Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 91

1.

Improving the efficiency of Monte Carlo simulations of ions using expanded grand canonical ensembles.

Hatch HW, Hall SW, Errington JR, Shen VK.

J Chem Phys. 2019 Oct 14;151(14):144109. doi: 10.1063/1.5123683.

PMID:
31615250
2.

Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING.

Siu T, Altman MD, Baltus GA, Childers M, Ellis JM, Gunaydin H, Hatch H, Ho T, Jewell J, Lacey BM, Lesburg CA, Pan BS, Sauvagnat B, Schroeder GK, Xu S.

ACS Med Chem Lett. 2018 Dec 6;10(1):92-97. doi: 10.1021/acsmedchemlett.8b00466. eCollection 2019 Jan 10.

PMID:
30655953
3.

Evaluating the Effects of Hinge Flexibility on the Solution Structure of Antibodies at Concentrated Conditions.

Blanco MA, Hatch HW, Curtis JE, Shen VK.

J Pharm Sci. 2019 May;108(5):1663-1674. doi: 10.1016/j.xphs.2018.12.013. Epub 2018 Dec 26.

PMID:
30593783
4.

Predicting structural properties of fluids by thermodynamic extrapolation.

Mahynski NA, Jiao S, Hatch HW, Blanco MA, Shen VK.

J Chem Phys. 2018 May 21;148(19):194105. doi: 10.1063/1.5026493.

5.

A methodology to calculate small-angle scattering profiles of macromolecular solutions from molecular simulations in the grand-canonical ensemble.

Blanco MA, Hatch HW, Curtis JE, Shen VK.

J Chem Phys. 2018 Aug 28;149(8):084203. doi: 10.1063/1.5029274.

PMID:
30193476
6.

Assembly of three-dimensional binary superlattices from multi-flavored particles.

Pretti E, Zerze H, Song M, Ding Y, Mahynski NA, Hatch HW, Shen VK, Mittal J.

Soft Matter. 2018 Aug 1;14(30):6303-6312. doi: 10.1039/c8sm00989a.

PMID:
30014070
7.

A Drosophila Model of Intellectual Disability Caused by Mutations in the Histone Demethylase KDM5.

Zamurrad S, Hatch HAM, Drelon C, Belalcazar HM, Secombe J.

Cell Rep. 2018 Feb 27;22(9):2359-2369. doi: 10.1016/j.celrep.2018.02.018.

8.

Communication: Predicting virial coefficients and alchemical transformations by extrapolating Mayer-sampling Monte Carlo simulations.

Hatch HW, Jiao S, Mahynski NA, Blanco MA, Shen VK.

J Chem Phys. 2017 Dec 21;147(23):231102. doi: 10.1063/1.5016165.

9.

Molecular Dynamics Simulation of Trimer Self-Assembly Under Shear.

Mountain RD, Hatch HW, Shen VK.

Fluid Phase Equilib. 2017 May 25;440:87-94. doi: 10.1016/j.fluid.2017.02.017. Epub 2017 Mar 6.

10.

Assembly of multi-flavored two-dimensional colloidal crystals.

Mahynski NA, Zerze H, Hatch HW, Shen VK, Mittal J.

Soft Matter. 2017 Aug 16;13(32):5397-5408. doi: 10.1039/c7sm01005b.

11.

Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function.

Li Q, Kellner DA, Hatch HAM, Yumita T, Sanchez S, Machold RP, Frank CA, Stavropoulos N.

PLoS Genet. 2017 May 30;13(5):e1006815. doi: 10.1371/journal.pgen.1006815. eCollection 2017 May.

12.

Depletion-driven crystallization of cubic colloids sedimented on a surface.

Hatch HW, Krekelberg WP, Hudson SD, Shen VK.

J Chem Phys. 2016 May 21;144(19):194902. doi: 10.1063/1.4949758.

13.

Self-assembly of trimer colloids: effect of shape and interaction range.

Hatch HW, Yang SY, Mittal J, Shen VK.

Soft Matter. 2016 May 14;12(18):4170-9. doi: 10.1039/c6sm00473c. Epub 2016 Apr 18.

14.

Computational study of trimer self-assembly and fluid phase behavior.

Hatch HW, Mittal J, Shen VK.

J Chem Phys. 2015 Apr 28;142(16):164901. doi: 10.1063/1.4918557.

PMID:
25933785
15.

Adrenal Development in Mice Requires GATA4 and GATA6 Transcription Factors.

Tevosian SG, Jiménez E, Hatch HM, Jiang T, Morse DA, Fox SC, Padua MB.

Endocrinology. 2015 Jul;156(7):2503-17. doi: 10.1210/en.2014-1815. Epub 2015 May 1.

16.

Combined loss of the GATA4 and GATA6 transcription factors in male mice disrupts testicular development and confers adrenal-like function in the testes.

Padua MB, Jiang T, Morse DA, Fox SC, Hatch HM, Tevosian SG.

Endocrinology. 2015 May;156(5):1873-86. doi: 10.1210/en.2014-1907. Epub 2015 Feb 10.

17.

MCL1 and BCL-xL levels in solid tumors are predictive of dinaciclib-induced apoptosis.

Booher RN, Hatch H, Dolinski BM, Nguyen T, Harmonay L, Al-Assaad AS, Ayers M, Nebozhyn M, Loboda A, Hirsch HA, Zhang T, Shi B, Merkel CE, Angagaw MH, Wang Y, Long BJ, Lennon XQ, Miselis N, Pucci V, Monahan JW, Lee J, Kondic AG, Im EK, Mauro D, Blanchard R, Gilliland G, Fawell SE, Zawel L, Schuller AG, Strack P.

PLoS One. 2014 Oct 7;9(10):e108371. doi: 10.1371/journal.pone.0108371. eCollection 2014.

18.

Computational study of the stability of the miniprotein trp-cage, the GB1 β-hairpin, and the AK16 peptide, under negative pressure.

Hatch HW, Stillinger FH, Debenedetti PG.

J Phys Chem B. 2014 Jul 17;118(28):7761-9. doi: 10.1021/jp410651u. Epub 2014 Mar 7.

PMID:
24559466
19.

Identification of a novel, non-tetrahydroquinoline variant of the cholesteryl ester transfer protein (CETP) inhibitor torcetrapib, with improved aqueous solubility.

Kalgutkar AS, Frederick KS, Hatch HL, Ambler CM, Perry DA, Garigipati RS, Chang GC, Lefker BA, Clark RW, Morehouse LA, Francone O, Hu X.

Xenobiotica. 2014 Jul;44(7):591-605. doi: 10.3109/00498254.2013.874611. Epub 2013 Dec 31.

PMID:
24380613
20.

Discovery of 1-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c-Met/Ron dual kinase inhibitor with preferential affinity for the activated state of c-Met.

Northrup AB, Katcher MH, Altman MD, Chenard M, Daniels MH, Deshmukh SV, Falcone D, Guerin DJ, Hatch H, Li C, Lu W, Lutterbach B, Allison TJ, Patel SB, Reilly JF, Reutershan M, Rickert KW, Rosenstein C, Soisson SM, Szewczak AA, Walker D, Wilson K, Young JR, Pan BS, Dinsmore CJ.

J Med Chem. 2013 Mar 28;56(6):2294-310. doi: 10.1021/jm301619u. Epub 2013 Mar 18.

PMID:
23379595
21.

Molecular modeling of mechanical stresses on proteins in glassy matrices: formalism.

Hatch HW, Debenedetti PG.

J Chem Phys. 2012 Jul 21;137(3):035103. doi: 10.1063/1.4734007.

PMID:
22830732
22.

Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src.

Alt-Holland A, Sowalsky AG, Szwec-Levin Y, Shamis Y, Hatch H, Feig LA, Garlick JA.

J Invest Dermatol. 2011 Nov;131(11):2306-15. doi: 10.1038/jid.2011.188. Epub 2011 Jun 30.

23.

Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer.

Katz JD, Jewell JP, Guerin DJ, Lim J, Dinsmore CJ, Deshmukh SV, Pan BS, Marshall CG, Lu W, Altman MD, Dahlberg WK, Davis L, Falcone D, Gabarda AE, Hang G, Hatch H, Holmes R, Kunii K, Lumb KJ, Lutterbach B, Mathvink R, Nazef N, Patel SB, Qu X, Reilly JF, Rickert KW, Rosenstein C, Soisson SM, Spencer KB, Szewczak AA, Walker D, Wang W, Young J, Zeng Q.

J Med Chem. 2011 Jun 23;54(12):4092-108. doi: 10.1021/jm200112k. Epub 2011 May 24.

PMID:
21608528
24.

Chiral symmetry breaking in a microscopic model with asymmetric autocatalysis and inhibition.

Hatch HW, Stillinger FH, Debenedetti PG.

J Chem Phys. 2010 Dec 14;133(22):224502. doi: 10.1063/1.3511715.

PMID:
21171686
25.

MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo.

Hirai H, Sootome H, Nakatsuru Y, Miyama K, Taguchi S, Tsujioka K, Ueno Y, Hatch H, Majumder PK, Pan BS, Kotani H.

Mol Cancer Ther. 2010 Jul;9(7):1956-67. doi: 10.1158/1535-7163.MCT-09-1012. Epub 2010 Jun 22.

26.

Assessing the thermodynamic signatures of hydrophobic hydration for several common water models.

Ashbaugh HS, Collett NJ, Hatch HW, Staton JA.

J Chem Phys. 2010 Mar 28;132(12):124504. doi: 10.1063/1.3366718.

PMID:
20370130
27.

Distinguishing between attributional and mnemonic sources of familiarity: the case of positive emotion bias.

Verde MF, Stone LK, Hatch HS, Schnall S.

Mem Cognit. 2010 Mar;38(2):142-53. doi: 10.3758/MC.38.2.142.

PMID:
20173187
28.

MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor.

Pan BS, Chan GK, Chenard M, Chi A, Davis LJ, Deshmukh SV, Gibbs JB, Gil S, Hang G, Hatch H, Jewell JP, Kariv I, Katz JD, Kunii K, Lu W, Lutterbach BA, Paweletz CP, Qu X, Reilly JF, Szewczak AA, Zeng Q, Kohl NE, Dinsmore CJ.

Cancer Res. 2010 Feb 15;70(4):1524-33. doi: 10.1158/0008-5472.CAN-09-2541. Epub 2010 Feb 9.

29.

Natively unfolded protein stability as a coil-to-globule transition in charge/hydropathy space.

Ashbaugh HS, Hatch HW.

J Am Chem Soc. 2008 Jul 23;130(29):9536-42. doi: 10.1021/ja802124e. Epub 2008 Jun 25.

PMID:
18576630
30.

FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.

Kunii K, Davis L, Gorenstein J, Hatch H, Yashiro M, Di Bacco A, Elbi C, Lutterbach B.

Cancer Res. 2008 Apr 1;68(7):2340-8. doi: 10.1158/0008-5472.CAN-07-5229. Erratum in: Cancer Res. 2008 May 1;68(9):3550.

31.

Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor (+)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid in rat and human.

Kalgutkar AS, Feng B, Nguyen HT, Frederick KS, Campbell SD, Hatch HL, Bi YA, Kazolias DC, Davidson RE, Mireles RJ, Duignan DB, Choo EF, Zhao SX.

Drug Metab Dispos. 2007 Nov;35(11):2111-8. Epub 2007 Aug 8.

PMID:
17686907
32.

Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival.

Lutterbach B, Zeng Q, Davis LJ, Hatch H, Hang G, Kohl NE, Gibbs JB, Pan BS.

Cancer Res. 2007 Mar 1;67(5):2081-8. Erratum in: Cancer Res. 2007 Apr 15;67(8):3987.

33.
34.

Teratoma formation leads to failure of treatment for type I diabetes using embryonic stem cell-derived insulin-producing cells.

Fujikawa T, Oh SH, Pi L, Hatch HM, Shupe T, Petersen BE.

Am J Pathol. 2005 Jun;166(6):1781-91.

35.

Disposition of cisapride appears to be influenced by P-glycoprotein in the mouse.

Choo EF, Venkatakrishnan K, Hatch HL, Rahematpura S.

Clin Pharmacol Ther. 2005 Mar;77(3):225-6. No abstract available.

PMID:
15735616
36.

The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse model.

Doran A, Obach RS, Smith BJ, Hosea NA, Becker S, Callegari E, Chen C, Chen X, Choo E, Cianfrogna J, Cox LM, Gibbs JP, Gibbs MA, Hatch H, Hop CE, Kasman IN, Laperle J, Liu J, Liu X, Logman M, Maclin D, Nedza FM, Nelson F, Olson E, Rahematpura S, Raunig D, Rogers S, Schmidt K, Spracklin DK, Szewc M, Troutman M, Tseng E, Tu M, Van Deusen JW, Venkatakrishnan K, Walens G, Wang EQ, Wong D, Yasgar AS, Zhang C.

Drug Metab Dispos. 2005 Jan;33(1):165-74. Epub 2004 Oct 22.

PMID:
15502009
37.

Adult bone marrow-derived cells trans-differentiating into insulin-producing cells for the treatment of type I diabetes.

Oh SH, Muzzonigro TM, Bae SH, LaPlante JM, Hatch HM, Petersen BE.

Lab Invest. 2004 May;84(5):607-17.

38.

SDF-1alpha/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats.

Hatch HM, Zheng D, Jorgensen ML, Petersen BE.

Cloning Stem Cells. 2002;4(4):339-51.

PMID:
12626097
39.

Mouse A6-positive hepatic oval cells also express several hematopoietic stem cell markers.

Petersen BE, Grossbard B, Hatch H, Pi L, Deng J, Scott EW.

Hepatology. 2003 Mar;37(3):632-40.

PMID:
12601361
40.

Hepatic oval 'stem' cell in liver regeneration.

Oh SH, Hatch HM, Petersen BE.

Semin Cell Dev Biol. 2002 Dec;13(6):405-9. Review.

PMID:
12468240
41.

In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells.

Yang L, Li S, Hatch H, Ahrens K, Cornelius JG, Petersen BE, Peck AB.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8078-83. Epub 2002 Jun 4.

42.

Casein zymography of calpains using a 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid-imidazole buffer.

Croall DE, Moffett K, Hatch H.

Anal Biochem. 2002 May 1;304(1):129-32. No abstract available.

PMID:
11969198
43.

A comparison of older adolescent and adult females' responses to anger-provoking situations.

Hatch H, Forgays DK.

Adolescence. 2001 Fall;36(143):557-70.

PMID:
11817636
44.

By the numbers. Health plans address risk in pregnancy.

Hatch H.

Healthplan. 1999 Jan-Feb;40(1):59-60. No abstract available.

PMID:
10351359
45.

By the numbers. Managed care highlights.

Hatch H.

Healthplan. 1998 May-Jun;39(3):115-6. No abstract available.

PMID:
10181745
46.

Pediatric sedation with intramuscular and intravenous midazolam.

Malamed SF, Quinn CL, Hatch HG.

Anesth Prog. 1989 Jul-Oct;36(4-5):155-7. No abstract available.

47.

Coordinating center follow-up in the Veterans Administration Cooperative Study of Coronary Artery Bypass Surgery.

Peduzzi P, Hatch HT, Johnson G, Charboneau A, Pritchett J, Detre K.

Control Clin Trials. 1987 Sep;8(3):190-201.

PMID:
3311637
48.

The heart of your financial information system.

Hatch HB 3rd.

Med Group Manage. 1985 Sep-Oct;32(5):8, 13. No abstract available.

PMID:
10272842
49.

A stress management program with biochemical assay.

Sinatra ST, Kurien A, Hatch H, Montano B, Camaione D.

Conn Med. 1982 Jul;46(7):370-2. No abstract available.

PMID:
7116836
50.

Metastatic carcinoma of the pancreas simulating primary bronchogenic carcinoma.

Cassiere SG, McLain DA, Emory WB, Hatch HB Jr.

Cancer. 1980 Nov 15;46(10):2319-21.

PMID:
7427873

Supplemental Content

Support Center