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Items: 1 to 50 of 293

1.

Toxicological evaluation of carcinogenicity of the pyrethroid imiprothrin in rats and mice.

Yamada T, Asano H, Miyata K, Rhomberg LR, Haseman JK, Greaves P, Greim H, Berry C, Cohen SM.

Regul Toxicol Pharmacol. 2019 Jul;105:1-14. doi: 10.1016/j.yrtph.2019.03.012. Epub 2019 Mar 21.

PMID:
30905765
2.

A critical examination of the mode of action of quinacrine in the reproductive tract in a 2-year rat cancer bioassay and its implications for human clinical use.

Haseman JK, Growe RG, Zeiger E, McConnell EE, Luster MI, Lippes J.

Regul Toxicol Pharmacol. 2015 Apr;71(3):371-8. doi: 10.1016/j.yrtph.2015.02.006. Epub 2015 Feb 10.

4.

Evaluating consistency in the interpretation of NTP rodent cancer bioassays: an examination of mouse lung tumor effects in the 4-MEI study.

Haseman JK.

Regul Toxicol Pharmacol. 2013 Jun;66(1):109-15. doi: 10.1016/j.yrtph.2013.03.009. Epub 2013 Mar 29.

PMID:
23545072
5.

Bacterial membrane disrupting dodecapeptide SC4 improves survival of mice challenged with Pseudomonas aeruginosa.

Dings RP, Haseman JR, Leslie DB, Luong M, Dunn DL, Mayo KH.

Biochim Biophys Acta. 2013 Jun;1830(6):3454-7. doi: 10.1016/j.bbagen.2013.02.002. Epub 2013 Feb 9.

6.

Using fewer animals to identify chemical eye hazards: revised criteria necessary to maintain equivalent hazard classification.

Haseman JK, Allen DG, Lipscomb EA, Truax JF, Stokes WS.

Regul Toxicol Pharmacol. 2011 Oct;61(1):98-104. doi: 10.1016/j.yrtph.2011.06.006. Epub 2011 Jul 1.

7.

Safety assessment of allergic contact dermatitis hazards: an analysis supporting reduced animal use for the murine local lymph node assay.

Haseman JK, Strickland J, Allen D, Salicru E, Paris M, Tice RR, Stokes WS.

Regul Toxicol Pharmacol. 2011 Feb;59(1):191-6. doi: 10.1016/j.yrtph.2010.10.004. Epub 2010 Oct 23.

8.

Investigation of the low-dose response in the in vivo induction of micronuclei and adducts by acrylamide.

Zeiger E, Recio L, Fennell TR, Haseman JK, Snyder RW, Friedman M.

Toxicol Sci. 2009 Jan;107(1):247-57. doi: 10.1093/toxsci/kfn214. Epub 2008 Oct 17.

PMID:
18931380
9.

Analysis of nonlinear regression models: a cautionary note.

Peddada SD, Haseman JK.

Dose Response. 2006 May 1;3(3):342-52. doi: 10.2203/dose-response.003.03.005.

10.

Probing structure-activity relationships in bactericidal peptide betapep-25.

Dings RP, Haseman JR, Mayo KH.

Biochem J. 2008 Aug 15;414(1):143-50. doi: 10.1042/BJ20080506.

PMID:
18489259
11.

Association of race, age and body mass index with gross pathology of uterine fibroids.

Moore AB, Flake GP, Swartz CD, Heartwell G, Cousins D, Haseman JK, Kissling GE, Sidawy MK, Dixon D.

J Reprod Med. 2008 Feb;53(2):90-6.

PMID:
18357799
12.

Variations in phytoestrogen content between different mill dates of the same diet produces significant differences in the time of vaginal opening in CD-1 mice and F344 rats but not in CD Sprague-Dawley rats.

Thigpen JE, Setchell KD, Padilla-Banks E, Haseman JK, Saunders HE, Caviness GF, Kissling GE, Grant MG, Forsythe DB.

Environ Health Perspect. 2007 Dec;115(12):1717-26.

13.

A review of large granular lymphocytic leukemia in Fischer 344 rats as an initial step toward evaluating the implication of the endpoint to human cancer risk assessment.

Thomas J, Haseman JK, Goodman JI, Ward JM, Loughran TP Jr, Spencer PJ.

Toxicol Sci. 2007 Sep;99(1):3-19. Epub 2007 May 22. Review.

PMID:
17522071
14.

Topomimetics of amphipathic beta-sheet and helix-forming bactericidal peptides neutralize lipopolysaccharide endotoxins.

Chen X, Dings RP, Nesmelova I, Debbert S, Haseman JR, Maxwell J, Hoye TR, Mayo KH.

J Med Chem. 2006 Dec 28;49(26):7754-65.

15.

Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program.

Brix AE, Nyska A, Haseman JK, Sells DM, Jokinen MP, Walker NJ.

Toxicol Pathol. 2005;33(4):477-83.

PMID:
16036865
16.

Synchronous global assessment of gene and protein expression in colorectal cancer progression.

Kwong KY, Bloom GC, Yang I, Boulware D, Coppola D, Haseman J, Chen E, McGrath A, Makusky AJ, Taylor J, Steiner S, Zhou J, Yeatman TJ, Quackenbush J.

Genomics. 2005 Aug;86(2):142-58.

PMID:
15951154
17.

Upregulation of estrogen receptor expression in the uterus of ovariectomized B6C3F1 mice and Ishikawa cells treated with bromoethane.

Aoyama H, Couse JF, Hewitt SC, Haseman JK, He H, Zheng X, Majstoravich S, Korach KS, Dixon D.

Toxicol Appl Pharmacol. 2005 Dec 15;209(3):226-35.

PMID:
15922381
18.

Dose-additive carcinogenicity of a defined mixture of "dioxin-like compounds".

Walker NJ, Crockett PW, Nyska A, Brix AE, Jokinen MP, Sells DM, Hailey JR, Easterling M, Haseman JK, Yin M, Wyde ME, Bucher JR, Portier CJ.

Environ Health Perspect. 2005 Jan;113(1):43-8.

19.

Gingival carcinogenicity in female Harlan Sprague-Dawley rats following two-year oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds.

Yoshizawa K, Walker NJ, Jokinen MP, Brix AE, Sells DM, Marsh T, Wyde ME, Orzech D, Haseman JK, Nyska A.

Toxicol Sci. 2005 Jan;83(1):64-77. Epub 2004 Oct 27. Erratum in: Toxicol Sci. 2005 Feb;83(2):405-6.

PMID:
15509667
20.

Selecting the appropriate rodent diet for endocrine disruptor research and testing studies.

Thigpen JE, Setchell KD, Saunders HE, Haseman JK, Grant MG, Forsythe DB.

ILAR J. 2004;45(4):401-16. Review.

PMID:
15454679
21.

Toxicology and carcinogenesis studies of dipropylene glycol in rats and mice.

Hooth MJ, Herbert RA, Haseman JK, Orzech DP, Johnson JD, Bucher JR.

Toxicology. 2004 Nov 15;204(2-3):123-40.

PMID:
15388239
22.

Toxicology and carcinogenesis studies of microencapsulated trans-cinnamaldehyde in rats and mice.

Hooth MJ, Sills RC, Burka LT, Haseman JK, Witt KL, Orzech DP, Fuciarelli AF, Graves SW, Johnson JD, Bucher JR.

Food Chem Toxicol. 2004 Nov;42(11):1757-68.

PMID:
15350673
23.
24.

Association of liver hemangiosarcoma and secondary iron overload in B6C3F1 mice--the National Toxicology Program experience.

Nyska A, Haseman JK, Kohen R, Maronpot RR.

Toxicol Pathol. 2004 Mar-Apr;32(2):222-8.

PMID:
15200160
25.

Exocrine pancreatic pathology in female Harlan Sprague-Dawley rats after chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds.

Nyska A, Jokinen MP, Brix AE, Sells DM, Wyde ME, Orzech D, Haseman JK, Flake G, Walker NJ.

Environ Health Perspect. 2004 Jun;112(8):903-9.

26.

Promotion of peptide antimicrobial activity by fatty acid conjugation.

Chu-Kung AF, Bozzelli KN, Lockwood NA, Haseman JR, Mayo KH, Tirrell MV.

Bioconjug Chem. 2004 May-Jun;15(3):530-5.

PMID:
15149180
27.

Inhalation toxicology and carcinogenesis studies of propylene glycol mono-t-butyl ether in rats and mice.

Doi AM, Roycroft JH, Herbert RA, Haseman JK, Hailey JR, Chou BJ, Dill JA, Grumbein SL, Miller RA, Renne RA, Bucher JR.

Toxicology. 2004 Jun 1;199(1):1-22.

PMID:
15125995
28.

Developmental exposure to diethylstilbestrol (DES) alters uterine response to estrogens in prepubescent mice: low versus high dose effects.

Newbold RR, Jefferson WN, Padilla-Banks E, Haseman J.

Reprod Toxicol. 2004 May;18(3):399-406.

PMID:
15082075
29.
30.

Dietary phytoestrogens accelerate the time of vaginal opening in immature CD-1 mice.

Thigpen JE, Haseman JK, Saunders HE, Setchell KD, Grant MG, Forsythe DB.

Comp Med. 2003 Dec;53(6):607-15.

PMID:
14727808
31.

Follicular epithelial cell hypertrophy induced by chronic oral administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley rats.

Tani Y, Maronpot RR, Foley JF, Haseman JK, Walker NJ, Nyska A.

Toxicol Pathol. 2004 Jan-Feb;32(1):41-9.

PMID:
14713547
32.
33.

Genetic alterations in the Catnb gene but not the H-ras gene in hepatocellular neoplasms and hepatoblastomas of B6C3F(1) mice following exposure to diethanolamine for 2 years.

Hayashi SM, Ton TV, Hong HH, Irwin RD, Haseman JK, Devereux TR, Sills RC.

Chem Biol Interact. 2003 Dec 15;146(3):251-61.

PMID:
14642737
34.
35.
36.

Design of a partial peptide mimetic of anginex with antiangiogenic and anticancer activity.

Mayo KH, Dings RP, Flader C, Nesmelova I, Hargittai B, van der Schaft DW, van Eijk LI, Walek D, Haseman J, Hoye TR, Griffioen AW.

J Biol Chem. 2003 Nov 14;278(46):45746-52. Epub 2003 Aug 28.

37.

Toxicity and carcinogenicity of riddelliine in rats and mice.

Chan PC, Haseman JK, Prejean JD, Nyska A.

Toxicol Lett. 2003 Oct 15;144(3):295-311.

PMID:
12927348
38.

Photocarcinogenesis in the Tg.AC mouse: lomefloxacin and 8-methoxypsoralen.

Chignell CF, Haseman JK, Sik RH, Tennant RW, Trempus CS.

Photochem Photobiol. 2003 Jan;77(1):77-80.

PMID:
12856886
39.

The effect on sperm production in adult Sprague-Dawley rats exposed by gavage to bisphenol A between postnatal days 91-97.

Ashby J, Tinwell H, Lefevre PA, Joiner R, Haseman J.

Toxicol Sci. 2003 Jul;74(1):129-38. Epub 2003 May 28.

PMID:
12773777
40.

Carcinogenicity of inhaled vanadium pentoxide in F344/N rats and B6C3F1 mice.

Ress NB, Chou BJ, Renne RA, Dill JA, Miller RA, Roycroft JH, Hailey JR, Haseman JK, Bucher JR.

Toxicol Sci. 2003 Aug;74(2):287-96. Epub 2003 May 28.

PMID:
12773761
41.

A comparative immunohistochemical study of spontaneous and chemically induced pheochromocytomas in B6C3F1 mice.

Hill GD, Pace V, Persohn E, Bresser C, Haseman JK, Tischler AS, Nyska A.

Endocr Pathol. 2003 Spring;14(1):81-91.

PMID:
12746566
42.

Beta-sheet is the bioactive conformation of the anti-angiogenic anginex peptide.

Dings RP, Arroyo MM, Lockwood NA, van Eijk LI, Haseman JR, Griffioen AW, Mayo KH.

Biochem J. 2003 Jul 1;373(Pt 1):281-8.

43.

Anti-tumor activity of the novel angiogenesis inhibitor anginex.

Dings RP, van der Schaft DW, Hargittai B, Haseman J, Griffioen AW, Mayo KH.

Cancer Lett. 2003 May 8;194(1):55-66.

PMID:
12706859
44.

The role of transgenic mouse models in carcinogen identification.

Pritchard JB, French JE, Davis BJ, Haseman JK.

Environ Health Perspect. 2003 Apr;111(4):444-54. Review.

45.

Slowing tumorigenic progression in TRAMP mice and prostatic carcinoma cell lines using natural anti-oxidant from spinach, NAO--a comparative study of three anti-oxidants.

Nyska A, Suttie A, Bakshi S, Lomnitski L, Grossman S, Bergman M, Ben-Shaul V, Crocket P, Haseman JK, Moser G, Goldsworthy TL, Maronpot RR.

Toxicol Pathol. 2003 Jan-Feb;31(1):39-51.

PMID:
12597448
46.

A grading scheme for the assessment of proliferative lesions of the mouse prostate in the TRAMP model.

Suttie A, Nyska A, Haseman JK, Moser GJ, Hackett TR, Goldsworthy TL.

Toxicol Pathol. 2003 Jan-Feb;31(1):31-8.

PMID:
12597447
47.

Toxicology and carcinogenesis studies of microencapsulated citral in rats and mice.

Ress NB, Hailey JR, Maronpot RR, Bucher JR, Travlos GS, Haseman JK, Orzech DP, Johnson JD, Hejtmancik MR.

Toxicol Sci. 2003 Feb;71(2):198-206.

PMID:
12563105
48.

Dietary factors affecting uterine weights of immature CD-1 mice used in uterotrophic bioassays.

Thigpen JE, Haseman JK, Saunders H, Locklear J, Caviness G, Grant M, Forsythe D.

Cancer Detect Prev. 2002;26(5):381-93.

PMID:
12518869
49.

The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats.

Seely JC, Haseman JK, Nyska A, Wolf DC, Everitt JI, Hailey JR.

Toxicol Pathol. 2002 Nov-Dec;30(6):681-6.

PMID:
12512869
50.

Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins.

Bebenek A, Carver GT, Dressman HK, Kadyrov FA, Haseman JK, Petrov V, Konigsberg WH, Karam JD, Drake JW.

Genetics. 2002 Nov;162(3):1003-18.

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