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Items: 1 to 50 of 125

1.

Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes.

Dirice E, Kahraman S, De Jesus DF, El Ouaamari A, Basile G, Baker RL, Yigit B, Piehowski PD, Kim MJ, Dwyer AJ, Ng RWS, Schuster C, Vethe H, Martinov T, Ishikawa Y, Teo AKK, Smith RD, Hu J, Haskins K, Serwold T, Qian WJ, Fife BT, Kissler S, Kulkarni RN.

Nat Metab. 2019 May;1(5):509-518. doi: 10.1038/s42255-019-0061-8. Epub 2019 May 6.

2.

Hybrid Insulin Peptides Are Autoantigens in Type 1 Diabetes.

Baker RL, Rihanek M, Hohenstein AC, Nakayama M, Michels A, Gottlieb PA, Haskins K, Delong T.

Diabetes. 2019 Sep;68(9):1830-1840. doi: 10.2337/db19-0128. Epub 2019 Jun 7.

PMID:
31175101
3.

Hybrid insulin peptides are neo-epitopes for CD4 T cells in autoimmune diabetes.

Baker RL, Jamison BL, Haskins K.

Curr Opin Endocrinol Diabetes Obes. 2019 Aug;26(4):195-200. doi: 10.1097/MED.0000000000000490.

4.

Nanoparticles Containing an Insulin-ChgA Hybrid Peptide Protect from Transfer of Autoimmune Diabetes by Shifting the Balance between Effector T Cells and Regulatory T Cells.

Jamison BL, Neef T, Goodspeed A, Bradley B, Baker RL, Miller SD, Haskins K.

J Immunol. 2019 Jul 1;203(1):48-57. doi: 10.4049/jimmunol.1900127. Epub 2019 May 20.

PMID:
31109955
5.

CD11c+ Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes.

Sandor AM, Lindsay RS, Dyjack N, Whitesell JC, Rios C, Bradley BJ, Haskins K, Serreze DV, Geurts AM, Chen YG, Seibold MA, Jacobelli J, Friedman RS.

Front Immunol. 2019 Jan 31;10:99. doi: 10.3389/fimmu.2019.00099. eCollection 2019.

6.

Identification of Hybrid Insulin Peptides (HIPs) in Mouse and Human Islets by Mass Spectrometry.

Wiles TA, Powell R, Michel R, Beard KS, Hohenstein A, Bradley B, Reisdorph N, Haskins K, Delong T.

J Proteome Res. 2019 Mar 1;18(3):814-825. doi: 10.1021/acs.jproteome.8b00875. Epub 2019 Jan 3.

PMID:
30585061
7.

Tissue Crosstalk in T1D: Is Insulin Special?

Jamison BL, Haskins K.

Immunity. 2018 Sep 18;49(3):394-396. doi: 10.1016/j.immuni.2018.09.001.

8.

CD4 T Cells Reactive to Hybrid Insulin Peptides Are Indicators of Disease Activity in the NOD Mouse.

Baker RL, Jamison BL, Wiles TA, Lindsay RS, Barbour G, Bradley B, Delong T, Friedman RS, Nakayama M, Haskins K.

Diabetes. 2018 Sep;67(9):1836-1846. doi: 10.2337/db18-0200. Epub 2018 Jul 5.

9.

Evaluating the Use of KIM-1 in Drug Development and Research Following FDA Qualification.

Chen R, Sanyal S, Thompson A, Ix JH, Haskins K, Muldowney L, Amur S.

Clin Pharmacol Ther. 2018 Dec;104(6):1175-1181. doi: 10.1002/cpt.1093. Epub 2018 May 15.

10.

Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Babon JAB, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC.

Nat Med. 2017 Aug 4;23(8):1004. doi: 10.1038/nm0817-1004a. No abstract available.

11.

Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC.

Nat Med. 2017 Feb 7;23(2):264. doi: 10.1038/nm0217-264a. No abstract available.

PMID:
28170374
12.

Does hybridization of endophytic symbionts in a native grass increase fitness in resource-limited environments?

Faeth SH, Oberhofer M, Saari S, Haskins KE, Shymanovich T.

Ecology. 2017 Jan;98(1):138-149. doi: 10.1002/ecy.1626.

PMID:
28052394
13.

Editorial overview: Autoimmunity.

Haskins K, Buckner JH.

Curr Opin Immunol. 2016 Dec;43:v-vii. doi: 10.1016/j.coi.2016.10.002. Epub 2016 Nov 10. No abstract available.

PMID:
27839940
14.

An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse.

Wiles TA, Delong T, Baker RL, Bradley B, Barbour G, Powell RL, Reisdorph N, Haskins K.

J Autoimmun. 2017 Mar;78:11-18. doi: 10.1016/j.jaut.2016.10.007. Epub 2016 Oct 29.

15.

Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC.

Nat Med. 2016 Dec;22(12):1482-1487. doi: 10.1038/nm.4203. Epub 2016 Oct 31. Erratum in: Nat Med. 2017 Feb 7;23 (2):264. Nat Med. 2017 Aug 4;23 (8):1004.

16.

The Evolution of Epigenetics: From Prokaryotes to Humans and Its Biological Consequences.

Willbanks A, Leary M, Greenshields M, Tyminski C, Heerboth S, Lapinska K, Haskins K, Sarkar S.

Genet Epigenet. 2016 Aug 3;8:25-36. doi: 10.4137/GEG.S31863. eCollection 2016. Review.

17.

Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion.

Delong T, Wiles TA, Baker RL, Bradley B, Barbour G, Reisdorph R, Armstrong M, Powell RL, Reisdorph N, Kumar N, Elso CM, DeNicola M, Bottino R, Powers AC, Harlan DM, Kent SC, Mannering SI, Haskins K.

Science. 2016 Feb 12;351(6274):711-4. doi: 10.1126/science.aad2791.

18.

Cutting Edge: Nonobese Diabetic Mice Deficient in Chromogranin A Are Protected from Autoimmune Diabetes.

Baker RL, Bradley B, Wiles TA, Lindsay RS, Barbour G, Delong T, Friedman RS, Haskins K.

J Immunol. 2016 Jan 1;196(1):39-43. doi: 10.4049/jimmunol.1501190. Epub 2015 Nov 25.

19.

The T Cell Repertoire-Diversifying Enzyme TSSP Contributes to Thymic Selection of Diabetogenic CD4 T Cell Specificities Reactive to ChgA and IAPP Autoantigens.

Viret C, Mahiddine K, Baker RL, Haskins K, Guerder S.

J Immunol. 2015 Sep 1;195(5):1964-73. doi: 10.4049/jimmunol.1401683. Epub 2015 Jul 24.

20.

Antigen recognition in the islets changes with progression of autoimmune islet infiltration.

Lindsay RS, Corbin K, Mahne A, Levitt BE, Gebert MJ, Wigton EJ, Bradley BJ, Haskins K, Jacobelli J, Tang Q, Krummel MF, Friedman RS.

J Immunol. 2015 Jan 15;194(2):522-30. doi: 10.4049/jimmunol.1400626. Epub 2014 Dec 10.

21.

General parity between trio and pairwise breeding of laboratory mice in static caging.

Kedl RM, Wysocki LJ, Janssen WJ, Born WK, Rosenbaum MD, Granowski J, Kench JA, Fong DL, Switzer LA, Cruse M, Huang H, Jakubzick CV, Kosmider B, Takeda K, Stranova TJ, Klumm RC, Delgado C, Tummala S, De Langhe S, Cambier J, Haskins K, Lenz LL, Curran-Everett D.

J Immunol. 2014 Nov 15;193(10):4757-60. doi: 10.4049/jimmunol.1402306.

22.

Convergence in mycorrhizal fungal communities due to drought, plant competition, parasitism, and susceptibility to herbivory: consequences for fungi and host plants.

Gehring CA, Mueller RC, Haskins KE, Rubow TK, Whitham TG.

Front Microbiol. 2014 Jun 25;5:306. doi: 10.3389/fmicb.2014.00306. eCollection 2014.

23.

Time to look back and to look forward.

Nair KS, Abel ED, Adler SG, Dyck PJ, Gardner TW, Haskins KM, Hotamisligil G, Jensen MD, Krook A, Mandarino LJ, Mitchell BD, Pessin JE, Sowers JR, Sussel L, Wareham N, Vella A.

Diabetes. 2014 Apr;63(4):1169-70. doi: 10.2337/db14-0067. No abstract available.

24.

Patching compliance with full-time vs. part-time occlusion therapy.

Kane J, Biernacki R, Fraine L, Fukuda N, Haskins K, Morrison DG.

Am Orthopt J. 2013;63:19-23. doi: 10.3368/aoj.63.1.19.

PMID:
24260803
25.

Chromogranin A is a T cell antigen in human type 1 diabetes.

Gottlieb PA, Delong T, Baker RL, Fitzgerald-Miller L, Wagner R, Cook G, Rewers MR, Michels A, Haskins K.

J Autoimmun. 2014 May;50:38-41. doi: 10.1016/j.jaut.2013.10.003. Epub 2013 Nov 13.

26.

Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice.

Baker RL, Delong T, Barbour G, Bradley B, Nakayama M, Haskins K.

J Immunol. 2013 Oct 15;191(8):3990-4. doi: 10.4049/jimmunol.1301480. Epub 2013 Sep 16.

27.

A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis.

Cordova KN, Willis VC, Haskins K, Holers VM.

J Immunol. 2013 Feb 15;190(4):1457-65. doi: 10.4049/jimmunol.1201517. Epub 2013 Jan 14.

28.

Novel autoantigens for diabetogenic CD4 T cells in autoimmune diabetes.

Delong T, Baker RL, He J, Haskins K.

Immunol Res. 2013 Mar;55(1-3):167-72. doi: 10.1007/s12026-012-8375-6. Review.

29.

Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.

Delong T, Baker RL, He J, Barbour G, Bradley B, Haskins K.

Diabetes. 2012 Dec;61(12):3239-46. doi: 10.2337/db12-0112. Epub 2012 Aug 21.

30.

T cells interact with T cells via CD40-CD154 to promote autoimmunity in type 1 diabetes.

Baker RL, Mallevaey T, Gapin L, Haskins K.

Eur J Immunol. 2012 Mar;42(3):672-80. doi: 10.1002/eji.201142071.

31.

Strategies to reduce dendritic cell activation through functional biomaterial design.

Hume PS, He J, Haskins K, Anseth KS.

Biomaterials. 2012 May;33(14):3615-25. doi: 10.1016/j.biomaterials.2012.02.009. Epub 2012 Feb 21.

32.

Germline TRAV5D-4 T-cell receptor sequence targets a primary insulin peptide of NOD mice.

Nakayama M, Castoe T, Sosinowski T, He X, Johnson K, Haskins K, Vignali DA, Gapin L, Pollock D, Eisenbarth GS.

Diabetes. 2012 Apr;61(4):857-65. doi: 10.2337/db11-1113. Epub 2012 Feb 7.

33.

The classical dichotomy between presentation of endogenous antigens via the MHC class I pathway and exogenous antigens via the MHC class-II pathway.

Kyewski B, Haskins K.

Curr Opin Immunol. 2012 Feb;24(1):67-70. doi: 10.1016/j.coi.2012.01.013. Epub 2012 Feb 2. No abstract available.

PMID:
22305303
34.

Comparison of the diagnostic accuracy of di-22:6-bis(monoacylglycerol)phosphate and other urinary phospholipids for drug-induced phospholipidosis or tissue injury in the rat.

Thompson KL, Haskins K, Rosenzweig BA, Stewart S, Zhang J, Peters D, Knapton A, Rouse R, Mans D, Colatsky T.

Int J Toxicol. 2012 Jan-Feb;31(1):14-24. doi: 10.1177/1091581811430167. Epub 2012 Jan 19.

PMID:
22267869
35.

Establishing the phylogenetic origin, history, and age of the narrow endemic Viola guadalupensis (Violaceae).

Marcussen T, Blaxland K, Windham MD, Haskins KE, Armstrong F.

Am J Bot. 2011 Dec;98(12):1978-88. doi: 10.3732/ajb.1100208. Epub 2011 Nov 11.

36.

CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes.

Haskins K, Cooke A.

Curr Opin Immunol. 2011 Dec;23(6):739-45. doi: 10.1016/j.coi.2011.08.004. Epub 2011 Sep 12. Review.

37.

Islet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells.

Delong T, Baker RL, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Barbour G, Bradley B, Haskins K.

Diabetes. 2011 Sep;60(9):2325-30. doi: 10.2337/db11-0288. Epub 2011 Jul 6.

38.

Autoimmune-mediated vascular injury occurs prior to sustained hyperglycemia in a murine model of type I diabetes mellitus.

Zimmerman MA, Haskins K, Bradley B, Gilman J, Gamboni-Robertson F, Flores SC.

J Surg Res. 2011 Jun 15;168(2):e195-202. doi: 10.1016/j.jss.2011.01.021. Epub 2011 Feb 26.

39.

Coronary artery dissection: a management dilemma in the district general hospital.

Bougeard AM, Haskins KV.

Emerg Med J. 2010 Feb;27(2):161-3. doi: 10.1136/emj.2008.066209.

PMID:
20156880
40.

Chromogranin A is an autoantigen in type 1 diabetes.

Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K.

Nat Immunol. 2010 Mar;11(3):225-31. doi: 10.1038/ni.1844. Epub 2010 Feb 7.

41.
42.

Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chains.

Zhang L, Jasinski JM, Kobayashi M, Davenport B, Johnson K, Davidson H, Nakayama M, Haskins K, Eisenbarth GS.

J Autoimmun. 2009 Aug;33(1):42-9. doi: 10.1016/j.jaut.2009.02.003. Epub 2009 Mar 16.

43.

Carbon monoxide poisoning measurement.

Harty E, Haskins K, Robinson K.

Emerg Med J. 2008 Dec;25(12):862. doi: 10.1136/emj.2008.061960. No abstract available.

PMID:
19033522
44.

CD40 on NOD CD4 T cells contributes to their activation and pathogenicity.

Baker RL, Wagner DH Jr, Haskins K.

J Autoimmun. 2008 Dec;31(4):385-92. doi: 10.1016/j.jaut.2008.09.001. Epub 2008 Oct 31.

PMID:
18951762
45.
46.

Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity.

Haskins KA, Russell JF, Gaddis N, Dressman HK, Aballay A.

Dev Cell. 2008 Jul;15(1):87-97. doi: 10.1016/j.devcel.2008.05.006.

47.

On the pathogenicity of autoantigen-specific T-cell receptors.

Burton AR, Vincent E, Arnold PY, Lennon GP, Smeltzer M, Li CS, Haskins K, Hutton J, Tisch RM, Sercarz EE, Santamaria P, Workman CJ, Vignali DA.

Diabetes. 2008 May;57(5):1321-30. doi: 10.2337/db07-1129. Epub 2008 Feb 25.

50.

Oxidant stress, immune dysregulation, and vascular function in type I diabetes.

Nicolls MR, Haskins K, Flores SC.

Antioxid Redox Signal. 2007 Jul;9(7):879-89. Review.

PMID:
17508913

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