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Items: 1 to 50 of 261

1.

Queer Youth in Family Therapy.

Harvey RG, Stone Fish L.

Fam Process. 2015 Sep;54(3):396-417. doi: 10.1111/famp.12170. Epub 2015 Aug 18. Review.

PMID:
26283240
2.

Synthesis of 13C4-labelled oxidized metabolites of the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyrene.

Wu A, Xu D, Lu D, Penning TM, Blair IA, Harvey RG.

Tetrahedron. 2012 Sep 1;68(35). doi: 10.1016/j.tet.2012.05.130.

3.

Metabolism and distribution of benzo[a]pyrene-7,8-dione (B[a]P-7,8-dione) in human lung cells by liquid chromatography tandem mass spectrometry: detection of an adenine B[a]P-7,8-dione adduct.

Huang M, Liu X, Basu SS, Zhang L, Kushman ME, Harvey RG, Blair IA, Penning TM.

Chem Res Toxicol. 2012 May 21;25(5):993-1003. doi: 10.1021/tx200463s. Epub 2012 May 1.

4.
5.

Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone.

Shultz CA, Quinn AM, Park JH, Harvey RG, Bolton JL, Maser E, Penning TM.

Chem Res Toxicol. 2011 Dec 19;24(12):2153-66. doi: 10.1021/tx200294c. Epub 2011 Sep 29.

6.

Detoxication of structurally diverse polycyclic aromatic hydrocarbon (PAH) o-quinones by human recombinant catechol-O-methyltransferase (COMT) via O-methylation of PAH catechols.

Zhang L, Jin Y, Chen M, Huang M, Harvey RG, Blair IA, Penning TM.

J Biol Chem. 2011 Jul 22;286(29):25644-54. doi: 10.1074/jbc.M111.240739. Epub 2011 May 27.

7.

Regulation of benzo[a]pyrene-mediated DNA- and glutathione-adduct formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in human lung cells.

Gelhaus SL, Harvey RG, Penning TM, Blair IA.

Chem Res Toxicol. 2011 Jan 14;24(1):89-98. doi: 10.1021/tx100297z. Epub 2010 Oct 28.

8.

Regiospecific oxidation of polycyclic aromatic phenols to quinones by hypervalent iodine reagents.

Wu A, Duan Y, Xu D, Penning TM, Harvey RG.

Tetrahedron. 2010 Mar 20;66(12):2111-2118.

9.

Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2'-deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8-dione.

Park JH, Mangal D, Frey AJ, Harvey RG, Blair IA, Penning TM.

J Biol Chem. 2009 Oct 23;284(43):29725-34. doi: 10.1074/jbc.M109.042143. Epub 2009 Sep 2.

10.

Synthesis of phenol and quinone metabolites of benzo[a]pyrene, a carcinogenic component of tobacco smoke implicated in lung cancer.

Xu D, Penning TM, Blair IA, Harvey RG.

J Org Chem. 2009 Jan 16;74(2):597-604. doi: 10.1021/jo801864m.

11.

Oxidation of PAH trans-dihydrodiols by human aldo-keto reductase AKR1B10.

Quinn AM, Harvey RG, Penning TM.

Chem Res Toxicol. 2008 Nov;21(11):2207-15. doi: 10.1021/tx8002005.

12.

Synthesis of 13C2-Benzo[a]pyrene and its 7,8-Dihydrodiol and 7,8-Dione Implicated as Carcinogenic Metabolites.

Ran C, Xu D, Dai Q, Penning TM, Blair IA, Harvey RG.

Tetrahedron Lett. 2008 Jul 21;49(29-30):4531-4533.

13.

Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells.

Park JH, Mangal D, Tacka KA, Quinn AM, Harvey RG, Blair IA, Penning TM.

Proc Natl Acad Sci U S A. 2008 May 13;105(19):6846-51. doi: 10.1073/pnas.0802776105. Epub 2008 May 12.

14.

Synthesis of dibenzo[def,p]chrysene, its active metabolites, and their 13C-labeled analogues.

Xu D, Duan Y, Blair IA, Penning TM, Harvey RG.

Org Lett. 2008 Mar 20;10(6):1059-62. doi: 10.1021/ol7029323. Epub 2008 Feb 20.

PMID:
18284245
15.

Fjord-region benzo[g]chrysene-11,12-dihydrodiol and benzo[c]phenanthrene-3,4-dihydrodiol as substrates for rat liver dihydrodiol dehydrogenase (AKR1C9): structural basis for stereochemical preference.

Shultz CA, Palackal NT, Mangal D, Harvey RG, Blair IA, Penning TM.

Chem Res Toxicol. 2008 Mar;21(3):668-77. doi: 10.1021/tx7003695. Epub 2008 Feb 6.

16.

Strategies for synthesis of adducts of omicron-quinone metabolites of carcinogenic polycyclic aromatic hydrocarbons with 2'-deoxyribonucleosides.

Ran C, Dai Q, Ruan Q, Penning TM, Blair IA, Harvey RG.

J Org Chem. 2008 Feb 1;73(3):992-1003. doi: 10.1021/jo701667u. Epub 2008 Jan 9.

PMID:
18181642
17.

Metabolism of benzo[a]pyrene in human bronchoalveolar H358 cells using liquid chromatography-mass spectrometry.

Jiang H, Gelhaus SL, Mangal D, Harvey RG, Blair IA, Penning TM.

Chem Res Toxicol. 2007 Sep;20(9):1331-41. Epub 2007 Aug 17.

18.

Substituent effects in benz[a]anthracene carbocations: a stable ion, electrophilic substitution (nitration, bromination), and DFT study.

Laali KK, Arrica MA, Okazaki T, Harvey RG.

J Org Chem. 2007 Aug 31;72(18):6768-75. Epub 2007 Aug 4.

PMID:
17676909
19.
20.

Aldo-keto reductase- and cytochrome P450-dependent formation of benzo[a]pyrene-derived DNA adducts in human bronchoalveolar cells.

Ruan Q, Gelhaus SL, Penning TM, Harvey RG, Blair IA.

Chem Res Toxicol. 2007 Mar;20(3):424-31. Epub 2007 Feb 13.

PMID:
17295519
22.

Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry.

Ruan Q, Kim HY, Jiang H, Penning TM, Harvey RG, Blair IA.

Rapid Commun Mass Spectrom. 2006;20(8):1369-80.

PMID:
16557497
23.
24.

N6-Arylation of 2'-deoxyadenosine via copper-catalyzed direct coupling with aryl halides.

Ran C, Dai Q, Harvey RG.

J Org Chem. 2005 Apr 29;70(9):3724-6.

PMID:
15845015
25.
26.

Self-assembled polynuclear clusters derived from some flexible polydentate dihydrazide ligands.

Zhao L, Niel V, Thompson LK, Xu Z, Milway VA, Harvey RG, Miller DO, Wilson C, Leech M, Howard JA, Heath SL.

Dalton Trans. 2004 May 7;(9):1446-55. Epub 2004 Mar 30.

PMID:
15252640
27.

Supramolecular Mn(II) and Mn(II)/Mn(III) grid complexes with [Mn9(mu2-O)12] core structures. Structural, magnetic, and redox properties and surface studies.

Zhao L, Xu Z, Grove H, Milway VA, Dawe LN, Abedin TS, Thompson LK, Kelly TL, Harvey RG, Miller DO, Weeks L, Shapter JG, Pope KJ.

Inorg Chem. 2004 Jun 28;43(13):3812-24.

PMID:
15206861
28.
29.

A convenient new synthesis of benzo[a]pyrene.

Harvey RG, Lim K, Dai Q.

J Org Chem. 2004 Feb 20;69(4):1372-3.

PMID:
14961695
30.

Kidney transplants in cats.

Harvey RG, Mooney CT.

Vet Rec. 2003 Mar 29;152(13):407. No abstract available.

PMID:
12696713
31.

Polycyclic aromatic hydrocarbon o-quinones inhibit the activity of the catalytic fragment of protein kinase C.

Yu D, Kazanietz MG, Harvey RG, Penning TM.

Biochemistry. 2002 Oct 1;41(39):11888-94.

PMID:
12269833
32.
34.

Synthesis of Benzo[s]picene and its Putative Carcinogenic trans-3,4-Dihydrodiol and Fjord Region anti-Diol Epoxide Metabolites.

Harvey RG, Zhang JT, Luna E, Pataki J.

J Org Chem. 1998 Sep 4;63(18):6405-6408. No abstract available.

PMID:
11672279
35.

Efficient Synthesis of the Carcinogenic anti-Diol Epoxide Metabolite of 5-Methylchrysene.

Zhang FJ, Harvey RG.

J Org Chem. 1998 Apr 17;63(8):2771-2773. No abstract available.

PMID:
11672155
36.
38.

Metabolic activation of polycyclic aromatic hydrocarbon trans-dihydrodiols by ubiquitously expressed aldehyde reductase (AKR1A1).

Palackal NT, Burczynski ME, Harvey RG, Penning TM.

Chem Biol Interact. 2001 Jan 30;130-132(1-3):815-24.

PMID:
11306097
39.

Both (+/-)syn- and (+/-)anti-7,12-dimethylbenz[a]anthracene-3,4-diol-1,2-epoxides initiate tumors in mouse skin that possess -CAA- to -CTA- mutations at Codon 61 of c-H-ras.

Tang MS, Vulimiri SV, Viaje A, Chen JX, Bilolikar DS, Morris RJ, Harvey RG, Slaga TJ, DiGiovanni J.

Cancer Res. 2000 Oct 15;60(20):5688-95.

40.

7H-benzo[c]fluorene: a major DNA adduct-forming component of coal tar.

Koganti A, Singh R, Rozett K, Modi N, Goldstein LS, Roy TA, Zhang FJ, Harvey RG, Weyand EH.

Carcinogenesis. 2000 Aug;21(8):1601-9.

PMID:
10910965
42.

Mutagenicity of benzo[a]pyrene-deoxyadenosine adducts in a sequence context derived from the p53 gene.

Khalili H, Zhang FJ, Harvey RG, Dipple A.

Mutat Res. 2000 Feb 16;465(1-2):39-44.

PMID:
10708967
43.
44.

Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: oxidation of trans-7, 8-dihydroxy-7,8-dihydrobenzo

Burczynski ME, Harvey RG, Penning TM.

Biochemistry. 1999 Aug 10;38(32):10626. No abstract available.

PMID:
10441160
46.

Metabolic activation of 4H-cyclopenta[def]chrysene in human mammary carcinoma MCF-7 cell cultures.

Agarwal R, Coffing SL, Baird WM, Harvey RG, Dipple A.

Chem Res Toxicol. 1999 May;12(5):437-41.

PMID:
10328754
47.

Reactions of dihydrodiol epoxides of 5-methylchrysene and 5, 6-dimethylchrysene with DNA and deoxyribonucleotides.

Szeliga J, Amin S, Zhang FJ, Harvey RG.

Chem Res Toxicol. 1999 Apr;12(4):347-52.

PMID:
10207124
48.

Analysis of highly polar DNA adducts formed in SENCAR mouse epidermis following topical application of dibenz[a,j]anthracene.

Vulimiri SV, Baer-Dubowska W, Harvey RG, Zhang JT, DiGiovanni J.

Chem Res Toxicol. 1999 Jan;12(1):60-7.

PMID:
9894019
49.
50.

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