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Items: 25


AgBR1 antibodies delay lethal Aedes aegypti-borne West Nile virus infection in mice.

Uraki R, Hastings AK, Brackney DE, Armstrong PM, Fikrig E.

NPJ Vaccines. 2019 Jul 8;4:23. doi: 10.1038/s41541-019-0120-x. eCollection 2019.


Aedes aegypti NeSt1 Protein Enhances Zika Virus Pathogenesis by Activating Neutrophils.

Hastings AK, Uraki R, Gaitsch H, Dhaliwal K, Stanley S, Sproch H, Williamson E, MacNeil T, Marin-Lopez A, Hwang J, Wang Y, Grover JR, Fikrig E.

J Virol. 2019 Jun 14;93(13). pii: e00395-19. doi: 10.1128/JVI.00395-19. Print 2019 Jul 1.


Loss of the TAM Receptor Axl Ameliorates Severe Zika Virus Pathogenesis and Reduces Apoptosis in Microglia.

Hastings AK, Hastings K, Uraki R, Hwang J, Gaitsch H, Dhaliwal K, Williamson E, Fikrig E.

iScience. 2019 Mar 29;13:339-350. doi: 10.1016/j.isci.2019.03.003. Epub 2019 Mar 5.


Aedes aegypti AgBR1 antibodies modulate early Zika virus infection of mice.

Uraki R, Hastings AK, Marin-Lopez A, Sumida T, Takahashi T, Grover JR, Iwasaki A, Hafler DA, Montgomery RR, Fikrig E.

Nat Microbiol. 2019 Jun;4(6):948-955. doi: 10.1038/s41564-019-0385-x. Epub 2019 Mar 11.


Daily oscillations in expression and responsiveness of Toll-like receptors in splenic immune cells.

Silver AC, Buckley SM, Hughes ME, Hastings AK, Nitabach MN, Fikrig E.

Heliyon. 2018 Mar 20;4(3):e00579. doi: 10.1016/j.heliyon.2018.e00579. eCollection 2018 Mar.


Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice.

Dragovic SM, Agunbiade TA, Freudzon M, Yang J, Hastings AK, Schleicher TR, Zhou X, Craft S, Chuang YM, Gonzalez F, Li Y, Hrebikova G, Tripathi A, Mlambo G, Almeras L, Ploss A, Dimopoulos G, Fikrig E.

Cell Host Microbe. 2018 Apr 11;23(4):523-535.e5. doi: 10.1016/j.chom.2018.03.008.


Altered vector competence in an experimental mosquito-mouse transmission model of Zika infection.

Uraki R, Hastings AK, Gloria-Soria A, Powell JR, Fikrig E.

PLoS Negl Trop Dis. 2018 Mar 5;12(3):e0006350. doi: 10.1371/journal.pntd.0006350. eCollection 2018 Mar.


Type I interferons instigate fetal demise after Zika virus infection.

Yockey LJ, Jurado KA, Arora N, Millet A, Rakib T, Milano KM, Hastings AK, Fikrig E, Kong Y, Horvath TL, Weatherbee S, Kliman HJ, Coyne CB, Iwasaki A.

Sci Immunol. 2018 Jan 5;3(19). pii: eaao1680. doi: 10.1126/sciimmunol.aao1680.


Complete Genome Sequence and Comparative Analysis of Staphylococcus condimenti DSM 11674, a Potential Starter Culture Isolated from Soy Sauce Mash.

Dong H, Chen J, Hastings AK, Guo L, Zheng B.

Front Bioeng Biotechnol. 2017 Oct 6;5:56. doi: 10.3389/fbioe.2017.00056. eCollection 2017. No abstract available.


Zika Virus and Sexual Transmission: A New Route of Transmission for Mosquito-borne Flaviviruses

Hastings AK, Fikrig E.

Yale J Biol Med. 2017 Jun 23;90(2):325-330. eCollection 2017 Jun. Review.


TAM Receptors Are Not Required for Zika Virus Infection in Mice.

Hastings AK, Yockey LJ, Jagger BW, Hwang J, Uraki R, Gaitsch HF, Parnell LA, Cao B, Mysorekar IU, Rothlin CV, Fikrig E, Diamond MS, Iwasaki A.

Cell Rep. 2017 Apr 18;19(3):558-568. doi: 10.1016/j.celrep.2017.03.058.


Zika virus causes testicular atrophy.

Uraki R, Hwang J, Jurado KA, Householder S, Yockey LJ, Hastings AK, Homer RJ, Iwasaki A, Fikrig E.

Sci Adv. 2017 Feb 22;3(2):e1602899. doi: 10.1126/sciadv.1602899. eCollection 2017 Feb.


Tropical ancient DNA reveals relationships of the extinct Bahamian giant tortoise Chelonoidis alburyorum.

Kehlmaier C, Barlow A, Hastings AK, Vamberger M, Paijmans JL, Steadman DW, Albury NA, Franz R, Hofreiter M, Fritz U.

Proc Biol Sci. 2017 Jan 11;284(1846). pii: 20162235. doi: 10.1098/rspb.2016.2235.


Human metapneumovirus small hydrophobic (SH) protein downregulates type I IFN pathway signaling by affecting STAT1 expression and phosphorylation.

Hastings AK, Amato KR, Wen SC, Peterson LS, Williams JV.

Virology. 2016 Jul;494:248-56. doi: 10.1016/j.virol.2016.04.022. Epub 2016 Apr 27.


Novel HLA-A2-restricted human metapneumovirus epitopes reduce viral titers in mice and are recognized by human T cells.

Hastings AK, Gilchuk P, Joyce S, Williams JV.

Vaccine. 2016 May 23;34(24):2663-70. doi: 10.1016/j.vaccine.2016.04.034. Epub 2016 Apr 19.


EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer.

Amato KR, Wang S, Tan L, Hastings AK, Song W, Lovly CM, Meador CB, Ye F, Lu P, Balko JM, Colvin DC, Cates JM, Pao W, Gray NS, Chen J.

Cancer Res. 2016 Jan 15;76(2):305-18. doi: 10.1158/0008-5472.CAN-15-0717. Epub 2016 Jan 7.


Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes.

Cox RG, Mainou BA, Johnson M, Hastings AK, Schuster JE, Dermody TS, Williams JV.

PLoS Pathog. 2015 Dec 2;11(12):e1005303. doi: 10.1371/journal.ppat.1005303. eCollection 2015 Dec.


Acute Viral Respiratory Infection Rapidly Induces a CD8+ T Cell Exhaustion-like Phenotype.

Erickson JJ, Lu P, Wen S, Hastings AK, Gilchuk P, Joyce S, Shyr Y, Williams JV.

J Immunol. 2015 Nov 1;195(9):4319-30. doi: 10.4049/jimmunol.1403004. Epub 2015 Sep 23.


Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication.

Hastings AK, Erickson JJ, Schuster JE, Boyd KL, Tollefson SJ, Johnson M, Gilchuk P, Joyce S, Williams JV.

J Virol. 2015 Apr;89(8):4405-20. doi: 10.1128/JVI.03275-14. Epub 2015 Feb 4.


Programmed death-1 impairs secondary effector lung CD8⁺ T cells during respiratory virus reinfection.

Erickson JJ, Rogers MC, Hastings AK, Tollefson SJ, Williams JV.

J Immunol. 2014 Nov 15;193(10):5108-17. doi: 10.4049/jimmunol.1302208. Epub 2014 Oct 22.


A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus.

Schuster JE, Cox RG, Hastings AK, Boyd KL, Wadia J, Chen Z, Burton DR, Williamson RA, Williams JV.

J Infect Dis. 2015 Jan 15;211(2):216-25. doi: 10.1093/infdis/jiu307. Epub 2014 May 26.


Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC.

Amato KR, Wang S, Hastings AK, Youngblood VM, Santapuram PR, Chen H, Cates JM, Colvin DC, Ye F, Brantley-Sieders DM, Cook RS, Tan L, Gray NS, Chen J.

J Clin Invest. 2014 May;124(5):2037-49. doi: 10.1172/JCI72522. Epub 2014 Apr 8.


Human metapneumovirus virus-like particles induce protective B and T cell responses in a mouse model.

Cox RG, Erickson JJ, Hastings AK, Becker JC, Johnson M, Craven RE, Tollefson SJ, Boyd KL, Williams JV.

J Virol. 2014 Jun;88(11):6368-79. doi: 10.1128/JVI.00332-14. Epub 2014 Mar 26.


Viral acute lower respiratory infections impair CD8+ T cells through PD-1.

Erickson JJ, Gilchuk P, Hastings AK, Tollefson SJ, Johnson M, Downing MB, Boyd KL, Johnson JE, Kim AS, Joyce S, Williams JV.

J Clin Invest. 2012 Aug;122(8):2967-82. doi: 10.1172/JCI62860. Epub 2012 Jul 17.


Giant boid snake from the Palaeocene neotropics reveals hotter past equatorial temperatures.

Head JJ, Bloch JI, Hastings AK, Bourque JR, Cadena EA, Herrera FA, Polly PD, Jaramillo CA.

Nature. 2009 Feb 5;457(7230):715-7. doi: 10.1038/nature07671. Erratum in: Nature. 2011 Jul 28;475(7357):532.


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