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Items: 1 to 50 of 213

1.

SeeTB: A novel alternative to sputum smear microscopy to diagnose tuberculosis in high burden countries.

Pandey V, Singh P, Singh S, Arora N, Quadir N, Singh S, Das A, Dudeja M, Kapur P, Ehtesham NZ, Elangovan R, Hasnain SE.

Sci Rep. 2019 Nov 12;9(1):16371. doi: 10.1038/s41598-019-52739-9.

2.

Disorder-to-order transition in PE-PPE proteins of Mycobacterium tuberculosis augments the pro-pathogen immune response.

Ahmad J, Khubaib M, Sheikh JA, Pancsa R, Kumar S, Srinivasan A, Babu MM, Hasnain SE, Ehtesham NZ.

FEBS Open Bio. 2019 Oct 23. doi: 10.1002/2211-5463.12749. [Epub ahead of print]

3.

Medical implications of protein moonlighting.

Gupta MN, Pandey S, Ehtesham NZ, Hasnain SE.

Indian J Med Res. 2019 Mar;149(3):322-325. doi: 10.4103/ijmr.IJMR_2192_18. No abstract available.

4.

Forensic Epigenetic Analysis: The Path Ahead.

Sabeeha, Hasnain SE.

Med Princ Pract. 2019;28(4):301-308. doi: 10.1159/000499496. Epub 2019 Mar 12. Review.

5.

Peptidyl-prolyl isomerase-B is involved in Mycobacterium tuberculosis biofilm formation and a generic target for drug repurposing-based intervention.

Kumar A, Alam A, Grover S, Pandey S, Tripathi D, Kumari M, Rani M, Singh A, Akhter Y, Ehtesham NZ, Hasnain SE.

NPJ Biofilms Microbiomes. 2019 Jan 15;5:3. doi: 10.1038/s41522-018-0075-0. eCollection 2019.

6.

Mycobacterium indicus pranii protein MIP_05962 induces Th1 cell mediated immune response in mice.

Sharma A, Saqib M, Sheikh JA, Ehtesham NZ, Bhaskar S, Chaudhuri TK, Hasnain SE.

Int J Med Microbiol. 2018 Dec;308(8):1000-1008. doi: 10.1016/j.ijmm.2018.08.008. Epub 2018 Aug 29.

PMID:
30190103
7.

The PGRS Domain of Mycobacterium tuberculosis PE_PGRS Protein Rv0297 Is Involved in Endoplasmic Reticulum Stress-Mediated Apoptosis through Toll-Like Receptor 4.

Grover S, Sharma T, Singh Y, Kohli S, P M, Singh A, Semmler T, Wieler LH, Tedin K, Ehtesham NZ, Hasnain SE.

MBio. 2018 Jun 19;9(3). pii: e01017-18. doi: 10.1128/mBio.01017-18.

8.

Amino acid starvation sensing dampens IL-1β production by activating riboclustering and autophagy.

Battu S, Afroz S, Giddaluru J, Naz S, Huang W, Khumukcham SS, Khan RA, Bhat SY, Qureshi IA, Manavathi B, Khan AA, August A, Hasnain SE, Khan N.

PLoS Biol. 2018 Apr 5;16(4):e2005317. doi: 10.1371/journal.pbio.2005317. eCollection 2018 Apr.

9.

Contrasting Function of Structured N-Terminal and Unstructured C-Terminal Segments of Mycobacterium tuberculosis PPE37 Protein.

Ahmad J, Farhana A, Pancsa R, Arora SK, Srinivasan A, Tyagi AK, Babu MM, Ehtesham NZ, Hasnain SE.

MBio. 2018 Jan 23;9(1). pii: e01712-17. doi: 10.1128/mBio.01712-17.

10.

Protein adaptations in extremophiles: An insight into extremophilic connection of mycobacterial proteome.

Kumar A, Alam A, Tripathi D, Rani M, Khatoon H, Pandey S, Ehtesham NZ, Hasnain SE.

Semin Cell Dev Biol. 2018 Dec;84:147-157. doi: 10.1016/j.semcdb.2018.01.003. Epub 2018 Jan 17. Review.

PMID:
29331642
11.

Biofilms: Survival and defense strategy for pathogens.

Kumar A, Alam A, Rani M, Ehtesham NZ, Hasnain SE.

Int J Med Microbiol. 2017 Dec;307(8):481-489. doi: 10.1016/j.ijmm.2017.09.016. Epub 2017 Sep 21. Review.

PMID:
28950999
12.

Commentary: Modification of Host Responses by Mycobacteria.

Kumar A, Rani M, Ehtesham NZ, Hasnain SE.

Front Immunol. 2017 Apr 28;8:466. doi: 10.3389/fimmu.2017.00466. eCollection 2017. No abstract available.

13.

Immunodominant protein MIP_05962 from Mycobacterium indicus pranii displays chaperone activity.

Sharma A, Equbal MJ, Pandey S, Sheikh JA, Ehtesham NZ, Hasnain SE, Chaudhuri TK.

FEBS J. 2017 May;284(9):1338-1354. doi: 10.1111/febs.14057. Epub 2017 Apr 10.

14.

Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Are Immunogenic, Alter Cytokine Profile and Aid in Intracellular Survival.

Pandey S, Tripathi D, Khubaib M, Kumar A, Sheikh JA, Sumanlatha G, Ehtesham NZ, Hasnain SE.

Front Cell Infect Microbiol. 2017 Feb 15;7:38. doi: 10.3389/fcimb.2017.00038. eCollection 2017.

15.

Mycobacterium tuberculosis Co-operonic PE32/PPE65 Proteins Alter Host Immune Responses by Hampering Th1 Response.

Khubaib M, Sheikh JA, Pandey S, Srikanth B, Bhuwan M, Khan N, Hasnain SE, Ehtesham NZ.

Front Microbiol. 2016 May 17;7:719. doi: 10.3389/fmicb.2016.00719. eCollection 2016.

16.

Analyses of methyltransferases across the pathogenicity spectrum of different mycobacterial species point to an extremophile connection.

Grover S, Gupta P, Kahlon PS, Goyal S, Grover A, Dalal K, Sabeeha, Ehtesham NZ, Hasnain SE.

Mol Biosyst. 2016 May 26;12(5):1615-25. doi: 10.1039/c5mb00810g. Epub 2016 Mar 17.

PMID:
26983646
17.

Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Also Exhibit Chaperone like Activity In-Vitro and In-Vivo.

Pandey S, Sharma A, Tripathi D, Kumar A, Khubaib M, Bhuwan M, Chaudhuri TK, Hasnain SE, Ehtesham NZ.

PLoS One. 2016 Mar 16;11(3):e0150288. doi: 10.1371/journal.pone.0150288. eCollection 2016.

18.

Interaction of Mycobacterium tuberculosis Virulence Factor RipA with Chaperone MoxR1 Is Required for Transport through the TAT Secretion System.

Bhuwan M, Arora N, Sharma A, Khubaib M, Pandey S, Chaudhuri TK, Hasnain SE, Ehtesham NZ.

MBio. 2016 Mar 1;7(2):e02259. doi: 10.1128/mBio.02259-15.

19.

Orchestration of membrane receptor signaling by membrane lipids.

Arish M, Husein A, Kashif M, Sandhu P, Hasnain SE, Akhter Y, Rub A.

Biochimie. 2015 Jun;113:111-24. doi: 10.1016/j.biochi.2015.04.005. Epub 2015 Apr 16. Review.

PMID:
25890158
20.
21.
22.

Human mesenchymal stem cells: New sojourn of bacterial pathogens.

Kohli S, Singh Y, Sowpati DT, Ehtesham NZ, Dobrindt U, Hacker J, Hasnain SE.

Int J Med Microbiol. 2015 May;305(3):322-6. doi: 10.1016/j.ijmm.2015.01.001. Epub 2015 Jan 13. Review.

PMID:
25648374
23.

Whole genome sequencing: a new paradigm in the surveillance and control of human tuberculosis.

Hasnain SE, O'Toole RF, Grover S, Ehtesham NZ.

Tuberculosis (Edinb). 2015 Mar;95(2):91-4. doi: 10.1016/j.tube.2014.12.007. Epub 2014 Dec 31. Review.

PMID:
25586521
24.

Comparative genomic analysis of Helicobacter pylori from Malaysia identifies three distinct lineages suggestive of differential evolution.

Kumar N, Mariappan V, Baddam R, Lankapalli AK, Shaik S, Goh KL, Loke MF, Perkins T, Benghezal M, Hasnain SE, Vadivelu J, Marshall BJ, Ahmed N.

Nucleic Acids Res. 2015 Jan;43(1):324-35. doi: 10.1093/nar/gku1271. Epub 2014 Dec 1.

25.

Mycobacterium tuberculosis PE25/PPE41 protein complex induces necrosis in macrophages: Role in virulence and disease reactivation?

Tundup S, Mohareer K, Hasnain SE.

FEBS Open Bio. 2014 Sep 16;4:822-8. doi: 10.1016/j.fob.2014.09.001. eCollection 2014.

26.

Comparative analyses of nonpathogenic, opportunistic, and totally pathogenic mycobacteria reveal genomic and biochemical variabilities and highlight the survival attributes of Mycobacterium tuberculosis.

Rahman SA, Singh Y, Kohli S, Ahmad J, Ehtesham NZ, Tyagi AK, Hasnain SE.

MBio. 2014 Nov 4;5(6):e02020. doi: 10.1128/mBio.02020-14. Erratum in: MBio. 2015;6(1):e02343-14.

27.

Holobionts: emerging strategy for interventions against infectious diseases, metabolic disorders & cancer.

Singh Y, Hasnain SE.

Indian J Med Res. 2014 Jul;140(1):11-4. No abstract available.

28.

Gene cooption in mycobacteria and search for virulence attributes: comparative proteomic analyses of Mycobacterium tuberculosis, Mycobacterium indicus pranii and other mycobacteria.

Singh Y, Kohli S, Sowpati DT, Rahman SA, Tyagi AK, Hasnain SE.

Int J Med Microbiol. 2014 Jul;304(5-6):742-8. doi: 10.1016/j.ijmm.2014.05.006. Epub 2014 May 29.

PMID:
24951307
29.

Mycobacterium avium subsp. paratuberculosis is not discerned in diabetes mellitus patients in Hyderabad, India.

Rani PS, Doddam SN, Agrawal S, Hasnain SE, Sechi LA, Kumar A, Ahmed N.

Int J Med Microbiol. 2014 Jul;304(5-6):620-5. doi: 10.1016/j.ijmm.2014.04.010. Epub 2014 May 5.

PMID:
24863528
30.

A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages.

Alamuru NP, Behera S, Butchar JP, Tridandapani S, Kaimal Suraj S, Babu PP, Hasnain SE, Ehtesham NZ, Parsa KV.

J Leukoc Biol. 2014 May;95(5):775-783. Epub 2014 Jan 17.

PMID:
24443556
31.

Dormancy Associated Translation Inhibitor (DATIN/Rv0079) of Mycobacterium tuberculosis interacts with TLR2 and induces proinflammatory cytokine expression.

Kumar A, Lewin A, Rani PS, Qureshi IA, Devi S, Majid M, Kamal E, Marek S, Hasnain SE, Ahmed N.

Cytokine. 2013 Oct;64(1):258-64. doi: 10.1016/j.cyto.2013.06.310. Epub 2013 Jun 29.

PMID:
23819907
32.

MicroRNA in carcinogenesis & cancer diagnostics: a new paradigm.

Ahmad J, Hasnain SE, Siddiqui MA, Ahamed M, Musarrat J, Al-Khedhairy AA.

Indian J Med Res. 2013 Apr;137(4):680-94. Review.

33.

Emerging importance of holobionts in evolution and in probiotics.

Singh Y, Ahmad J, Musarrat J, Ehtesham NZ, Hasnain SE.

Gut Pathog. 2013 May 22;5(1):12. doi: 10.1186/1757-4749-5-12.

34.

Spodoptera frugiperda FKBP-46 is a consensus p53 motif binding protein.

Mohareer K, Sahdev S, Hasnain SE.

J Cell Biochem. 2013 Apr;114(4):899-907. doi: 10.1002/jcb.24429.

PMID:
23097306
35.

Massive gene acquisitions in Mycobacterium indicus pranii provide a perspective on mycobacterial evolution.

Saini V, Raghuvanshi S, Khurana JP, Ahmed N, Hasnain SE, Tyagi AK, Tyagi AK.

Nucleic Acids Res. 2012 Nov;40(21):10832-50. doi: 10.1093/nar/gks793. Epub 2012 Sep 10.

36.

Mycobacterium tuberculosis DosR regulon gene Rv0079 encodes a putative, 'dormancy associated translation inhibitor (DATIN)'.

Kumar A, Majid M, Kunisch R, Rani PS, Qureshi IA, Lewin A, Hasnain SE, Ahmed N.

PLoS One. 2012;7(6):e38709. doi: 10.1371/journal.pone.0038709. Epub 2012 Jun 13.

37.

Comparative genomic and proteomic analyses of PE/PPE multigene family of Mycobacterium tuberculosis H₃₇Rv and H₃₇Ra reveal novel and interesting differences with implications in virulence.

Kohli S, Singh Y, Sharma K, Mittal A, Ehtesham NZ, Hasnain SE.

Nucleic Acids Res. 2012 Aug;40(15):7113-22. doi: 10.1093/nar/gks465. Epub 2012 May 22.

38.

Transcriptional regulation of Mycobacterium tuberculosis PE/PPE genes: a molecular switch to virulence?

Mohareer K, Tundup S, Hasnain SE.

J Mol Microbiol Biotechnol. 2011;21(3-4):97-109. doi: 10.1159/000329489. Epub 2012 Jan 31. Review.

PMID:
22286037
39.

Modern and ancestral genotypes of Mycobacterium tuberculosis from Andhra Pradesh, India.

Thomas SK, Iravatham CC, Moni BH, Kumar A, Archana BV, Majid M, Priyadarshini Y, Rani PS, Valluri V, Hasnain SE, Ahmed N.

PLoS One. 2011;6(11):e27584. doi: 10.1371/journal.pone.0027584. Epub 2011 Nov 17.

40.

The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: perhaps more?

Akhter Y, Ehebauer MT, Mukhopadhyay S, Hasnain SE.

Biochimie. 2012 Jan;94(1):110-6. doi: 10.1016/j.biochi.2011.09.026. Epub 2011 Oct 12. Review.

PMID:
22005451
41.

Climate change and infectious diseases--impact of global warming and climate change on infectious diseases: myth or reality?

Hasnain SE, Friedrich B, Mettenleiter T, Dobrindt U, Hacker J.

Int J Med Microbiol. 2012 Jan;302(1):1-3. doi: 10.1016/j.ijmm.2011.09.011. Epub 2011 Oct 14. No abstract available.

PMID:
22000493
42.

Baculovirus p35 gene is oppositely regulated by P53 and AP-1 like factors in Spodoptera frugiperda.

Mohareer K, Sahdev S, Hasnain SE.

Biochem Biophys Res Commun. 2011 Nov 4;414(4):688-93. doi: 10.1016/j.bbrc.2011.09.133. Epub 2011 Oct 2.

PMID:
21986530
43.

The translation initiation factor, PeIF5B, from Pisum sativum displays chaperone activity.

Suragani M, Rasheedi S, Hasnain SE, Ehtesham NZ.

Biochem Biophys Res Commun. 2011 Oct 22;414(2):390-6. doi: 10.1016/j.bbrc.2011.09.085. Epub 2011 Sep 21.

PMID:
21964295
44.

Concurrent proinflammatory and apoptotic activity of a Helicobacter pylori protein (HP986) points to its role in chronic persistence.

Alvi A, Ansari SA, Ehtesham NZ, Rizwan M, Devi S, Sechi LA, Qureshi IA, Hasnain SE, Ahmed N.

PLoS One. 2011;6(7):e22530. doi: 10.1371/journal.pone.0022530. Epub 2011 Jul 15.

45.

Synergy between the N-terminal and C-terminal domains of Mycobacterium tuberculosis HupB is essential for high-affinity binding, DNA supercoiling and inhibition of RecA-promoted strand exchange.

Sharadamma N, Khan K, Kumar S, Patil KN, Hasnain SE, Muniyappa K.

FEBS J. 2011 Sep;278(18):3447-62. doi: 10.1111/j.1742-4658.2011.08267.x. Epub 2011 Aug 24.

46.

Treatment end point determinants for pulmonary tuberculosis: human resistin as a surrogate biomarker.

Ehtesham NZ, Nasiruddin M, Alvi A, Kumar BK, Ahmed N, Peri S, Murthy KJ, Hasnain SE.

Tuberculosis (Edinb). 2011 Jul;91(4):293-9. doi: 10.1016/j.tube.2011.04.007. Epub 2011 May 24.

PMID:
21606003
47.

Translating advances in genomic research into clinical practice: the challenges ahead.

Hasnain SE, Banerjee S, Ehtesham NZ.

Med Princ Pract. 2011;20(4):392-4. doi: 10.1159/000324877. Epub 2011 May 11. No abstract available.

48.

Molecular epidemiology of tuberculosis in India: moving forward with a systems biology approach.

Ahmed N, Hasnain SE.

Tuberculosis (Edinb). 2011 Sep;91(5):407-13. doi: 10.1016/j.tube.2011.03.006. Epub 2011 Apr 21.

PMID:
21514230
49.

A link between mitochondrial DNA haplogroup and ischemia.

Hasnain SE.

Med Princ Pract. 2011;20(3):201-2. doi: 10.1159/000323839. Epub 2011 Mar 29. No abstract available.

50.

Iron acquisition, assimilation and regulation in mycobacteria.

Banerjee S, Farhana A, Ehtesham NZ, Hasnain SE.

Infect Genet Evol. 2011 Jul;11(5):825-38. doi: 10.1016/j.meegid.2011.02.016. Epub 2011 Mar 22. Review.

PMID:
21414421

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