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Items: 32

1.

Cytotoxicity of thiazolidinedione-, oxazolidinedione- and pyrrolidinedione-ring containing compounds in HepG2 cells.

Keil AM, Frederick DM, Jacinto EY, Kennedy EL, Zauhar RJ, West NM, Tchao R, Harvison PJ.

Toxicol In Vitro. 2015 Oct;29(7):1887-96. doi: 10.1016/j.tiv.2015.07.015. Epub 2015 Jul 17.

2.

Cytotoxicity of 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione (DCPT) and analogues in wild type and CYP3A4 stably transfected HepG2 cells.

Frederick DM, Jacinto EY, Patel NN, Rushmore TH, Tchao R, Harvison PJ.

Toxicol In Vitro. 2011 Dec;25(8):2113-9. doi: 10.1016/j.tiv.2011.09.015. Epub 2011 Sep 22.

3.

Effect of structural modifications on 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione-induced hepatotoxicity in Fischer 344 rats.

Patel NN, Crincoli CM, Frederick DM, Tchao R, Harvison PJ.

J Appl Toxicol. 2012 Feb;32(2):108-17. doi: 10.1002/jat.1639. Epub 2011 Feb 21.

4.

Role of biotransformation in 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione-induced hepatotoxicity in Fischer 344 rats.

Crincoli CM, Patel NN, Tchao R, Harvison PJ.

Toxicology. 2008 Sep 4;250(2-3):100-8. doi: 10.1016/j.tox.2008.06.006. Epub 2008 Jun 25.

5.

Effect of gender, dose, and time on 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione (DCPT)-induced hepatotoxicity in Fischer 344 rats.

Patel NN, Crincoli CM, Kennedy EL, Frederick DM, Tchao R, Harvison PJ.

Xenobiotica. 2008 Apr;38(4):435-49. doi: 10.1080/00498250701830267 .

6.

Transamination in the metabolism of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide in rats.

Cui D, Rankin GO, Harvison PJ.

Drug Metab Dispos. 2005 Dec;33(12):1765-70. Epub 2005 Sep 20.

PMID:
16174804
11.
12.
13.

Cytochrome P450-mediated metabolism and nephrotoxicity of N-(3,5-dichlorophenyl)succinimide in Fischer 344 rats.

Nyarko AK, Kellner-Weibel GL, Harvison PJ.

Fundam Appl Toxicol. 1997 Jun;37(2):117-24.

PMID:
9242584
14.

The effect of aromatic fluorine substitution on the nephrotoxicity and metabolism of N-(3,5-dichlorophenyl)succinimide in Fischer 344 rats.

Kellner-Weibel GL, Nyarko AK, Tchao R, Henesey CM, Harvison PJ.

Toxicology. 1997 Feb 14;117(1):73-83.

PMID:
9020201
15.
17.

Nephrotoxic potential of N-(3,5-dichlorophenyl)glutarimide and N-(3,5-dichlorophenyl)glutaramic acid in Fischer 344 rats.

Kellner-Weibel GL, Tchao R, Harvison PJ.

Toxicol Lett. 1995 Oct;80(1-3):123-9.

PMID:
7482579
18.

Metabolism of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide by isolated rat hepatocytes.

Nyarko AK, Harvison PJ.

Drug Metab Dispos. 1995 Jan;23(1):107-12.

PMID:
7720512
19.
20.

Nephrotoxic potential of N-(3,5-dichloro-4-hydroxyphenyl)succinimide and N-(3,5-dichloro-4-hydroxyphenyl)succinamic acid in Fischer-344 rats.

Harvison PJ, Griffin RJ, Teets VJ, Nicoll DW, Brown PI, Rankin GO.

Toxicol Lett. 1992 Apr;60(2):221-6.

PMID:
1570636
21.
22.

Comparative cytotoxic effects of N-acetyl-p-benzoquinone imine and two dimethylated analogues.

Rundgren M, Porubek DJ, Harvison PJ, Cotgreave IA, Moldéus P, Nelson SD.

Mol Pharmacol. 1988 Oct;34(4):566-72.

PMID:
3173335
23.

Evaluation of pteroyl-S-alkylhomocysteine sulfoximines as inhibitors of mammalian folylpolyglutamate synthetase.

Moran RG, Colman PD, Harvison PJ, Kalman TI.

Biochem Pharmacol. 1988 May 15;37(10):1997-2003.

PMID:
3377808
24.

Toxic effects of paracetamol and related structures in V79 Chinese hamster cells.

Holme JA, Hongslo JK, Bjørnstad C, Harvison PJ, Nelson SD.

Mutagenesis. 1988 Jan;3(1):51-6.

PMID:
3282144
25.

Acetaminophen and analogs as cosubstrates and inhibitors of prostaglandin H synthase.

Harvison PJ, Egan RW, Gale PH, Christian GD, Hill BS, Nelson SD.

Chem Biol Interact. 1988;64(3):251-66.

PMID:
3124965
26.

Cytochrome P-450 isozyme selectivity in the oxidation of acetaminophen.

Harvison PJ, Guengerich FP, Rashed MS, Nelson SD.

Chem Res Toxicol. 1988 Jan-Feb;1(1):47-52.

PMID:
2979711
27.
28.

Comparative toxicities and analgesic activities of three monomethylated analogues of acetaminophen.

Harvison PJ, Forte AJ, Nelson SD.

J Med Chem. 1986 Sep;29(9):1737-43.

PMID:
3746820
29.

Cross-linking of protein molecules by the reactive metabolite of acetaminophen, N-acetyl-p-benzoquinone imine, and related quinoid compounds.

Streeter AJ, Harvison PJ, Nelson SD, Baillie TA.

Adv Exp Med Biol. 1986;197:727-37. No abstract available.

PMID:
3766291
30.

Acetaminophen as a cosubstrate and inhibitor of prostaglandin H synthase.

Harvison PJ, Egan RW, Gale PH, Nelson SD.

Adv Exp Med Biol. 1986;197:739-47. No abstract available.

PMID:
3094341
31.

Formation of 4-aminophenoxyl free radical from the acetaminophen metabolite N-acetyl-p-benzoquinone imine.

Fischer V, West PR, Nelson SD, Harvison PJ, Mason RP.

J Biol Chem. 1985 Sep 25;260(21):11446-50.

32.

Mechanisms of N-acetyl-p-benzoquinone imine cytotoxicity.

Albano E, Rundgren M, Harvison PJ, Nelson SD, Moldéus P.

Mol Pharmacol. 1985 Sep;28(3):306-11.

PMID:
4033631

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