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Items: 1 to 50 of 197

1.

Simvastatin increases temozolomide-induced cell death by targeting the fusion of autophagosomes and lysosomes.

Shojaei S, Koleini N, Samiei E, Aghaei M, Cole LK, Alizadeh J, Islam MI, Vosoughi AR, Albokashy M, Butterfield Y, Marzban H, Xu F, Thliveris J, Kardami E, Hatch GM, Eftekharpour E, Akbari M, Hombach-Klonisch S, Klonisch T, Ghavami S.

FEBS J. 2019 Sep 23. doi: 10.1111/febs.15069. [Epub ahead of print]

PMID:
31545550
2.

Maternal resveratrol administration protects against gestational diabetes-induced glucose intolerance and islet dysfunction in the rat offspring.

Brawerman GM, Kereliuk SM, Brar N, Cole LK, Seshadri N, Pereira TJ, Xiang B, Hunt KL, Fonseca MA, Hatch GM, Doucette CA, Dolinsky VW.

J Physiol. 2019 Aug;597(16):4175-4192. doi: 10.1113/JP278082. Epub 2019 Jul 21.

PMID:
31240717
3.

Gestational Diabetes Adversely Affects Pancreatic Islet Architecture and Function in the Male Rat Offspring.

Agarwal P, Brar N, Morriseau TS, Kereliuk SM, Fonseca MA, Cole LK, Jha A, Xiang B, Hunt KL, Seshadri N, Hatch GM, Doucette CA, Dolinsky VW.

Endocrinology. 2019 Aug 1;160(8):1907-1925. doi: 10.1210/en.2019-00232.

PMID:
31237608
4.

The relationship between phospholipids and insulin resistance: From clinical to experimental studies.

Chang W, Hatch GM, Wang Y, Yu F, Wang M.

J Cell Mol Med. 2019 Feb;23(2):702-710. doi: 10.1111/jcmm.13984. Epub 2018 Nov 6. Review.

5.

Disentangling oxidation/hydrolysis reactions of brain mitochondrial cardiolipins in pathogenesis of traumatic injury.

Chao H, Anthonymuthu TS, Kenny EM, Amoscato AA, Cole LK, Hatch GM, Ji J, Kagan VE, Bayır H.

JCI Insight. 2018 Nov 2;3(21). pii: 97677. doi: 10.1172/jci.insight.97677.

6.

Statins: a new approach to combat temozolomide chemoresistance in glioblastoma.

Shojaei S, Alizadeh J, Thliveris J, Koleini N, Kardami E, Hatch GM, Xu F, Hombach-Klonisch S, Klonisch T, Ghavami S.

J Investig Med. 2018 Dec;66(8):1083-1087. doi: 10.1136/jim-2018-000874. Epub 2018 Oct 27. Review.

PMID:
30368483
7.

Increased Bioavailable Berberine Protects Against Myocardial Ischemia Reperfusion Injury Through Attenuation of NFκB and JNK Signaling Pathways.

Yu Y, Zhang M, Hu Y, Zhao Y, Teng F, Lv X, Li J, Zhang Y, Hatch GM, Chen L.

Int Heart J. 2018 Nov 28;59(6):1378-1388. doi: 10.1536/ihj.17-458. Epub 2018 Oct 10.

8.

HMGA2 as a functional antagonist of PARP1 inhibitors in tumor cells.

Hombach-Klonisch S, Kalantari F, Medapati MR, Natarajan S, Krishnan SN, Kumar-Kanojia A, Thanasupawat T, Begum F, Xu FY, Hatch GM, Los M, Klonisch T.

Mol Oncol. 2019 Feb;13(2):153-170. doi: 10.1002/1878-0261.12390. Epub 2018 Nov 28.

9.

Misoprostol regulates Bnip3 repression and alternative splicing to control cellular calcium homeostasis during hypoxic stress.

Field JT, Martens MD, Mughal W, Hai Y, Chapman D, Hatch GM, Ivanco TL, Diehl-Jones W, Gordon JW.

Cell Death Discov. 2018 Sep 21;4:37. doi: 10.1038/s41420-018-0104-z. eCollection 2018. Erratum in: Cell Death Discov. 2019 Jul 10;5:116.

10.

MiR27a Promotes the Development of Macrophage-like Characteristics in 3T3-L1 Preadipocytes.

Zhang M, Sheng S, Zhang W, Zhang J, Zhang Z, Zhang M, Hatch GM, Chen L.

Int J Biol Sci. 2018 Sep 7;14(11):1599-1609. doi: 10.7150/ijbs.26274. eCollection 2018.

11.

Aberrant cardiolipin metabolism is associated with cognitive deficiency and hippocampal alteration in tafazzin knockdown mice.

Cole LK, Kim JH, Amoscato AA, Tyurina YY, Bay R H, Karimi B, Siddiqui TJ, Kagan VE, Hatch GM, Kauppinen TM.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3353-3367. doi: 10.1016/j.bbadis.2018.07.022. Epub 2018 Jul 25.

12.

Phosphokinome Analysis of Barth Syndrome Lymphoblasts Identify Novel Targets in the Pathophysiology of the Disease.

Agarwal P, Cole LK, Chandrakumar A, Hauff KD, Ravandi A, Dolinsky VW, Hatch GM.

Int J Mol Sci. 2018 Jul 12;19(7). pii: E2026. doi: 10.3390/ijms19072026.

13.

TAPP Adaptors Control B Cell Metabolism by Modulating the Phosphatidylinositol 3-Kinase Signaling Pathway: A Novel Regulatory Circuit Preventing Autoimmunity.

Jayachandran N, Mejia EM, Sheikholeslami K, Sher AA, Hou S, Hatch GM, Marshall AJ.

J Immunol. 2018 Jul 15;201(2):406-416. doi: 10.4049/jimmunol.1701440. Epub 2018 Jun 8.

14.

Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle Through Repression of PPARγ.

Yu Y, Du H, Wei S, Feng L, Li J, Yao F, Zhang M, Hatch GM, Chen L.

Theranostics. 2018 Mar 8;8(8):2171-2188. doi: 10.7150/thno.22565. eCollection 2018.

15.

Expression of human monolysocardiolipin acyltransferase-1 improves mitochondrial function in Barth syndrome lymphoblasts.

Mejia EM, Zegallai H, Bouchard ED, Banerji V, Ravandi A, Hatch GM.

J Biol Chem. 2018 May 18;293(20):7564-7577. doi: 10.1074/jbc.RA117.001024. Epub 2018 Mar 21.

16.

Myocardin regulates mitochondrial calcium homeostasis and prevents permeability transition.

Mughal W, Martens M, Field J, Chapman D, Huang J, Rattan S, Hai Y, Cheung KG, Kereliuk S, West AR, Cole LK, Hatch GM, Diehl-Jones W, Keijzer R, Dolinsky VW, Dixon IM, Parmacek MS, Gordon JW.

Cell Death Differ. 2018 Nov;25(10):1732-1748. doi: 10.1038/s41418-018-0073-z. Epub 2018 Mar 6.

17.

The Role of Postmortem Computed Tomography in the Evaluation of Strangulation Deaths.

Decker LA, Hatch GM, Lathrop SL, Nolte KB.

J Forensic Sci. 2018 Sep;63(5):1401-1405. doi: 10.1111/1556-4029.13760. Epub 2018 Feb 21.

PMID:
29464693
18.

The natural history of phytosterolemia: Observations on its homeostasis.

Mymin D, Salen G, Triggs-Raine B, Waggoner DJ, Dembinski T, Hatch GM.

Atherosclerosis. 2018 Feb;269:122-128. doi: 10.1016/j.atherosclerosis.2017.12.024. Epub 2017 Dec 28.

PMID:
29353227
19.

Comparative radiologic identification with standardized single CT images of the paranasal sinuses-Evaluation of inter-rater reliability.

Brun CN, Christensen AM, Kravarski M, Gorincour G, Schweitzer W, Thali MJ, Gascho D, Hatch GM, Ruder TD.

Forensic Sci Int. 2017 Nov;280:81-86. doi: 10.1016/j.forsciint.2017.08.029. Epub 2017 Sep 2.

PMID:
28961444
20.

Berberine Inhibits Oxygen Consumption Rate Independent of Alteration in Cardiolipin Levels in H9c2 Cells.

Chang W, Zhang M, Chen L, Hatch GM.

Lipids. 2017 Nov;52(11):961-967. doi: 10.1007/s11745-017-4300-z. Epub 2017 Sep 23.

PMID:
28942573
21.

Accuracy of non-contrast PMCT for determining cause of death.

Ampanozi G, Thali YA, Schweitzer W, Hatch GM, Ebert LC, Thali MJ, Ruder TD.

Forensic Sci Med Pathol. 2017 Sep;13(3):284-292. doi: 10.1007/s12024-017-9878-1. Epub 2017 Jun 15.

PMID:
28616810
22.

Antemortem identification by fusion of MR and CT of the paranasal sinuses.

Heimer J, Gascho D, Gentile S, Hatch GM, Thali MJ, Ruder TD.

Forensic Sci Med Pathol. 2017 Sep;13(3):375-378. doi: 10.1007/s12024-017-9873-6. Epub 2017 May 20.

PMID:
28526949
23.

Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.

Alizadeh J, Zeki AA, Mirzaei N, Tewary S, Rezaei Moghadam A, Glogowska A, Nagakannan P, Eftekharpour E, Wiechec E, Gordon JW, Xu FY, Field JT, Yoneda KY, Kenyon NJ, Hashemi M, Hatch GM, Hombach-Klonisch S, Klonisch T, Ghavami S.

Sci Rep. 2017 Mar 27;7:44841. doi: 10.1038/srep44841.

24.

EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells.

Mutz CN, Schwentner R, Aryee DNT, Bouchard EDJ, Mejia EM, Hatch GM, Kauer MO, Katschnig AM, Ban J, Garten A, Alonso J, Banerji V, Kovar H.

Oncotarget. 2017 Apr 11;8(15):24679-24693. doi: 10.18632/oncotarget.14976.

25.

Glucose Uptake and Triacylglycerol Synthesis Are Increased in Barth Syndrome Lymphoblasts.

Mejia EM, Zinko JC, Hauff KD, Xu FY, Ravandi A, Hatch GM.

Lipids. 2017 Feb;52(2):161-165. doi: 10.1007/s11745-017-4232-7. Epub 2017 Jan 17.

PMID:
28097490
26.

A new method for estimating patient body weight using CT dose modulation data.

Gascho D, Ganzoni L, Kolly P, Zoelch N, Hatch GM, Thali MJ, Ruder TD.

Eur Radiol Exp. 2017;1(1):23. doi: 10.1186/s41747-017-0028-z. Epub 2017 Dec 4.

27.

Erratum. Impaired Cardiolipin Biosynthesis Prevents Hepatic Steatosis and Diet-Induced Obesity. Diabetes 2016;65:3289-3300.

Cole LK, Mejia EM, Vandel M, Sparagna GC, Claypool SM, Dyck-Chan L, Klein J, Hatch GM.

Diabetes. 2017 Jan;66(1):231. doi: 10.2337/db17-er01a. Epub 2016 Nov 17. No abstract available.

28.

Comparative Evaluation of Potentially Radiolucent Projectile Components by Radiographs and Computed Tomography.

Miller CR, Haag M, Gerrard C, Hatch GM, Elifritz J, Simmons MC, Lathrop S, Nolte KB.

J Forensic Sci. 2016 Nov;61(6):1563-1570. doi: 10.1111/1556-4029.13225. Epub 2016 Oct 27.

PMID:
27787896
29.

Diacylglycerol kinase epsilon suppresses expression of p53 and glycerol kinase in mouse embryo fibroblasts.

So V, Jalan D, Lemaire M, Topham MK, Hatch GM, Epand RM.

Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):1993-1999. doi: 10.1016/j.bbalip.2016.09.021. Epub 2016 Oct 3.

PMID:
27713003
30.

Is There Enhanced Risk of Cerebral Ischemic Stroke by Sulfonylureas in Type 2 Diabetes?

Parkinson FE, Hatch GM.

Diabetes. 2016 Sep;65(9):2479-81. doi: 10.2337/dbi16-0037. No abstract available.

31.

Impaired Cardiolipin Biosynthesis Prevents Hepatic Steatosis and Diet-Induced Obesity.

Cole LK, Mejia EM, Vandel M, Sparagna GC, Claypool SM, Dyck-Chan L, Klein J, Hatch GM.

Diabetes. 2016 Nov;65(11):3289-3300. Epub 2016 Aug 5. Erratum in: Diabetes. 2017 Jan;66(1):231.

32.

Reduction in cardiolipin decreases mitochondrial spare respiratory capacity and increases glucose transport into and across human brain cerebral microvascular endothelial cells.

Nguyen HM, Mejia EM, Chang W, Wang Y, Watson E, On N, Miller DW, Hatch GM.

J Neurochem. 2016 Oct;139(1):68-80. doi: 10.1111/jnc.13753. Epub 2016 Sep 4.

33.

Distal tibia allograft for glenohumeral instability: does radius of curvature match?

Decker MM, Strohmeyer GC, Wood JP, Hatch GM, Qualls CR, Treme GP, Benson EC.

J Shoulder Elbow Surg. 2016 Sep;25(9):1542-8. doi: 10.1016/j.jse.2016.01.023. Epub 2016 Apr 7.

PMID:
27068384
34.

Berberine Attenuates Development of the Hepatic Gluconeogenesis and Lipid Metabolism Disorder in Type 2 Diabetic Mice and in Palmitate-Incubated HepG2 Cells through Suppression of the HNF-4α miR122 Pathway.

Wei S, Zhang M, Yu Y, Lan X, Yao F, Yan X, Chen L, Hatch GM.

PLoS One. 2016 Mar 24;11(3):e0152097. doi: 10.1371/journal.pone.0152097. eCollection 2016.

35.

Cardiac mitochondrial energy metabolism in heart failure: Role of cardiolipin and sirtuins.

Dolinsky VW, Cole LK, Sparagna GC, Hatch GM.

Biochim Biophys Acta. 2016 Oct;1861(10):1544-54. doi: 10.1016/j.bbalip.2016.03.008. Epub 2016 Mar 10. Review.

PMID:
26972373
36.

Pretreatment of rats with increased bioavailable berberine attenuates cerebral ischemia-reperfusion injury via down regulation of adenosine-5'monophosphate kinase activity.

Chen W, Wei S, Yu Y, Xue H, Yao F, Zhang M, Xiao J, Hatch GM, Chen L.

Eur J Pharmacol. 2016 May 15;779:80-90. doi: 10.1016/j.ejphar.2016.03.015. Epub 2016 Mar 5.

PMID:
26957053
37.

Reduced Mitochondrial Function in Human Huntington Disease Lymphoblasts is Not Due to Alterations in Cardiolipin Metabolism or Mitochondrial Supercomplex Assembly.

Mejia EM, Chau S, Sparagna GC, Sipione S, Hatch GM.

Lipids. 2016 May;51(5):561-9. doi: 10.1007/s11745-015-4110-0. Epub 2016 Feb 4.

PMID:
26846325
38.

Berberine Pretreatment Confers Cardioprotection Against Ischemia-Reperfusion Injury in a Rat Model of Type 2 Diabetes.

Chang W, Li K, Guan F, Yao F, Yu Y, Zhang M, Hatch GM, Chen L.

J Cardiovasc Pharmacol Ther. 2016 Sep;21(5):486-94. doi: 10.1177/1074248415627873. Epub 2016 Feb 4.

PMID:
26846272
39.

Berberine treatment attenuates the palmitate-mediated inhibition of glucose uptake and consumption through increased 1,2,3-triacyl-sn-glycerol synthesis and accumulation in H9c2 cardiomyocytes.

Chang W, Chen L, Hatch GM.

Biochim Biophys Acta. 2016 Apr;1861(4):352-62. doi: 10.1016/j.bbalip.2015.12.017. Epub 2016 Jan 7.

PMID:
26774040
40.

Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells.

Peyta L, Jarnouen K, Pinault M, Guimaraes C, Pais de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S.

Biochim Biophys Acta. 2016 Apr;1857(4):443-53. doi: 10.1016/j.bbabio.2016.01.002. Epub 2016 Jan 6.

41.

Postmortem magnetic resonance imaging: Reproducing typical autopsy heart measurements.

Ampanozi G, Hatch GM, Flach PM, Thali MJ, Ruder TD.

Leg Med (Tokyo). 2015 Nov;17(6):493-8. doi: 10.1016/j.legalmed.2015.10.008. Epub 2015 Oct 23.

PMID:
26593996
42.

Berberine treatment prevents cardiac dysfunction and remodeling through activation of 5'-adenosine monophosphate-activated protein kinase in type 2 diabetic rats and in palmitate-induced hypertrophic H9c2 cells.

Chang W, Zhang M, Meng Z, Yu Y, Yao F, Hatch GM, Chen L.

Eur J Pharmacol. 2015 Dec 15;769:55-63. doi: 10.1016/j.ejphar.2015.10.043. Epub 2015 Oct 30.

PMID:
26522928
43.

A conserved MADS-box phosphorylation motif regulates differentiation and mitochondrial function in skeletal, cardiac, and smooth muscle cells.

Mughal W, Nguyen L, Pustylnik S, da Silva Rosa SC, Piotrowski S, Chapman D, Du M, Alli NS, Grigull J, Halayko AJ, Aliani M, Topham MK, Epand RM, Hatch GM, Pereira TJ, Kereliuk S, McDermott JC, Rampitsch C, Dolinsky VW, Gordon JW.

Cell Death Dis. 2015 Oct 29;6:e1944. doi: 10.1038/cddis.2015.306.

44.

Generation of Bioactive Oxylipins from Exogenously Added Arachidonic, Eicosapentaenoic and Docosahexaenoic Acid in Primary Human Brain Microvessel Endothelial Cells.

Aukema HM, Winter T, Ravandi A, Dalvi S, Miller DW, Hatch GM.

Lipids. 2016 May;51(5):591-9. doi: 10.1007/s11745-015-4074-0. Epub 2015 Oct 6.

PMID:
26439837
45.

Stemming the tide of type 2 diabetes in youth: DREAMing big, one sandbag at a time.

McGavock J, Hatch GM.

Biochem Cell Biol. 2015 Oct;93(5):423-4. doi: 10.1139/bcb-2015-0116. Epub 2015 Sep 28. No abstract available.

PMID:
26412452
46.

Regulation of hepatic cardiolipin metabolism by TNFα: Implication in cancer cachexia.

Peyta L, Jarnouen K, Pinault M, Coulouarn C, Guimaraes C, Goupille C, de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S.

Biochim Biophys Acta. 2015 Nov;1851(11):1490-500. doi: 10.1016/j.bbalip.2015.08.008. Epub 2015 Sep 13.

47.
48.

Maternal obesity characterized by gestational diabetes increases the susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome.

Pereira TJ, Fonseca MA, Campbell KE, Moyce BL, Cole LK, Hatch GM, Doucette CA, Klein J, Aliani M, Dolinsky VW.

J Physiol. 2015 Jul 15;593(14):3181-97. doi: 10.1113/JP270429. Epub 2015 Jun 12.

49.

Exogenous arachidonic acid mediates permeability of human brain microvessel endothelial cells through prostaglandin E2 activation of EP3 and EP4 receptors.

Dalvi S, Nguyen HH, On N, Mitchell RW, Aukema HM, Miller DW, Hatch GM.

J Neurochem. 2015 Dec;135(5):867-79. doi: 10.1111/jnc.13117. Epub 2015 Apr 27.

50.

Erratum to: Mitochondrial phospholipids: role in mitochondrial function.

Mejia EM, Hatch GM.

J Bioenerg Biomembr. 2015 Jun;47(3):279-80. doi: 10.1007/s10863-015-9607-y. No abstract available.

PMID:
25779753

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