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Items: 1 to 50 of 176

1.

Discovery of O-Linked Carbohydrate on HIV-1 Envelope and Its Role in Shielding against One Category of Broadly Neutralizing Antibodies.

Silver ZA, Antonopoulos A, Haslam SM, Dell A, Dickinson GM, Seaman MS, Desrosiers RC.

Cell Rep. 2020 Feb 11;30(6):1862-1869.e4. doi: 10.1016/j.celrep.2020.01.056.

PMID:
32049016
2.

Insights into the hyperglycosylation of human chorionic gonadotropin revealed by glycomics analysis.

Ibeto L, Antonopoulos A, Grassi P, Pang PC, Panico M, Bobdiwala S, Al-Memar M, Davis P, Davis M, Norman Taylor J, Almeida P, Johnson MR, Harvey R, Bourne T, Seckl M, Clark G, Haslam SM, Dell A.

PLoS One. 2020 Feb 11;15(2):e0228507. doi: 10.1371/journal.pone.0228507. eCollection 2020.

3.

Glycan biomarkers for Alzheimer disease correlate with T-tau and P-tau in cerebrospinal fluid in subjective cognitive impairment.

Schedin-Weiss S, Gaunitz S, Sui P, Chen Q, Haslam SM, Blennow K, Winblad B, Dell A, Tjernberg LO.

FEBS J. 2019 Dec 30. doi: 10.1111/febs.15197. [Epub ahead of print]

PMID:
31889402
4.

East-Asian Helicobacter pylori strains synthesize heptan-deficient lipopolysaccharide.

Li H, Marceau M, Yang T, Liao T, Tang X, Hu R, Xie Y, Tang H, Tay A, Shi Y, Shen Y, Yang T, Pi X, Lamichhane B, Luo Y, Debowski AW, Nilsson HO, Haslam SM, Mulloy B, Dell A, Stubbs KA, Marshall BJ, Benghezal M.

PLoS Genet. 2019 Nov 20;15(11):e1008497. doi: 10.1371/journal.pgen.1008497. eCollection 2019 Nov.

5.

Site-specific glycoproteomic characterization of ES-62: The major secreted product of the parasitic worm Acanthocheilonema viteae.

North SJ, Botchway K, Doonan J, Lumb FE, Dell A, Harnett W, Haslam SM.

Glycobiology. 2019 Jul 19;29(8):562-571. doi: 10.1093/glycob/cwz035.

6.

Serum IgA1 shows increased levels of α2,6-linked sialic acid in breast cancer.

Lomax-Browne HJ, Robertson C, Antonopoulos A, Leathem AJC, Haslam SM, Dell A, Dwek MV.

Interface Focus. 2019 Apr 6;9(2):20180079. doi: 10.1098/rsfs.2018.0079. Epub 2019 Feb 15.

7.

Human B Cell Differentiation Is Characterized by Progressive Remodeling of O-Linked Glycans.

Giovannone N, Antonopoulos A, Liang J, Geddes Sweeney J, Kudelka MR, King SL, Lee GS, Cummings RD, Dell A, Barthel SR, Widlund HR, Haslam SM, Dimitroff CJ.

Front Immunol. 2018 Dec 14;9:2857. doi: 10.3389/fimmu.2018.02857. eCollection 2018.

8.

Publisher Correction: Host and viral determinants of influenza A virus species specificity.

Long JS, Mistry B, Haslam SM, Barclay WS.

Nat Rev Microbiol. 2019 Jan;17(2):124. doi: 10.1038/s41579-018-0140-y.

PMID:
30560932
9.

Host and viral determinants of influenza A virus species specificity.

Long JS, Mistry B, Haslam SM, Barclay WS.

Nat Rev Microbiol. 2019 Jan;17(2):67-81. doi: 10.1038/s41579-018-0115-z. Review. Erratum in: Nat Rev Microbiol. 2018 Dec 18;:.

PMID:
30487536
10.

Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion.

Wang SS, Gao X, Solar VD, Yu X, Antonopoulos A, Friedman AE, Matich EK, Atilla-Gokcumen GE, Nasirikenari M, Lau JT, Dell A, Haslam SM, Laine RA, Matta KL, Neelamegham S.

Cell Chem Biol. 2018 Dec 20;25(12):1519-1532.e5. doi: 10.1016/j.chembiol.2018.09.012. Epub 2018 Oct 18.

11.

The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants.

El Jellas K, Johansson BB, Fjeld K, Antonopoulos A, Immervoll H, Choi MH, Hoem D, Lowe ME, Lombardo D, Njølstad PR, Dell A, Mas E, Haslam SM, Molven A.

J Biol Chem. 2018 Dec 14;293(50):19476-19491. doi: 10.1074/jbc.RA118.001934. Epub 2018 Oct 12.

12.

XBP1s activation can globally remodel N-glycan structure distribution patterns.

Wong MY, Chen K, Antonopoulos A, Kasper BT, Dewal MB, Taylor RJ, Whittaker CA, Hein PP, Dell A, Genereux JC, Haslam SM, Mahal LK, Shoulders MD.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10089-E10098. doi: 10.1073/pnas.1805425115. Epub 2018 Oct 10.

13.

Loss of GCNT2/I-branched glycans enhances melanoma growth and survival.

Sweeney JG, Liang J, Antonopoulos A, Giovannone N, Kang S, Mondala TS, Head SR, King SL, Tani Y, Brackett D, Dell A, Murphy GF, Haslam SM, Widlund HR, Dimitroff CJ.

Nat Commun. 2018 Aug 22;9(1):3368. doi: 10.1038/s41467-018-05795-0.

14.

Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans.

Giovannone N, Liang J, Antonopoulos A, Geddes Sweeney J, King SL, Pochebit SM, Bhattacharyya N, Lee GS, Dell A, Widlund HR, Haslam SM, Dimitroff CJ.

Nat Commun. 2018 Aug 17;9(1):3287. doi: 10.1038/s41467-018-05770-9.

15.

Photoactivable Glycolipid Antigens Generate Stable Conjugates with CD1d for Invariant Natural Killer T Cell Activation.

Veerapen N, Kharkwal SS, Jervis P, Bhowruth V, Besra AK, North SJ, Haslam SM, Dell A, Hobrath J, Quaid PJ, Moynihan PJ, Cox LR, Kharkwal H, Zauderer M, Besra GS, Porcelli SA.

Bioconjug Chem. 2018 Sep 19;29(9):3161-3173. doi: 10.1021/acs.bioconjchem.8b00484. Epub 2018 Aug 23.

16.

Towards automation of glycomic profiling of complex biological materials.

Shubhakar A, Pang PC, Fernandes DL, Dell A, Spencer DIR, Haslam SM.

Glycoconj J. 2018 Jun;35(3):311-321. doi: 10.1007/s10719-018-9825-8. Epub 2018 Jun 16.

PMID:
29909447
17.

Engineering and dissecting the glycosylation pathway of a streptococcal serine-rich repeat adhesion.

Zhu F, Zhang H, Yang T, Haslam SM, Dell A, Wu H.

J Biol Chem. 2018 Mar 30;293(13):4952. doi: 10.1074/jbc.AAC118.002681. No abstract available.

18.

Exteriorisation of Mannoses on Human Erythrocyte Membrane Skeleton Provides 'Eat Me' Signals for Oxidatively Damaged Cells to be Cleared By Macrophages: A Pathway Mediating Hemolysis in Sickle Cell Disease.

Vickers MA, Barker RN, Cao H, Wassall HJ, Forrester MA, Hall LS, Moss M, Henderson S, Konieczny G, Beverly M, Shepherd J, Haslam SM, Rees DC, Wilson HM, Tampakis D, Williams ML.

Blood. 2017 Dec 7;130(Suppl_1):919. doi: 10.1182/blood.V130.Suppl_1.919.919.

PMID:
31909782
19.

Human Immunodeficiency Virus and Simian Immunodeficiency Virus Maintain High Levels of Infectivity in the Complete Absence of Mucin-Type O-Glycosylation.

Termini JM, Church ES, Silver ZA, Haslam SM, Dell A, Desrosiers RC.

J Virol. 2017 Sep 12;91(19). pii: e01228-17. doi: 10.1128/JVI.01228-17. Print 2017 Oct 1.

20.

Insights from the redefinition of Helicobacter pylori lipopolysaccharide O-antigen and core-oligosaccharide domains.

Li H, Yang T, Liao T, Debowski AW, Nilsson HO, Haslam SM, Dell A, Stubbs KA, Marshall BJ, Benghezal M.

Microb Cell. 2017 Apr 25;4(5):175-178. doi: 10.15698/mic2017.05.574.

21.

HEK293T cell lines defective for O-linked glycosylation.

Termini JM, Silver ZA, Connor B, Antonopoulos A, Haslam SM, Dell A, Desrosiers RC.

PLoS One. 2017 Jun 27;12(6):e0179949. doi: 10.1371/journal.pone.0179949. eCollection 2017.

22.

Effects of altered sialic acid biosynthesis on N-linked glycan branching and cell surface interactions.

Pham ND, Pang PC, Krishnamurthy S, Wands AM, Grassi P, Dell A, Haslam SM, Kohler JJ.

J Biol Chem. 2017 Jun 9;292(23):9637-9651. doi: 10.1074/jbc.M116.764597. Epub 2017 Apr 19.

23.

The redefinition of Helicobacter pylori lipopolysaccharide O-antigen and core-oligosaccharide domains.

Li H, Yang T, Liao T, Debowski AW, Nilsson HO, Fulurija A, Haslam SM, Mulloy B, Dell A, Stubbs KA, Marshall BJ, Benghezal M.

PLoS Pathog. 2017 Mar 17;13(3):e1006280. doi: 10.1371/journal.ppat.1006280. eCollection 2017 Mar.

24.

Characterization of H type 1 and type 1 N-acetyllactosamine glycan epitopes on ovarian cancer specifically recognized by the anti-glycan monoclonal antibody mAb-A4.

Choo M, Tan HL, Ding V, Castangia R, Belgacem O, Liau B, Hartley-Tassell L, Haslam SM, Dell A, Choo A.

J Biol Chem. 2017 Apr 14;292(15):6163-6176. doi: 10.1074/jbc.M116.768887. Epub 2017 Feb 6.

25.

Partial correction of neutrophil dysfunction by oral galactose therapy in glycogen storage disease type Ib.

Letkemann R, Wittkowski H, Antonopoulos A, Podskabi T, Haslam SM, Föll D, Dell A, Marquardt T.

Int Immunopharmacol. 2017 Mar;44:216-225. doi: 10.1016/j.intimp.2017.01.020. Epub 2017 Jan 23.

26.

Engineering and Dissecting the Glycosylation Pathway of a Streptococcal Serine-rich Repeat Adhesin.

Zhu F, Zhang H, Yang T, Haslam SM, Dell A, Wu H.

J Biol Chem. 2016 Dec 30;291(53):27354-27363. doi: 10.1074/jbc.M116.752998. Erratum in: J Biol Chem. 2018 Mar 30;293(13):4952.

27.

The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data.

Liu Y, McBride R, Stoll M, Palma AS, Silva L, Agravat S, Aoki-Kinoshita KF, Campbell MP, Costello CE, Dell A, Haslam SM, Karlsson NG, Khoo KH, Kolarich D, Novotny MV, Packer NH, Ranzinger R, Rapp E, Rudd PM, Struwe WB, Tiemeyer M, Wells L, York WS, Zaia J, Kettner C, Paulson JC, Feizi T, Smith DF.

Glycobiology. 2017 Apr;27(4):280-284. Epub 2016 Nov 22.

28.

The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets.

Struwe WB, Agravat S, Aoki-Kinoshita KF, Campbell MP, Costello CE, Dell A, Ten Feizi, Haslam SM, Karlsson NG, Khoo KH, Kolarich D, Liu Y, McBride R, Novotny MV, Packer NH, Paulson JC, Rapp E, Ranzinger R, Rudd PM, Smith DF, Tiemeyer M, Wells L, York WS, Zaia J, Kettner C.

Glycobiology. 2016 Sep;26(9):907-910. Epub 2016 Sep 21.

29.

Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding.

Panico M, Bouché L, Binet D, O'Connor MJ, Rahman D, Pang PC, Canis K, North SJ, Desrosiers RC, Chertova E, Keele BF, Bess JW Jr, Lifson JD, Haslam SM, Dell A, Morris HR.

Sci Rep. 2016 Sep 8;6:32956. doi: 10.1038/srep32956.

30.

New Helical Binding Domain Mediates a Glycosyltransferase Activity of a Bifunctional Protein.

Zhang H, Zhou M, Yang T, Haslam SM, Dell A, Wu H.

J Biol Chem. 2016 Oct 14;291(42):22106-22117. Epub 2016 Aug 17.

31.

The human fetoembryonic defense system hypothesis: Twenty years on.

Pang PC, Haslam SM, Dell A, Clark GF.

Mol Aspects Med. 2016 Oct;51:71-88. doi: 10.1016/j.mam.2016.06.002. Epub 2016 Jun 24. Review. No abstract available.

32.

Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis.

Mkhikian H, Mortales CL, Zhou RW, Khachikyan K, Wu G, Haslam SM, Kavarian P, Dell A, Demetriou M.

Elife. 2016 Jun 8;5. pii: e14814. doi: 10.7554/eLife.14814.

33.

Characterization of the N-glycans of female Angiostrongylus cantonensis worms.

Veríssimo CM, Morassutti AL, von Itzstein M, Sutov G, Hartley-Tassell L, McAtamney S, Dell A, Haslam SM, Graeff-Teixeira C.

Exp Parasitol. 2016 Jul;166:137-43. doi: 10.1016/j.exppara.2016.04.012. Epub 2016 Apr 20.

34.

Evidence for Differential Glycosylation of Trophoblast Cell Types.

Chen Q, Pang PC, Cohen ME, Longtine MS, Schust DJ, Haslam SM, Blois SM, Dell A, Clark GF.

Mol Cell Proteomics. 2016 Jun;15(6):1857-66. doi: 10.1074/mcp.M115.055798. Epub 2016 Feb 29.

35.

Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin-Dependent Rolling in the Multistep Leukocyte Adhesion Cascade.

Mondal N, Stolfa G, Antonopoulos A, Zhu Y, Wang SS, Buffone A Jr, Atilla-Gokcumen GE, Haslam SM, Dell A, Neelamegham S.

Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):718-27. doi: 10.1161/ATVBAHA.115.306748. Epub 2016 Feb 11.

36.

Glycoproteomic studies of IgE from a novel hyper IgE syndrome linked to PGM3 mutation.

Wu G, Hitchen PG, Panico M, North SJ, Barbouche MR, Binet D, Morris HR, Dell A, Haslam SM.

Glycoconj J. 2016 Jun;33(3):447-56. doi: 10.1007/s10719-015-9638-y. Epub 2015 Dec 19.

37.

Bovine Herpesvirus 4 Modulates Its β-1,6-N-Acetylglucosaminyltransferase Activity through Alternative Splicing.

Lété C, Markine-Goriaynoff N, Machiels B, Pang PC, Xiao X, Canis K, Suzuki M, Fukuda M, Dell A, Haslam SM, Vanderplasschen A, Gillet L.

J Virol. 2015 Dec 9;90(4):2039-51. doi: 10.1128/JVI.01722-15. Print 2016 Feb 15.

38.

Cellular O-Glycome Reporter/Amplification to explore O-glycans of living cells.

Kudelka MR, Antonopoulos A, Wang Y, Duong DM, Song X, Seyfried NT, Dell A, Haslam SM, Cummings RD, Ju T.

Nat Methods. 2016 Jan;13(1):81-6. doi: 10.1038/nmeth.3675. Epub 2015 Nov 30.

39.

Global N-linked Glycosylation is Not Significantly Impaired in Myoblasts in Congenital Myasthenic Syndromes Caused by Defective Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1).

Chen Q, Müller JS, Pang PC, Laval SH, Haslam SM, Lochmüller H, Dell A.

Biomolecules. 2015 Oct 16;5(4):2758-81. doi: 10.3390/biom5042758.

40.

XBP1s Links the Unfolded Protein Response to the Molecular Architecture of Mature N-Glycans.

Dewal MB, DiChiara AS, Antonopoulos A, Taylor RJ, Harmon CJ, Haslam SM, Dell A, Shoulders MD.

Chem Biol. 2015 Oct 22;22(10):1301-12. doi: 10.1016/j.chembiol.2015.09.006.

41.

GlyTouCan 1.0--The international glycan structure repository.

Aoki-Kinoshita K, Agravat S, Aoki NP, Arpinar S, Cummings RD, Fujita A, Fujita N, Hart GM, Haslam SM, Kawasaki T, Matsubara M, Moreman KW, Okuda S, Pierce M, Ranzinger R, Shikanai T, Shinmachi D, Solovieva E, Suzuki Y, Tsuchiya S, Yamada I, York WS, Zaia J, Narimatsu H.

Nucleic Acids Res. 2016 Jan 4;44(D1):D1237-42. doi: 10.1093/nar/gkv1041. Epub 2015 Oct 17.

42.

The zebrafish galectins Drgal1-L2 and Drgal3-L1 bind in vitro to the infectious hematopoietic necrosis virus (IHNV) glycoprotein and reduce viral adhesion to fish epithelial cells.

Nita-Lazar M, Mancini J, Feng C, González-Montalbán N, Ravindran C, Jackson S, de Las Heras-Sánchez A, Giomarelli B, Ahmed H, Haslam SM, Wu G, Dell A, Ammayappan A, Vakharia VN, Vasta GR.

Dev Comp Immunol. 2016 Feb;55:241-252. doi: 10.1016/j.dci.2015.09.007. Epub 2015 Sep 30.

43.

Enhanced Aromatic Sequons Increase Oligosaccharyltransferase Glycosylation Efficiency and Glycan Homogeneity.

Murray AN, Chen W, Antonopoulos A, Hanson SR, Wiseman RL, Dell A, Haslam SM, Powers DL, Powers ET, Kelly JW.

Chem Biol. 2015 Aug 20;22(8):1052-62. doi: 10.1016/j.chembiol.2015.06.017. Epub 2015 Jul 16.

44.

The Cytotoxicity of Elderberry Ribosome-Inactivating Proteins Is Not Solely Determined by Their Protein Translation Inhibition Activity.

Shang C, Chen Q, Dell A, Haslam SM, De Vos WH, Van Damme EJ.

PLoS One. 2015 Jul 6;10(7):e0132389. doi: 10.1371/journal.pone.0132389. eCollection 2015.

45.

Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate.

Stansell E, Panico M, Canis K, Pang PC, Bouché L, Binet D, O'Connor MJ, Chertova E, Bess J, Lifson JD, Haslam SM, Morris HR, Desrosiers RC, Dell A.

PLoS One. 2015 Apr 27;10(4):e0124784. doi: 10.1371/journal.pone.0124784. eCollection 2015.

46.

Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease.

Ersek A, Xu K, Antonopoulos A, Butters TD, Santo AE, Vattakuzhi Y, Williams LM, Goudevenou K, Danks L, Freidin A, Spanoudakis E, Parry S, Papaioannou M, Hatjiharissi E, Chaidos A, Alonzi DS, Twigg G, Hu M, Dwek RA, Haslam SM, Roberts I, Dell A, Rahemtulla A, Horwood NJ, Karadimitris A.

J Clin Invest. 2015 Jun;125(6):2279-92. doi: 10.1172/JCI59987. Epub 2015 Apr 27.

47.

MKAN27435 is required for the biosynthesis of higher subclasses of lipooligosaccharides in Mycobacterium kansasii.

Nataraj V, Pang PC, Haslam SM, Veerapen N, Minnikin DE, Dell A, Besra GS, Bhatt A.

PLoS One. 2015 Apr 20;10(3):e0122804. doi: 10.1371/journal.pone.0122804. eCollection 2015.

48.

Annotation of glycomics MS and MS/MS spectra using the GlycoWorkbench software tool.

Damerell D, Ceroni A, Maass K, Ranzinger R, Dell A, Haslam SM.

Methods Mol Biol. 2015;1273:3-15. doi: 10.1007/978-1-4939-2343-4_1.

PMID:
25753699
49.

ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes.

Mondal N, Buffone A Jr, Stolfa G, Antonopoulos A, Lau JT, Haslam SM, Dell A, Neelamegham S.

Blood. 2015 Jan 22;125(4):687-96. doi: 10.1182/blood-2014-07-588590. Epub 2014 Dec 10.

50.

Systemic blockade of sialylation in mice with a global inhibitor of sialyltransferases.

Macauley MS, Arlian BM, Rillahan CD, Pang PC, Bortell N, Marcondes MC, Haslam SM, Dell A, Paulson JC.

J Biol Chem. 2014 Dec 19;289(51):35149-58. doi: 10.1074/jbc.M114.606517. Epub 2014 Nov 3.

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