Needle R, Petrich A, Richardson S, Rutherford C, Smieja M, Tellier R, Tipples G, LeBlanc JJ.

J Clin Microbiol. 2015 May;53(5):1748-51. doi: 10.1128/JCM.03686-14. Epub 2015 Mar 4.


Interim estimates of 2014/15 influenza vaccine effectiveness in preventing laboratory-confirmed influenza-related hospitalisation from the Serious Outcomes Surveillance Network of the Canadian Immunization Research Network, January 2015.

McNeil SA, Andrew MK, Ye L, Haguinet F, Hatchette TF, ElSherif M, LeBlanc J, Ambrose A, McGeer A, McElhaney JE, Loeb M, MacKinnon-Cameron D, Sharma R, Dos Santos G, Shinde V; Investigators of the Serious Outcomes Surveillance Network of the Canadian Immunization Research Network (CIRN).

Euro Surveill. 2015 Feb 5;20(5):21024. No abstract available.


Zanamivir versus trivalent split virus influenza vaccine: a pilot randomized trial.

Coleman BL, Fadel SA, Drews SJ, Hatchette TF, McGeer AJ.

Influenza Other Respir Viruses. 2015 Mar;9(2):78-84. doi: 10.1111/irv.12301. Epub 2015 Jan 4.


Detection of circulating norovirus genotypes: hitting a moving target.

Rooney BL, Pettipas J, Grudeski E, Mykytczuk O, Pang XL, Booth TF, Hatchette TF, LeBlanc JJ.

Virol J. 2014 Jul 18;11:129. doi: 10.1186/1743-422X-11-129.


Influenza a virus host shutoff disables antiviral stress-induced translation arrest.

Khaperskyy DA, Emara MM, Johnston BP, Anderson P, Hatchette TF, McCormick C.

PLoS Pathog. 2014 Jul 10;10(7):e1004217. doi: 10.1371/journal.ppat.1004217. eCollection 2014 Jul.


Lyme disease: clinical diagnosis and treatment.

Hatchette TF, Davis I, Johnston BL.

Can Commun Dis Rep. 2014 May 29;40(11):194-208. eCollection 2014 May 29.


Detection and differentiation of herpes simplex viruses by use of the viper platform: advantages, limitations, and concerns.

Lang AL, Roberts C, Mazzulli T, Hatchette TF, LeBlanc JJ.

J Clin Microbiol. 2014 Jun;52(6):2186-8. doi: 10.1128/JCM.03636-13. Epub 2014 Apr 2.


Interim estimates of 2013/14 influenza clinical severity and vaccine effectiveness in the prevention of laboratory-confirmed influenza-related hospitalisation, Canada, February 2014.

McNeil S, Shinde V, Andrew M, Hatchette T, Leblanc J, Ambrose A, Boivin G, Bowie W, Diaz-Mitoma F, Elsherif M, Green K, Haguinet F, Halperin S, Ibarguchi B, Katz K, Langley J, Lagace-Wiens P, Light B, Loeb M, McElhaney J, Mackinnon-Cameron D, McCarthy A, Poirier M, Powis J, Richardson D, Semret M, Smith S, Smyth D, Stiver G, Trottier S, Valiquette L, Webster D, Ye L, McGeer A; Public Health Agency of Canada/Canadian Institutes of Health Research Influenza Research Network (PCIRN) Serious Outcomes Surveillance Network; Toronto Invasive Bacterial Diseases Network (TIBDN).

Euro Surveill. 2014 Mar 6;19(9). pii: 20729.


Molecular detection of varicella zoster virus while keeping an eye on the budget.

Binkhamis K, Al-Siyabi T, Heinstein C, Hatchette TF, LeBlanc JJ.

J Virol Methods. 2014 Jun;202:24-7. doi: 10.1016/j.jviromet.2014.02.009. Epub 2014 Mar 7.


Comparative evaluation of the Bio-Rad Geenius HIV-1/2 Confirmatory Assay and the Bio-Rad Multispot HIV-1/2 Rapid Test as an alternative differentiation assay for CLSI M53 algorithm-I.

Malloch L, Kadivar K, Putz J, Levett PN, Tang J, Hatchette TF, Kadkhoda K, Ng D, Ho J, Kim J.

J Clin Virol. 2013 Dec;58 Suppl 1:e85-91. doi: 10.1016/j.jcv.2013.08.008. Epub 2013 Aug 28.


Detection of influenza H7N9 virus: all molecular tests are not equal.

Hatchette TF, Drews SJ, Bastien N, Li Y, German G, Antonishyn N, Charest H, Mazzulli T, Fonseca K, Krajden M, Petric M, Dust K, LeBlanc JJ.

J Clin Microbiol. 2013 Nov;51(11):3835-8. doi: 10.1128/JCM.01808-13. Epub 2013 Aug 21.


A cost effective real-time PCR for the detection of adenovirus from viral swabs.

Al-Siyabi T, Binkhamis K, Wilcox M, Wong S, Pabbaraju K, Tellier R, Hatchette TF, LeBlanc JJ.

Virol J. 2013 Jun 7;10:184. doi: 10.1186/1743-422X-10-184.


Dermacase. Can you identify this condition? Secondary syphilis.

Webb AN, Langley RG, Hatchette TF.

Can Fam Physician. 2012 Apr;58(4):409-11. No abstract available.


Influenza A virus inhibits cytoplasmic stress granule formation.

Khaperskyy DA, Hatchette TF, McCormick C.

FASEB J. 2012 Apr;26(4):1629-39. doi: 10.1096/fj.11-196915. Epub 2011 Dec 27.


The role of seroepidemiology in the comprehensive surveillance of vaccine-preventable diseases.

Wilson SE, Deeks SL, Hatchette TF, Crowcroft NS.

CMAJ. 2012 Jan 10;184(1):E70-6. doi: 10.1503/cmaj.110506. Epub 2011 Nov 14. Review. No abstract available.


Homogenization with heat treatment: A cost effective alternative to nucleic acid extraction for herpes simplex virus real-time PCR from viral swabs.

LeBlanc JJ, Heinstein CR, Hatchette TF.

J Virol Methods. 2012 Jan;179(1):261-4. doi: 10.1016/j.jviromet.2011.09.018. Epub 2011 Sep 29.


Oseltamivir pharmacokinetics in morbid obesity (OPTIMO trial).

Thorne-Humphrey LM, Goralski KB, Slayter KL, Hatchette TF, Johnston BL, McNeil SA; 2009 OPTIMO Study Group.

J Antimicrob Chemother. 2011 Sep;66(9):2083-91. doi: 10.1093/jac/dkr257. Epub 2011 Jun 23.


Barriers to gender-equitable HIV testing: going beyond routine screening for pregnant women in Nova Scotia, Canada.

Gahagan JC, Fuller JL, Proctor-Simms EM, Hatchette TF, Baxter LN.

Int J Equity Health. 2011 May 11;10:18. doi: 10.1186/1475-9276-10-18.


Oseltamivir-resistant pandemic H1N1 influenza.

Webster D, Li Y, Bastien N, Garceau R, Hatchette TF.

CMAJ. 2011 Apr 19;183(7):E420-2. doi: 10.1503/cmaj.100313. Epub 2011 Feb 14. Review. No abstract available.


Nationwide molecular surveillance of pandemic H1N1 influenza A virus genomes: Canada, 2009.

Graham M, Liang B, Van Domselaar G, Bastien N, Beaudoin C, Tyler S, Kaplen B, Landry E; National Influenza A/H1N1pdm Genomics Study Team (NIGST), Li Y.

PLoS One. 2011 Jan 7;6(1):e16087. doi: 10.1371/journal.pone.0016087.


Infectious diarrhea: when to test and when to treat.

Hatchette TF, Farina D.

CMAJ. 2011 Feb 22;183(3):339-44. doi: 10.1503/cmaj.091495. Epub 2010 Dec 20. No abstract available.


Analytical performance of norovirus real-time RT-PCR detection protocols in Canadian laboratories.

Mattison K, Grudeski E, Auk B, Brassard J, Charest H, Dust K, Gubbay J, Hatchette TF, Houde A, Jean J, Jones T, Lee BE, Mamiya H, McDonald R, Mykytczuk O, Pang X, Petrich A, Plante D, Ritchie G, Wong J, Booth TF.

J Clin Virol. 2011 Feb;50(2):109-13. doi: 10.1016/j.jcv.2010.10.008. Epub 2010 Nov 10.


Mumps and ovarian cancer: modern interpretation of an historic association.

Cramer DW, Vitonis AF, Pinheiro SP, McKolanis JR, Fichorova RN, Brown KE, Hatchette TF, Finn OJ.

Cancer Causes Control. 2010 Aug;21(8):1193-201. doi: 10.1007/s10552-010-9546-1. Epub 2010 Jun 18.


Difficulty with mumps diagnosis: what is the contribution of mumps mimickers?

Hatchette TF, Mahony JB, Chong S, LeBlanc JJ.

J Clin Virol. 2009 Dec;46(4):381-3. doi: 10.1016/j.jcv.2009.09.024. Epub 2009 Oct 13.


Switching gears for an influenza pandemic: validation of a duplex reverse transcriptase PCR assay for simultaneous detection and confirmatory identification of pandemic (H1N1) 2009 influenza virus.

LeBlanc JJ, Li Y, Bastien N, Forward KR, Davidson RJ, Hatchette TF.

J Clin Microbiol. 2009 Dec;47(12):3805-13. doi: 10.1128/JCM.01344-09. Epub 2009 Sep 30.


Estimating sensitivity of laboratory testing for influenza in Canada through modelling.

Schanzer DL, Garner MJ, Hatchette TF, Langley JM, Aziz S, Tam TW.

PLoS One. 2009 Aug 18;4(8):e6681. doi: 10.1371/journal.pone.0006681.


Investigation of the first cases of human-to-human infection with the new swine-origin influenza A (H1N1) virus in Canada.

Cutler J, Schleihauf E, Hatchette TF, Billard B, Watson-Creed G, Davidson R, Li Y, Bastien N, Sarwal S; Nova Scotia Human Swine Influenza Investigation Team.

CMAJ. 2009 Aug 4;181(3-4):159-63. doi: 10.1503/cmaj.090859. Epub 2009 Jul 20.


The limitations of point of care testing for pandemic influenza: what clinicians and public health professionals need to know.

Hatchette TF, Bastien N, Berry J, Booth TF, Chernesky M, Couillard M, Drews S, Ebsworth A, Fearon M, Fonseca K, Fox J, Gagnon JN, Guercio S, Horsman G, Jorowski C, Kuschak T, Li Y, Majury A, Petric M, Ratnam S, Smieja M, Van Caeseele P; Pandemic Influenza Laboratory Preparedness Network.

Can J Public Health. 2009 May-Jun;100(3):204-7.


Laboratory diagnosis of mumps in a partially immunized population: The Nova Scotia experience.

Hatchette T, Davidson R, Clay S, Pettipas J, Leblanc J, Sarwal S, Smieja M, Forward K.

Can J Infect Dis Med Microbiol. 2009 Winter;20(4):e157-62.

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