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Items: 1 to 50 of 81

1.

Temporal changes in chromosome abnormalities in human spontaneous abortions: Results of 40 years of analysis.

Hardy K, Hardy PJ, Jacobs PA, Lewallen K, Hassold TJ.

Am J Med Genet A. 2016 Oct;170(10):2671-80. doi: 10.1002/ajmg.a.37795. Epub 2016 Jun 10.

PMID:
27287007
2.

Estrogenic exposure alters the spermatogonial stem cells in the developing testis, permanently reducing crossover levels in the adult.

Vrooman LA, Oatley JM, Griswold JE, Hassold TJ, Hunt PA.

PLoS Genet. 2015 Jan 23;11(1):e1004949. doi: 10.1371/journal.pgen.1004949. eCollection 2015 Jan.

3.

Evidence for paternal age-related alterations in meiotic chromosome dynamics in the mouse.

Vrooman LA, Nagaoka SI, Hassold TJ, Hunt PA.

Genetics. 2014 Feb;196(2):385-96. doi: 10.1534/genetics.113.158782. Epub 2013 Dec 6.

4.

Human aneuploidy: mechanisms and new insights into an age-old problem.

Nagaoka SI, Hassold TJ, Hunt PA.

Nat Rev Genet. 2012 Jun 18;13(7):493-504. doi: 10.1038/nrg3245. Review.

5.

An algorithm for determining the origin of trisomy and the positions of chiasmata from SNP genotype data.

Gabriel AS, Hassold TJ, Thornhill AR, Affara NA, Handyside AH, Griffin DK.

Chromosome Res. 2011 Feb;19(2):155-63. doi: 10.1007/s10577-010-9181-4. Epub 2011 Jan 12.

PMID:
21225334
6.

Predicting meiotic pathways in human fetal oogenesis.

Zheng P, Griswold MD, Hassold TJ, Hunt PA, Small CL, Ye P.

Biol Reprod. 2010 Mar;82(3):543-51. doi: 10.1095/biolreprod.109.079590. Epub 2009 Oct 21.

7.

Meiotic recombination in human oocytes.

Cheng EY, Hunt PA, Naluai-Cecchini TA, Fligner CL, Fujimoto VY, Pasternack TL, Schwartz JM, Steinauer JE, Woodruff TJ, Cherry SM, Hansen TA, Vallente RU, Broman KW, Hassold TJ.

PLoS Genet. 2009 Sep;5(9):e1000661. doi: 10.1371/journal.pgen.1000661. Epub 2009 Sep 18.

8.

The bisphenol A experience: a primer for the analysis of environmental effects on mammalian reproduction.

Hunt PA, Susiarjo M, Rubio C, Hassold TJ.

Biol Reprod. 2009 Nov;81(5):807-13. doi: 10.1095/biolreprod.109.077008. Epub 2009 May 20. Review.

9.

Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice.

Anderson EL, Baltus AE, Roepers-Gajadien HL, Hassold TJ, de Rooij DG, van Pelt AM, Page DC.

Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14976-80. doi: 10.1073/pnas.0807297105. Epub 2008 Sep 17.

10.

Proteins involved in meiotic recombination: a role in male infertility?

Sanderson ML, Hassold TJ, Carrell DT.

Syst Biol Reprod Med. 2008 Mar-Apr;54(2):57-74. doi: 10.1080/19396360701881922. Review.

PMID:
18446647
11.

Human female meiosis: what makes a good egg go bad?

Hunt PA, Hassold TJ.

Trends Genet. 2008 Feb;24(2):86-93. doi: 10.1016/j.tig.2007.11.010. Epub 2008 Jan 14. Review.

PMID:
18192063
12.

The origin of trisomy 13.

Hall HE, Chan ER, Collins A, Judis L, Shirley S, Surti U, Hoffner L, Cockwell AE, Jacobs PA, Hassold TJ.

Am J Med Genet A. 2007 Oct 1;143A(19):2242-8.

PMID:
17853475
13.

The Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosis.

Cherry SM, Adelman CA, Theunissen JW, Hassold TJ, Hunt PA, Petrini JH.

Curr Biol. 2007 Feb 20;17(4):373-8. Epub 2007 Feb 8.

14.

Bisphenol A exposure in utero disrupts early oogenesis in the mouse.

Susiarjo M, Hassold TJ, Freeman E, Hunt PA.

PLoS Genet. 2007 Jan 12;3(1):e5.

15.

Near-human aneuploidy levels in female mice with homeologous chromosomes.

Koehler KE, Schrump SE, Cherry JP, Hassold TJ, Hunt PA.

Curr Biol. 2006 Aug 8;16(15):R579-80. No abstract available.

16.

The synaptonemal complex and meiotic recombination in humans: new approaches to old questions.

Vallente RU, Cheng EY, Hassold TJ.

Chromosoma. 2006 Jun;115(3):241-9. Epub 2006 Mar 18. Review.

PMID:
16547726
17.

SMC1beta-deficient female mice provide evidence that cohesins are a missing link in age-related nondisjunction.

Hodges CA, Revenkova E, Jessberger R, Hassold TJ, Hunt PA.

Nat Genet. 2005 Dec;37(12):1351-5. Epub 2005 Oct 30.

PMID:
16258540
18.

Effect of meiotic recombination on the production of aneuploid gametes in humans.

Lamb NE, Sherman SL, Hassold TJ.

Cytogenet Genome Res. 2005;111(3-4):250-5. Review.

PMID:
16192701
19.

Meiotic synapsis proceeds from a limited number of subtelomeric sites in the human male.

Brown PW, Judis L, Chan ER, Schwartz S, Seftel A, Thomas A, Hassold TJ.

Am J Hum Genet. 2005 Oct;77(4):556-66. Epub 2005 Aug 16.

20.

Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome.

Mann MB, Hodges CA, Barnes E, Vogel H, Hassold TJ, Luo G.

Hum Mol Genet. 2005 Mar 15;14(6):813-25. Epub 2005 Feb 9.

PMID:
15703196
21.

Nondisjunction--a view from ringside.

Lamb NE, Hassold TJ.

N Engl J Med. 2004 Nov 4;351(19):1931-4. No abstract available.

PMID:
15525719
22.

Cisplatin disrupts mammalian spermatogenesis, but does not affect recombination or chromosome segregation.

Cherry SM, Hunt PA, Hassold TJ.

Mutat Res. 2004 Dec 12;564(2):115-28.

PMID:
15507376
23.

Meiotic exchange and segregation in female mice heterozygous for paracentric inversions.

Koehler KE, Millie EA, Cherry JP, Schrump SE, Hassold TJ.

Genetics. 2004 Mar;166(3):1199-214.

24.

Aberrant recombination and the origin of Klinefelter syndrome.

Thomas NS, Hassold TJ.

Hum Reprod Update. 2003 Jul-Aug;9(4):309-17. Review.

PMID:
12926525
25.

Bisphenol a exposure causes meiotic aneuploidy in the female mouse.

Hunt PA, Koehler KE, Susiarjo M, Hodges CA, Ilagan A, Voigt RC, Thomas S, Thomas BF, Hassold TJ.

Curr Biol. 2003 Apr 1;13(7):546-53.

26.

Sex-specific differences in meiotic chromosome segregation revealed by dicentric bridge resolution in mice.

Koehler KE, Millie EA, Cherry JP, Burgoyne PS, Evans EP, Hunt PA, Hassold TJ.

Genetics. 2002 Nov;162(3):1367-79.

27.
28.

Fertilization in vitro increases non-disjunction during early cleavage divisions in a mouse model system.

Bean CJ, Hassold TJ, Judis L, Hunt PA.

Hum Reprod. 2002 Sep;17(9):2362-7.

PMID:
12202426
29.

Sex matters in meiosis.

Hunt PA, Hassold TJ.

Science. 2002 Jun 21;296(5576):2181-3. Review.

PMID:
12077403
30.

Covariation of synaptonemal complex length and mammalian meiotic exchange rates.

Lynn A, Koehler KE, Judis L, Chan ER, Cherry JP, Schwartz S, Seftel A, Hunt PA, Hassold TJ.

Science. 2002 Jun 21;296(5576):2222-5. Epub 2002 Jun 6.

31.

Maternal folate polymorphisms and the etiology of human nondisjunction.

Hassold TJ, Burrage LC, Chan ER, Judis LM, Schwartz S, James SJ, Jacobs PA, Thomas NS.

Am J Hum Genet. 2001 Aug;69(2):434-9. Epub 2001 Jul 5.

32.

Risk factors for trisomy 21: maternal cigarette smoking and oral contraceptive use in a population-based case-control study.

Yang Q, Sherman SL, Hassold TJ, Allran K, Taft L, Pettay D, Khoury MJ, Erickson JD, Freeman SB.

Genet Med. 1999 Mar-Apr;1(3):80-8.

PMID:
11336457
33.
34.

Maternal sex chromosome non-disjunction: evidence for X chromosome-specific risk factors.

Thomas NS, Ennis S, Sharp AJ, Durkie M, Hassold TJ, Collins AR, Jacobs PA.

Hum Mol Genet. 2001 Feb 1;10(3):243-50.

PMID:
11159943
35.

A reinvestigation of non-disjunction resulting in 47, XXY males of paternal origin.

Thomas NS, Collins AR, Hassold TJ, Jacobs PA.

Eur J Hum Genet. 2000 Oct;8(10):805-8.

36.

Cks1 mediates vascular smooth muscle cell polyploidization.

Hixon ML, Obejero-Paz C, Muro-Cacho C, Wagner MW, Millie E, Nagy J, Hassold TJ, Gualberto A.

J Biol Chem. 2000 Dec 22;275(51):40434-42.

37.

Rapid generation of nested chromosomal deletions on mouse chromosome 2.

LePage DF, Church DM, Millie E, Hassold TJ, Conlon RA.

Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10471-6.

38.

Somatic segregation errors predominantly contribute to the gain or loss of a paternal chromosome leading to uniparental disomy for chromosome 15.

Robinson WP, Christian SL, Kuchinka BD, PeƱaherrera MS, Das S, Schuffenhauer S, Malcolm S, Schinzel AA, Hassold TJ, Ledbetter DH.

Clin Genet. 2000 May;57(5):349-58.

PMID:
10852369
39.

Parental origin and phenotype of triploidy in spontaneous abortions: predominance of diandry and association with the partial hydatidiform mole.

Zaragoza MV, Surti U, Redline RW, Millie E, Chakravarti A, Hassold TJ.

Am J Hum Genet. 2000 Jun;66(6):1807-20. Epub 2000 May 5.

40.

Is disomic homozygosity at the APECED locus the cause of increased autoimmunity in Down's syndrome?

Shield JP, Wadsworth EJ, Hassold TJ, Judis LA, Jacobs PA.

Arch Dis Child. 1999 Aug;81(2):147-50.

41.

Sperm aneuploidy among Chinese pesticide factory workers: scoring by the FISH method.

Padungtod C, Hassold TJ, Millie E, Ryan LM, Savitz DA, Christiani DC, Xu X.

Am J Ind Med. 1999 Aug;36(2):230-8.

PMID:
10398931
42.

Human aneuploidy: lessons from achiasmate segregation in Drosophila melanogaster.

Koehler KE, Hassold TJ.

Ann Hum Genet. 1998 Nov;62(Pt 6):467-79. Review.

43.
44.

Population-based study of congenital heart defects in Down syndrome.

Freeman SB, Taft LF, Dooley KJ, Allran K, Sherman SL, Hassold TJ, Khoury MJ, Saker DM.

Am J Med Genet. 1998 Nov 16;80(3):213-7.

PMID:
9843040
45.
46.

Systematic search for uniparental disomy in early fetal losses: the results and a review of the literature.

Shaffer LG, McCaskill C, Adkins K, Hassold TJ.

Am J Med Genet. 1998 Oct 12;79(5):366-72. Review.

PMID:
9779803
47.

Elucidating the mechanisms of paternal non-disjunction of chromosome 21 in humans.

Savage AR, Petersen MB, Pettay D, Taft L, Allran K, Freeman SB, Karadima G, Avramopoulos D, Torfs C, Mikkelsen M, Hassold TJ, Sherman SL.

Hum Mol Genet. 1998 Aug;7(8):1221-7.

PMID:
9668162
48.

Centromeric genotyping and direct analysis of nondisjunction in humans: Down syndrome.

Shen JJ, Sherman SL, Hassold TJ.

Chromosoma. 1998 Jun;107(3):166-72.

PMID:
9639654
49.

Maternal meiosis I non-disjunction of chromosome 15: dependence of the maternal age effect on level of recombination.

Robinson WP, Kuchinka BD, Bernasconi F, Petersen MB, Schulze A, Brondum-Nielsen K, Christian SL, Ledbetter DH, Schinzel AA, Horsthemke B, Schuffenhauer S, Michaelis RC, Langlois S, Hassold TJ.

Hum Mol Genet. 1998 Jun;7(6):1011-9.

PMID:
9580665
50.

Alphoid variant-specific FISH probes can distinguish autosomal meiosis I from meiosis II non-disjunction in human sperm.

O'Keefe CL, Griffin DK, Bean CJ, Matera AG, Hassold TJ.

Hum Genet. 1997 Nov;101(1):61-6.

PMID:
9385371

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