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Differential Expression of a Classic Cadherin Directs Tissue-Level Contractile Asymmetry during Neural Tube Closure.

Hashimoto H, Munro E.

Dev Cell. 2019 Oct 21;51(2):158-172.e4. doi: 10.1016/j.devcel.2019.10.001.


Absorption and Metabolism of γ-Oryzanol, a Characteristic Functional Ingredient in Rice Bran.

Sawada K, Rahmania H, Matsuki M, Hashimoto H, Ito J, Miyazawa T, Nakagawa K.

J Nutr Sci Vitaminol (Tokyo). 2019;65(Supplement):S180-S184. doi: 10.3177/jnsv.65.S180.


Hearing impairment and associated morphological changes in pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice.

Fulop DB, Humli V, Szepesy J, Ott V, Reglodi D, Gaszner B, Nemeth A, Szirmai A, Tamas L, Hashimoto H, Zelles T, Tamas A.

Sci Rep. 2019 Oct 10;9(1):14598. doi: 10.1038/s41598-019-50775-z.


Efficacy of belt electrode skeletal muscle electrical stimulation on reducing the rate of muscle volume loss in critically ill patients: A randomized controlled trial.

Nakamura K, Kihata A, Naraba H, Kanda N, Takahashi Y, Sonoo T, Hashimoto H, Morimura N.

J Rehabil Med. 2019 Oct 3;51(9):705-711. doi: 10.2340/16501977-2594.


Characteristics of cognitive function evaluation using the Montreal cognitive assessment in a cerebrospinal fluid tap test in patients with idiopathic normal pressure hydrocephalus.

Matsuoka T, Kawano S, Fujimoto K, Kawahara M, Hashimoto H.

Clin Neurol Neurosurg. 2019 Sep 12;186:105524. doi: 10.1016/j.clineuro.2019.105524. [Epub ahead of print]


Autism-associated protein kinase D2 regulates embryonic cortical neuron development.

Matsumura K, Baba M, Nagayasu K, Yamamoto K, Kondo M, Kitagawa K, Takemoto T, Seiriki K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Kuriu T, Iguchi T, Sato M, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T.

Biochem Biophys Res Commun. 2019 Nov 12;519(3):626-632. doi: 10.1016/j.bbrc.2019.09.048. Epub 2019 Sep 18.


Dietary capsaicin-mediated attenuation of hypertension in a rat model of renovascular hypertension.

Segawa Y, Hashimoto H, Maruyama S, Shintani M, Ohno H, Nakai Y, Osera T, Kurihara N.

Clin Exp Hypertens. 2019 Sep 13:1-8. doi: 10.1080/10641963.2019.1665676. [Epub ahead of print]


Myocardial calcification in a patient with B-lymphoblastic leukemia accompanied by tumor lysis syndrome.

Usui G, Hashimoto H, Uchibori Y, Usuki K, Horiuchi H, Morikawa T.

Cardiovasc Pathol. 2019 Aug 7;43:107146. doi: 10.1016/j.carpath.2019.07.005. [Epub ahead of print]


Case of fertility treatment-induced Stevens-Johnson syndrome with a severe ocular complication.

Hashimoto H, Miyachi H, Kataoka K, Maru Y, Togawa Y, Matsue H.

J Dermatol. 2019 Sep 5. doi: 10.1111/1346-8138.15072. [Epub ahead of print]


Functional and Structural Analyses of trans C-Methyltransferase in Fungal Polyketide Biosynthesis.

Kishimoto S, Tsunematsu Y, Matsushita T, Hara K, Hashimoto H, Tang Y, Watanabe K.

Biochemistry. 2019 Sep 24;58(38):3933-3937. doi: 10.1021/acs.biochem.9b00702. Epub 2019 Sep 11.


Posterior occluding pairs of teeth or dentures and 1-year mortality in nursing home residents in Japan.

Dewake N, Hashimoto H, Nonoyama T, Nonoyama K, Shimazaki Y.

J Oral Rehabil. 2019 Sep 3. doi: 10.1111/joor.12883. [Epub ahead of print]


Definitive evidence of the presence of 24-methylenecycloartanyl ferulate and 24-methylenecycloartanyl caffeate in barley.

Ito J, Sawada K, Ogura Y, Xinyi F, Rahmania H, Mohri T, Kohyama N, Kwon E, Eitsuka T, Hashimoto H, Kuwahara S, Miyazawa T, Nakagawa K.

Sci Rep. 2019 Aug 29;9(1):12572. doi: 10.1038/s41598-019-48985-6.


Social influence of e-cigarette smoking prevalence on smoking behaviours among high-school teenagers: Microsimulation experiments.

Chao D, Hashimoto H, Kondo N.

PLoS One. 2019 Aug 29;14(8):e0221557. doi: 10.1371/journal.pone.0221557. eCollection 2019.


Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors.

Yokoyama H, Sawada JI, Sato K, Ogo N, Kamei N, Ishikawa Y, Hara K, Asai A, Hashimoto H.

ACS Omega. 2018 Sep 28;3(9):12284-12294. doi: 10.1021/acsomega.8b00778. eCollection 2018 Sep 30.


The efficacy of acute normovolemic hemodilution for preventing perioperative allogeneic blood transfusion in gynecological cancer patients.

Saito J, Masui K, Noguchi S, Nakai K, Tamai Y, Midorikawa Y, Kinoshita H, Mikami N, Kitayama M, Hashimoto H, Hirota K.

J Clin Anesth. 2019 Aug 20;60:42-43. doi: 10.1016/j.jclinane.2019.08.025. [Epub ahead of print] No abstract available.


Optimization of the method for analyzing endocytosis of fluorescently tagged molecules: Impact of incubation in the cell culture medium and cell surface wash with glycine-hydrochloric acid buffer.

Kamei N, Yamamoto S, Hashimoto H, Nishii M, Miyaura M, Tomada K, Nakase I, Takeda-Morishita M.

J Control Release. 2019 Sep 28;310:127-140. doi: 10.1016/j.jconrel.2019.08.020. Epub 2019 Aug 21.


Kinetic Stabilization of Carbazole Nitroxides by Inclusion in a Macrocage and Their Electron Spin Resonance Characterization.

Hashimoto H, Inagaki Y, Momma H, Kwon E, Setaka W.

J Org Chem. 2019 Sep 20;84(18):11783-11789. doi: 10.1021/acs.joc.9b01686. Epub 2019 Sep 6.


Interaction between cancer cells and cancer-associated fibroblasts after cisplatin treatment promotes cancer cell regrowth.

Hisamitsu S, Miyashita T, Hashimoto H, Neri S, Sugano M, Nakamura H, Yamazaki S, Ochiai A, Goto K, Tsuboi M, Ishii G.

Hum Cell. 2019 Oct;32(4):453-464. doi: 10.1007/s13577-019-00275-z. Epub 2019 Aug 22.


Safety and effectiveness of reduced-dose apixaban in Japanese patients with nonvalvular atrial fibrillation in clinical practice: A sub-analysis of the STANDARD study.

Inoue H, Umeyama M, Yamada T, Hashimoto H, Komoto A, Yasaka M.

J Cardiol. 2019 Aug 14. pii: S0914-5087(19)30223-0. doi: 10.1016/j.jjcc.2019.07.007. [Epub ahead of print]


Effects of astaxanthin on VEGF level and antioxidation in human aqueous humor: difference by sex.

Hashimoto H, Arai K, Takahashi J, Chikuda M.

J Clin Biochem Nutr. 2019 Jul;65(1):47-51. doi: 10.3164/jcbn.18-110. Epub 2019 Apr 18.


Performance of five ultrasonic transducers modified for efficient atomization.

Matsuura H, Furukawa H, Tanikawa T, Hashimoto H.

J Acoust Soc Am. 2019 Jul;146(1):626. doi: 10.1121/1.5118241.


Intensity-modulated radiation therapy using TomoDirect for postoperative radiation of left-sided breast cancer including lymph node area: comparison with TomoHelical and three-dimensional conformal radiation therapy.

Takano S, Omura M, Suzuki R, Tayama Y, Matsui K, Hashimoto H, Hongo H, Nagata H, Tanaka K, Hata M, Inoue T.

J Radiat Res. 2019 Jul 31. pii: rrz052. doi: 10.1093/jrr/rrz052. [Epub ahead of print]


Adiponectin levels among individuals with varied employment status in Japan: a cross-sectional analysis of the J-SHINE study.

Amano H, Shirakawa Y, Hashimoto H.

Sci Rep. 2019 Jul 29;9(1):10936. doi: 10.1038/s41598-019-47448-2.


Development and validation of the Total Dyspnea Scale for Cancer Patients.

Hashimoto H, Kanda K.

Eur J Oncol Nurs. 2019 Aug;41:120-125. doi: 10.1016/j.ejon.2019.05.007. Epub 2019 Jun 3.


A cleanser formulated with Tris (hydroxymethyl) aminomethane and l-arginine significantly improves facial acne in male Thai subjects.

Kumtornrut C, Manabe SD, Navapongsiri M, Okutani Y, Ikegaki S, Tanaka N, Hashimoto H, Songsantiphap C, Wantavornprasert K, Khamthara J, Takagi Y, Asawanonda P.

J Cosmet Dermatol. 2019 Jul 26. doi: 10.1111/jocd.13087. [Epub ahead of print]


Secretion of high amounts of hepatocyte growth factor is a characteristic feature of cancer-associated fibroblasts with EGFR-TKI resistance-promoting phenotype: A study of 18 cases of cancer-associated fibroblasts.

Suzuki E, Yamazaki S, Naito T, Hashimoto H, Okubo S, Udagawa H, Goto K, Tsuboi M, Ochiai A, Ishii G.

Pathol Int. 2019 Aug;69(8):472-480. doi: 10.1111/pin.12838. Epub 2019 Jul 24.


Associations of social relationships with curative and preventive dental care use among young and middle-aged adults: Evidence from a population-based study in Japan.

Murakami K, Aida J, Hashimoto H.

Community Dent Oral Epidemiol. 2019 Oct;47(5):389-397. doi: 10.1111/cdoe.12487. Epub 2019 Jul 23.


Substrate Affinity and Specificity of the ScSth1p Bromodomain Are Fine-Tuned for Versatile Histone Recognition.

Blus BJ, Hashimoto H, Seo HS, Krolak A, Debler EW.

Structure. 2019 Sep 3;27(9):1460-1468.e3. doi: 10.1016/j.str.2019.06.009. Epub 2019 Jul 18.


(R)-ketamine induces a greater increase in prefrontal 5-HT release than (S)-ketamine and ketamine metabolites via an AMPA receptor-independent mechanism.

Ago Y, Tanabe W, Higuchi M, Tsukada S, Tanaka T, Yamaguchi T, Igarashi H, Yokoyama R, Seiriki K, Kasai A, Nakazawa T, Nakagawa S, Hashimoto K, Hashimoto H.

Int J Neuropsychopharmacol. 2019 Jul 21. pii: pyz041. doi: 10.1093/ijnp/pyz041. [Epub ahead of print]


Organoid culture containing cancer cells and stromal cells reveals that podoplanin-positive cancer-associated fibroblasts enhance proliferation of lung cancer cells.

Nakamura H, Sugano M, Miyashita T, Hashimoto H, Ochiai A, Suzuki K, Tsuboi M, Ishii G.

Lung Cancer. 2019 Aug;134:100-107. doi: 10.1016/j.lungcan.2019.04.007. Epub 2019 Apr 8.


Association of extremely high levels of high-density lipoprotein cholesterol with endothelial dysfunction in men.

Takaeko Y, Matsui S, Kajikawa M, Maruhashi T, Kishimoto S, Hashimoto H, Kihara Y, Hida E, Chayama K, Goto C, Aibara Y, Yusoff FM, Noma K, Nakashima A, Higashi Y.

J Clin Lipidol. 2019 Jul - Aug;13(4):664-672.e1. doi: 10.1016/j.jacl.2019.06.004. Epub 2019 Jun 20.


Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study.

Kajikawa M, Maruhashi T, Hidaka T, Matsui S, Hashimoto H, Takaeko Y, Nakano Y, Kurisu S, Kihara Y, Yusoff FM, Kishimoto S, Chayama K, Goto C, Noma K, Nakashima A, Hiro T, Hirayama A, Shiina K, Tomiyama H, Yagi S, Amano R, Yamada H, Sata M, Higashi Y.

Sci Rep. 2019 Jul 15;9(1):10206. doi: 10.1038/s41598-019-46726-3.


Safety and effectiveness of apixaban in Japanese patients with nonvalvular atrial fibrillation in clinical practice: A regulatory postmarketing surveillance, the STANDARD study.

Inoue H, Umeyama M, Yamada T, Hashimoto H, Komoto A, Yasaka M.

J Arrhythm. 2019 May 9;35(3):506-514. doi: 10.1002/joa3.12184. eCollection 2019 Jun.


Cycloartenyl Ferulate and β-Sitosteryl Ferulate - Steryl Ferulates of γ-Oryzanol - Suppress Intracellular Reactive Oxygen Species in Cell-based System.

Yasuda S, Sowa Y, Hashimoto H, Nakagami T, Tsuno T, Sakai T.

J Oleo Sci. 2019 Aug 1;68(8):765-768. doi: 10.5650/jos.ess19054. Epub 2019 Jul 10.


A case report of thin basement membrane nephropathy accompanied by sporadic glomerulocystic kidney disease.

Hashimoto H, Ohashi N, Tsuji N, Naito Y, Isobe S, Fujikura T, Tsuji T, Kato A, Nozu K, Iijima K, Yasuda H.

BMC Nephrol. 2019 Jul 9;20(1):248. doi: 10.1186/s12882-019-1451-6.


Isolation of an Equine Foamy Virus and Sero-Epidemiology of the Viral Infection in Horses in Japan.

Kirisawa R, Toishi Y, Hashimoto H, Tsunoda N.

Viruses. 2019 Jul 5;11(7). pii: E613. doi: 10.3390/v11070613.


Association of IFNG gene methylation in peripheral blood cells with the development and prognosis of autoimmune thyroid diseases.

Hashimoto H, Watanabe M, Inoue N, Hirai N, Haga E, Kinoshita R, Hidaka Y, Iwatani Y.

Cytokine. 2019 Nov;123:154770. doi: 10.1016/j.cyto.2019.154770. Epub 2019 Jul 3.


Multicentre, open label, randomised controlled trial comparing intermittent versus daily treatment for non-cavitary nodular/bronchiectatic Mycobacterium avium complex lung disease with rifampicin, ethambutol and clarithromycin (iREC): study protocol.

Nakagawa T, Hashimoto H, Yagi M, Kogure Y, Sekimizu M, Saito AM, Ogawa K, Inoue Y.

BMJ Open Respir Res. 2019 May 30;6(1):e000434. doi: 10.1136/bmjresp-2019-000434. eCollection 2019.


Modeling of psychiatric disorders using induced pluripotent stem cell-related technologies.

Nakazawa T, Hashimoto R, Takuma K, Hashimoto H.

J Pharmacol Sci. 2019 Aug;140(4):321-324. doi: 10.1016/j.jphs.2019.06.002. Epub 2019 Jun 15. Review.


Preclinical Pharmacokinetic and Safety Studies of Copper-Diacetyl-Bis(N4-Methylthiosemicarbazone) (Cu-ATSM): Translational Studies for Internal Radiotherapy.

Matsumoto H, Yoshii Y, Baden A, Kaneko E, Hashimoto H, Suzuki H, Kawamura K, Zhang MR, Higashi T, Kurihara H.

Transl Oncol. 2019 Sep;12(9):1206-1212. doi: 10.1016/j.tranon.2019.05.017. Epub 2019 Jun 25.


A New Method to Quantify Concentration of Microbubbles in Attenuating Media Using Bubble Destruction Curve Analysis of the Contrast-Enhanced Ultrasound.

Kamiyama N, Wakui N, Oguri T, Hashimoto H, Kanayama Y, Nagai H.

Ultrasound Med Biol. 2019 Sep;45(9):2485-2492. doi: 10.1016/j.ultrasmedbio.2019.05.027. Epub 2019 Jun 22.


Cerebral amyloid-β-related angiitis without cerebral microbleeds in a patient with subarachnoid hemorrhage.

Nakaya M, Hashimoto H, Usui G, Sawada K, Shirouzu I, Oshima A, Okubo S, Yamada H, Morikawa T.

Cardiovasc Pathol. 2019 Sep - Oct;42:36-40. doi: 10.1016/j.carpath.2019.05.004. Epub 2019 May 25.


Structural basis of specific DNA binding by the transcription factor ZBTB24.

Ren R, Hardikar S, Horton JR, Lu Y, Zeng Y, Singh AK, Lin K, Coletta LD, Shen J, Lin Kong CS, Hashimoto H, Zhang X, Chen T, Cheng X.

Nucleic Acids Res. 2019 Sep 19;47(16):8388-8398. doi: 10.1093/nar/gkz557.


Psychiatric-disorder-related behavioral phenotypes and cortical hyperactivity in a mouse model of 3q29 deletion syndrome.

Baba M, Yokoyama K, Seiriki K, Naka Y, Matsumura K, Kondo M, Yamamoto K, Hayashida M, Kasai A, Ago Y, Nagayasu K, Hayata-Takano A, Takahashi A, Yamaguchi S, Mori D, Ozaki N, Yamamoto T, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T.

Neuropsychopharmacology. 2019 Nov;44(12):2125-2135. doi: 10.1038/s41386-019-0441-5. Epub 2019 Jun 19.


Intrahepatic Carcinosarcoma With Cholangiocarcinoma Elements and Prominent Bile Duct Spread.

Usui G, Hashimoto H, Kusakabe M, Shirota G, Sugiura Y, Fujita Y, Satou S, Harihara Y, Horiuchi H, Morikawa T.

Int J Surg Pathol. 2019 Jun 17:1066896919855766. doi: 10.1177/1066896919855766. [Epub ahead of print]


The impact of sirolimus therapy on lesion size, clinical symptoms, and quality of life of patients with lymphatic anomalies.

Ozeki M, Nozawa A, Yasue S, Endo S, Asada R, Hashimoto H, Fukao T.

Orphanet J Rare Dis. 2019 Jun 13;14(1):141. doi: 10.1186/s13023-019-1118-1.


The effect of coronal prosthetic alignment changes on socket reaction moments, spatiotemporal parameters, and perception of alignment during gait in individuals with transtibial amputation.

Hashimoto H, Kobayashi T, Gao F, Kataoka M, Okuda K.

J Rehabil Assist Technol Eng. 2018 Nov 18;5:2055668318795402. doi: 10.1177/2055668318795402. eCollection 2018 Jan-Dec.


[Whole-brain activity mapping at single-cell resolution].

Kasai A, Seiriki K, Hashimoto H.

Nihon Yakurigaku Zasshi. 2019;153(6):278-283. doi: 10.1254/fpj.153.278. Review. Japanese.


Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report.

Usui G, Hashimoto H, Sugiura Y, Nishi Y, Kusakabe M, Horiuchi H, Okubo S, Morikawa T.

Intern Med. 2019 Oct 1;58(19):2851-2855. doi: 10.2169/internalmedicine.2857-19. Epub 2019 Jun 7.


Hemophagocytic syndrome with acute kidney injury accompanied by erythrophagocytic macrophages in the tubular lumen.

Hashimoto H, Sugiura T, Matsushima H.

CEN Case Rep. 2019 Jun 4. doi: 10.1007/s13730-019-00402-7. [Epub ahead of print]

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