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Items: 13

1.

High GILT Expression and an Active and Intact MHC Class II Antigen Presentation Pathway Are Associated with Improved Survival in Melanoma.

Buetow KH, Meador LR, Menon H, Lu YK, Brill J, Cui H, Roe DJ, DiCaudo DJ, Hastings KT.

J Immunol. 2019 Nov 15;203(10):2577-2587. doi: 10.4049/jimmunol.1900476. Epub 2019 Oct 7.

PMID:
31591149
2.

Immune Checkpoint Inhibitors in the Treatment of Melanoma: From Basic Science to Clinical Application.

Rausch MP, Hastings KT.

In: Ward WH, Farma JM, editors. Cutaneous Melanoma: Etiology and Therapy [Internet]. Brisbane (AU): Codon Publications; 2017 Dec 21. Chapter 9.

3.

Nab2 maintains thymus cellularity with aging and stress.

Hastings KT, Elizalde D, Muppana L, Levine S, Kamel CM, Ingram WM, Kirkpatrick JT, Hu C, Rausch MP, Gallitano AL.

Mol Immunol. 2017 May;85:185-195. doi: 10.1016/j.molimm.2017.02.019. Epub 2017 Mar 8.

4.

Gamma-interferon-inducible lysosomal thiol reductase is upregulated in human melanoma.

Nguyen J, Bernert R, In K, Kang P, Sebastiao N, Hu C, Hastings KT.

Melanoma Res. 2016 Apr;26(2):125-37. doi: 10.1097/CMR.0000000000000230.

5.

Diverse cellular and organismal functions of the lysosomal thiol reductase GILT.

Rausch MP, Hastings KT.

Mol Immunol. 2015 Dec;68(2 Pt A):124-8. doi: 10.1016/j.molimm.2015.06.008. Epub 2015 Jun 23. Review.

6.

An exhaustion-like phenotype constrains the activity of CD4+ T cells specific for a self and melanoma antigen.

Rausch MP, Hastings KT.

PLoS One. 2015 Apr 15;10(4):e0123332. doi: 10.1371/journal.pone.0123332. eCollection 2015.

7.

GILT: Shaping the MHC Class II-Restricted Peptidome and CD4(+) T Cell-Mediated Immunity.

Hastings KT.

Front Immunol. 2013 Dec 4;4:429. doi: 10.3389/fimmu.2013.00429. Review.

8.

Low GILT Expression is Associated with Poor Patient Survival in Diffuse Large B-Cell Lymphoma.

Phipps-Yonas H, Cui H, Sebastiao N, Brunhoeber PS, Haddock E, Deymier MJ, Klapper W, Lybarger L, Roe DJ, Hastings KT.

Front Immunol. 2013 Dec 4;4:425. doi: 10.3389/fimmu.2013.00425. eCollection 2013.

9.

GILT expression in B cells diminishes cathepsin S steady-state protein expression and activity.

Phipps-Yonas H, Semik V, Hastings KT.

Eur J Immunol. 2013 Jan;43(1):65-74. doi: 10.1002/eji.201242379. Epub 2012 Nov 26.

10.

GILT modulates CD4+ T-cell tolerance to the melanocyte differentiation antigen tyrosinase-related protein 1.

Rausch MP, Hastings KT.

J Invest Dermatol. 2012 Jan;132(1):154-62. doi: 10.1038/jid.2011.236. Epub 2011 Aug 11.

11.

Disulfide reduction in the endocytic pathway: immunological functions of gamma-interferon-inducible lysosomal thiol reductase.

Hastings KT, Cresswell P.

Antioxid Redox Signal. 2011 Aug 1;15(3):657-68. doi: 10.1089/ars.2010.3684. Epub 2011 Apr 20. Review.

12.

GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1.

Rausch MP, Irvine KR, Antony PA, Restifo NP, Cresswell P, Hastings KT.

J Immunol. 2010 Sep 1;185(5):2828-35. doi: 10.4049/jimmunol.1000945. Epub 2010 Jul 28.

13.

Functional requirements for the lysosomal thiol reductase GILT in MHC class II-restricted antigen processing.

Hastings KT, Lackman RL, Cresswell P.

J Immunol. 2006 Dec 15;177(12):8569-77.

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