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Items: 1 to 50 of 268

1.

Comparing the clinical profile of adults and children with Behçet's syndrome in the UK.

Makmur EL, Myers SH, Hanns L, Haskard DO, Brogan P, Ambrose N.

Clin Exp Rheumatol. 2019 May 30. [Epub ahead of print]

PMID:
31172922
2.

An Integrated Chemical Proteomics Approach for Quantitative Profiling of Intracellular ADP-Ribosylation.

Kalesh K, Lukauskas S, Borg AJ, Snijders AP, Ayyappan V, Leung AKL, Haskard DO, DiMaggio PA.

Sci Rep. 2019 Apr 30;9(1):6655. doi: 10.1038/s41598-019-43154-1.

3.

IgM anti-malondialdehyde low density lipoprotein antibody levels indicate coronary heart disease and necrotic core characteristics in the Nordic Diltiazem (NORDIL) study and the Integrated Imaging and Biomarker Study 3 (IBIS-3).

van den Berg VJ, Haskard DO, Fedorowski A, Hartley A, Kardys I, Caga-Anan M, Akkerhuis KM, Oemrawsingh RM, van Geuns RJ, de Jaegere P, van Mieghem N, Regar E, Ligthart JMR, Umans VAWM, Serruys PW, Melander O, Boersma E, Khamis RY.

EBioMedicine. 2018 Oct;36:63-72. doi: 10.1016/j.ebiom.2018.08.023. Epub 2018 Aug 18.

4.

Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling.

Al-Rashed F, Calay D, Lang M, Thornton CC, Bauer A, Kiprianos A, Haskard DO, Seneviratne A, Boyle JJ, Schönthal AH, Wheeler-Jones CP, Mason JC.

Sci Rep. 2018 Apr 19;8(1):6271. doi: 10.1038/s41598-018-24548-z.

5.

Developing a Strategy for Interventional Molecular Imaging of Oxidized Low-Density Lipoprotein in Atherosclerosis.

Pandey SS, Haskard DO, Khamis RY.

Mol Imaging. 2017 Jan-Dec;16:1536012117723788. doi: 10.1177/1536012117723788.

6.

A low balance between microparticles expressing tissue factor pathway inhibitor and tissue factor is associated with thrombosis in Behçet's Syndrome.

Khan E, Ambrose NL, Ahnström J, Kiprianos AP, Stanford MR, Eleftheriou D, Brogan PA, Mason JC, Johns M, Laffan MA, Haskard DO.

Sci Rep. 2016 Dec 7;6:38104. doi: 10.1038/srep38104.

7.

Zebrafish Model for Functional Screening of Flow-Responsive Genes.

Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C, Bowden N, Ashton JP, Walczak H, Firmin D, Krams R, Mason JC, Haskard DO, Sherwin S, Ridger V, Chico TJ, Evans PC.

Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):130-143. doi: 10.1161/ATVBAHA.116.308502. Epub 2016 Nov 10.

8.

High Serum Immunoglobulin G and M Levels Predict Freedom From Adverse Cardiovascular Events in Hypertension: A Nested Case-Control Substudy of the Anglo-Scandinavian Cardiac Outcomes Trial.

Khamis RY, Hughes AD, Caga-Anan M, Chang CL, Boyle JJ, Kojima C, Welsh P, Sattar N, Johns M, Sever P, Mayet J, Haskard DO.

EBioMedicine. 2016 Jul;9:372-380. doi: 10.1016/j.ebiom.2016.06.012. Epub 2016 Jun 20.

9.

Translational interventional cardiology: a new editorial priority for EuroIntervention.

Khamis RY, Haskard DO, Serruys PW.

EuroIntervention. 2016 May 17;12(1):11-3. doi: 10.4244/EIJV12I1A2. No abstract available.

10.

Near Infrared Fluorescence (NIRF) Molecular Imaging of Oxidized LDL with an Autoantibody in Experimental Atherosclerosis.

Khamis RY, Woollard KJ, Hyde GD, Boyle JJ, Bicknell C, Chang SH, Malik TH, Hara T, Mauskapf A, Granger DW, Johnson JL, Ntziachristos V, Matthews PM, Jaffer FA, Haskard DO.

Sci Rep. 2016 Feb 25;6:21785. doi: 10.1038/srep21785.

11.

Mini Bypass and Proinflammatory Leukocyte Activation: A Randomized Controlled Trial.

Nguyen BA, Fiorentino F, Reeves BC, Baig K, Athanasiou T, Anderson JR, Haskard DO, Angelini GD, Evans PC.

Ann Thorac Surg. 2016 Apr;101(4):1454-63. doi: 10.1016/j.athoracsur.2015.09.029. Epub 2015 Nov 18.

PMID:
26602006
12.

A Targeting Microbubble for Ultrasound Molecular Imaging.

Yeh JS, Sennoga CA, McConnell E, Eckersley R, Tang MX, Nourshargh S, Seddon JM, Haskard DO, Nihoyannopoulos P.

PLoS One. 2015 Jul 10;10(7):e0129681. doi: 10.1371/journal.pone.0129681. eCollection 2015.

13.

Quantitative ultrasound molecular imaging.

Yeh JS, Sennoga CA, McConnell E, Eckersley R, Tang MX, Nourshargh S, Seddon JM, Haskard DO, Nihoyannopoulos P.

Ultrasound Med Biol. 2015 Sep;41(9):2478-96. doi: 10.1016/j.ultrasmedbio.2015.04.011. Epub 2015 Jun 1.

PMID:
26044707
14.

The exaggerated inflammatory response in Behçet's syndrome: identification of dysfunctional post-transcriptional regulation of the IFN-γ/CXCL10 IP-10 pathway.

Ambrose N, Khan E, Ravindran R, Lightstone L, Abraham S, Botto M, Johns M, Haskard DO.

Clin Exp Immunol. 2015 Sep;181(3):427-33. doi: 10.1111/cei.12655. Epub 2015 Jul 14.

15.

Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation.

Thornton CC, Al-Rashed F, Calay D, Birdsey GM, Bauer A, Mylroie H, Morley BJ, Randi AM, Haskard DO, Boyle JJ, Mason JC.

Ann Rheum Dis. 2016 Feb;75(2):439-48. doi: 10.1136/annrheumdis-2014-206305. Epub 2015 Jan 9.

16.

PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression.

Iqbal MB, Johns M, Cao J, Liu Y, Yu SC, Hyde GD, Laffan MA, Marchese FP, Cho SH, Clark AR, Gavins FN, Woollard KJ, Blackshear PJ, Mackman N, Dean JL, Boothby M, Haskard DO.

Blood. 2014 Dec 4;124(24):3646-55. doi: 10.1182/blood-2014-07-588046. Epub 2014 Oct 7.

17.

Pegylated interferon-α-2b reduces corticosteroid requirement in patients with Behçet's disease with upregulation of circulating regulatory T cells and reduction of Th17.

Lightman S, Taylor SR, Bunce C, Longhurst H, Lynn W, Moots R, Stanford M, Tomkins-Netzer O, Yang D, Calder VL, Haskard DO.

Ann Rheum Dis. 2015 Jun;74(6):1138-44. doi: 10.1136/annrheumdis-2014-205571. Epub 2014 Sep 30.

18.

Magnetic resonance imaging of vein wall thickness in patients with Behçet's syndrome.

Ambrose N, Pierce IT, Gatehouse PD, Haskard DO, Firmin DN.

Clin Exp Rheumatol. 2014 Jul-Aug;32(4 Suppl 84):S99-102. Epub 2014 Sep 30.

PMID:
25268665
19.

Dynamics of targeted microbubble adhesion under pulsatile compared with steady flow.

Sennoga CA, Seddon JM, Frueh JA, Zhang D, Haskard DO, Eckersley RJ, Tang MX.

Ultrasound Med Biol. 2014 Oct;40(10):2445-57. doi: 10.1016/j.ultrasmedbio.2014.03.015. Epub 2014 Jul 9.

PMID:
25023113
20.

Work-related disability in Behçet's syndrome: a British case series.

Mehta P, Ambrose N, Haskard DO.

Clin Exp Rheumatol. 2014 Jul-Aug;32(4 Suppl 84):S173-4. Epub 2014 Jul 8. No abstract available.

PMID:
25005835
21.

Requirement of JNK1 for endothelial cell injury in atherogenesis.

Amini N, Boyle JJ, Moers B, Warboys CM, Malik TH, Zakkar M, Francis SE, Mason JC, Haskard DO, Evans PC.

Atherosclerosis. 2014 Aug;235(2):613-8. doi: 10.1016/j.atherosclerosis.2014.05.950. Epub 2014 Jun 12.

22.

Steroid-resistant remitting seronegative symmetrical synovitis with pitting oedema associated with gout treated with etanercept.

Mehta P, Chong S, Carulli MT, Haskard DO.

Rheumatology (Oxford). 2014 Oct;53(10):1908-10. doi: 10.1093/rheumatology/keu223. Epub 2014 Jun 6. No abstract available.

PMID:
24907150
23.

Synergistic therapeutic vascular cytoprotection against complement-mediated injury induced via a PKCα-, AMPK-, and CREB-dependent pathway.

Hamdulay SS, Wang B, Calay D, Kiprianos AP, Cole J, Dumont O, Dryden N, Randi AM, Thornton CC, Al-Rashed F, Hoong C, Shamsi A, Liu Z, Holla VR, Boyle JJ, Haskard DO, Mason JC.

J Immunol. 2014 May 1;192(9):4316-27. doi: 10.4049/jimmunol.1301702. Epub 2014 Mar 26.

24.

Disturbed flow promotes endothelial senescence via a p53-dependent pathway.

Warboys CM, de Luca A, Amini N, Luong L, Duckles H, Hsiao S, White A, Biswas S, Khamis R, Chong CK, Cheung WM, Sherwin SJ, Bennett MR, Gil J, Mason JC, Haskard DO, Evans PC.

Arterioscler Thromb Vasc Biol. 2014 May;34(5):985-95. doi: 10.1161/ATVBAHA.114.303415. Epub 2014 Mar 20.

PMID:
24651677
25.

ICAM-2 regulates vascular permeability and N-cadherin localization through ezrin-radixin-moesin (ERM) proteins and Rac-1 signalling.

Amsellem V, Dryden NH, Martinelli R, Gavins F, Almagro LO, Birdsey GM, Haskard DO, Mason JC, Turowski P, Randi AM.

Cell Commun Signal. 2014 Mar 4;12:12. doi: 10.1186/1478-811X-12-12.

26.

Sulforaphane pretreatment prevents systemic inflammation and renal injury in response to cardiopulmonary bypass.

Nguyen B, Luong L, Naase H, Vives M, Jakaj G, Finch J, Boyle J, Mulholland JW, Kwak JH, Pyo S, de Luca A, Athanasiou T, Angelini G, Anderson J, Haskard DO, Evans PC.

J Thorac Cardiovasc Surg. 2014 Aug;148(2):690-697.e3. doi: 10.1016/j.jtcvs.2013.12.048. Epub 2014 Jan 15.

27.

5'-AMP-activated protein kinase-activating transcription factor 1 cascade modulates human monocyte-derived macrophages to atheroprotective functions in response to heme or metformin.

Wan X, Huo Y, Johns M, Piper E, Mason JC, Carling D, Haskard DO, Boyle JJ.

Arterioscler Thromb Vasc Biol. 2013 Nov;33(11):2470-80. doi: 10.1161/ATVBAHA.113.300986. Epub 2013 Sep 19. Erratum in: Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):e80.

PMID:
24051143
28.

Evolution of the Macrophage CD163 Phenotype and Cytokine Profiles in a Human Model of Resolving Inflammation.

Evans BJ, Haskard DO, Sempowksi G, Landis RC.

Int J Inflam. 2013;2013:780502. doi: 10.1155/2013/780502. Epub 2013 May 2.

29.

Haptoglobin Genotype-Dependent Anti-Inflammatory Signaling in CD163(+) Macrophages.

Landis RC, Philippidis P, Domin J, Boyle JJ, Haskard DO.

Int J Inflam. 2013;2013:980327. doi: 10.1155/2013/980327. Epub 2013 Apr 23.

30.

Cezanne regulates inflammatory responses to hypoxia in endothelial cells by targeting TRAF6 for deubiquitination.

Luong le A, Fragiadaki M, Smith J, Boyle J, Lutz J, Dean JL, Harten S, Ashcroft M, Walmsley SR, Haskard DO, Maxwell PH, Walczak H, Pusey C, Evans PC.

Circ Res. 2013 Jun 7;112(12):1583-91. doi: 10.1161/CIRCRESAHA.111.300119. Epub 2013 Apr 5.

PMID:
23564640
31.

Cytoprotective signaling and gene expression in endothelial cells and macrophages-lessons for atherosclerosis.

Haskard DO, Boyle JJ, Evans PC, Mason JC, Randi AM.

Microcirculation. 2013 Apr;20(3):203-16. doi: 10.1111/micc.12020. Review.

PMID:
23121167
32.

Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma.

Barbarulo A, Iansante V, Chaidos A, Naresh K, Rahemtulla A, Franzoso G, Karadimitris A, Haskard DO, Papa S, Bubici C.

Oncogene. 2013 Sep 5;32(36):4231-42. doi: 10.1038/onc.2012.448. Epub 2012 Oct 8.

33.

Differential diagnosis and management of Behçet syndrome.

Ambrose NL, Haskard DO.

Nat Rev Rheumatol. 2013 Feb;9(2):79-89. doi: 10.1038/nrrheum.2012.156. Epub 2012 Sep 25. Review.

PMID:
23007742
34.

Protein kinase Cε activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection.

Dumont O, Mylroie H, Bauer A, Calay D, Sperone A, Thornton C, Hamdulay SS, Ali N, Boyle JJ, Choo JR, Samarel AM, Haskard DO, Randi AM, Evans PC, Mason JC.

Biochem J. 2012 Oct 15;447(2):193-204.

PMID:
22849349
35.

Solid-phase immunoglobulins IgG and IgM activate macrophages with solid-phase IgM acting via a novel scavenger receptor a pathway.

Boyle JJ, Christou I, Iqbal MB, Nguyen AT, Leung VW, Evans PC, Liu Y, Johns M, Kirkham P, Haskard DO.

Am J Pathol. 2012 Jul;181(1):347-61. doi: 10.1016/j.ajpath.2012.03.040. Epub 2012 May 30.

36.

Model IgG monoclonal autoantibody-anti-idiotype pair for dissecting the humoral immune response to oxidized low density lipoprotein.

Chang SH, Johns M, Boyle JJ, McConnell E, Kirkham PA, Bicknell C, Zahoor-ul-Hassan Dogar M, Edwards RJ, Gale-Grant O, Khamis R, Ramkhelawon KV, Haskard DO.

Hybridoma (Larchmt). 2012 Apr;31(2):87-98. doi: 10.1089/hyb.2011.0058.

37.

Evaluation of methods for sizing and counting of ultrasound contrast agents.

Sennoga CA, Yeh JS, Alter J, Stride E, Nihoyannopoulos P, Seddon JM, Haskard DO, Hajnal JV, Tang MX, Eckersley RJ.

Ultrasound Med Biol. 2012 May;38(5):834-45. doi: 10.1016/j.ultrasmedbio.2012.01.012. Epub 2012 Mar 6.

38.

Distinct roles for complement in glomerulonephritis and atherosclerosis revealed in mice with a combination of lupus and hyperlipidemia.

Lewis MJ, Malik TH, Fossati-Jimack L, Carassiti D, Cook HT, Haskard DO, Botto M.

Arthritis Rheum. 2012 Aug;64(8):2707-18. doi: 10.1002/art.34451.

39.

The transcription factor Erg controls endothelial cell quiescence by repressing activity of nuclear factor (NF)-κB p65.

Dryden NH, Sperone A, Martin-Almedina S, Hannah RL, Birdsey GM, Khan ST, Layhadi JA, Mason JC, Haskard DO, Göttgens B, Randi AM.

J Biol Chem. 2012 Apr 6;287(15):12331-42. doi: 10.1074/jbc.M112.346791. Epub 2012 Feb 15.

40.

The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis.

Birdsey GM, Dryden NH, Shah AV, Hannah R, Hall MD, Haskard DO, Parsons M, Mason JC, Zvelebil M, Gottgens B, Ridley AJ, Randi AM.

Blood. 2012 Jan 19;119(3):894-903. doi: 10.1182/blood-2011-04-350025. Epub 2011 Nov 23.

PMID:
22117042
41.

Activating transcription factor 1 directs Mhem atheroprotective macrophages through coordinated iron handling and foam cell protection.

Boyle JJ, Johns M, Kampfer T, Nguyen AT, Game L, Schaer DJ, Mason JC, Haskard DO.

Circ Res. 2012 Jan 6;110(1):20-33. doi: 10.1161/CIRCRESAHA.111.247577. Epub 2011 Nov 3.

42.

Surgical management of chylopericardium and chylothorax in a patient with Behçet's disease.

Al Jaaly E, Baig K, Patni R, Anderson J, Haskard DO.

Clin Exp Rheumatol. 2011 Jul-Aug;29(4 Suppl 67):S68-70. Epub 2011 Sep 27.

PMID:
21968240
43.

Heme induces heme oxygenase 1 via Nrf2: role in the homeostatic macrophage response to intraplaque hemorrhage.

Boyle JJ, Johns M, Lo J, Chiodini A, Ambrose N, Evans PC, Mason JC, Haskard DO.

Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2685-91. doi: 10.1161/ATVBAHA.111.225813.

44.

Resolution of Behçet's syndrome associated pulmonary arterial aneurysms with infliximab.

Schreiber BE, Noor N, Juli CF, Haskard DO.

Semin Arthritis Rheum. 2011 Dec;41(3):482-7. doi: 10.1016/j.semarthrit.2011.02.006. Epub 2011 May 4.

PMID:
21546064
45.

Disturbed blood flow induces RelA expression via c-Jun N-terminal kinase 1: a novel mode of NF-κB regulation that promotes arterial inflammation.

Cuhlmann S, Van der Heiden K, Saliba D, Tremoleda JL, Khalil M, Zakkar M, Chaudhury H, Luong le A, Mason JC, Udalova I, Gsell W, Jones H, Haskard DO, Krams R, Evans PC.

Circ Res. 2011 Apr 15;108(8):950-9. doi: 10.1161/CIRCRESAHA.110.233841. Epub 2011 Feb 24.

PMID:
21350211
46.

Dexamethasone arterializes venous endothelial cells by inducing mitogen-activated protein kinase phosphatase-1: a novel antiinflammatory treatment for vein grafts?

Zakkar M, Luong le A, Chaudhury H, Ruud O, Punjabi PP, Anderson JR, Mullholand JW, Clements AT, Krams R, Foin N, Athanasiou T, Leen EL, Mason JC, Haskard DO, Evans PC.

Circulation. 2011 Feb 8;123(5):524-32. doi: 10.1161/CIRCULATIONAHA.110.979542. Epub 2011 Jan 24.

PMID:
21262999
47.

Endothelial von Willebrand factor regulates angiogenesis.

Starke RD, Ferraro F, Paschalaki KE, Dryden NH, McKinnon TA, Sutton RE, Payne EM, Haskard DO, Hughes AD, Cutler DF, Laffan MA, Randi AM.

Blood. 2011 Jan 20;117(3):1071-80. doi: 10.1182/blood-2010-01-264507. Epub 2010 Nov 3.

48.

The alternative pathway is critical for pathogenic complement activation in endotoxin- and diet-induced atherosclerosis in low-density lipoprotein receptor-deficient mice.

Malik TH, Cortini A, Carassiti D, Boyle JJ, Haskard DO, Botto M.

Circulation. 2010 Nov 9;122(19):1948-56. doi: 10.1161/CIRCULATIONAHA.110.981365. Epub 2010 Oct 25. Erratum in: Circulation. 2011 Dec 6;124(23):e781.

49.

The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells.

Sperone A, Dryden NH, Birdsey GM, Madden L, Johns M, Evans PC, Mason JC, Haskard DO, Boyle JJ, Paleolog EM, Randi AM.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):142-50. doi: 10.1161/ATVBAHA.110.216473. Epub 2010 Oct 21.

PMID:
20966395
50.

In vivo fluorescence imaging of E-selectin: quantitative detection of endothelial activation in a mouse model of arthritis.

Gompels LL, Madden L, Lim NH, Inglis JJ, McConnell E, Vincent TL, Haskard DO, Paleolog EM.

Arthritis Rheum. 2011 Jan;63(1):107-17. doi: 10.1002/art.30082.

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