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Items: 1 to 50 of 82

1.

Secondary metabolite production and the safety of industrially important members of the Bacillus subtilis group.

Harwood CR, Mouillon JM, Pohl S, Arnau J.

FEMS Microbiol Rev. 2018 Jul 19. doi: 10.1093/femsre/fuy028. [Epub ahead of print]

PMID:
30053041
2.

Exploring the Nonconserved Sequence Space of Synthetic Expression Modules in Bacillus subtilis.

Sauer C, Ver Loren van Themaat E, Boender LGM, Groothuis D, Cruz R, Hamoen LW, Harwood CR, van Rij T.

ACS Synth Biol. 2018 Jul 20;7(7):1773-1784. doi: 10.1021/acssynbio.8b00110. Epub 2018 Jul 5.

PMID:
29939720
3.

Co-optimization of sponge-core bioreactors for removing total nitrogen and antibiotic resistance genes from domestic wastewater.

Jong MC, Su JQ, Bunce JT, Harwood CR, Snape JR, Zhu YG, Graham DW.

Sci Total Environ. 2018 Sep 1;634:1417-1423. doi: 10.1016/j.scitotenv.2018.04.044. Epub 2018 Apr 18.

PMID:
29710641
4.

Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement.

Borriss R, Danchin A, Harwood CR, Médigue C, Rocha EPC, Sekowska A, Vallenet D.

Microb Biotechnol. 2018 Jan;11(1):3-17. doi: 10.1111/1751-7915.13043.

5.

Extracellular Self-Assembly of Functional and Tunable Protein Conjugates from Bacillus subtilis.

Gilbert C, Howarth M, Harwood CR, Ellis T.

ACS Synth Biol. 2017 Jun 16;6(6):957-967. doi: 10.1021/acssynbio.6b00292. Epub 2017 Mar 7.

6.

The Identification of Intrinsic Chloramphenicol and Tetracycline Resistance Genes in Members of the Bacillus cereus Group (sensu lato).

Glenwright H, Pohl S, Navarro F, Miro E, Jiménez G, Blanch AR, Harwood CR.

Front Microbiol. 2017 Jan 4;7:2122. doi: 10.3389/fmicb.2016.02122. eCollection 2016.

7.

Effect of Genome Position on Heterologous Gene Expression in Bacillus subtilis: An Unbiased Analysis.

Sauer C, Syvertsson S, Bohorquez LC, Cruz R, Harwood CR, van Rij T, Hamoen LW.

ACS Synth Biol. 2016 Sep 16;5(9):942-7. doi: 10.1021/acssynbio.6b00065. Epub 2016 May 27.

PMID:
27197833
8.

Binase-like guanyl-preferring ribonucleases are new members of Bacillus PhoP regulon.

Ulyanova V, Vershinina V, Ilinskaya O, Harwood CR.

Microbiol Res. 2015 Jan;170:131-8. doi: 10.1016/j.micres.2014.08.005. Epub 2014 Aug 29.

9.

Proteomic analysis of Bacillus subtilis strains engineered for improved production of heterologous proteins.

Pohl S, Bhavsar G, Hulme J, Bloor AE, Misirli G, Leckenby MW, Radford DS, Smith W, Wipat A, Williamson ED, Harwood CR, Cranenburgh RM.

Proteomics. 2013 Nov;13(22):3298-308. doi: 10.1002/pmic.201300183. Epub 2013 Oct 27.

PMID:
24115457
10.

Extracytoplasmic proteases determining the cleavage and release of secreted proteins, lipoproteins, and membrane proteins in Bacillus subtilis.

Krishnappa L, Dreisbach A, Otto A, Goosens VJ, Cranenburgh RM, Harwood CR, Becher D, van Dijl JM.

J Proteome Res. 2013 Sep 6;12(9):4101-10. doi: 10.1021/pr400433h. Epub 2013 Aug 26.

PMID:
23937099
11.

Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.

Nicolas P, Mäder U, Dervyn E, Rochat T, Leduc A, Pigeonneau N, Bidnenko E, Marchadier E, Hoebeke M, Aymerich S, Becher D, Bisicchia P, Botella E, Delumeau O, Doherty G, Denham EL, Fogg MJ, Fromion V, Goelzer A, Hansen A, Härtig E, Harwood CR, Homuth G, Jarmer H, Jules M, Klipp E, Le Chat L, Lecointe F, Lewis P, Liebermeister W, March A, Mars RA, Nannapaneni P, Noone D, Pohl S, Rinn B, Rügheimer F, Sappa PK, Samson F, Schaffer M, Schwikowski B, Steil L, Stülke J, Wiegert T, Devine KM, Wilkinson AJ, van Dijl JM, Hecker M, Völker U, Bessières P, Noirot P.

Science. 2012 Mar 2;335(6072):1103-6. doi: 10.1126/science.1206848.

12.

Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism.

Buescher JM, Liebermeister W, Jules M, Uhr M, Muntel J, Botella E, Hessling B, Kleijn RJ, Le Chat L, Lecointe F, Mäder U, Nicolas P, Piersma S, Rügheimer F, Becher D, Bessieres P, Bidnenko E, Denham EL, Dervyn E, Devine KM, Doherty G, Drulhe S, Felicori L, Fogg MJ, Goelzer A, Hansen A, Harwood CR, Hecker M, Hubner S, Hultschig C, Jarmer H, Klipp E, Leduc A, Lewis P, Molina F, Noirot P, Peres S, Pigeonneau N, Pohl S, Rasmussen S, Rinn B, Schaffer M, Schnidder J, Schwikowski B, Van Dijl JM, Veiga P, Walsh S, Wilkinson AJ, Stelling J, Aymerich S, Sauer U.

Science. 2012 Mar 2;335(6072):1099-103. doi: 10.1126/science.1206871.

13.

Dissection of the network of interactions that links RNA processing with glycolysis in the Bacillus subtilis degradosome.

Newman JA, Hewitt L, Rodrigues C, Solovyova AS, Harwood CR, Lewis RJ.

J Mol Biol. 2012 Feb 10;416(1):121-36. doi: 10.1016/j.jmb.2011.12.024. Epub 2011 Dec 16.

PMID:
22198292
14.

Cellular iron distribution in Bacillus anthracis.

Tu WY, Pohl S, Gray J, Robinson NJ, Harwood CR, Waldron KJ.

J Bacteriol. 2012 Mar;194(5):932-40. doi: 10.1128/JB.06195-11. Epub 2011 Dec 16.

15.

Comparative analysis of the responses of related pathogenic and environmental bacteria to oxidative stress.

Tu WY, Pohl S, Summpunn P, Hering S, Kerstan S, Harwood CR.

Microbiology. 2012 Mar;158(Pt 3):636-47. doi: 10.1099/mic.0.057000-0. Epub 2011 Dec 15.

PMID:
22174384
16.

The iron-binding protein Dps2 confers peroxide stress resistance on Bacillus anthracis.

Tu WY, Pohl S, Gizynski K, Harwood CR.

J Bacteriol. 2012 Mar;194(5):925-31. doi: 10.1128/JB.06005-11. Epub 2011 Dec 9.

17.

Effect of sample thickness on the extracted near-infrared bulk optical properties of Bacillus subtilis in liquid culture.

Dzhongova E, Harwood CR, Thennadil SN.

Appl Spectrosc. 2011 Nov;65(11):1314-20. doi: 10.1366/11-06338.

PMID:
22054092
18.

SmaI restriction site-based multiplex PCR for typing of hospital- and community-acquired Staphylococcus aureus.

Al-Zahrani IA, Hamson C, Edge D, Collins J, Perry JD, Raza M, Gould K, Harwood CR.

J Clin Microbiol. 2011 Nov;49(11):3820-8. doi: 10.1128/JCM.00857-11. Epub 2011 Sep 21.

19.

Unusual, dual endo- and exonuclease activity in the degradosome explained by crystal structure analysis of RNase J1.

Newman JA, Hewitt L, Rodrigues C, Solovyova A, Harwood CR, Lewis RJ.

Structure. 2011 Sep 7;19(9):1241-51. doi: 10.1016/j.str.2011.06.017.

20.

Combined proteomic and transcriptomic analysis of the response of Bacillus anthracis to oxidative stress.

Pohl S, Tu WY, Aldridge PD, Gillespie C, Hahne H, Mäder U, Read TD, Harwood CR.

Proteomics. 2011 Aug;11(15):3036-55. doi: 10.1002/pmic.201100085. Epub 2011 Jul 4.

PMID:
21726052
21.

Environmental salinity determines the specificity and need for Tat-dependent secretion of the YwbN protein in Bacillus subtilis.

van der Ploeg R, Mäder U, Homuth G, Schaffer M, Denham EL, Monteferrante CG, Miethke M, Marahiel MA, Harwood CR, Winter T, Hecker M, Antelmann H, van Dijl JM.

PLoS One. 2011 Mar 30;6(3):e18140. doi: 10.1371/journal.pone.0018140.

22.

Report of an outbreak of CO2-dependent methicillin-resistant Staphylococcus aureus on a regional liver transplant unit.

Hamson C, Walton KE, Collins J, Wilson L, Perry JD, Al-Zahrani IA, Harwood CR.

J Antimicrob Chemother. 2011 May;66(5):1179-81. doi: 10.1093/jac/dkr055. Epub 2011 Feb 24. No abstract available.

PMID:
21393168
23.

Heterologous protein secretion by bacillus species from the cradle to the grave.

Pohl S, Harwood CR.

Adv Appl Microbiol. 2010;73:1-25. doi: 10.1016/S0065-2164(10)73001-X. Review.

PMID:
20800757
24.

Changes in the absorption and scattering properties in the near-infrared region during the growth of Bacillus subtilis in liquid culture.

Dzhongova E, Harwood CR, Thennadil SN.

Appl Spectrosc. 2009 Jan;63(1):25-32. doi: 10.1366/000370209787169777.

PMID:
19146716
25.

e-Science: relieving bottlenecks in large-scale genome analyses.

Craddock T, Harwood CR, Hallinan J, Wipat A.

Nat Rev Microbiol. 2008 Dec;6(12):948-54. doi: 10.1038/nrmicro2031. Review.

PMID:
19008893
26.

From genome to function: systematic analysis of the soil bacterium bacillus subtilis.

Harwood CR, Crawshaw SG, Wipat A.

Comp Funct Genomics. 2001;2(1):22-4. doi: 10.1002/cfg.69.

27.

From gene regulation to gene function: regulatory networks in bacillus subtilis.

Harwood CR, Moszer I.

Comp Funct Genomics. 2002;3(1):37-41. doi: 10.1002/cfg.138.

28.

Bacillus protein secretion: an unfolding story.

Harwood CR, Cranenburgh R.

Trends Microbiol. 2008 Feb;16(2):73-9. doi: 10.1016/j.tim.2007.12.001. Epub 2008 Jan 7. Review.

PMID:
18182292
29.

Phosphate starvation induces the sporulation killing factor of Bacillus subtilis.

Allenby NE, Watts CA, Homuth G, Prágai Z, Wipat A, Ward AC, Harwood CR.

J Bacteriol. 2006 Jul;188(14):5299-303.

30.

Predicting metals sensed by ArsR-SmtB repressors: allosteric interference by a non-effector metal.

Harvie DR, Andreini C, Cavallaro G, Meng W, Connolly BA, Yoshida K, Fujita Y, Harwood CR, Radford DS, Tottey S, Cavet JS, Robinson NJ.

Mol Microbiol. 2006 Feb;59(4):1341-56.

31.

Genome-wide transcriptional analysis of the phosphate starvation stimulon of Bacillus subtilis.

Allenby NE, O'Connor N, Prágai Z, Ward AC, Wipat A, Harwood CR.

J Bacteriol. 2005 Dec;187(23):8063-80.

32.

The extracellular and cytoplasmic proteomes of the non-virulent Bacillus anthracis strain UM23C1-2.

Antelmann H, Williams RC, Miethke M, Wipat A, Albrecht D, Harwood CR, Hecker M.

Proteomics. 2005 Sep;5(14):3684-95.

PMID:
16121336
33.

Post-translocational folding of secretory proteins in Gram-positive bacteria.

Sarvas M, Harwood CR, Bron S, van Dijl JM.

Biochim Biophys Acta. 2004 Nov 11;1694(1-3):311-27. Review.

34.

Post-transcriptional regulation of the Bacillus subtilis pst operon encoding a phosphate-specific ABC transporter.

Allenby NE, O'Connor N, Prágai Z, Carter NM, Miethke M, Engelmann S, Hecker M, Wipat A, Ward AC, Harwood CR.

Microbiology. 2004 Aug;150(Pt 8):2619-28.

PMID:
15289558
35.

Transcriptional regulation of the phoPR operon in Bacillus subtilis.

Prágai Z, Allenby NE, O'Connor N, Dubrac S, Rapoport G, Msadek T, Harwood CR.

J Bacteriol. 2004 Feb;186(4):1182-90.

36.

Essential Bacillus subtilis genes.

Kobayashi K, Ehrlich SD, Albertini A, Amati G, Andersen KK, Arnaud M, Asai K, Ashikaga S, Aymerich S, Bessieres P, Boland F, Brignell SC, Bron S, Bunai K, Chapuis J, Christiansen LC, Danchin A, Débarbouille M, Dervyn E, Deuerling E, Devine K, Devine SK, Dreesen O, Errington J, Fillinger S, Foster SJ, Fujita Y, Galizzi A, Gardan R, Eschevins C, Fukushima T, Haga K, Harwood CR, Hecker M, Hosoya D, Hullo MF, Kakeshita H, Karamata D, Kasahara Y, Kawamura F, Koga K, Koski P, Kuwana R, Imamura D, Ishimaru M, Ishikawa S, Ishio I, Le Coq D, Masson A, Mauël C, Meima R, Mellado RP, Moir A, Moriya S, Nagakawa E, Nanamiya H, Nakai S, Nygaard P, Ogura M, Ohanan T, O'Reilly M, O'Rourke M, Pragai Z, Pooley HM, Rapoport G, Rawlins JP, Rivas LA, Rivolta C, Sadaie A, Sadaie Y, Sarvas M, Sato T, Saxild HH, Scanlan E, Schumann W, Seegers JF, Sekiguchi J, Sekowska A, Séror SJ, Simon M, Stragier P, Studer R, Takamatsu H, Tanaka T, Takeuchi M, Thomaides HB, Vagner V, van Dijl JM, Watabe K, Wipat A, Yamamoto H, Yamamoto M, Yamamoto Y, Yamane K, Yata K, Yoshida K, Yoshikawa H, Zuber U, Ogasawara N.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4678-83. Epub 2003 Apr 7.

37.

CopZ from Bacillus subtilis interacts in vivo with a copper exporting CPx-type ATPase CopA.

Radford DS, Kihlken MA, Borrelly GP, Harwood CR, Le Brun NE, Cavet JS.

FEMS Microbiol Lett. 2003 Mar 14;220(1):105-12.

38.

Production of Bacillus anthracis protective antigen is dependent on the extracellular chaperone, PrsA.

Williams RC, Rees ML, Jacobs MF, Prágai Z, Thwaite JE, Baillie LW, Emmerson PT, Harwood CR.

J Biol Chem. 2003 May 16;278(20):18056-62. Epub 2003 Feb 26.

39.

Active but nonculturable cells of Salmonella enterica serovar Typhimurium do not infect or colonize mice.

Smith RJ, Newton AT, Harwood CR, Barer MR.

Microbiology. 2002 Sep;148(Pt 9):2717-26.

PMID:
12213918
40.

Simultaneous inactivation of the wprA and dltB genes of Bacillus subtilis reduces the yield of alpha-amylase.

Stephenson K, Jensen CL, Jørgensen ST, Harwood CR.

Lett Appl Microbiol. 2002;34(6):394-7.

41.
42.

Optimization of the cell wall microenvironment allows increased production of recombinant Bacillus anthracis protective antigen from B. subtilis.

Thwaite JE, Baillie LW, Carter NM, Stephenson K, Rees M, Harwood CR, Emmerson PT.

Appl Environ Microbiol. 2002 Jan;68(1):227-34.

43.
44.
45.
46.

The influence of secretory-protein charge on late stages of secretion from the Gram-positive bacterium Bacillus subtilis.

Stephenson K, Jensen CL, Jørgensen ST, Lakey JH, Harwood CR.

Biochem J. 2000 Aug 15;350 Pt 1:31-9.

47.

D-Alanine substitution of teichoic acids as a modulator of protein folding and stability at the cytoplasmic membrane/cell wall interface of Bacillus subtilis.

Hyyrylainen HL, Vitikainen M, Thwaite J, Wu H, Sarvas M, Harwood CR, Kontinen VP, Stephenson K.

J Biol Chem. 2000 Sep 1;275(35):26696-703.

48.

Transcriptional analysis of the Bacillus subtilis teichuronic acid operon.

Lahooti M, Harwood CR.

Microbiology. 1999 Dec;145 ( Pt 12):3409-17.

PMID:
10627039
49.

Bacterial viability and culturability.

Barer MR, Harwood CR.

Adv Microb Physiol. 1999;41:93-137. Review.

PMID:
10500845
50.

Different mechanisms for thermal inactivation of Bacillus subtilis signal peptidase mutants.

Bolhuis A, Tjalsma H, Stephenson K, Harwood CR, Venema G, Bron S, van Dijl JM.

J Biol Chem. 1999 May 28;274(22):15865-8.

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