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Items: 25


Genetic Interaction Screens in Schizosaccharomyces pombe Using the Pombe Epistasis Mapper (PEM) System and a Manual Colony Replicator.

Colson I, Hartsuiker E.

Cold Spring Harb Protoc. 2018 Feb 1;2018(2). doi: 10.1101/pdb.prot091967.


Genetic Interaction Score (S-Score) Calculation, Clustering, and Visualization of Genetic Interaction Profiles for Yeast.

Roguev A, Ryan CJ, Xu J, Colson I, Hartsuiker E, Krogan N.

Cold Spring Harb Protoc. 2018 Feb 1;2018(2). doi: 10.1101/pdb.prot091983.


High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast Schizosaccharomyces pombe.

Roguev A, Ryan CJ, Hartsuiker E, Krogan NJ.

Cold Spring Harb Protoc. 2018 Feb 1;2018(2). doi: 10.1101/pdb.top079905.


Deoxynucleoside Salvage in Fission Yeast Allows Rescue of Ribonucleotide Reductase Deficiency but Not Spd1-Mediated Inhibition of Replication.

Fleck O, Fahnøe U, Løvschal KV, Gasasira MU, Marinova IN, Kragelund BB, Carr AM, Hartsuiker E, Holmberg C, Nielsen O.

Genes (Basel). 2017 Apr 25;8(5). pii: E128. doi: 10.3390/genes8050128.


The DNA-Binding Domain of S. pombe Mrc1 (Claspin) Acts to Enhance Stalling at Replication Barriers.

Zech J, Godfrey EL, Masai H, Hartsuiker E, Dalgaard JZ.

PLoS One. 2015 Jul 22;10(7):e0132595. doi: 10.1371/journal.pone.0132595. eCollection 2015.


UV induced ubiquitination of the yeast Rad4-Rad23 complex promotes survival by regulating cellular dNTP pools.

Zhou Z, Humphryes N, van Eijk P, Waters R, Yu S, Kraehenbuehl R, Hartsuiker E, Reed SH.

Nucleic Acids Res. 2015 Sep 3;43(15):7360-70. doi: 10.1093/nar/gkv680. Epub 2015 Jul 6.


Detection of covalent DNA-bound Spo11 and topoisomerase complexes.

Hartsuiker E.

Methods Mol Biol. 2011;745:65-77. doi: 10.1007/978-1-61779-129-1_5.


Topoisomerase I regulates open chromatin and controls gene expression in vivo.

Durand-Dubief M, Persson J, Norman U, Hartsuiker E, Ekwall K.

EMBO J. 2010 Jul 7;29(13):2126-34. doi: 10.1038/emboj.2010.109. Epub 2010 Jun 4.


Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair.

Nakamura K, Kogame T, Oshiumi H, Shinohara A, Sumitomo Y, Agama K, Pommier Y, Tsutsui KM, Tsutsui K, Hartsuiker E, Ogi T, Takeda S, Taniguchi Y.

PLoS Genet. 2010 Jan 22;6(1):e1000828. doi: 10.1371/journal.pgen.1000828.


A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage.

Lloyd J, Chapman JR, Clapperton JA, Haire LF, Hartsuiker E, Li J, Carr AM, Jackson SP, Smerdon SJ.

Cell. 2009 Oct 2;139(1):100-11. doi: 10.1016/j.cell.2009.07.043.


Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.

Deshpande GP, Hayles J, Hoe KL, Kim DU, Park HO, Hartsuiker E.

DNA Repair (Amst). 2009 May 1;8(5):672-9. doi: 10.1016/j.dnarep.2009.01.016. Epub 2009 Mar 4.


Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA.

Hartsuiker E, Neale MJ, Carr AM.

Mol Cell. 2009 Jan 16;33(1):117-23. doi: 10.1016/j.molcel.2008.11.021.


Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions.

Hartsuiker E, Mizuno K, Molnar M, Kohli J, Ohta K, Carr AM.

Mol Cell Biol. 2009 Apr;29(7):1671-81. doi: 10.1128/MCB.01182-08. Epub 2009 Jan 12.


TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks.

El-Khamisy SF, Hartsuiker E, Caldecott KW.

DNA Repair (Amst). 2007 Oct 1;6(10):1485-95. Epub 2007 Jun 28.


Double-strand break repair and homologous recombination in Schizosaccharomyces pombe.

Raji H, Hartsuiker E.

Yeast. 2006 Oct 15;23(13):963-76. Review.


The meiotic recombination hot spot ura4A in Schizosaccharomyces pombe.

Baur M, Hartsuiker E, Lehmann E, Ludin K, Munz P, Kohli J.

Genetics. 2005 Feb;169(2):551-61. Epub 2004 Oct 16.


Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.

Yamada T, Mizuno K, Hirota K, Kon N, Wahls WP, Hartsuiker E, Murofushi H, Shibata T, Ohta K.

EMBO J. 2004 Apr 21;23(8):1792-803. Epub 2004 Feb 26.


A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

Marchetti MA, Kumar S, Hartsuiker E, Maftahi M, Carr AM, Freyer GA, Burhans WC, Huberman JA.

Proc Natl Acad Sci U S A. 2002 May 28;99(11):7472-7.


A 160-bp palindrome is a Rad50.Rad32-dependent mitotic recombination hotspot in Schizosaccharomyces pombe.

Farah JA, Hartsuiker E, Mizuno K, Ohta K, Smith GR.

Genetics. 2002 May;161(1):461-8.


Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair.

Hartsuiker E, Vaessen E, Carr AM, Kohli J.

EMBO J. 2001 Dec 3;20(23):6660-71.


Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.

Manolis KG, Nimmo ER, Hartsuiker E, Carr AM, Jeggo PA, Allshire RC.

EMBO J. 2001 Jan 15;20(1-2):210-21.


The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization.

Rudolph C, Kunz C, Parisi S, Lehmann E, Hartsuiker E, Fartmann B, Kramer W, Kohli J, Fleck O.

Mol Cell Biol. 1999 Jan;19(1):241-50.


Immunocytochemical techniques applied to meiotic chromosomes.

Heyting C, Dietrich AJ, de Jong JH, Hartsuiker E.

Methods Mol Biol. 1994;29:287-301. No abstract available.


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