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Items: 1 to 50 of 101

1.

CD8+ T cells regulate liver injury in obesity-related nonalcoholic fatty liver disease.

Breuer DA, Pacheco MC, Washington MK, Montgomery SA, Hasty AH, Kennedy AJ.

Am J Physiol Gastrointest Liver Physiol. 2020 Feb 1;318(2):G211-G224. doi: 10.1152/ajpgi.00040.2019. Epub 2019 Nov 11.

PMID:
31709830
2.

Impaired insulin signaling in the B10.D2-Hc0 H2d H2-T18c/oSnJ mouse model of complement factor 5 deficiency.

Peterson KR, Gutierrez DA, Kikuchi T, Anderson-Baucum EK, Winn NC, Shuey MM, Bolus WR, McGuinness OP, Hasty AH.

Am J Physiol Endocrinol Metab. 2019 Aug 1;317(2):E200-E211. doi: 10.1152/ajpendo.00042.2019. Epub 2019 May 14.

PMID:
31084499
3.

Extrinsic and Intrinsic Immunometabolism Converge: Perspectives on Future Research and Therapeutic Development for Obesity.

Caslin HL, Hasty AH.

Curr Obes Rep. 2019 Sep;8(3):210-219. doi: 10.1007/s13679-019-00344-2. Review.

PMID:
30919312
4.

Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor-/- Mice Improves Indices of Cardiometabolic Disease.

May-Zhang LS, Chen Z, Dosoky NS, Yancey PG, Boyd KL, Hasty AH, Linton MF, Davies SS.

Sci Rep. 2019 Jan 23;9(1):420. doi: 10.1038/s41598-018-37373-1.

5.

Obesity-induced reduction of adipose eosinophils is reversed with low-calorie dietary intervention.

Bolus WR, Kennedy AJ, Hasty AH.

Physiol Rep. 2018 Nov;6(22):e13919. doi: 10.14814/phy2.13919.

6.

High CD8 T-Cell Receptor Clonality and Altered CDR3 Properties Are Associated With Elevated Isolevuglandins in Adipose Tissue During Diet-Induced Obesity.

McDonnell WJ, Koethe JR, Mallal SA, Pilkinton MA, Kirabo A, Ameka MK, Cottam MA, Hasty AH, Kennedy AJ.

Diabetes. 2018 Nov;67(11):2361-2376. doi: 10.2337/db18-0040. Epub 2018 Sep 4.

7.

Contributions of innate type 2 inflammation to adipose function.

Bolus WR, Hasty AH.

J Lipid Res. 2019 Oct;60(10):1698-1709. doi: 10.1194/jlr.R085993. Epub 2018 Jun 11. Review.

PMID:
29891508
8.

Links between Immunologic Memory and Metabolic Cycling.

Cottam MA, Itani HA, Beasley AA 4th, Hasty AH.

J Immunol. 2018 Jun 1;200(11):3681-3689. doi: 10.4049/jimmunol.1701713. Review.

9.

MFehi adipose tissue macrophages compensate for tissue iron perturbations in mice.

Hubler MJ, Erikson KM, Kennedy AJ, Hasty AH.

Am J Physiol Cell Physiol. 2018 Sep 1;315(3):C319-C329. doi: 10.1152/ajpcell.00103.2018. Epub 2018 May 16.

10.

Macrophage-Targeted Therapeutics for Metabolic Disease.

Peterson KR, Cottam MA, Kennedy AJ, Hasty AH.

Trends Pharmacol Sci. 2018 Jun;39(6):536-546. doi: 10.1016/j.tips.2018.03.001. Epub 2018 Apr 5. Review.

11.

Elevating adipose eosinophils in obese mice to physiologically normal levels does not rescue metabolic impairments.

Bolus WR, Peterson KR, Hubler MJ, Kennedy AJ, Gruen ML, Hasty AH.

Mol Metab. 2018 Feb;8:86-95. doi: 10.1016/j.molmet.2017.12.004. Epub 2017 Dec 16.

12.

Obesity Alters B Cell and Macrophage Populations in Brown Adipose Tissue.

Peterson KR, Flaherty DK, Hasty AH.

Obesity (Silver Spring). 2017 Nov;25(11):1881-1884. doi: 10.1002/oby.21982. Epub 2017 Sep 18.

13.

CC-chemokine receptor 7 (CCR7) deficiency alters adipose tissue leukocyte populations in mice.

Orr JS, Kennedy AJ, Hill AA, Anderson-Baucum EK, Hubler MJ, Hasty AH.

Physiol Rep. 2016 Sep;4(18). pii: e12971.

14.

Fat-water MRI of a diet-induced obesity mouse model at 15.2T.

Ong HH, Webb CD, Gruen ML, Hasty AH, Gore JC, Welch EB.

J Med Imaging (Bellingham). 2016 Apr;3(2):026002. doi: 10.1117/1.JMI.3.2.026002. Epub 2016 May 24.

15.

Activation of NF-κB drives the enhanced survival of adipose tissue macrophages in an obesogenic environment.

Hill AA, Anderson-Baucum EK, Kennedy AJ, Webb CD, Yull FE, Hasty AH.

Mol Metab. 2015 Jul 28;4(10):665-77. doi: 10.1016/j.molmet.2015.07.005. eCollection 2015 Oct.

16.

Macrophages are essential for CTGF-mediated adult β-cell proliferation after injury.

Riley KG, Pasek RC, Maulis MF, Dunn JC, Bolus WR, Kendall PL, Hasty AH, Gannon M.

Mol Metab. 2015 May 19;4(8):584-91. doi: 10.1016/j.molmet.2015.05.002. eCollection 2015 Aug.

17.

Retention of sedentary obese visceral white adipose tissue phenotype with intermittent physical activity despite reduced adiposity.

Wainright KS, Fleming NJ, Rowles JL, Welly RJ, Zidon TM, Park YM, Gaines TL, Scroggins RJ, Anderson-Baucum EK, Hasty AH, Vieira-Potter VJ, Padilla J.

Am J Physiol Regul Integr Comp Physiol. 2015 Sep;309(5):R594-602. doi: 10.1152/ajpregu.00042.2015. Epub 2015 Jul 15.

18.

CCR2 deficiency leads to increased eosinophils, alternative macrophage activation, and type 2 cytokine expression in adipose tissue.

Bolus WR, Gutierrez DA, Kennedy AJ, Anderson-Baucum EK, Hasty AH.

J Leukoc Biol. 2015 Oct;98(4):467-77. doi: 10.1189/jlb.3HI0115-018R. Epub 2015 May 1.

19.

Iron homeostasis: a new job for macrophages in adipose tissue?

Hubler MJ, Peterson KR, Hasty AH.

Trends Endocrinol Metab. 2015 Feb;26(2):101-9. doi: 10.1016/j.tem.2014.12.005. Epub 2015 Jan 16. Review.

20.

A decade of progress in adipose tissue macrophage biology.

Hill AA, Reid Bolus W, Hasty AH.

Immunol Rev. 2014 Nov;262(1):134-52. doi: 10.1111/imr.12216. Review.

21.

Striatal dopamine homeostasis is altered in mice following Roux-en-Y gastric bypass surgery.

Reddy IA, Wasserman DH, Ayala JE, Hasty AH, Abumrad NN, Galli A.

ACS Chem Neurosci. 2014 Oct 15;5(10):943-51. doi: 10.1021/cn500137d. Epub 2014 Aug 5.

22.

Regulation of S100B in white adipose tissue by obesity in mice.

Buckman LB, Anderson-Baucum EK, Hasty AH, Ellacott KLj.

Adipocyte. 2014 Jul 1;3(3):215-20. doi: 10.4161/adip.28730. Epub 2014 Apr 4.

23.

A possible secondary immune response in adipose tissue during weight cycling: The ups and downs of yo-yo dieting.

Anderson-Baucum EK, Major AS, Hasty AH.

Adipocyte. 2014 Apr 1;3(2):141-5. doi: 10.4161/adip.27556. Epub 2014 Jan 8.

24.

What have we really learned about macrophage recruitment to adipose tissue?

Hasty AH, Gutierrez DA.

Endocrinology. 2014 Jan;155(1):12-4. doi: 10.1210/en.2013-2027. No abstract available.

25.

Liver X receptor α-dependent iron handling in M2 macrophages: The missing link between cholesterol and intraplaque hemorrhage?

Hasty AH, Yvan-Charvet L.

Circ Res. 2013 Nov 8;113(11):1182-5. doi: 10.1161/CIRCRESAHA.113.302613. No abstract available.

PMID:
24201110
26.

Obesity alters adipose tissue macrophage iron content and tissue iron distribution.

Orr JS, Kennedy A, Anderson-Baucum EK, Webb CD, Fordahl SC, Erikson KM, Zhang Y, Etzerodt A, Moestrup SK, Hasty AH.

Diabetes. 2014 Feb;63(2):421-32. doi: 10.2337/db13-0213. Epub 2013 Oct 15.

27.

Loss of CCR5 results in glucose intolerance in diet-induced obese mice.

Kennedy A, Webb CD, Hill AA, Gruen ML, Jackson LG, Hasty AH.

Am J Physiol Endocrinol Metab. 2013 Oct 1;305(7):E897-906. doi: 10.1152/ajpendo.00177.2013. Epub 2013 Aug 13.

28.

Obesity induced by a high-fat diet is associated with increased immune cell entry into the central nervous system.

Buckman LB, Hasty AH, Flaherty DK, Buckman CT, Thompson MM, Matlock BK, Weller K, Ellacott KL.

Brain Behav Immun. 2014 Jan;35:33-42. doi: 10.1016/j.bbi.2013.06.007. Epub 2013 Jul 4.

29.

Weight cycling increases T-cell accumulation in adipose tissue and impairs systemic glucose tolerance.

Anderson EK, Gutierrez DA, Kennedy A, Hasty AH.

Diabetes. 2013 Sep;62(9):3180-8. doi: 10.2337/db12-1076. Epub 2013 Jun 3.

30.

Isolation of adipose tissue immune cells.

Orr JS, Kennedy AJ, Hasty AH.

J Vis Exp. 2013 May 22;(75):e50707. doi: 10.3791/50707.

31.

Hyaluronan accumulates with high-fat feeding and contributes to insulin resistance.

Kang L, Lantier L, Kennedy A, Bonner JS, Mayes WH, Bracy DP, Bookbinder LH, Hasty AH, Thompson CB, Wasserman DH.

Diabetes. 2013 Jun;62(6):1888-96. doi: 10.2337/db12-1502. Epub 2013 Jan 24.

32.

Endoplasmic reticulum stress and hypertension - a new paradigm?

Hasty AH, Harrison DG.

J Clin Invest. 2012 Nov;122(11):3859-61. doi: 10.1172/JCI65173. Epub 2012 Oct 15.

33.

Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages.

Orr JS, Puglisi MJ, Ellacott KL, Lumeng CN, Wasserman DH, Hasty AH.

Diabetes. 2012 Nov;61(11):2718-27. doi: 10.2337/db11-1595. Epub 2012 Jun 29.

34.

Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.

Anderson EK, Hill AA, Hasty AH.

Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1687-95. doi: 10.1161/ATVBAHA.112.250142. Epub 2012 May 3.

35.

Impact of macrophage inflammatory protein-1α deficiency on atherosclerotic lesion formation, hepatic steatosis, and adipose tissue expansion.

Kennedy A, Gruen ML, Gutierrez DA, Surmi BK, Orr JS, Webb CD, Hasty AH.

PLoS One. 2012;7(2):e31508. doi: 10.1371/journal.pone.0031508. Epub 2012 Feb 16.

36.

Haematopoietic leptin receptor deficiency does not affect macrophage accumulation in adipose tissue or systemic insulin sensitivity.

Gutierrez DA, Hasty AH.

J Endocrinol. 2012 Mar;212(3):343-51. doi: 10.1530/JOE-11-0338. Epub 2011 Dec 22.

37.

Aberrant accumulation of undifferentiated myeloid cells in the adipose tissue of CCR2-deficient mice delays improvements in insulin sensitivity.

Gutierrez DA, Kennedy A, Orr JS, Anderson EK, Webb CD, Gerrald WK, Hasty AH.

Diabetes. 2011 Nov;60(11):2820-9. doi: 10.2337/db11-0314. Epub 2011 Sep 16. Erratum in: Diabetes. 2012 May;61(5):1302-4.

38.

The role of adipose tissue in mediating the beneficial effects of dietary fish oil.

Puglisi MJ, Hasty AH, Saraswathi V.

J Nutr Biochem. 2011 Feb;22(2):101-8. doi: 10.1016/j.jnutbio.2010.07.003. Epub 2010 Dec 9. Review.

39.

Absence of macrophage inflammatory protein-1{alpha} does not impact macrophage accumulation in adipose tissue of diet-induced obese mice.

Surmi BK, Webb CD, Ristau AC, Hasty AH.

Am J Physiol Endocrinol Metab. 2010 Sep;299(3):E437-45. doi: 10.1152/ajpendo.00050.2010. Epub 2010 Jun 15.

40.

Adipose tissue recruitment of leukocytes.

Anderson EK, Gutierrez DA, Hasty AH.

Curr Opin Lipidol. 2010 Jun;21(3):172-7. doi: 10.1097/MOL.0b013e3283393867. Review.

41.

Mouse models of the metabolic syndrome.

Kennedy AJ, Ellacott KL, King VL, Hasty AH.

Dis Model Mech. 2010 Mar-Apr;3(3-4):156-66. doi: 10.1242/dmm.003467. Review.

42.

Nitro-fatty acids reduce atherosclerosis in apolipoprotein E-deficient mice.

Rudolph TK, Rudolph V, Edreira MM, Cole MP, Bonacci G, Schopfer FJ, Woodcock SR, Franek A, Pekarova M, Khoo NK, Hasty AH, Baldus S, Freeman BA.

Arterioscler Thromb Vasc Biol. 2010 May;30(5):938-45. doi: 10.1161/ATVBAHA.109.201582. Epub 2010 Feb 18.

43.

The role of chemokines in recruitment of immune cells to the artery wall and adipose tissue.

Surmi BK, Hasty AH.

Vascul Pharmacol. 2010 Jan-Feb;52(1-2):27-36. doi: 10.1016/j.vph.2009.12.004. Epub 2009 Dec 21. Review.

44.

Dietary fish oil exerts hypolipidemic effects in lean and insulin sensitizing effects in obese LDLR-/- mice.

Saraswathi V, Morrow JD, Hasty AH.

J Nutr. 2009 Dec;139(12):2380-6. doi: 10.3945/jn.109.111567. Epub 2009 Oct 28.

45.

Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet.

Li S, Sun Y, Liang CP, Thorp EB, Han S, Jehle AW, Saraswathi V, Pridgen B, Kanter JE, Li R, Welch CL, Hasty AH, Bornfeldt KE, Breslow JL, Tabas I, Tall AR.

Circ Res. 2009 Nov 20;105(11):1072-82. doi: 10.1161/CIRCRESAHA.109.199570. Epub 2009 Oct 15.

46.

Inhibition of long-chain acyl coenzyme A synthetases during fatty acid loading induces lipotoxicity in macrophages.

Saraswathi V, Hasty AH.

Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1937-43. doi: 10.1161/ATVBAHA.109.195362. Epub 2009 Aug 13.

47.

Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome.

Romero-Aleshire MJ, Diamond-Stanic MK, Hasty AH, Hoyer PB, Brooks HL.

Am J Physiol Regul Integr Comp Physiol. 2009 Sep;297(3):R587-92. doi: 10.1152/ajpregu.90762.2008. Epub 2009 May 13.

48.

Impact of increased adipose tissue mass on inflammation, insulin resistance, and dyslipidemia.

Gutierrez DA, Puglisi MJ, Hasty AH.

Curr Diab Rep. 2009 Feb;9(1):26-32.

49.

Impact of macrophage toll-like receptor 4 deficiency on macrophage infiltration into adipose tissue and the artery wall in mice.

Coenen KR, Gruen ML, Lee-Young RS, Puglisi MJ, Wasserman DH, Hasty AH.

Diabetologia. 2009 Feb;52(2):318-28. doi: 10.1007/s00125-008-1221-7. Epub 2008 Dec 4.

50.

Lipid and phospholipid profiling of biological samples using MALDI Fourier transform mass spectrometry.

Batoy SM, Borgmann S, Flick K, Griffith J, Jones JJ, Saraswathi V, Hasty AH, Kaiser P, Wilkins CL.

Lipids. 2009 Apr;44(4):367-71. doi: 10.1007/s11745-008-3260-8. Epub 2008 Nov 13.

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