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Items: 12

1.

Inhibition of T cell activation and function by the adaptor protein CIN85.

Kong MS, Hashimoto-Tane A, Kawashima Y, Sakuma M, Yokosuka T, Kometani K, Onishi R, Carpino N, Ohara O, Kurosaki T, Phua KK, Saito T.

Sci Signal. 2019 Feb 5;12(567). pii: eaav4373. doi: 10.1126/scisignal.aav4373.

PMID:
30723173
2.

Analyzing the Dynamics of Signaling Microclusters.

Hashimoto-Tane A, Yokosuka T, Saito T.

Methods Mol Biol. 2017;1584:51-64. doi: 10.1007/978-1-4939-6881-7_4.

PMID:
28255695
3.

Dynamic Regulation of TCR-Microclusters and the Microsynapse for T Cell Activation.

Hashimoto-Tane A, Saito T.

Front Immunol. 2016 Jun 28;7:255. doi: 10.3389/fimmu.2016.00255. eCollection 2016. Review.

4.

Micro-adhesion rings surrounding TCR microclusters are essential for T cell activation.

Hashimoto-Tane A, Sakuma M, Ike H, Yokosuka T, Kimura Y, Ohara O, Saito T.

J Exp Med. 2016 Jul 25;213(8):1609-25. doi: 10.1084/jem.20151088. Epub 2016 Jun 27.

5.

Nucleic acid sensing by T cells initiates Th2 cell differentiation.

Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T.

Nat Commun. 2014 Apr 10;5:3566. doi: 10.1038/ncomms4566.

PMID:
24717539
6.

Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.

Yokosuka T, Takamatsu M, Kobayashi-Imanishi W, Hashimoto-Tane A, Azuma M, Saito T.

J Exp Med. 2012 Jun 4;209(6):1201-17. doi: 10.1084/jem.20112741. Epub 2012 May 28.

7.

Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation.

Hashimoto-Tane A, Yokosuka T, Sakata-Sogawa K, Sakuma M, Ishihara C, Tokunaga M, Saito T.

Immunity. 2011 Jun 24;34(6):919-31. doi: 10.1016/j.immuni.2011.05.012.

8.

Dynamic regulation of T cell activation and co-stimulation through TCR-microclusters.

Saito T, Yokosuka T, Hashimoto-Tane A.

FEBS Lett. 2010 Dec 15;584(24):4865-71. doi: 10.1016/j.febslet.2010.11.036. Epub 2010 Nov 24. Review.

9.

Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation.

Yokosuka T, Kobayashi W, Takamatsu M, Sakata-Sogawa K, Zeng H, Hashimoto-Tane A, Yagita H, Tokunaga M, Saito T.

Immunity. 2010 Sep 24;33(3):326-39. doi: 10.1016/j.immuni.2010.09.006.

10.

T-cell receptor microclusters critical for T-cell activation are formed independently of lipid raft clustering.

Hashimoto-Tane A, Yokosuka T, Ishihara C, Sakuma M, Kobayashi W, Saito T.

Mol Cell Biol. 2010 Jul;30(14):3421-9. doi: 10.1128/MCB.00160-10. Epub 2010 May 24.

11.

Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation.

Yokosuka T, Kobayashi W, Sakata-Sogawa K, Takamatsu M, Hashimoto-Tane A, Dustin ML, Tokunaga M, Saito T.

Immunity. 2008 Oct 17;29(4):589-601. doi: 10.1016/j.immuni.2008.08.011. Epub 2008 Oct 9.

12.

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

Yokosuka T, Sakata-Sogawa K, Kobayashi W, Hiroshima M, Hashimoto-Tane A, Tokunaga M, Dustin ML, Saito T.

Nat Immunol. 2005 Dec;6(12):1253-62. Epub 2005 Nov 6.

PMID:
16273097

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