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Items: 1 to 50 of 118


Rock-paper-scissors: Engineered population dynamics increase genetic stability.

Liao MJ, Din MO, Tsimring L, Hasty J.

Science. 2019 Sep 6;365(6457):1045-1049. doi: 10.1126/science.aaw0542.


Divergent Aging of Isogenic Yeast Cells Revealed through Single-Cell Phenotypic Dynamics.

Jin M, Li Y, O'Laughlin R, Bittihn P, Pillus L, Tsimring LS, Hasty J, Hao N.

Cell Syst. 2019 Mar 27;8(3):242-253.e3. doi: 10.1016/j.cels.2019.02.002. Epub 2019 Mar 6.


Flavin-based metabolic cycles are integral features of growth and division in single yeast cells.

Baumgartner BL, O'Laughlin R, Jin M, Tsimring LS, Hao N, Hasty J.

Sci Rep. 2018 Dec 21;8(1):18045. doi: 10.1038/s41598-018-35936-w.


Microfluidics-Based Analysis of Contact-dependent Bacterial Interactions.

Cooper R, Tsimring L, Hasty J.

Bio Protoc. 2018 Aug 20;8(16). pii: e2970. doi: 10.21769/BioProtoc.2970.


Anxiety and Drinking: Are Personal Beliefs Regarding Control and Unpredictability Relevant?

Thomson Ross L, Hasty J.

J Psychol. 2018;152(8):646-668. doi: 10.1080/00223980.2018.1495606. Epub 2018 Oct 26.


Validation of a Sequential Hide-On Bob Veal Carcass Antimicrobial Intervention Composed of a Hot Water Wash and Lactic Acid Spray in Combination with Scalding To Control Shiga Toxin-Producing Escherichia coli Surrogates.

Hasty JD, Henson JA, Acuff GR, Burson DE, Luchansky JB, Sevart NJ, Phebus RK, Porto-Fett ACS, Thippareddi H.

J Food Prot. 2018 May;81(5):762-768. doi: 10.4315/0362-028X.JFP-17-403.


Rational engineering of synthetic microbial systems: from single cells to consortia.

Bittihn P, Din MO, Tsimring LS, Hasty J.

Curr Opin Microbiol. 2018 Oct;45:92-99. doi: 10.1016/j.mib.2018.02.009. Epub 2018 Mar 22. Review.


Inter-species population dynamics enhance microbial horizontal gene transfer and spread of antibiotic resistance.

Cooper RM, Tsimring L, Hasty J.

Elife. 2017 Nov 1;6. pii: e25950. doi: 10.7554/eLife.25950.


Multigenerational silencing dynamics control cell aging.

Li Y, Jin M, O'Laughlin R, Bittihn P, Tsimring LS, Pillus L, Hasty J, Hao N.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11253-11258. doi: 10.1073/pnas.1703379114. Epub 2017 Oct 3.


Rapid and Scalable Preparation of Bacterial Lysates for Cell-Free Gene Expression.

Didovyk A, Tonooka T, Tsimring L, Hasty J.

ACS Synth Biol. 2017 Dec 15;6(12):2198-2208. doi: 10.1021/acssynbio.7b00253. Epub 2017 Aug 21.


National Beef Quality Audit-2016: In-plant survey of carcass characteristics related to quality, quantity, and value of fed steers and heifers.

Boykin CA, Eastwood LC, Harris MK, Hale DS, Kerth CR, Griffin DB, Arnold AN, Hasty JD, Belk KE, Woerner DR, Delmore RJ, Martin JN, VanOverbeke DL, Mafi GG, Pfeiffer MM, Lawrence TE, McEvers TJ, Schmidt TB, Maddock RJ, Johnson DD, Carr CC, Scheffler JM, Pringle TD, Stelzleni AM, Gottlieb J, Savell JW.

J Anim Sci. 2017 Jul;95(7):2993-3002. doi: 10.2527/jas.2017.1543.


National Beef Quality Audit - 2016: Survey of carcass characteristics through instrument grading assessments.

Boykin CA, Eastwood LC, Harris MK, Hale DS, Kerth CR, Griffin DB, Arnold AN, Hasty JD, Belk KE, Woerner DR, Delmore RJ, Martin JN, VanOverbeke DL, Mafi GG, Pfeiffer MM, Lawrence TE, McEvers TJ, Schmidt TB, Maddock RJ, Johnson DD, Carr CC, Scheffler JM, Pringle TD, Stelzleni AM, Gottlieb J, Savell JW.

J Anim Sci. 2017 Jul;95(7):3003-3011. doi: 10.2527/jas.2017.1544.


Synchronized DNA cycling across a bacterial population.

Baumgart L, Mather W, Hasty J.

Nat Genet. 2017 Aug;49(8):1282-1285. doi: 10.1038/ng.3915. Epub 2017 Jul 10.


A stabilized microbial ecosystem of self-limiting bacteria using synthetic quorum-regulated lysis.

Scott SR, Din MO, Bittihn P, Xiong L, Tsimring LS, Hasty J.

Nat Microbiol. 2017 Jun 12;2:17083. doi: 10.1038/nmicrobiol.2017.83.


Tiger on the prowl: Invasion history and spatio-temporal genetic structure of the Asian tiger mosquito Aedes albopictus (Skuse 1894) in the Indo-Pacific.

Maynard AJ, Ambrose L, Cooper RD, Chow WK, Davis JB, Muzari MO, van den Hurk AF, Hall-Mendelin S, Hasty JM, Burkot TR, Bangs MJ, Reimer LJ, Butafa C, Lobo NF, Syafruddin D, Maung Maung YN, Ahmad R, Beebe NW.

PLoS Negl Trop Dis. 2017 Apr 14;11(4):e0005546. doi: 10.1371/journal.pntd.0005546. eCollection 2017 Apr.


Suppression of Beneficial Mutations in Dynamic Microbial Populations.

Bittihn P, Hasty J, Tsimring LS.

Phys Rev Lett. 2017 Jan 13;118(2):028102. doi: 10.1103/PhysRevLett.118.028102. Epub 2017 Jan 12.


An evaluation of the effectiveness of FreshCase technology to extend the storage life of whole-muscle pork and ground pork sausage.

Yang X, Woerner DR, McCullough KR, Hasty JD, Geornaras I, Smith GC, Sofos JN, Belk KE.

J Anim Sci. 2016 Nov;94(11):4921-4929. doi: 10.2527/jas.2016-0509.


An evaluation of the effectiveness of FreshCase technology to extend the storage life of whole muscle beef and ground beef.

Yang X, Woerner DR, Hasty JD, McCullough KR, Geornaras I, Sofos JN, Belk KE.

J Anim Sci. 2016 Nov;94(11):4911-4920. doi: 10.2527/jas.2016-0508.


FBB: a fast Bayesian-bound tool to calibrate RNA-seq aligners.

Rodriguez-Lujan I, Hasty J, Huerta R.

Bioinformatics. 2017 Jan 15;33(2):210-218. doi: 10.1093/bioinformatics/btw608. Epub 2016 Sep 23.


Criticality and Adaptivity in Enzymatic Networks.

Steiner PJ, Williams RJ, Hasty J, Tsimring LS.

Biophys J. 2016 Sep 6;111(5):1078-87. doi: 10.1016/j.bpj.2016.07.036.


Correction: Turing Patterning Using Gene Circuits with Gas-Induced Degradation of Quorum Sensing Molecules.

Borek B, Hasty J, Tsimring L.

PLoS One. 2016 Jul 28;11(7):e0160272. doi: 10.1371/journal.pone.0160272. eCollection 2016.


Synchronized cycles of bacterial lysis for in vivo delivery.

Din MO, Danino T, Prindle A, Skalak M, Selimkhanov J, Allen K, Julio E, Atolia E, Tsimring LS, Bhatia SN, Hasty J.

Nature. 2016 Aug 4;536(7614):81-85. doi: 10.1038/nature18930. Epub 2016 Jul 20.


Transcriptional regulation with CRISPR-Cas9: principles, advances, and applications.

Didovyk A, Borek B, Tsimring L, Hasty J.

Curr Opin Biotechnol. 2016 Aug;40:177-184. doi: 10.1016/j.copbio.2016.06.003. Epub 2016 Jun 23. Review.


Quorum Sensing Communication Modules for Microbial Consortia.

Scott SR, Hasty J.

ACS Synth Biol. 2016 Sep 16;5(9):969-77. doi: 10.1021/acssynbio.5b00286. Epub 2016 May 19.


Posttranscriptional Regulation of Gcr1 Expression and Activity Is Crucial for Metabolic Adjustment in Response to Glucose Availability.

Hossain MA, Claggett JM, Edwards SR, Shi A, Pennebaker SL, Cheng MY, Hasty J, Johnson TL.

Mol Cell. 2016 May 5;62(3):346-358. doi: 10.1016/j.molcel.2016.04.012.


Turing Patterning Using Gene Circuits with Gas-Induced Degradation of Quorum Sensing Molecules.

Borek B, Hasty J, Tsimring L.

PLoS One. 2016 May 5;11(5):e0153679. doi: 10.1371/journal.pone.0153679. eCollection 2016. Erratum in: PLoS One. 2016;11(7):e0160272.


Orthogonal Modular Gene Repression in Escherichia coli Using Engineered CRISPR/Cas9.

Didovyk A, Borek B, Hasty J, Tsimring L.

ACS Synth Biol. 2016 Jan 15;5(1):81-8. doi: 10.1021/acssynbio.5b00147. Epub 2015 Sep 30.


A Microfluidic Platform for Long-Term Monitoring of Algae in a Dynamic Environment.

Luke CS, Selimkhanov J, Baumgart L, Cohen SE, Golden SS, Cookson NA, Hasty J.

ACS Synth Biol. 2016 Jan 15;5(1):8-14. doi: 10.1021/acssynbio.5b00094. Epub 2015 Sep 15.


Programmable probiotics for detection of cancer in urine.

Danino T, Prindle A, Kwong GA, Skalak M, Li H, Allen K, Hasty J, Bhatia SN.

Sci Transl Med. 2015 May 27;7(289):289ra84. doi: 10.1126/scitranslmed.aaa3519.


Borrelia burgdorferi sensu lato spirochetes in wild birds in northwestern California: associations with ecological factors, bird behavior and tick infestation.

Newman EA, Eisen L, Eisen RJ, Fedorova N, Hasty JM, Vaughn C, Lane RS.

PLoS One. 2015 Feb 25;10(2):e0118146. doi: 10.1371/journal.pone.0118146. eCollection 2015.


Distributed classifier based on genetically engineered bacterial cell cultures.

Didovyk A, Kanakov OI, Ivanchenko MV, Hasty J, Huerta R, Tsimring L.

ACS Synth Biol. 2015 Jan 16;4(1):72-82. doi: 10.1021/sb500235p. Epub 2014 Nov 11.


Synchronization of degrade-and-fire oscillations via a common activator.

Mather W, Hasty J, Tsimring LS.

Phys Rev Lett. 2014 Sep 19;113(12):128102. Epub 2014 Sep 16.


Dynamic localization of the cyanobacterial circadian clock proteins.

Cohen SE, Erb ML, Selimkhanov J, Dong G, Hasty J, Pogliano J, Golden SS.

Curr Biol. 2014 Aug 18;24(16):1836-44. doi: 10.1016/j.cub.2014.07.036. Epub 2014 Aug 7.


In-vivo real-time control of protein expression from endogenous and synthetic gene networks.

Menolascina F, Fiore G, Orabona E, De Stefano L, Ferry M, Hasty J, di Bernardo M, di Bernardo D.

PLoS Comput Biol. 2014 May 15;10(5):e1003625. doi: 10.1371/journal.pcbi.1003625. eCollection 2014 May.


Rapid and tunable post-translational coupling of genetic circuits.

Prindle A, Selimkhanov J, Li H, Razinkov I, Tsimring LS, Hasty J.

Nature. 2014 Apr 17;508(7496):387-91. doi: 10.1038/nature13238. Epub 2014 Apr 9.


Measuring growth and gene expression dynamics of tumor-targeted S. typhimurium bacteria.

Danino T, Prindle A, Hasty J, Bhatia S.

J Vis Exp. 2013 Jul 6;(77):e50540. doi: 10.3791/50540.


Measuring competitive fitness in dynamic environments.

Razinkov IA, Baumgartner BL, Bennett MR, Tsimring LS, Hasty J.

J Phys Chem B. 2013 Oct 24;117(42):13175-81. doi: 10.1021/jp403162v. Epub 2013 Aug 7.


Dual delayed feedback provides sensitivity and robustness to the NF-κB signaling module.

Longo DM, Selimkhanov J, Kearns JD, Hasty J, Hoffmann A, Tsimring LS.

PLoS Comput Biol. 2013;9(6):e1003112. doi: 10.1371/journal.pcbi.1003112. Epub 2013 Jun 27.


Translational cross talk in gene networks.

Mather WH, Hasty J, Tsimring LS, Williams RJ.

Biophys J. 2013 Jun 4;104(11):2564-72. doi: 10.1016/j.bpj.2013.04.049.


Engineered microbes for therapeutic applications.

Hasty J.

ACS Synth Biol. 2012 Oct 19;1(10):438-9. doi: 10.1021/sb300105b. No abstract available.


In Vivo Gene Expression Dynamics of Tumor-Targeted Bacteria.

Danino T, Lo J, Prindle A, Hasty J, Bhatia SN.

ACS Synth Biol. 2012 Oct 19;1(10):465-470. Epub 2012 Sep 21.


Genetic Circuits in Salmonella typhimurium.

Prindle A, Selimkhanov J, Danino T, Samayoa P, Goldberg A, Bhatia SN, Hasty J.

ACS Synth Biol. 2012 Oct 19;1(10):458-464. Epub 2012 Aug 9.


Making gene circuits sing.

Prindle A, Hasty J.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16758-9. doi: 10.1073/pnas.1214118109. Epub 2012 Oct 1. No abstract available.


Vacuum-assisted cell loading enables shear-free mammalian microfluidic culture.

Kolnik M, Tsimring LS, Hasty J.

Lab Chip. 2012 Nov 21;12(22):4732-7. doi: 10.1039/c2lc40569e.


Management of contaminated open fractures: a comparison of two types of irrigation in a porcine model.

Gaines RJ, DeMaio M, Peters D, Hasty J, Blanks J.

J Trauma Acute Care Surg. 2012 Mar;72(3):733-6. doi: 10.1097/TA.0b013e318239caaf.


Fast stochastic algorithm for simulating evolutionary population dynamics.

Mather WH, Hasty J, Tsimring LS.

Bioinformatics. 2012 May 1;28(9):1230-8. doi: 10.1093/bioinformatics/bts130. Epub 2012 Mar 21.


Queueing up for enzymatic processing: correlated signaling through coupled degradation.

Cookson NA, Mather WH, Danino T, Mondragón-Palomino O, Williams RJ, Tsimring LS, Hasty J.

Mol Syst Biol. 2011 Dec 20;7:561. doi: 10.1038/msb.2011.94.


A sensing array of radically coupled genetic 'biopixels'.

Prindle A, Samayoa P, Razinkov I, Danino T, Tsimring LS, Hasty J.

Nature. 2011 Dec 18;481(7379):39-44. doi: 10.1038/nature10722.


Antagonistic gene transcripts regulate adaptation to new growth environments.

Baumgartner BL, Bennett MR, Ferry M, Johnson TL, Tsimring LS, Hasty J.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21087-92. doi: 10.1073/pnas.1111408109. Epub 2011 Dec 12.

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