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Items: 42


In vivo and in silico study of allicin as a stroke prevention: PS074.

Janardhana A, Al Hasan NM, Prawira EN.

Porto Biomed J. 2017 Sep-Oct;2(5):204. doi: 10.1016/j.pbj.2017.07.069. Epub 2017 Sep 1. No abstract available.


ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly.

Hayward D, Kouznetsova VL, Pierson HE, Hasan NM, Guzman ER, Tsigelny IF, Lutsenko S.

J Biol Chem. 2019 Sep 27;294(39):14454-14466. doi: 10.1074/jbc.RA119.008231. Epub 2019 Jul 23.


Promoter methylation of ADAMTS1 and BNC1 as potential biomarkers for early detection of pancreatic cancer in blood.

Eissa MAL, Lerner L, Abdelfatah E, Shankar N, Canner JK, Hasan NM, Yaghoobi V, Huang B, Kerner Z, Takaesu F, Wolfgang C, Kwak R, Ruiz M, Tam M, Pisanic TR 2nd, Iacobuzio-Donahue CA, Hruban RH, He J, Wang TH, Wood LD, Sharma A, Ahuja N.

Clin Epigenetics. 2019 Apr 5;11(1):59. doi: 10.1186/s13148-019-0650-0.


Human copper transporter ATP7B (Wilson disease protein) forms stable dimers in vitro and in cells.

Jayakanthan S, Braiterman LT, Hasan NM, Unger VM, Lutsenko S.

J Biol Chem. 2017 Nov 17;292(46):18760-18774. doi: 10.1074/jbc.M117.807263. Epub 2017 Aug 24.


The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology.

Yu H, Hasan NM, In JG, Estes MK, Kovbasnjuk O, Zachos NC, Donowitz M.

Annu Rev Physiol. 2017 Feb 10;79:291-312. doi: 10.1146/annurev-physiol-021115-105211. Review.


Discovery of a Genetic Metabolic Cause for Mauriac Syndrome in Type 1 Diabetes.

MacDonald MJ, Hasan NM, Ansari IU, Longacre MJ, Kendrick MA, Stoker SW.

Diabetes. 2016 Jul;65(7):2051-9. doi: 10.2337/db16-0099. Epub 2016 Apr 5.


Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway.

Hatori Y, Yan Y, Schmidt K, Furukawa E, Hasan NM, Yang N, Liu CN, Sockanathan S, Lutsenko S.

Nat Commun. 2016 Feb 16;7:10640. doi: 10.1038/ncomms10640.


Mitochondrial malic enzyme 3 is important for insulin secretion in pancreatic β-cells.

Hasan NM, Longacre MJ, Stoker SW, Kendrick MA, MacDonald MJ.

Mol Endocrinol. 2015 Mar;29(3):396-410. doi: 10.1210/me.2014-1249. Epub 2015 Jan 16.


Role of medium-chain fatty acids in the emulsification mechanistics of self-micro-emulsifying lipid formulations.

Hasan NM.

Saudi Pharm J. 2014 Dec;22(6):580-90. doi: 10.1016/j.jsps.2014.02.005. Epub 2014 Feb 25.


Genome-wide RNAi ionomics screen reveals new genes and regulation of human trace element metabolism.

Malinouski M, Hasan NM, Zhang Y, Seravalli J, Lin J, Avanesov A, Lutsenko S, Gladyshev VN.

Nat Commun. 2014;5:3301. doi: 10.1038/ncomms4301.


Knockdown of both mitochondrial isocitrate dehydrogenase enzymes in pancreatic beta cells inhibits insulin secretion.

MacDonald MJ, Brown LJ, Longacre MJ, Stoker SW, Kendrick MA, Hasan NM.

Biochim Biophys Acta. 2013 Nov;1830(11):5104-11. doi: 10.1016/j.bbagen.2013.07.013. Epub 2013 Jul 20. Erratum in: Biochim Biophys Acta. 2013. doi: 10.1016/j.bbagen.2013.09.024. Hasan, Noaman M [added]. Biochim Biophys Acta. 2015 Jun;1850(6):1343.


Gas-phase synthesis of singly and multiply charged polyoxovanadate anions employing electrospray ionization and collision induced dissociation.

Al Hasan NM, Johnson GE, Laskin J.

J Am Soc Mass Spectrom. 2013 Sep;24(9):1385-95. doi: 10.1007/s13361-013-0683-0. Epub 2013 Jul 2.


Knockdown of pyruvate carboxylase or fatty acid synthase lowers numerous lipids and glucose-stimulated insulin release in insulinoma cells.

MacDonald MJ, Hasan NM, Dobrzyn A, Stoker SW, Ntambi JM, Liu X, Sampath H.

Arch Biochem Biophys. 2013 Apr 1;532(1):23-31. doi: 10.1016/ Epub 2013 Jan 25.


Regulation of copper transporters in human cells.

Hasan NM, Lutsenko S.

Curr Top Membr. 2012;69:137-61. doi: 10.1016/B978-0-12-394390-3.00006-9. Review.


Molecular events initiating exit of a copper-transporting ATPase ATP7B from the trans-Golgi network.

Hasan NM, Gupta A, Polishchuk E, Yu CH, Polishchuk R, Dmitriev OY, Lutsenko S.

J Biol Chem. 2012 Oct 19;287(43):36041-50. doi: 10.1074/jbc.M112.370403. Epub 2012 Aug 16.


Functional partnership of the copper export machinery and glutathione balance in human cells.

Hatori Y, Clasen S, Hasan NM, Barry AN, Lutsenko S.

J Biol Chem. 2012 Aug 3;287(32):26678-87. doi: 10.1074/jbc.M112.381178. Epub 2012 May 30.


Amelioration of Murine Schistosoma mansoni Induced Liver Fibrosis by Mesenchymal Stem Cells.

Abdel Aziz M, Atta H, Roshdy N, Rashed L, Sabry D, Hassouna A, Aboul Fotouh G, Hasan N, Younis R, Chowdhury J.

J Stem Cells Regen Med. 2012 Apr 14;8(1):28-34. eCollection 2012.


Sphingosine kinase 1 knockdown reduces insulin synthesis and secretion in a rat insulinoma cell line.

Hasan NM, Longacre MJ, Stoker SW, Kendrick MA, Druckenbrod NR, Laychock SG, Mastrandrea LD, MacDonald MJ.

Arch Biochem Biophys. 2012 Feb 1;518(1):23-30. doi: 10.1016/ Epub 2011 Dec 4.


Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets.

MacDonald MJ, Longacre MJ, Stoker SW, Kendrick M, Thonpho A, Brown LJ, Hasan NM, Jitrapakdee S, Fukao T, Hanson MS, Fernandez LA, Odorico J.

J Biol Chem. 2011 May 27;286(21):18383-96. doi: 10.1074/jbc.M111.241182. Epub 2011 Mar 22.


Lower succinyl-CoA:3-ketoacid-CoA transferase (SCOT) and ATP citrate lyase in pancreatic islets of a rat model of type 2 diabetes: knockdown of SCOT inhibits insulin release in rat insulinoma cells.

Hasan NM, Longacre MJ, Seed Ahmed M, Kendrick MA, Gu H, Ostenson CG, Fukao T, MacDonald MJ.

Arch Biochem Biophys. 2010 Jul;499(1-2):62-8. doi: 10.1016/ Epub 2010 May 9.


Genetic association of the neuropilin-1 gene with type 1 diabetes in children: Neuropilin-1 expression in pancreatic islets.

Hasan NM, Kendrick MA, Druckenbrod NR, Huelsmeyer MK, Warner TF, MacDonald MJ.

Diabetes Res Clin Pract. 2010 Mar;87(3):e29-32. doi: 10.1016/j.diabres.2009.12.016. Epub 2010 Jan 6.


Chronic reduction of the cytosolic or mitochondrial NAD(P)-malic enzyme does not affect insulin secretion in a rat insulinoma cell line.

Brown LJ, Longacre MJ, Hasan NM, Kendrick MA, Stoker SW, Macdonald MJ.

J Biol Chem. 2009 Dec 18;284(51):35359-67. doi: 10.1074/jbc.M109.040394.


The use of a neutron backscatter technique for in-situ water measurement in paper-recycling industry.

Hasan NM, Zain RM, Abdul Rahman MF, Mustapha I.

Appl Radiat Isot. 2009 Jul-Aug;67(7-8):1239-43. doi: 10.1016/j.apradiso.2009.02.020. Epub 2009 Feb 20.


Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase.

Hasan NM, Longacre MJ, Stoker SW, Boonsaen T, Jitrapakdee S, Kendrick MA, Wallace JC, MacDonald MJ.

J Biol Chem. 2008 Oct 17;283(42):28048-59. doi: 10.1074/jbc.M804170200. Epub 2008 Aug 12.


Studies with leucine, beta-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion.

Macdonald MJ, Hasan NM, Longacre MJ.

Biochim Biophys Acta. 2008 Jul-Aug;1780(7-8):966-72. doi: 10.1016/j.bbagen.2008.03.017. Epub 2008 Apr 4.


Anaplerosis from glucose, alpha-ketoisocaproate, and pyruvate in pancreatic islets, INS-1 cells and liver mitochondria.

MacDonald MJ, Stoker SW, Hasan NM.

Mol Cell Biochem. 2008 Jun;313(1-2):195-202. doi: 10.1007/s11010-008-9757-x. Epub 2008 Apr 15.


Acetoacetate and beta-hydroxybutyrate in combination with other metabolites release insulin from INS-1 cells and provide clues about pathways in insulin secretion.

MacDonald MJ, Longacre MJ, Stoker SW, Brown LJ, Hasan NM, Kendrick MA.

Am J Physiol Cell Physiol. 2008 Feb;294(2):C442-50. Epub 2007 Dec 26.


Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cell.

MacDonald MJ, Smith AD 3rd, Hasan NM, Sabat G, Fahien LA.

J Biol Chem. 2007 Oct 19;282(42):30596-606. Epub 2007 Aug 27.


Therapeutic potential of bone marrow-derived mesenchymal stem cells on experimental liver fibrosis.

Abdel Aziz MT, Atta HM, Mahfouz S, Fouad HH, Roshdy NK, Ahmed HH, Rashed LA, Sabry D, Hassouna AA, Hasan NM.

Clin Biochem. 2007 Aug;40(12):893-9. Epub 2007 May 3.


Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion.

MacDonald MJ, Fahien LA, Brown LJ, Hasan NM, Buss JD, Kendrick MA.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E1-15. Review.


Citrate oscillates in liver and pancreatic beta cell mitochondria and in INS-1 insulinoma cells.

MacDonald MJ, Fahien LA, Buss JD, Hasan NM, Fallon MJ, Kendrick MA.

J Biol Chem. 2003 Dec 19;278(51):51894-900. Epub 2003 Sep 30.


Single-stranded conformational polymorphism analysis of the mitochondrial glycerol phosphate dehydrogenase gene in NIDDM.

MacDonald MJ, Brown LJ, Hasan NM, Stoffel M, Dills DG.

Diabetes. 1997 Oct;46(10):1660-1. No abstract available.


The Klaas Breur Lecture. Radiation, hypoxia and genetic stimulation: implications for future therapies.

Adams GE, Hasan NM, Joiner MC.

Radiother Oncol. 1997 Aug;44(2):101-9.


Xanthine oxidase/dehydrogenase activity in intact cultured cells (in situ analysis).

Hasan NM, Cundall RB, Adams GE.

Free Radic Res Commun. 1992;16(3):175-82.


Autonomous DNA binding domains of lambda integrase recognize two different sequence families.

Moitoso de Vargas L, Pargellis CA, Hasan NM, Bushman EW, Landy A.

Cell. 1988 Sep 23;54(7):923-9.


Oxazoles in organic chemistry. Synthesis of the antitumor agent ellipticine.

Kozikowski AP, Hasan NM.

J Org Chem. 1977 May 27;42(11):2039-40. No abstract available.


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