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Items: 1 to 50 of 114

1.

Genomic Comparison Among Global Isolates of L. interrogans Serovars Copenhageni and Icterohaemorrhagiae Identified Natural Genetic Variation Caused by an Indel.

Santos LA, Adhikarla H, Yan X, Wang Z, Fouts DE, Vinetz JM, Alcantara LCJ, Hartskeerl RA, Goris MGA, Picardeau M, Reis MG, Townsend JP, Zhao H, Ko AI, Wunder EA Jr.

Front Cell Infect Microbiol. 2018 Jun 19;8:193. doi: 10.3389/fcimb.2018.00193. eCollection 2018.

2.

Assessment of animal hosts of pathogenic Leptospira in northern Tanzania.

Allan KJ, Halliday JEB, Moseley M, Carter RW, Ahmed A, Goris MGA, Hartskeerl RA, Keyyu J, Kibona T, Maro VP, Maze MJ, Mmbaga BT, Tarimo R, Crump JA, Cleaveland S.

PLoS Negl Trop Dis. 2018 Jun 7;12(6):e0006444. doi: 10.1371/journal.pntd.0006444. eCollection 2018 Jun.

3.

Environmental risk of leptospirosis infections in the Netherlands: Spatial modelling of environmental risk factors of leptospirosis in the Netherlands.

Rood EJJ, Goris MGA, Pijnacker R, Bakker MI, Hartskeerl RA.

PLoS One. 2017 Oct 24;12(10):e0186987. doi: 10.1371/journal.pone.0186987. eCollection 2017.

4.

Identification of cattle, buffaloes and rodents as reservoir animals of Leptospira in the District of Gampaha, Sri Lanka.

Denipitiya DT, Chandrasekharan NV, Abeyewickreme W, Hartskeerl RA, Hapugoda MD.

BMC Res Notes. 2017 Mar 23;10(1):134. doi: 10.1186/s13104-017-2457-4.

5.

Application of a real time Polymerase Chain Reaction (PCR) assay for the early diagnosis of human leptospirosis in Sri Lanka.

Denipitiya DT, Chandrasekharan NV, Abeyewickreme W, Hartskeerl CM, Hartskeerl RA, Jiffrey AM, Hapugoda MD.

Biologicals. 2016 Nov;44(6):497-502. doi: 10.1016/j.biologicals.2016.09.004. Epub 2016 Oct 2.

PMID:
27707560
6.

Characterization of Leptospira santarosai Serogroup Grippotyphosa Serovar Bananal Isolated from Capybara ( Hydrochaeris hydrochaeris ) in Brazil.

Moreno LZ, Miraglia F, Marvulo MF, Silva JC, Paula CD, Costa BL, Morais ZM, Ferreira F, Neto JS, Dellagostin OA, Hartskeerl RA, Vasconcellos SA, Moreno AM.

J Wildl Dis. 2016 Jul;52(3):688-93. doi: 10.7589/2015-09-245. Epub 2016 Jun 3.

PMID:
27258408
7.

Marked increase in leptospirosis infections in humans and dogs in the Netherlands, 2014.

Pijnacker R, Goris MG, Te Wierik MJ, Broens EM, van der Giessen JW, de Rosa M, Wagenaar JA, Hartskeerl RA, Notermans DW, Maassen K, Schimmer B.

Euro Surveill. 2016 Apr 28;21(17). doi: 10.2807/1560-7917.ES.2016.21.17.30211.

8.

Predominance of the ST143 and ST50 Leptospira clones in the urban rat populations of Peninsular Malaysia.

Benacer D, Mohd Zain SN, Ahmed AA, Mohd Khalid MK, Hartskeerl RA, Thong KL.

J Med Microbiol. 2016 Jun;65(6):574-7. doi: 10.1099/jmm.0.000262. Epub 2016 Apr 6. No abstract available.

PMID:
27058766
9.

Human Leptospirosis in Malaysia: Reviewing the Challenges After 8 Decades (1925-2012).

Benacer D, Thong KL, Verasahib KB, Galloway RL, Hartskeerl RA, Lewis JW, Mohd Zain SN.

Asia Pac J Public Health. 2016 May;28(4):290-302. doi: 10.1177/1010539516640350. Epub 2016 Apr 3. Review.

PMID:
27044535
10.

Profiling of Leptospira interrogans, L. santarosai, L. meyeri and L. borgpetersenii by SE-AFLP, PFGE and susceptibility testing--a continuous attempt at species and serovar differentiation.

Moreno LZ, Miraglia F, Lilenbaum W, Neto JS, Freitas JC, Morais ZM, Hartskeerl RA, da Costa BL, Vasconcellos SA, Moreno AM.

Emerg Microbes Infect. 2016 Mar 9;5:e17. doi: 10.1038/emi.2016.16.

11.

Epidemiology of human leptospirosis in Malaysia, 2004-2012.

Benacer D, Thong KL, Min NC, Bin Verasahib K, Galloway RL, Hartskeerl RA, Souris M, Mohd Zain SN.

Acta Trop. 2016 May;157:162-8. doi: 10.1016/j.actatropica.2016.01.031. Epub 2016 Feb 1.

PMID:
26844370
12.

Leptospira Serovars for Diagnosis of Leptospirosis in Humans and Animals in Africa: Common Leptospira Isolates and Reservoir Hosts.

Mgode GF, Machang'u RS, Mhamphi GG, Katakweba A, Mulungu LS, Durnez L, Leirs H, Hartskeerl RA, Belmain SR.

PLoS Negl Trop Dis. 2015 Dec 1;9(12):e0004251. doi: 10.1371/journal.pntd.0004251. eCollection 2015 Dec.

13.

Are Pathogenic Leptospira Species Agents of Community-Acquired Pneumonia? Case Reports of Leptospirosis Presenting as Pneumonia.

Gasem MH, Farida H, Ahmed A, Severin JA, Suryanto A, Isbandrio B, Verbrugh HA, Hartskeerl RA, van den Broek PJ.

J Clin Microbiol. 2016 Jan;54(1):197-9. doi: 10.1128/JCM.02093-15. Epub 2015 Oct 28.

14.

Markers of endothelial cell activation and immune activation are increased in patients with severe leptospirosis and associated with disease severity.

Goeijenbier M, Gasem MH, Meijers JC, Hartskeerl RA, Ahmed A, Goris MG, Isbandrio B, Schuller SS, Osterhaus AD, Martina BE, van Gorp EC, Nally JE, Wagenaar JF.

J Infect. 2015 Oct;71(4):437-46. doi: 10.1016/j.jinf.2015.05.016. Epub 2015 Jun 3.

PMID:
26048204
15.

Evolution of the RNase P RNA structural domain in Leptospira spp.

Ravishankar V, Ahmed A, Sivagnanam U, Muthuraman K, Karthikaichamy A, Wilson HA, Devendran A, Hartskeerl RA, Raj SM.

Res Microbiol. 2014 Dec;165(10):813-25. doi: 10.1016/j.resmic.2014.10.007. Epub 2014 Oct 23.

PMID:
25463388
16.

Multilocus sequence typing (MLST): markers for the traceability of pathogenic Leptospira strains.

Ahmed A, Ferreira AS, Hartskeerl RA.

Methods Mol Biol. 2015;1247:349-59. doi: 10.1007/978-1-4939-2004-4_25.

PMID:
25399108
17.

Direct detection and differentiation of pathogenic Leptospira species using a multi-gene targeted real time PCR approach.

Ferreira AS, Costa P, Rocha T, Amaro A, Vieira ML, Ahmed A, Thompson G, Hartskeerl RA, Inácio J.

PLoS One. 2014 Nov 14;9(11):e112312. doi: 10.1371/journal.pone.0112312. eCollection 2014.

18.

The role of leptospirosis reference laboratories.

Hartskeerl RA, Smythe LD.

Curr Top Microbiol Immunol. 2015;387:273-88. doi: 10.1007/978-3-662-45059-8_11. Review.

PMID:
25388139
19.

Leptospirosis in Sub-Saharan Africa: a systematic review.

de Vries SG, Visser BJ, Nagel IM, Goris MG, Hartskeerl RA, Grobusch MP.

Int J Infect Dis. 2014 Nov;28:47-64. doi: 10.1016/j.ijid.2014.06.013. Epub 2014 Sep 4. Review.

20.

The hanta hunting study: underdiagnosis of Puumala hantavirus infections in symptomatic non-travelling leptospirosis-suspected patients in the Netherlands, in 2010 and April to November 2011.

Goeijenbier M, Hartskeerl RA, Reimerink J, Verner-Carlsson J, Wagenaar JF, Goris MG, Martina BE, Lundkvist Å, Koopmans M, Osterhaus AD, van Gorp EC, Reusken CB.

Euro Surveill. 2014 Aug 14;19(32). pii: 20878.

21.

Preliminary Investigations on the Distribution of Leptospira Serovars in Domestic Animals in North-west Morocco.

Benkirane A, Noury S, Hartskeerl RA, Goris MG, Ahmed A, Nally JE.

Transbound Emerg Dis. 2016 Apr;63(2):e178-84. doi: 10.1111/tbed.12252. Epub 2014 Jul 26.

PMID:
25065690
22.

Development of a recombinase polymerase amplification assay for the detection of pathogenic Leptospira.

Ahmed A, van der Linden H, Hartskeerl RA.

Int J Environ Res Public Health. 2014 May 8;11(5):4953-64. doi: 10.3390/ijerph110504953.

23.

Leptospirosis serodiagnosis by the microscopic agglutination test.

Goris MG, Hartskeerl RA.

Curr Protoc Microbiol. 2014 Feb 6;32:Unit 12E.5.. doi: 10.1002/9780471729259.mc12e05s32.

PMID:
24510846
24.

Rapid tests for diagnosis of leptospirosis: current tools and emerging technologies.

Picardeau M, Bertherat E, Jancloes M, Skouloudis AN, Durski K, Hartskeerl RA.

Diagn Microbiol Infect Dis. 2014 Jan;78(1):1-8. doi: 10.1016/j.diagmicrobio.2013.09.012. Epub 2013 Oct 1. Review.

PMID:
24207075
25.

Towards the burden of human leptospirosis: duration of acute illness and occurrence of post-leptospirosis symptoms of patients in the Netherlands.

Goris MG, Kikken V, Straetemans M, Alba S, Goeijenbier M, van Gorp EC, Boer KR, Wagenaar JF, Hartskeerl RA.

PLoS One. 2013 Oct 3;8(10):e76549. doi: 10.1371/journal.pone.0076549. eCollection 2013.

26.

Urban leptospirosis in Africa: a cross-sectional survey of Leptospira infection in rodents in the Kibera urban settlement, Nairobi, Kenya.

Halliday JEB, Knobel DL, Allan KJ, de C Bronsvoort BM, Handel I, Agwanda B, Cutler SJ, Olack B, Ahmed A, Hartskeerl RA, Njenga MK, Cleaveland S, Breiman RF.

Am J Trop Med Hyg. 2013 Dec;89(6):1095-1102. doi: 10.4269/ajtmh.13-0415. Epub 2013 Sep 30.

27.

'Leptorapide' - a one-step assay for rapid diagnosis of human leptospirosis.

Brownlow T, Kavanagh OV, Logan EF, Hartskeerl RA, Savage R, Palmer MF, Krahl M, Mackie DP, Ellis WA.

Epidemiol Infect. 2014 Jun;142(6):1182-7. doi: 10.1017/S0950268813002112. Epub 2013 Sep 19.

PMID:
24048024
28.

Prospective evaluation of three rapid diagnostic tests for diagnosis of human leptospirosis.

Goris MG, Leeflang MM, Loden M, Wagenaar JF, Klatser PR, Hartskeerl RA, Boer KR.

PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2290. doi: 10.1371/journal.pntd.0002290. Print 2013.

29.

New serovars of Leptospira isolated from patients in Costa Rica: implications for public health.

Valverde Mde L, Goris MG, González V, Anchia ME, Díaz P, Ahmed A, Hartskeerl RA.

J Med Microbiol. 2013 Sep;62(Pt 9):1263-71. doi: 10.1099/jmm.0.058545-0. Epub 2013 Jun 20.

PMID:
23788592
30.

Human leptospirosis trends, the Netherlands, 1925-2008.

Goris MG, Boer KR, Duarte TA, Kliffen SJ, Hartskeerl RA.

Emerg Infect Dis. 2013 Mar;19(3):371-8. doi: 10.3201/eid1903.111260.

31.

A single multilocus sequence typing (MLST) scheme for seven pathogenic Leptospira species.

Boonsilp S, Thaipadungpanit J, Amornchai P, Wuthiekanun V, Bailey MS, Holden MT, Zhang C, Jiang X, Koizumi N, Taylor K, Galloway R, Hoffmaster AR, Craig S, Smythe LD, Hartskeerl RA, Day NP, Chantratita N, Feil EJ, Aanensen DM, Spratt BG, Peacock SJ.

PLoS Negl Trop Dis. 2013;7(1):e1954. doi: 10.1371/journal.pntd.0001954. Epub 2013 Jan 24.

32.

Surveillance for leptospirosis in the Americas, 1996-2005: a review of data from ministries of health.

Costa F, Martinez-Silveira MS, Hagan JE, Hartskeerl RA, Dos Reis MG, Ko AI.

Rev Panam Salud Publica. 2012 Sep;32(3):169-77. Review.

33.

Classification of Leptospira genomospecies 1, 3, 4 and 5 as Leptospira alstonii sp. nov., Leptospira vanthielii sp. nov., Leptospira terpstrae sp. nov. and Leptospira yanagawae sp. nov., respectively.

Smythe L, Adler B, Hartskeerl RA, Galloway RL, Turenne CY, Levett PN; International Committee on Systematics of Prokaryotes Subcommittee on the Taxonomy of Leptospiraceae.

Int J Syst Evol Microbiol. 2013 May;63(Pt 5):1859-62. doi: 10.1099/ijs.0.047324-0. Epub 2012 Sep 14.

PMID:
22984140
34.

Severe pulmonary manifestation of leptospirosis.

Helmerhorst HJ, van Tol EN, Tuinman PR, de Vries PJ, Hartskeerl RA, Grobusch MP, Hovius JW.

Neth J Med. 2012 Jun;70(5):215-21. Review.

35.

Molecular and serological characterization of Leptospira interrogans serovar Canicola isolated from dogs, swine, and bovine in Brazil.

Miraglia F, de Morais ZM, Dellagostin OA, Seixas FK, Freitas JC, Zacarias FG, Delbem AC, Ferreira TS, Souza GO, Hartskeerl RA, Vasconcellos SA, Moreno AM.

Trop Anim Health Prod. 2013 Jan;45(1):117-21. doi: 10.1007/s11250-012-0181-6. Epub 2012 May 20.

PMID:
22610538
36.

Development of a magnetic bead fluorescence microscopy immunoassay to detect and quantify Leptospira in environmental water samples.

Schreier S, Doungchawee G, Triampo D, Wangroongsarb P, Hartskeerl RA, Triampo W.

Acta Trop. 2012 Apr;122(1):119-25. doi: 10.1016/j.actatropica.2011.12.011. Epub 2012 Jan 5.

PMID:
22245149
37.

Human leptospira isolates circulating in Mayotte (Indian Ocean) have unique serological and molecular features.

Bourhy P, Collet L, Lernout T, Zinini F, Hartskeerl RA, van der Linden H, Thiberge JM, Diancourt L, Brisse S, Giry C, Pettinelli F, Picardeau M.

J Clin Microbiol. 2012 Feb;50(2):307-11. doi: 10.1128/JCM.05931-11. Epub 2011 Dec 7.

38.

Comparison of two multilocus sequence based genotyping schemes for Leptospira species.

Ahmed A, Thaipadungpanit J, Boonsilp S, Wuthiekanun V, Nalam K, Spratt BG, Aanensen DM, Smythe LD, Ahmed N, Feil EJ, Hartskeerl RA, Peacock SJ.

PLoS Negl Trop Dis. 2011 Nov;5(11):e1374. doi: 10.1371/journal.pntd.0001374. Epub 2011 Nov 8.

39.

Potent innate immune response to pathogenic leptospira in human whole blood.

Goris MG, Wagenaar JF, Hartskeerl RA, van Gorp EC, Schuller S, Monahan AM, Nally JE, van der Poll T, van 't Veer C.

PLoS One. 2011 Mar 31;6(3):e18279. doi: 10.1371/journal.pone.0018279.

40.

Interactions of leptospira with environmental bacteria from surface water.

Barragan VA, Mejia ME, Trávez A, Zapata S, Hartskeerl RA, Haake DA, Trueba GA.

Curr Microbiol. 2011 Jun;62(6):1802-6. doi: 10.1007/s00284-011-9931-3. Epub 2011 Apr 10.

PMID:
21479795
41.

Emergence, control and re-emerging leptospirosis: dynamics of infection in the changing world.

Hartskeerl RA, Collares-Pereira M, Ellis WA.

Clin Microbiol Infect. 2011 Apr;17(4):494-501. doi: 10.1111/j.1469-0691.2011.03474.x. Review.

42.

Bioinformatics describes novel Loci for high resolution discrimination of leptospira isolates.

Cerqueira GM, McBride AJ, Hartskeerl RA, Ahmed N, Dellagostin OA, Eslabão MR, Nascimento AL.

PLoS One. 2010 Oct 15;5(10):e15335. doi: 10.1371/journal.pone.0015335.

43.

Agglutinating antibodies against pathogenic Leptospira in healthy dogs and horses indicate common exposure and regular occurrence of subclinical infections.

Houwers DJ, Goris MG, Abdoel T, Kas JA, Knobbe SS, van Dongen AM, Westerduin FE, Klein WR, Hartskeerl RA.

Vet Microbiol. 2011 Mar 24;148(2-4):449-51. doi: 10.1016/j.vetmic.2010.08.020. Epub 2010 Aug 27. No abstract available.

PMID:
20863632
44.

Mutations affecting Leptospira interrogans lipopolysaccharide attenuate virulence.

Murray GL, Srikram A, Henry R, Hartskeerl RA, Sermswan RW, Adler B.

Mol Microbiol. 2010 Nov;78(3):701-9. doi: 10.1111/j.1365-2958.2010.07360.x. Epub 2010 Sep 14.

45.

Genetic affinities within a large global collection of pathogenic Leptospira: implications for strain identification and molecular epidemiology.

Nalam K, Ahmed A, Devi SM, Francalacci P, Baig M, Sechi LA, Hartskeerl RA, Ahmed N.

PLoS One. 2010 Aug 27;5(8):e12637. doi: 10.1371/journal.pone.0012637.

46.

Evaluation of the use of selective PCR amplification of LPS biosynthesis genes for molecular typing of leptospira at the serovar level.

Bezerra da Silva J, Carvalho E, Hartskeerl RA, Ho PL.

Curr Microbiol. 2011 Feb;62(2):518-24. doi: 10.1007/s00284-010-9738-7. Epub 2010 Aug 19. Erratum in: Curr Microbiol. 2011 Feb;62(2):525.

PMID:
20721667
47.

Estimating the burden of human leptospirosis.

Abela-Ridder B, Sikkema R, Hartskeerl RA.

Int J Antimicrob Agents. 2010 Nov;36 Suppl 1:S5-7. doi: 10.1016/j.ijantimicag.2010.06.012. Epub 2010 Aug 4. Review.

PMID:
20688484
48.

A simple and rapid molecular method for Leptospira species identification.

Ahmed A, Anthony RM, Hartskeerl RA.

Infect Genet Evol. 2010 Oct;10(7):955-62. doi: 10.1016/j.meegid.2010.06.002. Epub 2010 Jun 12.

PMID:
20547247
49.

Monitoring Leptospira strain collections: the need for quality control.

Cerqueira GM, McBride AJ, Queiroz A, Pinto LS, Silva EF, Hartskeerl RA, Reis MG, Ko AI, Dellagostin OA.

Am J Trop Med Hyg. 2010 Jan;82(1):83-7. doi: 10.4269/ajtmh.2010.09-0558.

50.

Coagulation disorders in patients with severe leptospirosis are associated with severe bleeding and mortality.

Wagenaar JF, Goris MG, Partiningrum DL, Isbandrio B, Hartskeerl RA, Brandjes DP, Meijers JC, Gasem MH, van Gorp EC.

Trop Med Int Health. 2010 Feb;15(2):152-9. doi: 10.1111/j.1365-3156.2009.02434.x. Epub 2009 Dec 9.

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